TNFRSF10C

Summary

Gene Symbol: TNFRSF10C
Description: tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Alias: CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, TNF-related apoptosis-inducing ligand receptor 3, antagonist decoy receptor for TRAIL/Apo-2L, cytotoxic TRAIL receptor-3, decoy TRAIL receptor without death domain, decoy receptor 1, lymphocyte inhibitor of TRAIL, tumor necrosis factor receptor superfamily member 10C
Species: human

Top Publications

  1. ncbi Stress impairs performance in spatial water maze learning tasks
    C Holscher
    Department of Physiology, University College, Dublin, Ireland
    Behav Brain Res 100:225-35. 1999
  2. ncbi Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
    J P Sheridan
    Department of Molecular Oncology, Genentech, South San Francisco, CA 94080 4918, USA
    Science 277:818-21. 1997
  3. ncbi An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    G Pan
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA
    Science 277:815-8. 1997
  4. ncbi [The clinical use of an individually fitted nasal mask ("Freiburg Respiratory Mask") within the scope of a case report of controlled BiPAP ventilation]
    N Netzer
    Abteilung Pneumologie,
    Pneumologie 51:798-801. 1997
  5. ncbi Comparison of home and hospital care of advanced cancer patients
    V Ventafridda
    Pain Therapy and Palliative Care Division, National Cancer Institute, Milan, Italy
    Tumori 75:619-25. 1989
  6. ncbi Concurrent human infection with Leishmania donovani and Leishmania braziliensis braziliensis
    M P Oliveira Neto
    Evandro Chagas Hospital, Rio de Janeiro, Brazil
    Ann Trop Med Parasitol 80:587-92. 1986
  7. ncbi Three-dimensional head axis of rotation during tracking movements. A tool for assessing neck neuromechanical function
    J M Winters
    Arizona State University, Tempe
    Spine (Phila Pa 1976) 18:1178-85. 1993
  8. ncbi Vitamin B1 thiazole derivative reduces transmembrane current through ionic channels formed by toxins from black widow spider venom and sea anemone in planar phospholipid membranes
    Oleg Ya Shatursky
    Department of Neurochemistry, Palladin Institute of Biochemistry, Leontovich Str, 9, 01601, Kiev, Ukraine
    Biochim Biophys Acta 1768:207-17. 2007
  9. ncbi The benzodiazepine diazepam demonstrates the usefulness of Syrian hamsters as a model for anxiety testing: evaluation of other classes of anxiolytics in comparison to diazepam
    Robert L Gannon
    Department of Biology, Valdosta State University, Valdosta, GA 31698, USA
    Behav Brain Res 218:8-14. 2011
  10. ncbi In vitro acaricidal effect of tannin-rich plants against the cattle tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
    A Fernández-Salas
    Centro de Enseñanza, Investigación y Extensión en Ganadería Tropical, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, Martínez de la Torre, Veracruz, Mexico
    Vet Parasitol 175:113-8. 2011

Research Grants

  1. Impact of Antibiotics and Vaccines on the in vivo Evolution of S. pneumoniae
    Garth Ehrlich; Fiscal Year: 2009
  2. Waterpipe tobacco smoke: toxicant exposure and effects
    Thomas Eissenberg; Fiscal Year: 2009
  3. Waterpipe tobacco smoke: toxicant exposure and effects
    THOMAS EVAN EISSENBERG; Fiscal Year: 2010
  4. Self-report and behavioral reactivity to combined smoking cues
    Cynthia A Conklin; Fiscal Year: 2010
  5. Self-report and behavioral reactivity to combined smoking cues
    Cynthia Conklin; Fiscal Year: 2009
  6. TRAIL receptor in apoptosis and the immune system
    Astar Winoto; Fiscal Year: 2005
  7. Determinates of anti-HIV nucleic acid aptamer potency and resistance
    Donald Burke; Fiscal Year: 2009
  8. Transgenic Approaches to Evaluate IGF-I Role in Peak BMD
    Subburaman Mohan; Fiscal Year: 2010
  9. Role of Regulatory CD8 T Cells in Murine Asthma
    Roger S Thrall; Fiscal Year: 2010
  10. HLTH LIT, SOC SUPPORT,& HLTH: SURVEY OF MEDICARE ENROLLE
    Shoou Yih Lee; Fiscal Year: 2003

Detail Information

Publications155 found, 100 shown here

  1. ncbi Stress impairs performance in spatial water maze learning tasks
    C Holscher
    Department of Physiology, University College, Dublin, Ireland
    Behav Brain Res 100:225-35. 1999
    ..In a fear habituation task, unhandled rats preferred a dark over a well lit chamber more than handled animals did, but unhandled rats favoured the lit chamber more in an active avoidance task...
  2. ncbi Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
    J P Sheridan
    Department of Molecular Oncology, Genentech, South San Francisco, CA 94080 4918, USA
    Science 277:818-21. 1997
    ..The receptor designated decoy receptor 1 (DcR1) displayed properties of a glycophospholipid-anchored cell surface protein...
  3. ncbi An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    G Pan
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA
    Science 277:815-8. 1997
    ..An antagonist decoy receptor (designated as TRID for TRAIL receptor without an intracellular domain) that may explain the resistant phenotype of normal tissues was ..
  4. ncbi [The clinical use of an individually fitted nasal mask ("Freiburg Respiratory Mask") within the scope of a case report of controlled BiPAP ventilation]
    N Netzer
    Abteilung Pneumologie,
    Pneumologie 51:798-801. 1997
    ..normalise blood gases and clinical status of the patient in mechanical ventilation on BiPAP mode and additional 2 lit/min of oxygen insufflation via the mask (patient was refusing invasive ventilation) for 12 days due to mask leakage ..
  5. ncbi Comparison of home and hospital care of advanced cancer patients
    V Ventafridda
    Pain Therapy and Palliative Care Division, National Cancer Institute, Milan, Italy
    Tumori 75:619-25. 1989
    ..An approximate quantification of the costs shows that an average cost for a day's home care was about Lit. 52,500 as compared with Lit. 360,000 for a day's hospitalization.
  6. ncbi Concurrent human infection with Leishmania donovani and Leishmania braziliensis braziliensis
    M P Oliveira Neto
    Evandro Chagas Hospital, Rio de Janeiro, Brazil
    Ann Trop Med Parasitol 80:587-92. 1986
    ..from both the ulcer and the bone marrow by culturing in BHI-agar with rabbit blood and a liquid overlay of modified LIT medium...
  7. ncbi Three-dimensional head axis of rotation during tracking movements. A tool for assessing neck neuromechanical function
    J M Winters
    Arizona State University, Tempe
    Spine (Phila Pa 1976) 18:1178-85. 1993
    ..separated by 10-degree intervals, and were instructed to use a head pointer (laser) to track whatever target was lit. Various horizontal, vertical, and oblique target sequences were employed...
  8. ncbi Vitamin B1 thiazole derivative reduces transmembrane current through ionic channels formed by toxins from black widow spider venom and sea anemone in planar phospholipid membranes
    Oleg Ya Shatursky
    Department of Neurochemistry, Palladin Institute of Biochemistry, Leontovich Str, 9, 01601, Kiev, Ukraine
    Biochim Biophys Acta 1768:207-17. 2007
    ..via ionic channels produced by latrotoxins (alpha-latrotoxin (alpha-LT) and alpha-latroinsectotoxin (alpha-LIT)) from black widow spider venom and sea anemone toxin (RTX) in the bilayer lipid membranes (BLMs)...
  9. ncbi The benzodiazepine diazepam demonstrates the usefulness of Syrian hamsters as a model for anxiety testing: evaluation of other classes of anxiolytics in comparison to diazepam
    Robert L Gannon
    Department of Biology, Valdosta State University, Valdosta, GA 31698, USA
    Behav Brain Res 218:8-14. 2011
    ..open arms in the plus maze, displayed more exploratory behavior in the t-tube, and were quicker to enter a brightly lit exposed field in the Thatcher-Britton conflict test following injections of diazepam...
  10. ncbi In vitro acaricidal effect of tannin-rich plants against the cattle tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
    A Fernández-Salas
    Centro de Enseñanza, Investigación y Extensión en Ganadería Tropical, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, Martínez de la Torre, Veracruz, Mexico
    Vet Parasitol 175:113-8. 2011
    ..Larval immersion (LIT) and adult immersion (AIT) tests were used to evaluate the acaricidal effect of each of the lyophilized extracts ..
  11. ncbi Adaptive gene loss reflects differences in the visual ecology of basal vertebrates
    Wayne L Davies
    Department of Molecular Genetics, UCL Institute of Ophthalmology, London, UK
    Mol Biol Evol 26:1803-9. 2009
    ..opsin) genes (LWS, SWS1, SWS2, RhA, and RhB) in five different cone-like photoreceptors for life in a brightly lit environment exposed to a broad spectrum of light...
  12. ncbi Percutaneous transluminal valvuloplasty of calcific aortic stenosis in elderly patients. Role of noninvasive evaluation by Doppler echocardiography
    F Stammen
    Department of Cardiology, University Hospital Gasthuisberg, Leuven, Belgium
    Acta Cardiol 45:379-91. 1990
    ..4 +/- 0.1 to 0.6 +/- 0.2 cm2 (p less than 0.001). Cardiac output remained unchanged: 3.8 +/- 0.9 vs 3.8 +/- 0.8 lit/min...
  13. ncbi Communication towers, lights, and birds: successful methods of reducing the frequency of avian collisions
    Joelle Gehring
    Central Michigan University, Department of Biology, Mount Pleasant, Michigan 48859, USA
    Ecol Appl 19:505-14. 2009
    ..Kruskal-Wallis test, ANOVA, Student's t test, and multiple comparisons procedures determined that towers lit at night with only flashing lights were involved in significantly fewer avian fatalities than towers lit with ..
  14. ncbi Biomonitoring insecticide pollution using non-target soil microarthropods
    V C Joy
    Soil Ecology Laboratory, Department of Zoology, Visva Bharati University, Santinikatan, India
    J Environ Biol 26:571-7. 2005
    ..25 kg ai/ha = 16.25 lit/ha) and endosulfan 35EC (0.875 kg ai/ha = 2.5 lit/ha) applied at the seedling stages...
  15. ncbi Glycerophospholipid profiling by high-performance liquid chromatography/mass spectrometry using exact mass measurements and multi-stage mass spectrometric fragmentation experiments in parallel
    Eva Maria Hein
    ISAS Institute for Analytical Sciences, Bunsen Kirchhoff Str 11, 44139 Dortmund, Germany
    Rapid Commun Mass Spectrom 23:1636-46. 2009
    ..RP-HPLC) coupled to hybrid linear ion trap-Fourier transform ion cyclotron resonance mass spectrometry (LIT-FTICRMS) with electrospray ionization (ESI) in the negative ionization mode...
  16. ncbi Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
    N Mitsiades
    Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    Cancer Res 60:4122-9. 2000
    ..Two additional TRAIL receptors (DcR1 and DcR2) do not transmit an apoptotic signal and have been proposed to confer protection from TRAIL-induced ..
  17. ncbi Direct stimulation of apoptotic signaling by soluble Apo2l/tumor necrosis factor-related apoptosis-inducing ligand leads to selective killing of glioma cells
    I F Pollack
    Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Clin Cancer Res 7:1362-9. 2001
    ..Apo2L/TRAIL also binds to "decoy" receptors (DcR1 and DcR2) that can antagonize its interaction with DR4 and DR5...
  18. ncbi mRNA expression, functional profiling and multivariate classification of colon biopsy specimen by cDNA overall glass microarray
    Orsolya Galamb
    2nd Department of Internal Medicine, University Semmelweis, Budapest, Hungary
    World J Gastroenterol 12:6998-7006. 2006
    ..To understand the local pathophysiological alterations and gene ontology-based functional classification of colonic biopsies into inflammatory and neoplastic diseases...
  19. ncbi Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4
    L R Donahue
    Jackson Laboratory, Bar Harbor, Maine 04609
    J Endocrinol 136:91-104. 1993
    ..We used a genetic model of GH deficiency, the 'little' (gene symbol lit) mouse, to determine the GH regulation of IGF-I and its insulin-like growth factor-binding proteins (IGFBPs) and to ..
  20. ncbi The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: amplified caspase 8 is indispensable for combination-mediated massive cell death
    Dao M Nguyen
    Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer J 12:257-73. 2006
    ....
  21. ncbi Comparison of a high and a low intensity smoking cessation intervention in a dentistry setting in Sweden: a randomized trial
    Eva Nohlert
    Centre for Clinical Research, Uppsala University, Central Hospital, Vasteras, Sweden
    BMC Public Health 9:121. 2009
    ..The aim of the present study was to assess the relative effectiveness of a high intensity intervention compared with a low intensity intervention for smoking cessation support in a dental clinic setting...
  22. ncbi Persistent neonatal Borna disease virus (BDV) infection of the brain causes chronic emotional abnormalities in adult rats
    M V Pletnikov
    Laboratory of Pediatric and Respiratory Viral Diseases, CBER, FDA, Bethesda, MD 20892, USA
    Physiol Behav 66:823-31. 1999
    ..BDV-infected rats exhibited locomotor hyperactivity and elevated defecation in a highly aversive, brightly lit open field...
  23. ncbi An ethical lesson learned from the equestrian sculpture, "The Torch Bearers," at the University of Madrid Dental School
    Arden G Christen
    Department of Oral Biology, Indiana University Nicotine Dependence Program, Indiana University Schools of Dentistry and Medicine, Indianapolis, IN 46240 3541, USA
    J Hist Dent 55:160-4; discussion 171-85. 2007
    ..The lesson which Dean Zabalo taught that day was simple but profound. The lit torch of ethics, learning and values is essentially transmitted from generation to generation, as young students ..
  24. ncbi Testing a two-component model of face identification: effects of inversion, contrast reversal, and direction of lighting
    P A McMullen
    Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada
    Perception 29:609-19. 2000
    ..59 23-31) found additive effects of test orientation (upright or inverted) and direction of lighting (brow or chin lit) when they studied the inversion effect on face identification...
  25. ncbi Diagnoses of fipronil resistance in Brazilian cattle ticks (Rhipicephalus (Boophilus) microplus) using in vitro larval bioassays
    E Castro-Janer
    Departamento de Parasitologia, Facultad de Veterinaria, UDELAR, Montevideo, Uruguay
    Vet Parasitol 173:300-6. 2010
    ..3%) was primarily evaluated using the larvae immersion test (LIT) and the larval packet test (LPT), when a sufficient number of larvae was collected...
  26. ncbi A study of helical and planar waves on sea urchin sperm flagella, with a theory of how they are generated
    D M Woolley
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    J Exp Biol 204:1333-45. 2001
    ..apparent wave frequency and the roll frequency of the sperm head, the latter being detectable in some sperm when lit stroboscopically.) The planar wave has a meander shape...
  27. ncbi Definition of a diagnostic routine in individuals with inconclusive serology for Chagas disease
    Mariele Cristina Modolo Picka
    Department of Tropical Diseases and Imaging Diagnosis, Botucatu School of Medicine, Universidade Estadual Paulista, 18618 000 Botucatu, SP, Brazil
    Braz J Infect Dis 11:226-33. 2007
    ..TESA-cruzi were used for G1, G2 and G3, and parasitological methods xenodiagnosis, hemoculture and PCR-LIT were used for G2 and G3 individuals. ELISA, HAI and IFI were performed in 5 different blood samples in G2 and G3...
  28. ncbi Prevalence and severity of malocclusion in adolescent Kuwaitis
    Faraj Behbehani
    Department of Developmental and Preventive Sciences, Faculty of Dentistry, Kuwait University, Kuwait
    Med Princ Pract 14:390-5. 2005
    ..Our aim was to evaluate prevalence and severity of malocclusion in an adolescent Kuwaiti population...
  29. ncbi An automatic method to generate domain-specific investigator networks using PubMed abstracts
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Inform Decis Mak 7:17. 2007
    ..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...
  30. ncbi Optimizing a GC-MS method for screening of Stachybotrys mycotoxins in indoor environments
    Erica Bloom
    Lund University, Dept of Laboratory Medicine, Division of Medical Microbiology, Lund, Sweden
    J Environ Monit 9:151-6. 2007
    ..Verrucarol (VER) and trichodermol (TRID) are hydrolysis products of some major S. chartarum mycotoxins, i.e. macrocyclic trichothecenes and trichodermin...
  31. ncbi The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse chromosome 6
    S C Chua
    Laboratory of Human Behavior and Metabolism, Rockefeller University, New York, New York 10021
    Mamm Genome 4:555-9. 1993
    The little (lit) autosomal recessive mutation in the mouse causes dwarfism due to isolated growth hormone deficiency...
  32. ncbi ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe
    Jon B Carmichael
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7
    Mol Biol Cell 15:1425-35. 2004
    ..fission yeast Schizosaccharomyces pombe, three genes that function in the RNA interference (RNAi) pathway, ago1+, dcr1+, and rdp1+, have recently been shown to be important for timely formation of heterochromatin and accurate ..
  33. ncbi Correlated fluctuations of daytime skin temperature and vigilance
    Nico Romeijn
    Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
    J Biol Rhythms 26:68-77. 2011
    ..in a 2-day protocol, during which vigilance and skin temperature were assessed 4 times per day in a silent, dimly lit, temperature-controlled room...
  34. ncbi Distinct embryonic expression and localization of CBP and p300 histone acetyltransferases at the mouse alphaA-crystallin locus in lens
    Ying Yang
    Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, NY10461, USA
    J Mol Biol 369:917-26. 2007
    ..Its 5'-distal enhancer, DCR1, mediates regulation of alphaA-crystallin via FGF signaling, while its 3'-distal enhancer, DCR3, functions only in ..
  35. ncbi On the border: perimeter patrolling as a transitional exploratory phase in a diurnal rodent, the fat sand rat (Psammomys obesus)
    Reut Avni
    Department of Zoology, Tel Aviv University, 69978, Ramat Aviv, Israel
    Anim Cogn 11:311-8. 2008
    ..In the present study we tested a diurnal gerbil, the fat sand rat, Psammomys obesus, in both a lit and a dark open field in order to compare its exploratory behavior with that of nocturnal rodents...
  36. ncbi Expression of tumor necrosis factor-alpha-related apoptosis-inducing ligand and its receptors in rat testis during development
    Renée Grataroli
    Institut National de la Sante et de la Recherche Medicale, INSERM U 407, Communications Cellulaires en Biologie de la Reproduction, Faculté de médecine Lyon Sud, F 69921 Oullins Cedex, France
    Biol Reprod 66:1707-15. 2002
    ..Two additional TRAIL receptors, DcR1/TRAIL-R3 and DcR2/TRAIL-R4, lack functional death domains and act as decoy receptors for TRAIL...
  37. ncbi National smokefree law in New Zealand improves air quality inside bars, pubs and restaurants
    Nick Wilson
    Department of Public Health, University of Otago Wellington, Wellington, New Zealand
    BMC Public Health 7:85. 2007
    ....
  38. ncbi Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology
    Ranjana Pal
    National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, Aruna Asafali Road, New Delhi 110067, India
    Mol Cancer 9:303. 2010
    ....
  39. ncbi Investigation, by single photon ionisation (SPI)-time-of-flight mass spectrometry (TOFMS), of the effect of different cigarette-lighting devices on the chemical composition of the first cigarette puff
    Thomas Adam
    Division of Analytical Chemistry, Institute of Physics, University of Augsburg, 86159, Augsburg, Germany
    Anal Bioanal Chem 387:575-84. 2007
    ..smoke of the cigarette used for lighting and would be drawn into the mainstream smoke of the cigarette being lit. In contrast, smoke from the cigarette lit by the electric lighter contained slightly higher normalised amounts of ..
  40. ncbi Evaluation of Melbourne Edge Test contrast sensitivity measures in the visually impaired
    James S Wolffsohn
    Neurosciences Research Institute, Aston University, Birmingham B4 7ET UK
    Ophthalmic Physiol Opt 25:371-4. 2005
    ..This study aimed to assess differences in clinical expediency of the CS increment-matched new back-lit and original paper versions of the Melbourne Edge Test (MET) to determine the CS of the visually impaired.
  41. ncbi Light dependence of [3H]leucine incorporation in the oligotrophic North Pacific ocean
    Matthew J Church
    School of Marine Science, The College of William and Mary, Gloucester Point, Virginia 23062, USA
    Appl Environ Microbiol 70:4079-87. 2004
    ..The influence of irradiance on bacterial growth was evaluated in both the well-lit (5 to 25 m) and dimly lit regions of the upper ocean (75 to 100 m) to determine whether the bacterial response to ..
  42. ncbi Hand rolling cigarette papers as the reference point for regulating cigarette fire safety
    M Laugesen
    Health New Zealand, Auckland, New Zealand
    Tob Control 12:406-10. 2003
    ..To compare the burning characteristics of the tobacco and paper of manufactured and hand rolled cigarettes, and set a fire safety standard of manufacture to largely reduce the fire risk from discarded cigarettes...
  43. ncbi Light quality-mediated petiole elongation in Arabidopsis during shade avoidance involves cell wall modification by xyloglucan endotransglucosylase/hydrolases
    Rashmi Sasidharan
    Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, Utrecht, The Netherlands
    Plant Physiol 154:978-90. 2010
    Some plants can avoid shaded conditions via rapid shoot elongation, thus growing into better lit areas in a canopy...
  44. ncbi Evaluation of nephrolithiasis in autosomal dominant polycystic kidney disease patients
    José L Nishiura
    Nephrology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Clin J Am Soc Nephrol 4:838-44. 2009
    Nephrolithiasis (LIT) is more prevalent in patients with autosomal dominant polycystic kidney disease (ADPKD) than in the general population...
  45. ncbi Analysis of the lambdoid prophage element e14 in the E. coli K-12 genome
    Preeti Mehta
    Bioinformatics Centre, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, India
    BMC Microbiol 4:4. 2004
    ..coli K-12 genome. This prophage encodes important functional genes such as lit (T4 exclusion), mcrA (modified cytosine restriction activity) and pin (recombinase).
  46. ncbi Muscle loading as a method to isolate the underlying tremor components in essential tremor and Parkinson's disease
    John A Burne
    School of Biomedical Sciences, University of Sydney, P O Box 170, Lidcombe, New South Wales, 1825, Australia
    Muscle Nerve 30:347-55. 2004
    ..peak amplitude against the applied loads estimated the magnitudes of the load-dependent (LDT) and load-independent (LIT) tremor components. The amplitude of ET was linearly related to increase in gravitational load...
  47. ncbi Connecting thermodynamics and economics: well-lit roads and burned bridges
    Mark David Glucina
    Department of Mechanical Engineering, Graduate School of Advanced Technology and Science, The University of Tokushima, Tokushima, Japan
    Ann N Y Acad Sci 1185:11-29. 2010
    ..But it does not provide a prescription outside of this technical realm. Factors, such as environmental impact, cost, and social acceptability, will ultimately determine which technically feasible options are most desirable...
  48. ncbi Acaricidal activity of extracts from Petiveria alliacea (Phytolaccaceae) against the cattle tick, Rhipicephalus (Boophilus) microplus (Acari: ixodidae)
    J A Rosado-Aguilar
    Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autonoma de Yucatan, Km 15 5 carretera Mérida Xmatkuil, Yucatan, Mexico
    Vet Parasitol 168:299-303. 2010
    ..out on larvae and adults of the cattle tick Rhipicephalus (Boophilus) microplus using the larval immersion test (LIT) and adult immersion test (AIT), respectively. Methanolic extracts of stems and leaves of P...
  49. ncbi Identification of free radicals by spin trapping with DEPMPO and MCPIO using tandem mass spectrometry
    Ana Reis
    Mass Spectrometry Center, Department of Chemistry, University of Aveiro, 3810 193 Aveiro, Portugal
    Eur J Mass Spectrom (Chichester, Eng) 15:689-703. 2009
    ..The hydroxyl and biomolecule free radical adducts were detected using a QTOF and a linear ion trap (LIT) mass spectrometers...
  50. ncbi Low intensity training decreases markers of oxidative stress in skeletal muscle of mdx mice
    Jan J Kaczor
    Department of Pediatrics, McMaster University Medical Center, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5
    Free Radic Biol Med 43:145-54. 2007
    ..exercise clearly induces muscle damage in mdx mice; however, the effects of low intensity exercise training (LIT) on mdx muscle are less clear...
  51. ncbi Alterations in xenobiotic metabolism in the long-lived Little mice
    Daniel Amador-Noguez
    Molecular and Human Genetics Department, Baylor College of Medicine, Houston, TX 77030, USA
    Aging Cell 6:453-70. 2007
    Our previous microarray expression analysis of the long-lived Little mice (Ghrhr(lit/lit)) showed a concerted up-regulation of xenobiotic detoxification genes...
  52. ncbi A systematic review of the quality of research on hands-on and distance healing: clinical and laboratory studies
    Cindy C Crawford
    Samueli Institute for Information Biology, Alexandria, VA, USA
    Altern Ther Health Med 9:A96-104. 2003
    ..To systematically review the quality of published experimental clinical and laboratory research involving hands-on healing and distance healing between 1955 and 2001...
  53. ncbi Participation of ovarian 20 alpha-hydroxysteroid dehydrogenase in luteotrophic and luteolytic processes during rat pseudopregnancy
    J Matsuda
    Department of Veterinary Physiology, Faculty of Agriculture, University of Tokyo, Japan
    J Reprod Fertil 88:467-74. 1990
    ..When ovulation was blocked for more than 2 weeks by placing rats in a continuously lit environment before the induction of pseudopregnancy, only minimal levels of 20 alpha-HSD activity were detectable ..
  54. ncbi Insecticidal toxins from black widow spider venom
    A Rohou
    Division of Cell and Molecular Biology, Imperial College London, Exhibition Road, London, SW7 2AZ, UK
    Toxicon 49:531-49. 2007
    ..All LTXs whose structures have been elucidated (alpha-LIT, delta-LIT, alpha-LTX and alpha-LCT) are highly homologous and have a similar domain architecture, which consists ..
  55. ncbi Translation elongation factor Tu cleaved by a phage-exclusion system
    Y T Yu
    Department of Microbiology, Michigan State University, East Lansing 48824 1101
    Proc Natl Acad Sci U S A 91:802-6. 1994
    ..T4 multiples poorly in Escherichia coli strains carrying the defective prophage, e14; the e14 prophage contains the lit gene for late inhibitor of T4 in E. coli...
  56. ncbi Interactive effects of CO2 and O3 on a ponderosa pine plant/litter/soil mesocosm
    D M Olszyk
    US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Corvallis, OR 97333, USA
    Environ Pollut 115:447-62. 2001
    ..seedling/soil/litter system was initiated in April 1998. The experiment was conducted in outdoor, sun-lit chambers where aboveground and belowground ecological processes could be studied in detail...
  57. ncbi Application of high-performance liquid chromatography-tandem mass spectrometry with a quadrupole/linear ion trap instrument for the analysis of pesticide residues in olive oil
    M D Hernando
    Department of Analytical Chemistry, University of Almeria, 04120 Almeria, Spain
    Anal Bioanal Chem 389:1815-31. 2007
    ..The LC-MS method was developed using a hybrid quadrupole/linear ion trap (QqQ(LIT)) analyzer...
  58. ncbi Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity
    Guillaume Dorothee
    Laboratoire Cytokines et Immunologie des Tumeurs Humaines, Institut National de la Santé et de la Recherche Médicale Unité 487, Institut Gustave Roussy, Villejuif, France
    J Immunol 169:809-17. 2002
    ..lung carcinoma cell lines, we first showed that most of them expressed TRAIL-R1/DR4, TRAIL-R2/DR5, but not TRAIL-R3/DcR1 and TRAIL-R4/DcR2, and were susceptible to APO2L/TRAIL-induced cell death...
  59. ncbi [Informing patients in otorhinolaryngology: legislation, jurisprudence, and incidences in practice]
    C Manaouil
    Consultation de médecine légale, CHU Nord Amiens, Place Victor Pauchet, 80054 Amiens cedex 01, France
    Ann Otolaryngol Chir Cervicofac 124:1-8. 2007
    ..is justified by the respect for the autonomy of the patient and by the necessity of obtaining a free and lit assent. Information is not only a preliminary to the medical act; it has to be done before, during and after...
  60. ncbi SSR181507, a putative atypical antipsychotic with dopamine D2 antagonist and 5-HT1A agonist activities: improvement of social interaction deficits induced by phencyclidine in rats
    D Boulay
    CNS Department, Sanofi Synthelabo Recherche, Discovery Research, 31 Ave P Vaillant Couturier, 92220 Bagneux, France
    Neuropharmacology 46:1121-9. 2004
    ..Pairs of unfamiliar rats were placed for 10 min each day into a dimly lit arena, during four consecutive days. On the test day (5th day), each pair was placed into the arena 30 min after i...
  61. ncbi Food contaminant analysis at ultra-high mass resolution: application of hybrid linear ion trap - orbitrap mass spectrometry for the determination of the polyether toxins, azaspiracids, in shellfish
    Zuzana Skrabáková
    PROTEOBIO Mass Spectrometry Centre, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Rapid Commun Mass Spectrom 24:2966-74. 2010
    ..An LTQ Orbitrap mass spectrometer is a hybrid instrument that combines linear ion trap (LIT) mass spectrometry (MS) with high-resolution Fourier transform (FT) MS and this was exploited to perform ..
  62. ncbi [Correlation between adolescents psychical disorders and their difficulties of psychosocial adaptation]
    Aurelija Markeviciūte
    Psychiatry Department, Kaunas University of Medicine Hospital, Kaunas, Lithuania
    Medicina (Kaunas) 43:647-56. 2007
    ..To study the correlation between adolescents' psychical disorders and their difficulties of psychosocial adaptation...
  63. ncbi Two- and 4-hour bright-light exposures differentially effect sleepiness and performance the subsequent night
    V C Thessing
    Sleep Disorders and Research Center, Deaconess Medical Center, St. Louis, MO 63139
    Sleep 17:140-5. 1994
    ..Following light exposure, subjects remained awake until 0800 hours in a dimly lit room and slept in the laboratory between 0800 and 1600 hours, during which time sleep was estimated with actigraphy...
  64. ncbi Repression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but not its receptors during oral cancer progression
    Nadarajah Vigneswaran
    Department of Diagnostic Sciences, The University of Texas Health Science Center at Houston, Dental Branch, Houston, Texas 77030, USA
    BMC Cancer 7:108. 2007
    ..TRAIL binds to two cell-death-inducing (DR4 and DR5) and two decoy (DcR1, and DcR2) receptors...
  65. ncbi Polymorphisms in TRAIL receptor genes and risk of breast cancer in Spanish women
    José I Martínez-Ferrandis
    Laboratorio de Genetica Molecular, Centro de Investigacion Principe Felipe, Valencia, Spain
    Cancer Biomark 3:89-93. 2007
    ..TRAIL binds to the proapoptotic death receptor DR4 and DR5 as well as to the decoy receptors DcR1 and DcR2...
  66. ncbi Changes of bone turnover markers after marathon running over 245 km
    G Mouzopoulos
    Department of Orthopaedics, Evangelismos, Athens, Greece
    Int J Sports Med 28:576-9. 2007
    ..Osteocalcin levels were significantly decreased from 4.6 microg/lit to 3.8 microg/lit (p < 0.05). Activity of b-ALP was significantly decreased from 66 U/lit to 61...
  67. ncbi Thrombolysis in cervical artery dissection
    Dimitrios Georgiadis
    Department of Neurology, University of Zurich, Zurich, Switzerland
    Front Neurol Neurosci 20:140-6. 2005
    Safety and efficacy of intravenous (IVT) and intra-arterial thrombolysis (LIT) in patients with acute stroke due to spontaneous cervical artery dissection were not assessed in any controlled randomized trial...
  68. ncbi Opposing activities of LIT-1/NLK and DAF-6/patched-related direct sensory compartment morphogenesis in C. elegans
    Grigorios Oikonomou
    Laboratory of Developmental Genetics, The Rockefeller University, New York, New York, United States of America
    PLoS Biol 9:e1001121. 2011
    ..From a genetic screen, we found that mutations in the gene lit-1/Nemo-like kinase (NLK) suppress daf-6...
  69. ncbi 'N-in-one' strategy for metabolite identification using a liquid chromatography/hybrid triple quadrupole linear ion trap instrument using multiple dependent product ion scans triggered with full mass scan
    Austin C Li
    Covance Laboratories Inc, 3301 Kinsman Boulevard, Madison, Wisconsin, USA
    Rapid Commun Mass Spectrom 21:1421-30. 2007
    ..describes a new strategy that utilizes the fast trap mode scan of the hybrid triple quadrupole linear ion trap (QqQ(LIT)) for the identification of drug metabolites...
  70. ncbi Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro- and nano-CT
    Philipp Schneider
    Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland
    J Bone Miner Res 22:1557-70. 2007
    ..Results in two different mouse strains, C57BL/6J-Ghrhr(lit)/J and C3...
  71. ncbi Dim nighttime illumination interacts with parametric effects of bright light to increase the stability of circadian rhythm bifurcation in hamsters
    Jennifer A Evans
    Department of Psychology, University of California, San Diego, La Jolla, California, USA
    Chronobiol Int 28:488-96. 2011
    ..of component oscillators that comprise the circadian system and is facilitated when daily scotophases are dimly lit rather than completely dark...
  72. ncbi Prevalence of behaviors related to cigarette-caused fires: a survey of Ontario smokers
    R J O'Connor
    Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Inj Prev 13:237-42. 2007
    ..To identify the prevalence and correlates of behaviors related to the risk of cigarette-caused fires...
  73. ncbi The expression of TRAIL and its receptors in gastric cancer and the apoptotic effect of rh-TRAIL on SGC7901 cells
    Jian Kun Hu
    Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P R China
    Oncol Rep 21:681-8. 2009
    ..The expression of TRAIL, DR4 and DcR1 were studied in 34 cases of human gastric cancer tissues and 15 cases of adjacent normal mucosa tissues, as well as ..
  74. ncbi Determination of the susceptibility of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) to ivermectin and fipronil by Larval Immersion Test (LIT) in Uruguay
    E Castro-Janer
    Department of Parasitology, School of Veterinary Medicine, UDELAR, Uruguay
    Vet Parasitol 178:148-55. 2011
    ..tick strains from different Uruguayan counties to ivermectin (IVM) and fipronil by using the Larval Immersion Test (LIT). The Mozo strain was used as the susceptible reference strain...
  75. ncbi Toward total structural analysis of cardiolipins: multiple-stage linear ion-trap mass spectrometry on the [M - 2H + 3Li]+ ions
    Fong Fu Hsu
    Mass Spectrometry Resource, Division of Endocrinology, Diabetes, Metabolism, and Lipid Research, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Am Soc Mass Spectrom 21:1863-9. 2010
    ESI multiple-stage linear ion-trap (LIT) mass spectrometric approaches for a near-complete structural characterization of cardiolipins (CLs), including identification of the fatty acyl substituents, assignment of the fatty acid ..
  76. ncbi Likelihood of inadequate treatment: a novel approach to evaluating drug-resistance patterns
    Heinz Burgmann
    Division of Intensive Care, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria
    Infect Control Hosp Epidemiol 30:672-7. 2009
    ..To provide a novel way to predict the likelihood that antibiotic therapy will result in prompt, adequate therapy on the basis of local microbiological data...
  77. ncbi Mass-selective axial ejection from a linear ion trap with a direct current extraction field
    Masuyuki Sugiyama
    Central Research Laboratory, Hitachi, Ltd, Tokyo, Japan
    Rapid Commun Mass Spectrom 23:2917-22. 2009
    We have developed a new mass-selective axial ejection method from a linear ion trap (LIT)...
  78. ncbi Standard examination system for laparoscopy in penetrating abdominal trauma
    Nilton Tokio Kawahara
    Laboratory of Surgical Pathophysiology Investigation Lim 62, Department of Trauma, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Trauma 67:589-95. 2009
    The high missed occult small bowel injuries (SBI) associated with laparoscopy in trauma (LIT) is a major reason why some surgeons still preclude LIT today...
  79. ncbi Climbing plants in a temperate rainforest understorey: searching for high light or coping with deep shade?
    Fernando Valladares
    Instituto de Recursos Naturales, Centro de Ciencias Medioambientales, CSIC, E 28006, Madrid, Spain
    Ann Bot 108:231-9. 2011
    While the climbing habit allows vines to reach well-lit canopy areas with a minimum investment in support biomass, many of them have to survive under the dim understorey light during certain stages of their life cycle...
  80. ncbi Particle-packed column versus silica-based monolithic column for liquid chromatography-electrospray-linear ion trap-tandem mass spectrometry multiallergen trace analysis in foods
    Chiara Bignardi
    Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica, Universita degli Studi di Parma, Viale G P Usberti 17 a, I 43100 Parma, Italy
    J Chromatogr A 1217:7579-85. 2010
    ..in cereals and biscuits using liquid chromatography-electrospray-linear ion trap-tandem mass spectrometry (LC-ESI-LIT-MS(2)) was developed and validated...
  81. ncbi Cell-surface CD200 may predict efficacy of paternal mononuclear leukocyte immunotherapy in treatment of human recurrent pregnancy loss
    David A Clark
    Department of Medicine, Molecular Medicine and Pathology, Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada
    Am J Reprod Immunol 61:75-84. 2009
    ..unexplained recurrent pregnancy loss appears to benefit from transfusion of allogeneic paternal blood leukocytes (LIT), and considerable effort has been devoted to characterizing those who may benefit...
  82. ncbi Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer
    Erin E Bessette
    Division of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, Albany, New York 12201, USA
    Anal Chem 81:809-19. 2009
    A two-dimensional linear quadrupole ion trap mass spectrometer (LIT/MS) was employed to simultaneously screen for DNA adducts of environmental, dietary, and endogenous genotoxicants, by data-dependent constant neutral loss scanning ..
  83. ncbi CID of singly charged antioxidants applied in lubricants by means of a 3D ion trap and a linear ion trap-Orbitrap mass spectrometer
    Alexander Kassler
    Research Division Instrumental Analytical Chemistry, Institute of Chemical Technologies and Analytics, Vienna University of Technology, Austria
    J Mass Spectrom 46:517-28. 2011
    ..by two different types of ion trap mass spectrometers: a three-dimensional ion trap (3D-IT) and a linear IT (LIT) Orbitrap MS...
  84. ncbi Transcriptional regulation of mouse alpha A-crystallin gene in a 148kb Cryaa BAC and its derivates
    Louise Wolf
    The Departments of Ophthalmology and Visual Sciences, Bronx, NY 10461, USA
    BMC Dev Biol 8:88. 2008
    ..Previously, we identified two novel distal control regions, DCR1 and DCR3...
  85. ncbi [Functional mRNA expression analysis and classification of colonic biopsy samples using overall cDNA microarray technique]
    Orsolya Galamb
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 149:219-32. 2008
    ....
  86. ncbi Episcleritis as a possible complication of lymphocyte immunotherapy--case report
    B Katsoff
    The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Camden, NJ, USA
    Clin Exp Obstet Gynecol 34:247-9. 2007
    Recurrent episceleritis is uncommon. Lymphocyte immunotherapy (LIT) is frequently useful in establishing successful pregnancies in women with previously failed in vitro fertilization (IVF) cycles.
  87. ncbi Pulmonary vascular compliance and pleural effusion duration after the Fontan procedure
    Tae Jin Yun
    Division of Pediatric Cardiac Surgery, Asan Medical Center, University of Ulsan, Republic of Korea
    Int J Cardiol 133:55-61. 2009
    ..We hypothesized that low pulmonary vascular compliance (PVC) is a risk factor for persistent pleural effusion after the Fontan operation...
  88. ncbi Decoy receptor 3: a pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases and cancer
    Wan Wan Lin
    Department of Pharmacology, National Taiwan University, Taipei, Taiwan
    Biochem Pharmacol 81:838-47. 2011
    ..molecules belonging to tumor necrosis factor receptor superfamily (TNFRSF) have been identified, including decoy receptor 1 (DcR1), decoy receptor 2 (DcR2), and decoy receptor 3 (DcR3)...
  89. ncbi TRAIL upregulates decoy receptor 1 and mediates resistance to apoptosis in insulin-secreting INS-1 cells
    Soojeong Kang
    Department of Pharmacology, Dong A University College of Medicine, Medical Science Research Center, Busan 602 714, Republic of Korea
    Biochem Biophys Res Commun 396:731-5. 2010
    ..related receptors bind TRAIL: two death receptors (DR4 and DR5) that promote apoptosis, and two decoy receptors (DcR1 and DcR2) that act as dominant-negative inhibitors of TRAIL-mediated apoptosis...
  90. ncbi Myosin light chain is a novel shrimp allergen, Lit v 3
    Rosalia Ayuso
    Division of Allergy and Immunology and the Jaffe Food Allergy Research Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Allergy Clin Immunol 122:795-802. 2008
    ..Shellfish allergy is a prevalent, long-lasting disorder usually persisting throughout life. Few options are available for treatment, and avoidance is the only therapy recommended...
  91. ncbi Stereoscopic perception of real depths at large distances
    Stephen Palmisano
    School of Psychology, University of Wollongong, Wollongong, Australia
    J Vis 10:19. 2010
    ..Pairs of Light Emitting Diode (LED) targets were presented either in complete darkness or with the environment lit as far as the nearest LED (the observation distance)...
  92. ncbi The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility
    J M Bugni
    McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, 1400 University Avenue, Madison, WI 53706, USA
    Carcinogenesis 22:1853-62. 2001
    ..both males and females, wild-type mice developed significantly more tumors than growth hormone-deficient, C57BL/6J-lit/lit (B6-lit/lit) mutant mice following perinatal treatment with the carcinogen N,N-diethylnitrosamine (DEN)...
  93. ncbi Characterization of two receptors for TRAIL
    P Schneider
    Institute of Biochemistry, University of Lausanne, Epalinges, Switzerland
    FEBS Lett 416:329-34. 1997
    ..All three TRAIL receptors bind TRAIL with similar affinity, suggesting a complex regulation of TRAIL-mediated signals...
  94. ncbi Simple and conditional visual discrimination with wheel running as reinforcement in rats
    I H Iversen
    Department of Psychology, University of North Florida, Jacksonville, 32224, USA
    J Exp Anal Behav 70:103-21. 1998
    ..In Experiment 1, 2 rats learned to press a lit key to produce access to running; responding was virtually absent when the key was dark, but latencies to respond ..
  95. ncbi Improved mobility and independence of night-blind people using night-vision goggles
    Dyonne T Hartong
    Laboratory of Experimental Ophthalmology, School of Behavioral and Cognitive Neurosciences, University of Groningen, The Netherlands
    Invest Ophthalmol Vis Sci 45:1725-31. 2004
    ..To investigate whether the use of night-vision goggles (NVGs) by night-blind people improves their mobility and sense of independence under dark circumstances...
  96. ncbi The major head protein of bacteriophage T4 binds specifically to elongation factor Tu
    R Bingham
    School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom
    J Biol Chem 275:23219-26. 2000
    The Lit protease in Escherichia coli K-12 strains induces cell death in response to bacteriophage T4 infection by cleaving translation elongation factor (EF) Tu and shutting down translation...
  97. ncbi Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist
    Keiji Iida
    Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Endocrinology 145:1564-70. 2004
    ..gland and compared the levels with those derived from liver of bovine GH transgenic, GH antagonist transgenic, lit/lit mice, and their respective controls using real-time RT-PCR...
  98. ncbi Regulation of translation of the head protein of T4 bacteriophage by specific binding of EF-Tu to a leader sequence
    Larry Snyder
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824 4320, USA
    J Mol Biol 334:349-61. 2003
    ..This binding was discovered because EF-Tu bound to Gol peptide is the specific substrate of the Lit protease that cleaves the EF-Tu between amino acid residues Gly59 and lle60, blocking phage development...
  99. ncbi NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats
    S E File
    Psychopharmacology Research Unit, Centre for Neuroscience, GKT School of Biomedical Sciences, King s College London, UK
    Psychopharmacology (Berl) 152:105-9. 2000
    ..Evidence is starting to accumulate that NK1 receptor antagonists might have anxiolytic effects in animal tests and in patients...
  100. ncbi RNA interference is required for normal centromere function in fission yeast
    Tom Volpe
    Cold Spring Harbor Laboratory, Bungtown Road, New York 11724, USA
    Chromosome Res 11:137-46. 2003
    ..We show that the RNAi components, Argonaute (Ago1), Dicer (Dcr1) and RNA-dependent RNA polymerase (Rdp1), are required to maintain silencing, lysine 9 methylation of histone H3 ..
  101. ncbi TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction
    D Ou
    Department of Pediatrics, University of British Columbia, Canada
    Diabetologia 45:1678-88. 2002
    ..The aim of this study is to investigate whether apoptosis in human beta cells can be related to the induction of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway...

Research Grants63

  1. Impact of Antibiotics and Vaccines on the in vivo Evolution of S. pneumoniae
    Garth Ehrlich; Fiscal Year: 2009
    ..o. LI______________-'1 I I~_ddAltt\.eki!lit\JAIMi'\S~eA",tjW.~t1r~1lli~l~""Rhl)1e.~iII TotalSenior/Key Person bP766,,733...
  2. Waterpipe tobacco smoke: toxicant exposure and effects
    Thomas Eissenberg; Fiscal Year: 2009
    ..the "head" with sweetened and flavored tobacco, covers it with perforated aluminum foil, and tops the foil with lit charcoal. Charcoal and tobacco smoke pass to the user via a half-filled water bowl, hose, and mouthpiece...
  3. Waterpipe tobacco smoke: toxicant exposure and effects
    THOMAS EVAN EISSENBERG; Fiscal Year: 2010
    ..the "head" with sweetened and flavored tobacco, covers it with perforated aluminum foil, and tops the foil with lit charcoal. Charcoal and tobacco smoke pass to the user via a half-filled water bowl, hose, and mouthpiece...
  4. Self-report and behavioral reactivity to combined smoking cues
    Cynthia A Conklin; Fiscal Year: 2010
    ..Two key reasons for this limitation include: (1) focusing primarily on proximal smoking cues (e.g., lit cigarettes, pictorial stimuli of smoking) while ignoring distal cues those less contiguous to the act of smoking (e...
  5. Self-report and behavioral reactivity to combined smoking cues
    Cynthia Conklin; Fiscal Year: 2009
    ..Two key reasons for this limitation include: (1) focusing primarily on proximal smoking cues (e.g., lit cigarettes, pictorial stimuli of smoking) while ignoring distal cues those less contiguous to the act of smoking (e...
  6. TRAIL receptor in apoptosis and the immune system
    Astar Winoto; Fiscal Year: 2005
    ..Several TRAIL receptors have been identified in human. These include DR4, DR5, DcR1 and DcR2...
  7. Determinates of anti-HIV nucleic acid aptamer potency and resistance
    Donald Burke; Fiscal Year: 2009
    ..pdfMime Type: application/pdf 8. Bibliography & References Cited 5133-LIT-CITED_NIH07fRT-Aptamers.pdMf ime Type: application/pdf 9...
  8. Transgenic Approaches to Evaluate IGF-I Role in Peak BMD
    Subburaman Mohan; Fiscal Year: 2010
    ..To establish that TH regulates IGF-I expression independent of GH, we will use GH-deficient lit/lit mouse model with a mutation in GH-releasing hormone receptor...
  9. Role of Regulatory CD8 T Cells in Murine Asthma
    Roger S Thrall; Fiscal Year: 2010
    ..which with chronic OVA exposure results in resolution of AAD and the development of local inhalational tolerance (LIT)...
  10. HLTH LIT, SOC SUPPORT,& HLTH: SURVEY OF MEDICARE ENROLLE
    Shoou Yih Lee; Fiscal Year: 2003
    ..abstract_text> ..
  11. GENETIC REGULATION OF IGF I IN PEAK ONE DENSITY OF MICE
    Clifford Rosen; Fiscal Year: 2000
    ..on bone mass in the absence of GH regulation, we have developed C3H and B6 strains carrying the mutant gene little (lit) that result in genetic deficiency in serum GH...
  12. Novel Thrombectomy Catheter for Ischemic Stroke
    GUIREN WANG; Fiscal Year: 2004
    ..b>liT Chicago) and a commercial manufacturer of catheters (Spire Biomedical, MA)...
  13. HORMONAL REGULATION OF BILE FLOW
    Francis Simon; Fiscal Year: 1999
    ..Hormone replacement studies will be conducted in hypophysectomized rats and genetically deficient mice (lit/lit)...
  14. Transcriptional Regulation by the Wnt Effector POP-1
    Rueyling Lin; Fiscal Year: 2011
    ..The overall objective of this proposal is to understand how phosphorylation by the MAP kinase complex, LIT-1/WRM-1, affects POP-1 activity, how POP-1 sequence itself influence its phosphorylation by LIT-1/WRM-1, and how ..
  15. Transcriptional Regulation by the Wnt Effector POP-1
    Rueyling Lin; Fiscal Year: 2010
    ..The overall objective of this proposal is to understand how phosphorylation by the MAP kinase complex, LIT-1/WRM-1, affects POP-1 activity, how POP-1 sequence itself influence its phosphorylation by LIT-1/WRM-1, and how ..
  16. Developmental Regulation of Drug Processing Genes
    Xiao bo Zhong; Fiscal Year: 2010
    ..GH in determining ontogenic hepatic expression of drug processing genes in HNF11-null, FXR-null, and GH deficiency (lit/lit) mice using the same working strategy...
  17. Cellular Mechanisms of PTLD in Transplant Resipients
    OLIVIA MARTINEZ; Fiscal Year: 2006
    ..The role of the decoy receptors DcR1 and DcR2 in resistance to TRAIL cytotoxicity will be examined...
  18. Role of IGF-1 in Modulation of Longevity
    Christian Sell; Fiscal Year: 2007
    ..ability to compare and contrast different aspects of the phenotype of the Igfl hypomorphs with the Snell, Ames and lit/lit mouse models will give important insight into those aspects of the phenotypethat are important to longevity...
  19. Role of IGF-1 in Modulation of Longevity
    Christian Sell; Fiscal Year: 2007
    ..ability to compare and contrast different aspects of the phenotype of the Igfl hypomorphs with the Snell, Ames and lit/lit mouse models will give important insight into those aspects of the phenotype that are important to longevity...
  20. Cellular Mechanisms of PTLD in Transplant Resipients
    OLIVIA MARTINEZ; Fiscal Year: 2007
    ..The role of the decoy receptors DcR1 and DcR2 in resistance to TRAIL cytotoxicity will be examined...
  21. Role of IGF-1 in Modulation of Longevity
    Christian Sell; Fiscal Year: 2009
    ..ability to compare and contrast different aspects of the phenotype of the Igfl hypomorphs with the Snell, Ames and lit/lit mouse models will give important insight into those aspects of the phenotype that are important to longevity...
  22. MOLECULAR BASIS OF SNELL DWARF AND LITTLE LONGEVITY
    John Papaconstantinou; Fiscal Year: 2003
    ..The mouse dwarf mutants Snell (dw/dw), Ames (df/df) and little (lit/lit), live significantly longer than their normal siblings. The nature of the dwarf mutations, i.e...
  23. Regulation of breast cancer growth by activation peptide
    Vaclav Vetvicka; Fiscal Year: 2006
    ..For Aim lit is hypothesized that the overproduction of procathepsin D results in an increase in the metastatic potential of ..