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Genomes and GenesSpecies | SEC31SummaryGene Symbol: SEC31 Description: Sec31p Alias: WEB1 Species: Top Publications
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Publications
COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulumC Barlowe
Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley 94720
Cell 77:895-907. 1994..Because the overall cycle of budding driven by these two types of coats appears mechanistically similar, we propose that the coat structures be called COPI and COPII...- Sec16p potentiates the action of COPII proteins to bud transport vesiclesFrantisek Supek
Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, CA 94720, USA
J Cell Biol 158:1029-38. 2002..We propose that Sec16p nucleates a Sar1-GTP-dependent initiation of COPII assembly and serves to stabilize the coat to premature disassembly after Sar1p hydrolyzes GTP... - Self-assembly of minimal COPII cagesBruno Antonny
Institut de Pharmacologie Moleculaire et Cellulaire, CNRS, Valbonne, France
EMBO Rep 4:419-24. 2003..We suggest that these structures, which represent a minimal COPII cage, mimic the molecular organization of the membrane-associated COPII coat... - Structure and organization of coat proteins in the COPII cageStephan Fath
Howard Hughes Medical Institute and the Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Cell 129:1325-36. 2007..The vertex geometry involves four copies of the Sec31 beta-propeller that converge through their axial ends; there is no interdigitation of assembly units of the kind .. - Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREsS Springer
Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720 3202, USA
Science 281:698-700. 1998..The data suggest that transmembrane proteins can be taken up into COPII vesicles by direct interactions with the coat proteins and may play a structural role in the assembly of the COPII coat complex... - Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8K J Roberg
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
Genetics 147:1569-84. 1997..The LST7 gene encodes a novel protein. Together, these data indicate that SEC13, LST4, LST7, and LST8 function in the regulated delivery of Gap1p to the cell surface, perhaps as components of a post-Golgi secretory-vesicle coat... - COPII subunit interactions in the assembly of the vesicle coatD A Shaywitz
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Biol Chem 272:25413-6. 1997..is unable to complement a sec31Delta mutant and cannot rescue the secretion defect of a temperature-sensitive sec31 mutant at nonpermissive temperatures... - A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear poresS Siniossoglou
European Molecular Biology Laboratory, Heidelberg Federal Republic of Germany
Cell 84:265-75. 1996..Thus, the Nup84p complex in conjunction with Sec13-type proteins is required for correct nuclear pore biogenesis... - The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteinsN R Salama
Department of Molecular and Cell Biology, Howard Hughes Research Institute, University of California, Berkeley 94720
EMBO J 12:4073-82. 1993..The vesicles formed with the purified protein fractions are competent to fuse with the Golgi and are biochemically distinct from the ER membrane fraction from which they derive... - The use of liposomes to study COPII- and COPI-coated vesicle formation and membrane protein sortingK Matsuoka
Department of Molecular and Cell Biology, Howerd Hughes Medical Institute, University of California, Berkeley, CA 94706, USA
Methods 20:417-28. 2000..Therefore, both generation of coated vesicles and protein sorting into the vesicles can be reproduced with liposomes and purified proteins... - Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coatJames R R Whittle
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
J Cell Biol 190:347-61. 2010..The ACE1 protein Sec31 and Sec13 make a 2:2 tetramer that forms the edge element of the COPII outer coat... - Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitorCatherine Z Chen
Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 6401, USA
Genetics 168:1827-41. 2004.... - Selective protein exit from yeast endoplasmic reticulum in absence of functional COPII coat component Sec13pNetta Fatal
Program in Cellular Biotechnology, Institute of Biotechnology, Viikki Biocenter, 00014 University of Helsinki, Finland
Mol Biol Cell 13:4130-40. 2002..Thus, Hsp150 harbors two different signatures that regulate its ER exit. Our data show that transport vesicles lacking functional Sec13p can carry out ER-to-Golgi transport, but select only specific cargo protein(s) for ER exit... - A genetic link between the unfolded protein response and vesicle formation from the endoplasmic reticulumHironori Higashio
Research and Education Center for Genetic Information, Nara Institute of Science and Technology NAIST, Takayama, Ikoma, Nara 630 0101, Japan
Biochem Biophys Res Commun 296:568-74. 2002..These findings suggest that the activation of the UPR affects ER-to-Golgi transport via stimulation of COPII vesicle formation from the ER... - Sgf1p, a new component of the Sec34p/Sec35p complexD W Kim
Department of Cell Biology and Howard Hughes Medical Institute, Yale University, New Haven, CT, USA
Traffic 2:820-30. 2001..Although an earlier study suggested that Sec34p (Grd20p) is not required for protein secretion, we show here that the sec34-2 and sec35-1 mutations lead to a pleiotropic block in the secretion of all proteins into the growth medium... - Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiaeT Kurihara
Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA
Mol Biol Cell 11:983-98. 2000..Abundant proteins in the purified vesicles produced with Sec23p/Iss1p were indistinguishable from those in the regular COPII vesicles produced with Sec23p/Sec24p... - Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complexW J Belden
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
J Biol Chem 276:43040-8. 2001..The Erv25p tail sequence binds COPI and is responsible for returning this complex to the ER... - Structure of the Sec23p/24p and Sec13p/31p complexes of COPIIG Z Lederkremer
Department of Cell Biology, Center for Blood Research, Harvard Medical School, Boston, MA 02115 5701, USA
Proc Natl Acad Sci U S A 98:10704-9. 2001..Putting together the architecture of these Sec complexes with the interactions between their subunits and the appearance of the coat in COPII-coated vesicles, we present a model for COPII coat organization... - A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiaeSvetlana Dokudovskaya
Institut Jacques Monod, CNRS UMR 7592, Batiment Buffon, Paris, France
Mol Cell Proteomics 10:M110.006478. 2011..These data demonstrate that the SEA complex is an additional member of a family of membrane coating and vesicle tethering assemblies, extending the repertoire of protocoatomer-related complexes... - Purification of functional Sec13p-Sec31p complex, a subunit of COPII coatW J Belden
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
Methods Enzymol 329:438-43. 2001 - Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulumN R Salama
Department of Molecular and Cell Biology, Howard Hughes Research Institute, University of California, Berkeley 94720, USA
Mol Biol Cell 8:205-17. 1997..p150 is encoded by SEC31, a gene isolated in a genetic screen for mutations that accumulate unprocessed forms of the secretory protein .. - Shr3p mediates specific COPII coatomer-cargo interactions required for the packaging of amino acid permeases into ER-derived transport vesiclesC F Gilstring
Ludwig Institute for Cancer Research, S 171 77 Stockholm, Sweden
Mol Biol Cell 10:3549-65. 1999.... - LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulumK J Roberg
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Cell Biol 145:659-72. 1999..Together, these findings suggest that a specialized form of the COPII coat subunit, with Lst1p in place of Sec24p, is used for the efficient packaging of Pma1p into vesicles derived from the ER... - Surface structure of the COPII-coated vesicleK Matsuoka
Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3206, USA
Proc Natl Acad Sci U S A 98:13705-9. 2001..Partially uncoated profiles revealed strands of Sec13/31p stripped from the vesicle surface. We conclude that the coat subunits form layers displaced from the membrane surface in reverse order of addition to the coat... - Three ways to make a vesicleT Kirchhausen
Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
Nat Rev Mol Cell Biol 1:187-98. 2000..A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined...