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| TIF1SummaryGene Symbol: TIF1 Description: Tif1p Species: Top Publications
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Publications
Posttranscriptional control of gene expression in yeastJ E McCarthy
Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology UMIST, Manchester M60 1QD, United Kingdom
Microbiol Mol Biol Rev 62:1492-553. 1998....- Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear exportFrancisco Estruch
Departamento de Bioquimica y Biologia Molecular, Facultad de Biologia, Universitat de Valencia, Dr Moliner, 50 Burjassot 46100, Spain
J Biol Chem 280:9691-7. 2005..We proposed that Zds1p associates with the complex formed by Dbp5p, Gfd1p, and nucleoporins at the cytosolic fibrils of the nuclear pore complex and is required for optimal mRNA export... - Puf1p acts in combination with other yeast Puf proteins to control mRNA stabilityRandi J Ulbricht
Department of Biology, University of Missouri St Louis, St Louis, Missouri 63121, USA
RNA 14:246-62. 2008..40 candidate mRNAs, we established two of these as true mRNA targets of Puf-mediated decay in yeast, HXK1 and TIF1. In a novel finding, multiple Puf proteins, including Puf1p, regulate both of these mRNAs in combination... - Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactionsPatrick Schütz
Departement fur Chemie und Biochemie, Universitat Bern, Freiestrasse 3, CH 3012 Bern, Switzerland
Proc Natl Acad Sci U S A 105:9564-9. 2008..Conformational changes between eIF4A's closed and open state provide a model for its RNA-helicase activity... - Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality controlAnna Deplazes
Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland or
EMBO J 28:1429-41. 2009..Together with genetic data, these interactions indicate that Uri1p may coordinate translation initiation and cotranslational quality control... - ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiaeS Blum
Institut fur Biochemie und Molekularbiologie, Universitat Bern, Switzerland
Proc Natl Acad Sci U S A 89:7664-8. 1992.... - Combining peptide recognition specificity and context information for the prediction of the 14-3-3-mediated interactome in S. cerevisiae and H. sapiensSimona Panni
Department of Biology, University of Rome Tor Vergata, Rome, Italy
Proteomics 11:128-43. 2011..Our approach provides an orthogonal reliability assessment and maps with high confidence the 14-3-3 peptide target on the partner proteins... - A yeast model for polyalanine-expansion aggregation and toxicityCatherine A Konopka
Department of Pharmacology, University of Washington, Seattle, USA
Mol Biol Cell 22:1971-84. 2011..Thus longer expansions may have a different mechanism for toxicity. We think that this difference underscores the potential need to examine the cytotoxic mechanisms of both long and short expansions in models of expansion disorders... - Diauxic shift-dependent relocalization of decapping activators Dhh1 and Pat1 to polysomal complexesSheona P Drummond
Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK
Nucleic Acids Res 39:7764-74. 2011..This reveals a new dimension to the relationship between translation activity and interactions between mRNA, the translation machinery and decapping activator proteins... - Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up-regulatedLydia M Castelli
University of Manchester, Manchester M13 9PT, UK
Mol Biol Cell 22:3379-93. 2011.... - Insights into the role of yeast eIF2A in IRES-mediated translationLucas C Reineke
Department of Biochemistry, Case Western Reserve University, School of Medicine, Cleveland, Ohio, United States of America
PLoS ONE 6:e24492. 2011..These data suggest that eIF2A acts as a switch to regulate IRES-mediated translation, and eEF1A may be an important mediator of translational activation during ethanol stress... - Functional conservation of Dhh1p, a cytoplasmic DExD/H-box protein present in large complexesStephanie S I Tseng-Rogenski
Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA
Nucleic Acids Res 31:4995-5002. 2003..Finally, similar to Ste13p, Dhh1p is required for sporulation in the budding yeast. Taken together, our data provide evidence that the functions of Dhh1p are conserved through evolution... - The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selectionHui He
Division of Biology, Kansas State University, Manhattan, KS 66506, USA
Mol Cell Biol 23:5431-45. 2003..These results strongly suggest that the binding of the eIF4G HEAT domain to eIF1 and eIF5 is important for maintaining the integrity of the scanning ribosomal preinitiation complex... - An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutationP Linder
Centre de Genetique Moleculaire du Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Gif sur Yvette, France
Proc Natl Acad Sci U S A 86:2286-90. 1989We describe the isolation and characterization of two previously undescribed genes, TIF1 and TIF2, from Saccharomyces cerevisiae... - A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicaseR Coppolecchia
Department of Microbiology, University of Basel, Switzerland
EMBO J 12:4005-11. 1993..The Stm1 protein has potential RNP1 and RNP2 motifs characteristic for RNA-binding proteins. The protein also contains six highly conserved direct repeats of 21-26 amino acids and one partial repeat... - Requirement of the DEAD-Box protein ded1p for messenger RNA translationR Y Chuang
Molecular, Cellular, and Developmental Biology Program, Ohio State University, Columbus, OH 43210, USA
Science 275:1468-71. 1997..The DED1 gene could be functionally replaced by a mouse homolog, PL10, which suggests that the function of Ded1p in translation is evolutionarily conserved... - The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiaeJ De la Cruz
Departement de Biochimie Medicale, CMU, 1, rue Michel Servet, 1211 Geneve 4, Switzerland
Proc Natl Acad Sci U S A 94:5201-6. 1997..cerevisiae... - Effects of deletion mutations in the yeast Ces1 protein on cell growth and morphology and on high copy suppression of mutations in mRNA capping enzyme and translation initiation factor 4AB Schwer
Department of Microbiology, Cornell University Medical College, New York, NY 10021, USA
Nucleic Acids Res 26:803-9. 1998..Deletion of the N-terminal 249 amino acids of Ces1p abolished tif1-A79V suppressor function. CES4 on a multicopy plasmid was unable to suppress tif1-A79V ... - Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionallyC L Neff
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
Mol Cell Biol 19:5557-64. 1999..In total, these data indicate that yeast eIF4G and eIF4A physically associate and that this association performs an essential function... - Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiaeD Dominguez
Institute for Biochemistry and Molecular Biology, University of Bern, Buhlstrasse 28, 3012 Bern, Switzerland
J Biol Chem 274:26720-6. 1999..These data demonstrate that yeast eIF4A and eIF4G interact and suggest that this interaction is required for translation and cell growth... - Coordinate regulation of sugar flux and translation by PAS kinaseJared Rutter
Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Cell 111:17-28. 2002..These studies provide evidence of a cell-autonomous signaling system that both controls and connects the balance of fuel consumption/storage to protein synthesis... - RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiaeCatherine Berset
Institute for Biochemistry and Molecular Biology, University of Berne, CH 3012 Bern, Switzerland
RNA 9:871-80. 2003..These data suggest that RNA-binding activity is required for eIF4G1 function... - Multiple TORC1-associated proteins regulate nitrogen starvation-dependent cellular differentiation in Saccharomyces cerevisiaeSunil Laxman
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
PLoS ONE 6:e26081. 2011.... - A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transitionYosef Kaplan
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv, 69978, Israel
Curr Genet 51:123-40. 2007..Finally, we discuss possible mechanisms of suppression by the cDNAs that imply cell cycle regulation by apparently unrelated processes, such as splicing, translation initiation and glycolysis...