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Genomes and Genes | PDAP1SummaryGene Symbol: PDAP1 Description: PDGFA associated protein 1 Alias: HASPP28, PAP, PAP1, 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein Species: human Top Publications
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Publications
[Influence of pulmonary hemodynamics on right ventricular ejection fraction in chronic obstructive pulmonary disease]S Steiner
, , Pneumologie und Angiologie
Pneumologie 53:249-54. 1999..Right ventricular function might be influenced by the afterload, which depends on pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR)...
Ambulatory health services provided to low-income and homeless adult patients in a major community health centerL Gelberg
UCLA School of Medicine, Division of Family Medicine, Los Angeles 90095-1683, USA
J Gen Intern Med 11:156-62. 1996..Preventive health services such as tuberculosis skin tests, sexually transmitted disease (STD) screening, and Pap tests were provided to both homeless and domiciled patients at low rates. CONCLUSIONS...
Are patients of women physicians screened more aggressively? A prospective study of physician gender and screeningM W Kreuter
Department of Community Health, School of Public Health, Saint Louis University, MO 63108, USA
J Gen Intern Med 10:119-25. 1995OBJECTIVE: To determine the effects of physician gender on rates of Pap testing, mammography, and cholesterol testing when identifying and adjusting for demographic, psychosocial, and other patient variables known to influence screening ..
[Characterization of structural and cellular components in pulmonary sarcoidosis granuloma]B Voss
, , Bochum
Pneumologie 50:303-10. 1996..Identification was subsequently performed either by means of indirect immunofluorescence or the PAP technique...
Cancer screening intervention among black women in inner-city Atlanta--design of a studyJ F Sung
Emory University School of Public Health, Atlanta, GA
Public Health Rep 107:381-8. 1992..Overall, about half of these volunteer subjects self-reported at least one Papanicolaou (Pap) smear and one breast examination within a year before enrollment in the study...
Physicians' utilization of health careT J Wachtel
Brown University School of Medicine, Providence, Rhode Island, USA
J Gen Intern Med 10:261-5. 1995..During the three-year period, 82% of the women physicians had received a Pap test, and 81% of the women physicians over the age of 40 years had received mammography...
The intersection of race, gender, and primary care: results from the Women Physicians' Health StudyG Corbie Smith
Department of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
J Natl Med Assoc 92:472-80. 2000..Force, we did find significant differences by ethnicity in compliance with clinical breast exams, mammograms, and pap smears. In conclusion, there continues to be fewer blacks and Hispanics in the U.S...
Usefulness of hybrid capture HPV DNA assay as a diagnostic tool for human papillomavirus infectionT Kubota
Department of Obstetrics and Gynecology, Juntendo University, Chiba, Japan
Kansenshogaku Zasshi 72:1219-24. 1998..The papanicolaou smear test (Pap smear) was carried out on all 234 women...
[Response of the coronary arteries to cold test and flow velocity increase is improved by deferoxamine but not by L-arginine in diabetic patients]A Nitenberg
Service de Physiologie et d'Explorations Fonctionnelles, INSERM U 426, , Colombes
Arch Mal Coeur Vaiss 90:1037-41. 1997..2 physiological tests, i.e. cold pressor test (CPT) and coronary flow-increase induced by 10 mg papaverine (PAP) injection in the distal left anterior descending CA (dLAD), were performed before (1) and after (2) either i.v...
Practice of early diagnosis of breast and uterine cervix cancer in a northern Italian townN Segnan
Area di Epidemiologia USSL Torino I, Italy
Tumori 76:227-33. 1990..where, currently, no kind of organized program exists and two projects of population screening programs, based on pap smear and mammography, have been developed. Fifty-two percent (95% confidence limits (C.L...
Cloning and chromosomal organization of a gene encoding a putative amino-acid permease from Saccharomyces cerevisiaeB Mai
, Martinsried, Germany
Gene 143:129-33. 1994..The sequence of the PAP1 (putative aa permease 1) gene contains an open reading frame of 566 aa corresponding to a polypeptide with a ..
Requiring physicians to respond to computerized reminders improves their compliance with preventive care protocolsD K Litzelman
Regenstrief Institute for Health Care, Department of Medicine, Indiana University School of Medicine, IN 46202
J Gen Intern Med 8:311-7. 1993..computer-generated reminders to perform fecal occult blood testing (FOBT), mammography, and cervical Papanicolaou (Pap) testing. DESIGN: Six-month prospective, randomized, controlled trial...
Effects of Phytolacca acinosa polysaccharides I with different schedules on its antitumor efficiency in tumor bearing mice and production of IL-1, IL-2, IL-6, TNF, CSF activity in normal miceH B Wang
Department of Pharmacology, College of Pharmacy, Second Military Medical University, Shanghai, P.R. China
Immunopharmacol Immunotoxicol 19:197-213. 1997Effects of Phytolacca acinosa polysaccharides I (PAP-I), 5 approximately 40 mg/kg in timing of 7 times/wk, 3 times/wk and 1 time/wk on their antitumor efficiency in Sarcoma-180 bearing mice were comparatively investigated...
Improvements in preventive care and communication for deaf patients: results of a novel primary health care programT G MacKinney
Medical College of Wisconsin, USA
J Gen Intern Med 10:133-7. 1995..The cases were more likely (p < 0.05) to report receiving within the preceding three years Pap tests (90% vs 72%), mammography (86% vs 53%), and rectal examinations (72% vs 25%), but not breast examinations (76%..
Chronic disease as a barrier to breast and cervical cancer screeningC I Kiefe
University of Alabama at Birmingham, Veterans Affairs Medical Center, 35205-4785, USA
J Gen Intern Med 13:357-65. 1998..mammogram, every 2 years for ages 50-74; for clinical breast examinations (CBEs), every year for all ages; and for Pap smears, every 3 years for ages under 65...
Atrial natriuretic peptide (ANP) in chronic obstructive pulmonary disease (COPD): the relationship between plasma ANP and lung function. Effects of exercise and of the calcium antagonist, isradipine, on plasma ANP. A randomised, double-blind, placebo-contN Graudal
Department of Pulmonary Medicine P/Chest Clinic, Bispebjerg Hospital, Copenhagen, Denmark
Horm Metab Res 24:130-3. 1992In patients with severe chronic obstructive pulmonary disease (COPD) an increased pulmonary arterial pressure (PAP), a raised plasma level of atrial natriuretic peptide (ANP) and a correlation between increasing PAP and increasing plasma ..
In-situ end labelling with bromodeoxyuridine--an advanced technique for the visualization of apoptotic cells in histological specimensA Aschoff
, , Germany
Horm Metab Res 28:311-4. 1996..Anti BrdU and the peroxidase anti peroxidase method (PAP) were used for staining the reaction product...
Acculturation and cervical cancer: knowledge, beliefs, and behaviors of Hispanic womenM P Harmon
AIDS Research Consortium of Atlanta, GA 30308, USA
Women Health 24:37-57. 1996..of Hispanic women, this study examines differences in relation to level of acculturation in knowledge about the Pap examination, fear/fatalism towards cancer, and cervical cancer screening behaviors...
Immunohistochemical characterization of rat central and peripheral nerve tumors induced by ethylnitrosoureaN R Raju
Department of Pathology, Michigan State University, East Lansing 48824
Toxicol Pathol 18:18-23. 1990..HNK-1) immunoreactivity utilizing the ABC method (avidin-biotin-complex) for GFAP, S-100 protein and NSE, and the PAP method (peroxidase-antiperoxidase) for Anti-Leu 7...
The ambulatory care of HIV-infected persons: a survey of physician practice patternsM D Stein
Division of General Internal Medicine, Rhode Island Hospital, Providence 02903
J Gen Intern Med 7:180-6. 1992..Greatest physician consensus was seen in the use of viral serologic testing, vaccinations, and Pap tests...
[Total anomalous pulmonary venous connection. Results of repair in 50 infants]J Ninet
Service de Chirurgie, , Lyon
Arch Mal Coeur Vaiss 83:217-21. 1990..5 Kg. The preoperative pulmonary to systemic pressure ratios (PAP/PS) enabled identification of two groups of patients: Group I: TAPVC without severe pulmonary hypertension (PAP/PS ..
Lithium toxicity in yeast is due to the inhibition of RNA processing enzymesB Dichtl
EMBL, Gene Expression Programme, Postfach 10 2209, 69012 Heidelberg, Germany
EMBO J 16:7184-95. 1997Hal2p is an enzyme that converts pAp (adenosine 3',5' bisphosphate), a product of sulfate assimilation, into 5' AMP and Pi...
Islet transplantation in experimental diabetes of the rat. XIII. Cryopreservation reduces MHC class II but not class I antigens of rat pancreatic isletsB K Flesch
3. Medizinische Klinik und Poliklinik, , Giessen, Germany
Horm Metab Res 23:1-6. 1991..onto rat pancreatic islets performing indirect immunofluorescence tests and peroxidase-anti-peroxidase staining (PAP). Three different freezing programs were used. Program A: 0...
Prostate adenocarcinoma using Gleason scores correlates with prostate-specific antigen and prostate acid phosphatase measurementsW J Shih
University of Kentucky Medical Center, Lexington
J Natl Med Assoc 84:1049-50. 1992..of prostate carcinoma and concurrent serum prostate-specific antigen (PSA) and prostate acid phosphatase (PAP) values, 65 men with prostate carcinoma were studied...
Serum tumour markers in human prostatic carcinoma. The value of a marker panel for prognostic informationP Ekman
Department of Urology, Karolinska Hospital, Stockholm, Sweden
Acta Oncol 30:173-5. 1991Serum from 102 patients was analysed with regard to its content of prostatic acid phosphatase (PAP), prostate specific antigen (PSA), neopterin, osteocalcin, thymidine kinase, C-reactive protein, and of tissue polypeptide antigen (TPA)...
Breast and cervical cancer screening among low-income women: impact of a simple centralized HMO interventionR E Hardy
Department of Medicine, Meharry Medical College, Nashville, TN 37208, USA
J Natl Med Assoc 88:381-4. 1996..While early detection methods (screening mammography, breast examinations, and pap smears) have proven to be effective means of decreasing these cancers, they are underused by all groups...
[Chronic respiratory failure in a case with juvenile-onset acid alpha-glucosidase deficiency; successful therapy with nasal intermittent positive pressure ventilation (NIPPV)]C Tanaka
Division of Child Neurology, Tottori University, Faculty of Medicine, Yonago
No To Hattatsu 29:51-4. 1997..He was treated with nocturnal NIPPV employing a device for delivering bilevel positive airway pressure (Bi-PAP). Nocturnal dyspnea and daytime somnolence rapidly disappeared with nocturnal ventilatory support...
Characteristics of women reporting cervical screeningF Parazzini
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Tumori 76:585-9. 1990..of cervical screening utilization decreased with age: regular screening (greater than or equal to 3 lifetime Pap smears) was reported by 46% of women aged 44 years or less, but only 11% of those aged 65 or more...
Knowledge, beliefs, attitudes, and cancer screening among inner-city African-American womenJ F Sung
Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
J Natl Med Assoc 89:405-11. 1997..Half of the subjects had an annual household income of < $15,000. About half had received a Pap smear and clinical breast examination within the year preceding the interviews...
Increasing breast and cervical cancer screening in low-income womenK L Margolis
Hennepin County Medical Center, University of Minnesota, Minneapolis 55404, USA
J Gen Intern Med 13:515-21. 1998..009), and the Pap smear rate was 70% in the intervention group versus 63% in the usual care group (p = .02)...
Low-cost technology for screening uterine cervical cancerA Parashari
Institute of Cytology and Preventive Oncology, New Delhi, India
Bull World Health Organ 78:964-7. 2000..b>Pap smears were obtained at the same time...
Screening for breast and cervical cancers: the importance of knowledge and perceived cancer survivabilityD N Pearlman
Department of Community Health, Brown University, Providence, RI 02912, USA
Women Health 28:93-112. 1999..Although national trends show that large percentages of women over age 50 are having mammograms and Pap tests, this progress is not likely to be sustained unless existing barriers are eliminated...
[Apropos of acute changes in left ventricular filling induced by antihypertensive treatment]M Dahan
, Paris
Arch Mal Coeur Vaiss 85:1079-83. 1992..An index of left atrial pressure was obtained by measuring the mean pulmonary arterial pressure (PAP)...
Rome women's screening study: knowledge, attitudes and practices of women regarding screening for breast and cervical cancerC A Perucci
Epidemiology Unit, Latium Regional Health Authority, Rome, Italy
Tumori 76:365-9. 1990..Seventy percent of the women had had at least one Pap smear. Women were classified as Pap smear underusers (26.0%), appropriate users (28.8%), and overusers (45...
Primary care and receipt of preventive servicesA B Bindman
Primary Care Research Center, San Francisco General Hospital, CA 94110, USA
J Gen Intern Med 11:269-76. 1996..care, regular place of care, and receipt of blood pressure screening, clinical breast examinations, mammograms, and Pap smears...
[Restoration of normal coronary vasomotricity after intravenous infusion of angiotensin converting-enzyme inhibitor (perindoprilat) in hypertensive patients]I Antony
Service d'Explorations Fonctionnelles, INSERM U251, , Colombes
Arch Mal Coeur Vaiss 88:1125-8. 1995..velocity in distal LAD have been measured at baseline, during CPT, during recontrol, and after 10 mg papaverine (PAP) injection in the mid portion of the LAD...
Clinic services for persons with AIDS. Experience in a high-prevalence stateL E Markson
Center for Research in Medical Education and Health Care, Jefferson Medical College, Philadelphia, PA, USA
J Gen Intern Med 12:141-9. 1997..001). General medicine/primary care clinics were less likely than community-based clinics to perform Pap smears (75% vs 94%) or to have case managers on payroll (21% vs 81%)...
Testing cervicography and cervicoscopy as screening tests for cervical cancerS Cecchini
Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
Tumori 79:22-5. 1993AIMS AND BACKGROUND: Suboptimal sensitivity is currently reported for Pap test in screening for cervical cancer...
Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytesGerhard J Nohynek
L OREAL Research and Development, Worldwide Safety Department, 25 29 quai Aulagnier, 92600 Asnières, France
Toxicol Lett 158:196-212. 2005We investigated the biotransformation of the oxidative arylamine (AA) hair dye ingredients [14C]-para-aminophenol (PAP) and [14C]-para-phenylenediamine (PPD) in reconstructed human epidermis and human hepatocytes...
Is language a barrier to the use of preventive services?S Woloshin
VA Outcomes Group, White River Junction, VT 05009, USA
J Gen Intern Med 12:472-7. 1997..language as the language spoken in the home and assessed self-reported receipt of breast examination, mammogram and Pap testing...
Significance of a first-time atypical Papanicolaou smear in a young, high-risk African-American and Latino-American populationG P Parham
Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock 72205
J Natl Med Assoc 86:273-7. 1994..The optimal management of first-time atypia on routine Pap smear has not been established...
Clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apneaClete A Kushida
Stanford University Center of Excellence for Sleep Disorders, 401 Quarry Road, Suite 3301, Stanford, CA 94305 5730, USA
J Clin Sleep Med 4:157-71. 2008Positive airway pressure (PAP) devices are used to treat patients with sleep related breathing disorders (SRBDs), including obstructive sleep apnea (OSA)...
Pulmonary alveolar proteinosis: a spectrum of cytologic, histochemical, and ultrastructural findings in bronchoalveolar lavage fluidS J Maygarden
Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7525, USA
Diagn Cytopathol 24:389-95. 2001Pulmonary alveolar proteinosis (PAP) is defined as abundant extracellular proteinaceous periodic acid-Schiff (PAS)-positive material which represents surfactant distending alveolar spaces...
Serum PSA and PAP measurements discriminating patients with prostate carcinoma from patients with nodular hyperplasiaW J Shih
Department of Veterans Affairs Medical Center, Lexington, Kentucky 40511
J Natl Med Assoc 86:667-70. 1994Prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) are the tumor markers for monitoring disease progression or improvement in patients with prostate adenocarcinoma...
Human papillomavirus (HPV) cervical lesions: results from 300 Italian women studied with DNA hybridization techniques and morphologyF Nuzzo
Dipartimento di Patologia, Osp. M. Bufalini, Cesena, Italia
Tumori 74:745-9. 1988..The prevalence of HPV cervical infection diagnosed by PAP smears was 11.6%...
Radioimmunodetection of prostate cancer by 111In-labeled monoclonal antibody against prostatic acid phosphataseA Ahonen
Department of Nuclear Medicine, Turku University Central Hospital, Finland
Acta Oncol 32:723-7. 1993Purified human prostate acid phosphatase (PAP) was used to generate a specific monoclonal antibody (FC 3001) for detection of PAP expressed by some prostatic carcinomas...
Role of Pap Test terminology and age in the detection of carcinoma invasive and carcinoma in situ in medically underserved California womenLydia P Howell
Department of Pathology, Davis School of Medicine, University of California, Davis, California, USA
Diagn Cytopathol 30:227-34. 2004Our goals were to evaluate Pap Test findings classified by the Bethesda system, and follow up biopsies from participants in the California Breast and Cervical Cancer Control Program (Ca-BCCCP) for: 1) correlation in the detection of ..
Attenuated hematopoietic response to granulocyte-macrophage colony-stimulating factor in patients with acquired pulmonary alveolar proteinosisJ F Seymour
Ludwig Institute for Cancer Research, Parkville, Australia
Blood 92:2657-67. 1998The pathogenesis of acquired pulmonary alveolar proteinosis (PAP), a rare lung disease characterized by excessive surfactant accumulation within the alveolar space, remains obscure...
Lack of correlation between para-aminophenol toxicity in vivo and in vitro in female Sprague-Dawley ratsR Shao
Department of Pharmacology and Toxicology, Philadelphia College of Pharmacy and Science, Pennsylvania 19104, USA
Fundam Appl Toxicol 31:268-78. 1996The present study was designed to test the hypothesis that para-aminophenol (PAP) nephrotoxicity is due to autooxidation...
Spontaneous screening for cervical cancer and diagnostic histories of incident casesL Bucchi
Cancer Prevention Centre, Ravenna, Italy
Tumori 78:239-43. 1992..the 5 years prior to diagnosis, 10/49 invasive cancer patients and 25/61 CIN III patients had had at least one pap smear reported as negative...
Physiological changes in rumen fermentation during acidosis induction and its control using a multivalent polyclonal antibody preparation in heifersM Blanch
Grup de Recerca en Nutrició, Maneig i Benestar Animal, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
J Anim Sci 87:1722-30. 2009..rumen fermentation during acidosis induction and its control using a multivalent polyclonal antibody preparation (PAP) were studied in a completely randomized experiment using 12 crossbred heifers (452 +/- 20 kg of BW)...
Effect of tamoxifen on endometrial histology, hormone receptors, and cervical cytology: a prospective study with follow-upKimberly K Leslie
Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM, USA
Appl Immunohistochem Mol Morphol 15:284-93. 2007..We aimed to evaluate the changes in histology in serial endometrial biopsies (Em bx), Papanicolaou smears (Pap smears), and endometrial ultrasounds as well as changes in the expression of ER, PRA, and PRB in response to ..
Implementation of cancer prevention guidelines in clinical practiceS J McPhee
Department of Medicine, University of California, San Francisco 94143-0320
J Gen Intern Med 5:S116-22. 1990..Preventive Services Task Force. Performance rates are consistently below published standards for all tests except Pap tests...
Trends in the prevalence of cervical intraepithelial neoplasia grade 3 in the district of Florence, ItalyS Cecchini
Centro per lo Studio e la Prevenzione Oncologica (CSPO, Florence, Italy
Tumori 81:330-3. 1995..STUDY DESIGN: We considered the women, recorded in the computerized archives of CSPO, who had had no pap test for at least 10 years...
High-grade cervical abnormalities and screening intervals in New South Wales, AustraliaSuzanne Schindeler
Department of Health NSW, North Sydney, Australia
J Med Screen 15:36-43. 2008..This study aims to determine the association of two versus three year screening intervals with the likelihood of detection of a high-grade cervical abnormality and cervical cancer...
Identifying women with cervical neoplasia: using human papillomavirus DNA testing for equivocal Papanicolaou resultsM M Manos
Division of Research, Northern California Kaiser Permanente Medical Group, Oakland 94611, USA
JAMA 281:1605-10. 1999A Papanicolaou (Pap) test result of atypical squamous cells of undetermined significance (ASCUS) presents a clinical challenge...
The role of the left ventricle in atrial natriuretic peptide secretion in acute mitral regurgitationK Satoh
Kitasato University School of Medicine, Kanagawa, Japan
Am J Hypertens 3:704-6. 1990..Left atrial pressure (LAP), right atrial pressure (RAP) and pulmonary artery pressure (PAP) increased significantly during MR, and decreased to the normal level after recovery from MR...
Factors predicting the persistence of genital human papillomavirus infections and PAP smear abnormality in HIV-positive and HIV-negative women during prospective follow-upM Branca
Unità di Citoistopatologia, Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanita, Viala Regina Elena 299, I 0061, Roma, Italy
Int J STD AIDS 14:417-25. 2003..and clearance of HPV infections (polymerase chain reaction [PCR] and sequencing) and cervical Papanicolaou (PAP) smear abnormalities, using both univariate (Kaplan-Meier) and multivariate (Cox) survival analysis...
Identification of the phosphatidic acid phosphatase type 2a isozyme as an androgen-regulated gene in the human prostatic adenocarcinoma cell line LNCaPW Ulrix
Laboratory for Experimental Medicine and Endocrinology, Faculty of Medicine, Onderwijs en Navorsing, Gasthuisberg, Catholic University of Leuven, Herestraat 49, B 3000 Leuven, Belgium
J Biol Chem 273:4660-5. 1998..b>PAP-2a; Kai., M., Wada, I., Imai, S.-i., Sakane, F., and Kanoh, H. (1997) J. Biol. Chem. 272, 24572-24578)...
Pulmonary vascular responses to surgical chemodenervation and chemical sympathectomy in dogsR Naeije
Department of Intensive Care, Erasme University Hospital, Brussels, Belgium
J Appl Physiol 66:42-50. 1989..and the peripheral chemoreceptor stimulant almitrine on multipoint pulmonary arterial pressure-cardiac index (PAP/Q) plots in 30 pentobarbital sodium-anesthetized dogs ventilated alternatively in hyperoxia [fraction of inspired ..
[The pulmonary expression of granulocyte-macrophage colony-stimulating factor and surfactant protein in adult idiopathic pulmonary alveolar proteinosis]Xian Mei Zhou
Department of Respiratory Medicine, Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
Zhonghua Nei Ke Za Zhi 44:832-5. 2005..beta chain (GM-CSFbetacR), surfactant protein (SP)-A and SP-D in adult patients with idiopathic pulmonary alveolar proteinosis (PAP), so as to demonstrate the possible association of GM-CSF, GM-CSFbetacR, SP-A and SP-D with human PAP.
Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphataseM Kai
Department of Biochemistry, Sapporo Medical University School of Medicine, West 17, South 1, Chuo Ku, Sapporo 060 Japan
J Biol Chem 271:18931-8. 1996We previously described the purification of an 83-kDa phosphatidic acid phosphatase (PAP) from the porcine thymus membranes (Kanoh, H., Imai, S.-i., Yamada, K. and Sakane, F.(1992) J. Biol. Chem. 267, 25309-25314)...
Cloning and characterization of two human isozymes of Mg2+-independent phosphatidic acid phosphataseM Kai
Department of Biochemistry, Sapporo Medical University School of Medicine, West 17, South 1, Chuo Ku, Sapporo 060, Japan
J Biol Chem 272:24572-8. 1997We obtained two human cDNA clones encoding phosphatidic acid phosphatase (PAP) isozymes named PAP-2a (Mr = 32,158) and -2b (Mr = 35, 119), both of which contained six putative transmembrane domains...
Relationship between the inhibition of phosphatidic acid phosphohydrolase-1 by oleate and oleoyl-CoA ester and its apparent translocationN Elabbadi
Laboratoire d Immunologie, Biochimie et Biologie moléculaire, Faculte des Sciences et Techniques, Universite Cadi Ayyad, B P 523 Beni Mellal, Morocco
Biochimie 87:437-43. 2005Phosphatidic acid phosphohydrolase-1 (PAP-1) activity is reversibly inhibited by fatty acids and their acyl-CoA esters and it appears paradoxical that these effectors have been reported to increase the liver's esterification capacity by ..
[Chlamydia trachomatis infection and bacterial analysis in pregnant women in II and III trimester of pregnancy]Agata Karowicz-Bilińiska
Klinika Patologii Ciazy I Katedry Ginekologii i Połoznictwa Uniwersytetu Medycznego w Lodzi
Ginekol Pol 78:787-91. 2007..It is the most common sexually transmitted disease. The infection may be the reason for PID and consequently even sterility. CT infection could be asymptomatic and the most frequently seen symptom is cervicitis in Pap smears.
Enantioseparation of 3-phenylacetylamino-2,6-piperidinedione and related chiral compoundsY Tang
Food and Drug Administration, Division of Drug Analysis, St. Louis, MO, USA
J Chromatogr A 752:93-9. 1996..HPLC methodology for the first successful enantiomeric separations of 3-phenylacetylamino-2,6-piperidinedione (PAP), a naturally occurring peptide derivative used for inhibiting the growth of cancer tissues...
Sleep laboratory study on single and repeated dose effects of paroxetine, alprazolam and their combination in healthy young volunteersManuel J Barbanoj
Centre d Investigacio de Medicaments, Institut de Recerca, Servei de Farmacologia Clinica, Hospital de la Santa Creu i Sant Pau, Barcelona, Espana
Neuropsychobiology 51:134-47. 2005....
Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in ratsH Zhang
Departments of Surgery and Pathology, State University of New York Health Science Center at Brooklyn, New York, NY 11203, USA
Scand J Gastroenterol 39:870-81. 2004Pancreatitis-associated protein (PAP) is a secretory protein not normally expressed in healthy pancreas but highly induced during acute pancreatitis...
A nurse practitioner intervention to increase breast and cervical cancer screening for poor, elderly black women. The Harlem Study TeamJ Mandelblatt
Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021
J Gen Intern Med 8:173-8. 1993..In the NP clinic, the annual rate of Pap tests increased to 56.9% from the baseline of 17.8%, and mammographies increased to 40% from 18.3%...
Abnormal Pap smears: a comparison of total abdominal hysterectomy and cone biopsy in managementH E Onah
Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Enugu, Nigeria
J Obstet Gynaecol 26:48-51. 2006..in Nigeria and that 91% of them will do either cone biopsy or hysterectomy for moderately or severely abnormal Pap smears. Currently, there are no local data to guide such patient care...
[The correlation of inflammation and epithelial changes in the Pap smears of cervix uteri]Marina Kos
Klinicki zavod za patologiju Ljudevit Jurak, Klinicka bolnica Sestre milosrdnice, Zagreb, Hrvatska
Acta Med Croatica 59:297-302. 2005..and type of cytologic abnormalities of uterine cervix classified according to Zagreb 1990, on routinely examined Pap smears during the 6-year period, and to investigate the connection of these abnormalities with lower genital tract ..
Longitudinal cytological follow-up of patients with a papanicolaou test interpretation of "atypical squamous cells of undetermined significance" that was followed by a negative reflex test for high-risk human papillomavirus typesRosemarie Rodriguez
Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX 78236, USA
Int J Gynecol Pathol 27:108-12. 2008The 2001 consensus guidelines essentially equated the follow-up management of patients with a Papanicolaou (Pap) test interpretation of negative for intraepithelial lesion or malignancy and those with an interpretation of atypical ..
Conventional Pap smear and liquid-based cytology as screening tools in low-resource settings in Latin America: experience of the Latin American screening studyAdhemar Longatto-Filho
Instituto Adolfo Lutz and Hospital Leonor M de Barros, Sao Paulo, Brazil
Acta Cytol 49:500-6. 2005To evaluate the performance of the conventional Pap test and liquid-based cytology (LBC) in an ongoing multicenter trial testing optional screening tools (cytology, screening colposcopy, visual inspection with acetic acid, visual ..
Pap tests of rural black womenJ A Sawyer
Department of Medicine, University of North Carolina, Chapel Hill
J Gen Intern Med 5:115-9. 1990Cervical cancer is an important cause of cancer mortality in black women. Pap tests may prevent such deaths, but poor, rural black women are relatively less likely than others to be screened...
Screening history of incident cases of invasive carcinoma of the cervix. Florence district 1988-1989S Ciatto
Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
Tumori 79:311-3. 1993..Non- or irregular attendance (negative smear-to-diagnosis interval > 5 years) for the Pap smear was recorded in 53 subjects...
A novel 1,25-dihydroxyvitamin D-activin A pathway in human alveolar macrophages is dysfunctional in patients with pulmonary alveolar proteinosis (PAP)Barbara P Barna
Division of Pulmonary and Critical Care Medicine, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Autoimmunity 42:56-62. 2009..proliferation, is severely deficient in alveolar macrophages from patients with pulmonary alveolar proteinosis (PAP), an autoimmune disorder characterized by surfactant accumulation and neutralizing autoantibodies to granulocyte-..
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphataseBrian M Olson
Department of Medicine, University of Wisconsin, Madison, WI 53792, USA
Cancer Immunol Immunother 59:943-53. 2010Prostatic acid phosphatase (PAP) has been investigated as the target of several antigen-specific anti-prostate tumor vaccines...
Is p16(INK4A) expression more useful than human papillomavirus test to determine the outcome of atypical squamous cells of undetermined significance-categorized Pap smear? A comparative analysis using abnormal cervical smears with follow-up biopsiesShin Nieh
Department of Pathology, School of Medicine, National Defense Medical Center and Tri Service General Hospital, No 325, Cheng Kung Road, Sec 2, Neihu 114, Taipei, Taiwan, Republic of China
Gynecol Oncol 97:35-40. 2005..HR-HPV) viral load to p16(INK4A) expression in atypical squamous cells of undetermined significance (ASCUS)-categorized Pap smears with follow-up biopsies in order to elucidate their relationships in gynecological pathology.
Costs to physician offices of providing medications to medically indigent patients via pharmaceutical manufacturer prescription assistance programsPatrick Clay
Kansas City University of Medicine and Biosciences, Dybedal Clinical Research Center, 1750 Independence Ave, Kansas City, MO 64106 1953, USA
J Manag Care Pharm 13:506-14. 2007..some PAPs require only 1 application whereas others require as many as 4 applications per year per drug per patient, depending on the manufacturer's requirements...
Toxicity, biological activity, and pharmacokinetics of TXU (anti-CD7)-pokeweed antiviral protein in chimpanzees and adult patients infected with human immunodeficiency virusF M Uckun
Biotherapy Program, Hughes Institute, St Paul, Minnesota 55113, USA
J Pharmacol Exp Ther 291:1301-7. 1999..the present study was to evaluate the toxicity and pharmacokinetics of TXU (anti-CD7)-pokeweed antiviral protein (PAP) in human immunodeficiency virus (HIV)-infected chimpanzees and adult patients...
Effects of the Bethesda System on the rate of unsatisfactory Pap smears in spontaneous cervical screeningN Morini
Department of Prevention, Ravenna Health Care District, Italy
Tumori 82:437-40. 1996..CONCLUSIONS: TBS led to a substantial change in the type of information provided by the cytology report (immediate effect). The monitoring program according to TBS led to a reduction in UNS attributable to sample taker (midterm effect)...
Profile of Pap smear cytology in the Western region of Saudi ArabiaAwatif Jamal
Department of Pathology, Faculty of Medicine, King Abdul Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia
Saudi Med J 24:1225-9. 2003..The aim of this study is to evaluate the abnormal cytological entities detected by cervical Pap smear in Western region of KSA and to discuss the importance of Pap smears screening programs.
Abilities of APTIMA, AMPLICOR, and ProbeTec assays to detect Chlamydia trachomatis and Neisseria gonorrhoeae in PreservCyt ThinPrep Liquid-based Pap samplesM Chernesky
St Joseph s Healthcare McMaster University, Toronto, Ontario, Canada
J Clin Microbiol 45:2355-8. 2007Infections with Chlamydia trachomatis and Neisseria gonorrhoeae are often asymptomatic. Liquid-based Pap (L-Pap) screening may provide samples for testing by commercial assays...
Plasma/blood pharmacokinetics and metabolism after dermal exposure to para-aminophenol or para-phenylenediamineWilliam E Dressler
Food Chem Toxicol 44:371-9. 2006The pharmacokinetics and metabolism following dermal application of [(14)C]-para-aminophenol (PAP) or [(14)C]-para-phenylenediamine (PPD) were investigated. Groups of rats were treated under occlusion for 24 h with 12...
Human papillomavirus and Papanicolaou tests to screen for cervical cancerPontus Naucler
Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
N Engl J Med 357:1589-97. 2007....
Attendance to a screening program for cervical cancer in the city of FlorenceS Ciatto
Centro Studio Prevenzione Oncologica, Firenze, Italy
Tumori 77:252-6. 1991..forty-one non-attenders according to computer-produced lists were interviewed: 29 were not evaluable, 148 had had a Pap test, 18 had not attended for valid reasons, and 146 were true refusers; 94 refusers accepted the interview as far ..
Adjuvant effect of water-soluble polysaccharide (PAP) from the mycelium of Polyporus albicans on the immune responses to ovalbumin in miceYongxu Sun
Department of Pharmacology, Qiqihar Medical University, Qiqihar 161042, China
Vaccine 26:3932-6. 2008In our previous work, a new water-soluble polysaccharide (PAP) from the mycelium of Polyporus albicans was identified for the first time...
The frequency of Pap smear screening in the United StatesBrenda E Sirovich
VA Outcomes Group 111B, Department of Veterans Affairs Medical Center, White River Junction, VT 50009, USA
J Gen Intern Med 19:243-50. 2004..health systems of all other industrialized nations recommend that most women need not undergo Papanicolaou (Pap) smear screening annually...
Elevated urinary levels and urothelial expression of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein in patients with interstitial cystitisTetsuya Makino
Department of Anatomy and Neurobiology, Osaka City University Graduate School of Medicine, Osaka, Japan Department of Urology, Osaka City University Graduate School of Medicine, Osaka, Japan
Urology 75:933-7. 2010..IC), we examined urinary levels and urothelial expression of human orthologue of pancreatitis-associated protein (PAP) III, namely, hepatocarcinoma-intestine-pancreas (HIP)/PAP, in patients with IC...
Is acid phosphatase (PAP) still justified in the management of prostatic cancer?M Kontturi
Department of Surgery, Oulu University Central Hospital, Finland
Acta Oncol 30:169-70. 1991The usefulness of acid phosphatase (PAP) and prostate specific antigen (PSA) is compared...
Placental anticoagulant proteins: isolation and comparative characterization four members of the lipocortin familyJ F Tait
Department of Biochemistry, University of Washington, Seattle 98195
Biochemistry 27:6268-76. 1988Previously we isolated and characterized a placental anticoagulant protein (PAP or PAP-I), which is a Ca2+-dependent phospholipid binding protein [Funakoshi et al...
Genomic clones encoding two isoforms of pokeweed antiviral protein in seeds (PAP-S1 and S2) and the N-glycosidase activities of their recombinant proteins on ribosomes and DNA in comparison with other isoformsEijiro Honjo
Department of Applied Biological Sciences, Saga University, Saga 840 8502, Japan
J Biochem 131:225-31. 2002..b>PAP-S is one of the isoforms found in seeds...
C-terminal deletion mutant of pokeweed antiviral protein inhibits viral infection but does not depurinate host ribosomesN E Tumer
Agricultural Biotechnology Center and Department of Plant Pathology, Rutgers University, Cook College, New Brunswick, NJ 08903 0231, USA
Proc Natl Acad Sci U S A 94:3866-71. 1997Pokeweed antiviral protein (PAP), a 29-kDa protein isolated from Phytolacca americana, inhibits translation by catalytically removing a specific adenine residue from the large rRNA of the 60S subunit of eukaryotic ribosomes...
SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intoleranceDavid N Douda
Lung Innate Immunity Research, Program in Physiology and Experimental Medicine, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
Orphanet J Rare Dis 4:29. 2009Pulmonary alveolar proteinosis (PAP) is a syndrome with multiple etiologies and is often deadly in lysinuric protein intolerance (LPI)...
An attempt to increase compliance to cervical cancer screening through general practitionersS Cecchini
Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
Tumori 75:615-8. 1989..The proportion of previous non responders who performed a Pap test after the campaign was 6.7%, the response being dependent on age (25-29 = 11.5%, 30-39 = 8.8%, 40-49 = 6...
Caffeine-resistance in fission yeast is caused by mutations in a single essential gene, crm1+K Kumada
Department of Biophysics, Faculty of Science, Kyoto University, Japan
Mol Gen Genet 250:59-68. 1996..ts crm1 mutant showed an abnormal chromosome structure at the restrictive temperature, an elevated expression of Pap1-dependent transcription, and cross-resistance to an unrelated drug such as staurosporine...
Coordinate regulation of secretory stress proteins (PSP/reg, PAP I, PAP II, and PAP III) in the rat exocrine pancreas during experimental acute pancreatitisR Graf
Pancreatitis Research Laboratory, Department of Visceral and Transplant Surgery, University Hospital, 8091 Zurich, Switzerland
J Surg Res 105:136-44. 2002..Pancreatitis-associated protein (PAP) belongs to the same family of proteins...
Detection of false-negative Pap smears using the PAPNET systemG M Troni
Department of Cytopathology, Center for Cancer Study and Prevention, Florence, Italy
Tumori 86:455-7. 2000..The study assessed the performance and the cost-outcome ratio of computer-assisted versus conventional manual Pap smear reading...
Histologic and clinical characteristics associated with rapidly progressive invasive cervical cancer: a preliminary report from the Yale Cancer Control Research UnitO Hadjimichael
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510
Yale J Biol Med 62:345-50. 1989..e., invasive cancer diagnosed within three years of a true negative Pap smear, is more likely to occur in younger women with high annual incomes (61 percent greater than $40,000) who ..
Clinical utility of adjunctive high-risk human papillomavirus DNA testing in women with Papanicolaou test findings of atypical glandular cellsChengquan Zhao
Department of Pathology, Magee Womens Hospital of University of Pittsburgh Medical Center, 300 Halket St, Pittsburgh, PA 15213, USA
Arch Pathol Lab Med 134:103-8. 2010Atypical glandular cell (AGC) Papanicolaou (Pap) test interpretations are challenging. Most biopsy findings are benign, but AGC results may also reflect highly significant noninvasive neoplastic and malignant histologic outcomes...
Research Grants
- SINGLE VISIT CERVICAL CANCER PREVENTION PROGRAMAlberto Manetta; Fiscal Year: 2002..the diagnosis and management of cervical cancer is the loss to follow-up for those who undergo screening using the Pap smear...
- ETIOLOGY AND NATURAL HISTORY OF CERVICAL NEOPLASIALaura Koutsky; Fiscal Year: 2007..S.-based study of the accuracy and cost effectiveness of primary screening by traditional Pap and cervical HPV DNA testing...
- Cervical Cancer Screening in LesbiansJ Tracy; Fiscal Year: 2007..rates have decreased significantly during the last 50 years due to widespread screening with the Papanicolaou (Pap) test...
- Nitric Oxide in Pulmonary HypertensionSerpil Erzurum; Fiscal Year: 2009Pulmonary arterial hypertension (PAH) is a fatal disease associated with increased pulmonary artery pressure (PAP) and abnormalities in blood vessel growth...
- Telecolposcopy in a Primary Care Women's Health ClinicAna Maria Lopez; Fiscal Year: 2006..majority of patients with frank cervical carcinoma and cervical dysplasia, its precursor lesion, are asymptomatic, Pap smear screening provides the best approach to early detection...
- Facilitating Follow-up Adherence for Abnormal Pap SmearsSuzanne Miller; Fiscal Year: 2007..Adherence to diagnostic colposcopy and follow-up regimens is crucial after an abnormal Pap smear result indicative of oncogenic HPV (approximately 75 percent of abnormalities), since early detection and ..
- Aberrant DNA Methylation as a Biomarker of HSIL in Liquid-based Pap TestsKAREN GUSTAFSON; Fiscal Year: 2007In the United States, current screening programs for cervical cancer using the Papanicolaou (Pap) test are aimed at early detection and treatment of precancerous high-grade squamous intraepithelial lesions (HSIL). Of the greater than 3...
- ACCISS: Activating Collaborative CIS Support ServicesBonnie Spring; Fiscal Year: 2007..work investigates how to connect the CIS to low-income urban African-American and Hispanic women with abnormal PAP tests...
- Continuous Cardiac Output & Filling Pressure MonitoringRamakrishna Mukkamala; Fiscal Year: 2007..On the other hand, pulmonary artery pressure (PAP) is measured continuously and automatically with the catheter...
- A Pap Test Intervention to Enhance Decision Making among Pacific Islander WomenSORA PARK contact TANJASIRI; Fiscal Year: 2010A Pap Test Intervention to Enhance Decision Making among PI Women ABSTRACT Despite the fact that cervical cancer is one of the most preventable of cancers, it remains one of the top five causes of cancer deaths in the U.S...
- REGULATION OF PHOSPHOLIPID SYNTHESISGeorge M Carman; Fiscal Year: 2010..The PAH1-encoded phosphatidic acid phosphatase (PAP1) catalyzes the Mg2+dependent dephosphorylation of phosphatidic acid to yield diacylglycerol and Pi...
- GM-CSF is required for macrophage surfactant catabolismTracey Bonfield; Fiscal Year: 2006Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease of unknown etiology...
- Pyrophosphorolysis-activatable helicase dependent amplification assay for lung caBERTRAND LEMIEUX; Fiscal Year: 2007..of DNA only if the 3'end is matched to its target; hence the name pyrophosphorolysis-activated polymerization (PAP) for this technology developed by the City of Hope hospital. Not all DNA polymerases efficiently perform PAP...
- GM-CSF THERAPY FOR ALVEOLAR PROTEINOSISMary Jane Thomassen; Fiscal Year: 2003DESCRIPTION:(Adapted from Investigator's abstract): Pulmonary alveolar proteinosis (PAP) is a very rare lung disease characterized by the accumulation of surfactant material within the alveoli...
- Alkoxypsoralens, Small Molecule Blockers of the Voltage-Gated Kv1.3 ChannelHeike Wulff; Fiscal Year: 2006..3 blockers. With the alkoxypsoralen PAP-1 my laboratory recently identified the first small molecule inhibitor of Kv1...
- Alkoxypsoralens, Small Molecule Blockers of the Voltage-Gated Kv1.3 ChannelHeike Wulff; Fiscal Year: 2009..3 blockers. With the alkoxypsoralen PAP-1 my laboratory recently identified the first small molecule inhibitor of Kv1...
- Alkoxypsoralens, Small Molecule Blockers of the Voltage-Gated Kv1.3 ChannelHeike Wulff; Fiscal Year: 2009..3 blockers. With the alkoxypsoralen PAP-1 my laboratory recently identified the first small molecule inhibitor of Kv1...
- Alkoxypsoralens, Small Molecule Blockers of the Voltage-Gated Kv1.3 ChannelHeike Wulff; Fiscal Year: 2007..3 blockers. With the alkoxypsoralen PAP-1 my laboratory recently identified the first small molecule inhibitor of Kv1...
- PHOSPHOINOSITIDE SIGNALING TO AND WITHIN THE NUCLEUSRichard A Anderson; Fiscal Year: 2010..In this context, we have discovered that PIPKI1 interacts with a novel poly A polymerase (PAP) now called Star-PAP. Star-PAP is dramatically and specifically stimulated by PIP2...
- PHOSPHOINOSITIDE SIGNALING TO AND WITHIN THE NUCLEUSRichard A Anderson; Fiscal Year: 2010..In this context, we have discovered that PIPKI1 interacts with a novel poly A polymerase (PAP) now called Star-PAP. Star-PAP is dramatically and specifically stimulated by PIP2...
- PAP adherence and real-world driving safety in OSAMatthew Rizzo; Fiscal Year: 2010..in automobile drivers with obstructive sleep apnea (OSA) and to determine the amount of positive airway pressure (PAP) use needed to produce clinically meaningful improvements in driver safety...
- Cytokine Dysregulation in GM-CSF AutoimmunityMary Jane Thomassen; Fiscal Year: 2007Idiopathic pulmonary alveolar proteinosis (PAP) is a newly recognized autoimmune disorder characterized by neutralizing autoantibodies to granulocyte-macrophage colony stimulating factor (GMCSF) and severely dysregulated lung surfactant ..
- DNA METHYLATION AND PILI GENE REGULATIONDavid Low; Fiscal Year: 2000..of this proposal is to understand the molecular basis of phase variation of the pyelonephritis-associated pili (pap) operon of uropathogenic Escherichia coli...
- Enabling Sleep Apnea Patient-Centered Care Via an Internet InterventionCarl Stepnowsky; Fiscal Year: 2007..of this proposal is designed as a randomized, controlled clinical trial?Usual Care patients (control) versus i-PAP patients (intervention)...
- DNA METHYLATION AND PILI GENE REGULATIONDavid Low; Fiscal Year: 2006..DAM), leucine-responsive regulatory protein (Lrp), and PapI orchestrate the reversible switch between OFF and ON Pap pili expression states in uropathogenic Escherichia coli (UPEC)...
- Glycan Biomarkers of Prostate Cancer in Prostatic FluidsRichard R Drake; Fiscal Year: 2010Prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP) are glycoproteins secreted by prostate epithelial cells, and have a long clinical history of use as serum biomarkers of prostate cancers...
