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Genomes and Genes
| MESDC2SummaryGene Symbol: MESDC2 Description: mesoderm development candidate 2 Alias: BOCA, MESD, LDLR chaperone MESD, mesoderm development protein, renal carcinoma antigen NY-REN-61 Species: human Top Publications
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Publications
Neurotrophin-3 in the development of the enteric nervous systemALCMENE CHALAZONITIS
Department of Anatomy and Cell Biology, Columbia University, College of Physicians and Surgeons, 630W, 168th Street, New York, NY 10032, USA
Prog Brain Res 146:243-63. 2004..Chalazonitis, 1996, Mol. Neurobiol., 12: 39-53; Sieber-Blum, 1999, Neurotrophins and the Neural Crest, CRC Press, Boca Raton)...- Lower Miocene stratigraphy along the Panama Canal and its bearing on the Central American PeninsulaMichael Xavier Kirby
Center for Tropical Paleoecology and Archaeology, Smithsonian Tropical Research Institute, Balboa, Republic of Panama
PLoS ONE 3:e2791. 2008..of a stratigraphic dispute: To wit, is the terrestrial Cucaracha Formation older or younger than the marine La Boca Formation? Previous stratigraphic studies of the Panama Canal Basin have suggested that the Cucaracha Formation .. - Homonymous Hemianopia: A Critical Analysis of Optical Devices, Compensatory Training, and NovaVisionVictoria S Pelak
Victoria S Pelak, MD University of Colorado Health Sciences Center, PO Box 6510, Mailstop F727, Aurora, CO 80045, USA
Curr Treat Options Neurol 9:41-7. 2007..This strategy is trademarked as visual restoration therapy (VRT) by NovaVision (Boca Raton, FL), which began marketing its commercialized therapy program in 2003 for the treatment of visual loss .. - A tribute to Charles David Kelman MD: ophthalmologist, inventor and pioneer of phacoemulsification surgerySuresh K Pandey
Intraocular Implant Unit, Sydney Eye Hospital, Sydney, New South Wales, Australia
Clin Experiment Ophthalmol 32:529-33. 2004Charles David Kelman was born in Brooklyn, New York, USA, on 23 May 1930 and passed away in Boca Raton, Florida, USA, on 1 June 2004 at the age of 74 years after a long battle with cancer... - Six Sigma and Lean concepts, a case study: patient centered care model for a mammography centerMark Viau
New Hospital Development, Boca Raton Community Hospital, USA
Radiol Manage 29:19-28; quiz 30-2. 2007b>Boca Raton Community Hospital in South Florida decided to increase return while enhancing patient experience and increasing staff morale... - Cloning and characterization of chicken growth hormone binding protein (cGHBP)J S Lau
Department of Zoology, 5N 12, Kadoorie Biological Sciences Building, The University of Hong Kong, Pokfulam Road, Hong Kong, HKSAR, China
Domest Anim Endocrinol 33:107-21. 2007..Growth hormone. Boca Raton: CRC Press; 1995]. GHR is a transmembrane protein responsible for signal transduction upon GH binding... - [Present state of diseases and other signs of reef deterioration at seven coral reefs at Los Roques Archipelago National Park, Venezuela]Adriana Garcia
Escuela de Biologia, Universidad Central de Venezuela, Caracas, Venezuela
Rev Biol Trop 51:173-80. 2003..Archipiélago de Los Roques, Venezuela: Arrecife de herradura, Arrecife costanero, both at Dos Mosquises Sur Key, Boca de Cote, Carenero, Crasquí and Pelona de Rabusquí... - Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in menDouglas P Kiel
Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA 02131, USA
Bone 40:587-96. 2007..LRP5 haplotypes were transiently co-expressed with Wnt3a, MesD and Dkk1 in HEK293 cells and their activity evaluated by the TCF-Lef reporter assay... - Impact of folivory on photosynthesis is greater than the sum of its holesA R Zangerl
Department of Entomology, University of Illinois at Urbana Champaign, 505 South Goodwin Avenue, Urbana, IL 61801, USA
Proc Natl Acad Sci U S A 99:1088-91. 2002..C. (1989) in Insect-Plant Interactions, ed. Bernays, E. A. (CRC, Boca Raton), pp. 135-151.]... - Developing a multimedia model of chemical dynamics in an urban areaM L Diamond
Department of Geography, University of Toronto, Ont, Canada
Chemosphere 44:1655-67. 2001..Mackay (Multimedia Environmental Models: The Fugacity Approach, Lewis Publishers, Boca Raton, FL, 1991), consists of six compartments: air, surface water, sediment, soil, vegetation, and an organic film .. - Miniature carrier with six independently moveable electrodes for recording of multiple single-units in the cerebellar cortex of awake ratsB P Vos
Laboratory Theoretical Neurobiology, Born Bunge Foundation, University of Antwerp, Belgium
J Neurosci Methods 94:19-26. 1999..In: Nicolelis MAL, editor. Methods for Neural Ensemble Recordings, CRC Methods in Neuroscience Series. Boca Raton, FL: CRC Press LLC, 1999, pp. 79-100)... - Live CT imaging of sound reception anatomy and hearing measurements in the pygmy killer whale, Feresa attenuataEric W Montie
Department of Science and Mathematics, University of South Carolina Beaufort, Bluffton, SC 29909, USA
J Exp Biol 214:945-55. 2011In June 2008, two pygmy killer whales (Feresa attenuata) were stranded alive near Boca Grande, FL, USA, and were taken into rehabilitation... - Perkinsus marinus in pleasure oyster Crassostrea corteziensis from Nayarit, Pacific coast of MéxicoJ Cáceres-Martínez
Centro de Investigacion Cientifica y de Educacion Superior de Ensenada, CICESE, Tijuana Ensenada, Mexico
J Invertebr Pathol 99:66-73. 2008..S78416.1). The prevalence of P. marinus varied from 1 to 5% in Boca del Camichín and from 1 to 6% in Pozo Chino. In general, the intensity of infection was moderate... - The relevance of Choukroun's platelet-rich fibrin and metronidazole during complex maxillary rehabilitations using bone allograft. Part II: implant surgery, prosthodontics, and survivalAlain Simonpieri
Department of Periodontology, Turin University, Turin, Italy
Implant Dent 18:220-9. 2009..Gardens, FL) and 130 implants with microthreaded collar (46 from AstraTech, Mölndal, Sweden; 84 from Intra-Lock, Boca Raton, FL)... - MESD is essential for apical localization of megalin/LRP2 in the visceral endodermJanet K Lighthouse
Department of Biochemistry and Cell Biology and the Center for Developmental Genetics, Stony Brook University, Stony Brook, New York
Dev Dyn 240:577-88. 2011Deletion of the Mesd gene region blocks gastrulation and mesoderm differentiation in mice. MESD is a chaperone for the Wnt co-receptors: low-density lipoprotein receptor-related protein (LRP) 5 and 6 (LRP5/6)... - Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteinsJoaquim Culi
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
EMBO J 23:1372-80. 2004..Members of the low-density lipoprotein receptor (LDLR) family require the chaperone called Boca in Drosophila or its ortholog, Mesoderm development, in the mouse... - [Carotenogenesis of five strains of the algae Dunaliella sp. (Chlorophyceae) isolated from Venezuelan hypersaline lagoons]Miguel Guevara
Laboratorio de Acuicultura, extensión Plancton, Dpto Biología Pesquera, Instituto Oceanografico de Venezuela, Universidad de Oriente, Cumana 6101, Venezuela
Rev Biol Trop 53:331-7. 2005..isolated from Venezuelan hypersaline lagoons (Araya, Coche, Peonia, Cumaraguas. and Boca Chica) and one strain from a reference collection (Dunaliella salina, LB1644)... - Requirement for natively unstructured regions of mesoderm development candidate 2 in promoting low-density lipoprotein receptor-related protein 6 maturationVidyasagar Koduri
Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Biochemistry 46:6570-7. 2007..Productive maturation of these proteins relies on an ER-resident protein called mesoderm development candidate 2 (MESD) in mammals and Boca in Drosophila... - Comparison of total body tissue interface pressure of specialized pressure-relieving mattressesWilliam L Hickerson
Medical and Surgical Associates of Georgia, PC, 3623 J Dewey Gray Circle, Suite 309, Augusta, GA 30909, USA
J Long Term Eff Med Implants 14:81-94. 2004.... - Boca: an open-source RDF store for building Semantic Web applicationsLee Feigenbaum
IBM Internet Technology, Cambridge, MA, USA
Brief Bioinform 8:195-200. 2007This article presents the design goals and features of the open-source Boca RDF server in the context of a community of cancer-tumor modeling investigators... - Physical localization of the mesoderm development (mesd) functional regionM E Wines
Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
Genomics 68:322-9. 2000The mesoderm development (mesd) functional interval is essential for primitive streak formation and mesoderm induction. Mesd is defined by overlapping albino (c) deletions on chromosome 7... - [Age and growth of the grunt, Haemulon steindachneri (Perciformis: Haemulidae), from the Southwest area of Margarita Island, Venezuela]Misael Morales
Escuela de Ciencias Aplicadas del Mar, Universidad de Oriente, Núcleo Nueva Esparta, Venezuela
Rev Biol Trop 58:299-310. 2010..A total of 953 individuals were captured by the handcrafted fleet from Boca del Rio (Margarita Island) between July 2005 and June 2006... - Determination of serum IgG antibodies to Bacillus anthracis protective antigen in environmental sampling workers using a fluorescent covalent microsphere immunoassayR E Biagini
Division of Applied Research and Technology, Biomonitoring and Health Assessment Branch, Biological Monitoring Laboratory Section, CDC NIOSH MS C 26, Robert A Taft Laboratories, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Occup Environ Med 61:703-8. 2004..To evaluate potential exposure to Bacillis anthracis (Ba) spores in sampling/decontamination workers in the aftermath of an anthrax terror attack... - Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in DrosophilaJoaquim Culi
Department of Biochemistry and Molecular Biophysics, Center for Neurobiology and Behavior, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA
Cell 112:343-54. 2003..Here we describe boca, an evolutionarily conserved gene in Drosophila melanogaster, which encodes an endoplasmic reticulum protein that .. - A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V)Richard J Murrills
Department of Osteoporosis and Frailty, Women s Health and Musculoskeletal Biology, Wyeth Research, Collegeville, Pennsylvania 19426, USA
J Cell Biochem 108:1066-75. 2009..However, co-transfection of LRP5 with the chaperone protein MesD (which itself does not bind Dkk1) or Kremen-2 (a known Dkk1 receptor), or both, resulted in a marked enhancement of .. - [Occurrence of Mansonella ozzardi (Nematoda, Onchocercidae) in riverine communities of the Purus river, Boca do Acre municipality, Amazonas State, Brazil]Jansen Fernandes Medeiros
Coordenação de Pesquisas em Ciências da Saúde, Instituto Nacional de Pesquisas da Amazonia, Manaus, Brasil
Cad Saude Publica 25:1421-6. 2009..The research was conducted in communities on the Purus River, Boca do Acre municipality, Amazonas State, Brazil. Prevalence was measured using the thick smear method... - The year in reviewAnne Greenough
Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, London, UK
Paediatr Respir Rev 10:2-5. 2009..other' viruses (RSV, influenza, adenovirus, parainfluenza, rhinovirus, human metapneumovirus [hMPV], coronavirus, boca-virus, enterovirus, paraechovirus) has been investigated... - A complete NMR spectral assignment of the conserved region of the MESD protein, MESD(12-155)Jianglei Chen
Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201, USA
Biomol NMR Assign 1:3-5. 2007..Mesoderm development (MESD) protein is a 195-residue protein that functions as a specialized molecular chaperone to promote the proper folding .. - Cooperative folding and ligand-binding properties of LRP6 beta-propeller domainsChia Chen Liu
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 284:15299-307. 2009..show that BP1, BP2, and BP4 each can be folded and secreted, and their secretion was enhanced by co-expression of Mesd, a molecular chaperone essential for LRP6 folding and maturation... - [Growth and mortality of the fish Haemulon aurolineatum (Teleostei: Haemulidae) from southwest of Margarita Island, Venezuela]Edwis Bravo
Escuela de Ciencias Aplicadas del Mar, Departamento de Acuacultura, Instituto de Investigaciones Cientificas, Núcleo de Nueva Esparta, Universidad de Oriente, Venezuela
Rev Biol Trop 57:105-12. 2009..A sample of 1,378 males and 1,143 females from artisanal fishing vessels of Boca del Río was analyzed. The common relation for both sexes was expressed by the equation P=0.038*L(2.87)... - Nonlinear analysis of the heartbeats in public patient ECGs using an automated PD2i algorithm for risk stratification of arrhythmic deathJAMES E SKINNER
Vicor Technologies, Inc Bangor, PA, USA
Ther Clin Risk Manag 4:549-57. 2008..The results were blindly calculated by automated software (Vicor 2.0, Vicor Technologies, Inc., Boca Raton, FL) and showed all analyzable VF/VT files had PD2i < 1.4 and all analyzable controls had PD2i > 1.4... - Efficacy of drinking-water treatment residual in controlling off-site phosphorus losses: a field study in FloridaS Agyin-Birikorang
Soil and Water Sci Dep, Univ Florida, Gainesville, FL 32611 0510, USA
J Environ Qual 38:1076-85. 2009..We monitored the effects of three organic sources of P (poultry manure, Boca Raton biosolids, Pompano biosolids) or triple superphosphate co-applied with an aluminum-based WTR (Al-WTR) on soil .. - Wnt signaling in bone metabolismTakuo Kubota
Department of Pediatrics, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita, Osaka 565 0871, Japan
J Bone Miner Metab 27:265-71. 2009..b>Mesd might be one of target molecules to increase the quantity of LRP5/6 in the plasma membrane... - Porcine bocaviruses: genetic analysis and prevalence in Chinese swine populationH B Zhang
Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China
Epidemiol Infect 139:1581-6. 2011..protein (VP1) classification, the six reported porcine bocaviruses were grouped into four species: PoBoV1 (porcine boca-like virus or PBoLV), PoBoV2 (porcine parvovirus 4 or PPV4), PoBoV3 (PBoV1/PBoV2) and PoBoV4 (6V/7V), with PoBoV3 .. - Detection of a novel porcine boca-like virus in the background of porcine circovirus type 2 induced postweaning multisystemic wasting syndromeAnne Lie Blomström
Department of Biomedical Sciences and Veterinary Public Health, Division of Microbiology and Food Safety, Swedish University of Agricultural Sciences, S 750 07 Uppsala, Sweden
Virus Res 146:125-9. 2009..By comparative analysis of the nucleotide sequences and phylogenetic studies we propose that this is a novel porcine parvovirus, with genetic relationship to bocaviruses... - Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivoCuihong Lin
Department of Biochemistry and Molecular Biology, Drug Discovery Division, Southern Research Institute, Birmingham, AL 35255, United States
FEBS Lett 585:3120-5. 2011b>Mesd is a specialized chaperone for Wnt co-receptor low-density lipoprotein receptor-related protein-5 (LRP5) and LRP6, which contain four ?-propeller/epidermal growth factor modules, named E1 to E4 from N- to C-terminal, in their .. - Genetic detection and analysis of porcine bocavirus type 1 (PoBoV1) in European wild boar (Sus scrofa)Daniel Cadar
Department of Infectious Diseases, University of Agricultural Sciences and Veterinary Medicine, Cluj Napoca, Romania
Virus Genes 43:376-9. 2011..The first such porcine bocavirus (PoBoV1), described as boca-like virus (PBo-likeV), was discovered in PMWS affected pigs in Sweden... - Development of a novel TaqMan-based real-time PCR assay for the detection of porcine boca-like virus (Pbo-likeV)Bin Li
Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Animal Diseases, Diagnostics, and Immunology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio products, Nanjing 210014, Jiangsu Province, PR China
Virol J 8:357. 2011The recently discovered porcine boca-like virus (Pbo-likeV) is a member of the Parvoviridae family, genus Bocavirus, and it is potentially associated with swine disease... - The structure of MESD45-184 brings light into the mechanism of LDLR family foldingChristian Kohler
Department of NMR Supported Structural Biology, Leibniz Institut fur Molekulare Pharmakologie, Robert Rossle Str 10, 13125 Berlin, Germany
Structure 19:337-48. 2011Mesoderm development (MESD) is a 224 amino acid mouse protein that acts as a molecular chaperone for the low-density lipoprotein receptor (LDLR) family... - Structural characterization of the Boca/Mesd maturation factors for LDL-receptor-type ? propeller domainsMark N Collins
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
Structure 19:324-36. 2011..The Boca/Mesd chaperone family specifically promotes folding and trafficking of the YWTD ? propeller-EGF domain pair found in the .. - Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6Jianglei Chen
Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201, USA
Structure 19:313-23. 2011..Here, we show two structural domains in MESD, a specialized chaperone for LRP5/6, carry out dual functions... - Weather, geography, and vehicle-related hyperthermia in childrenAndrew Grundstein
University of Georgia, Athens
Geogr Rev 101:353-70. 2011..The vhi indicates that the Memphis, West Palm Beach-Boca Raton, and Las Vegas metropolitan areas are the most dangerous places for vehicle-related hyperthermia... - Acetylcholinesterase and metallothionein in oysters (Crassostrea corteziensis) from a subtropical Mexican Pacific estuaryY Y Bernal-Hernández
Posgrado en Ciencias Biológico Agropecuarias y Pesqueras, Unidad Académica de Agricultura, Xalisco, Nayarit, Mexico
Ecotoxicology 19:819-25. 2010..The aim of this study was to evaluate AChE activity and MT's content in Crassostrea corteziensis from Boca de Camichín estuary... - Parasites of the pleasure oyster Crassostrea corteziensis cultured in Nayarit, MexicoJorge Cáceres-Martínez
Centro de Investigacion Cientifica y de Educacion Superior de Ensenada, Carretera Ensenada Tijuana Number 3918, Zona Playitas, Ensenada, Baja California 22860, Mexico
J Aquat Anim Health 22:141-51. 2010..A histopathological survey carried out in two estuaries, Boca del Camichín and Pozo Chino, revealed the presence of hypertrophied gametes, rickettsiales-like prokaryotes (RLPs),.. - The pH-dependent surface charging and points of zero charge: V. UpdateMarek Kosmulski
Department of Electrochemistry, Lublin University of Technology, Nadbystrzycka 38, PL 20618 Lublin, Poland
J Colloid Interface Sci 353:1-15. 2011..Kosmulski, Surface Charging and Points of Zero Charge, CRC, Boca Raton, FL, 2009] and of its previous update [J. Colloid Interface Sci. 337 (2009) 439]... - Prediction and verification of possible reef-fish spawning aggregation sites in Los Roques Archipelago National Park, VenezuelaJ Boomhower
Fulbright Student Scholarship Programme, Universidad Simon Bolivar, Apartado 89000, Caracas 1080A, Venezuela
J Fish Biol 77:822-40. 2010..not observed, possible indirect evidence of spawning aggregations was found for Lutjanus analis at Cayo Sal and Boca de Sebastopol, Lutjanus apodus at Cayo Sal, Lutjanus cyanopterus at Cayo Sal and Piedra La Guasa and Epinephelus .. - Studies of porcine circovirus type 2, porcine boca-like virus and torque teno virus indicate the presence of multiple viral infections in postweaning multisystemic wasting syndrome pigsAnne Lie Blomström
Department of Biomedical Sciences and Veterinary Public Health, Section of Virology, Swedish University of Agricultural Sciences, Uppsala, Sweden
Virus Res 152:59-64. 2010..animals and 24 pigs without PMWS were screened by PCR for the presence of PCV-2, TTV-1, TTV-2 and porcine boca-like virus (Pbo-likeV)... - Localizable and highly sensitive calcium indicator based on a BODIPY fluorophoreMako Kamiya
Institute of Chemical Sciences and Engineering, Ecole Polytechnique Federale de Lausanne, CH 1015, Lausanne, Switzerland
Anal Chem 82:6472-9. 2010..The underivatized BODIPY-based Ca2+ indicator (BOCA-1) shows a 250-fold increase in fluorescence intensity upon Ca2+ binding... - Motivational interviewing in relational contextWilliam R Miller
University of New Mexico
Am Psychol 65:298-9. 2010..2006), the UK Alcohol Treatment Trial (UKATT Research Team, 2005), and Project MATCH (Babor & Del Boca, 2003)... - Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cellsWenyan Lu
Department of Biochemistry and Molecular Biology, Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, Alabama 35255 5305, USA
Biochemistry 49:4635-43. 2010b>Mesd is a specialized chaperone for low-density lipoprotein receptor-related protein 5 (LRP5) and LRP6... - High-dose estrogen as salvage hormonal therapy for highly refractory metastatic breast cancer: a retrospective chart reviewReshma L Mahtani
Boca Raton Comprehensive Cancer Center, Boca Raton, Florida 33428, USA
Clin Ther 31:2371-8. 2009..This is due in part to the introduction of tamoxifen in the 1970s, which was proven to be equivalent in efficacy and associated with fewer adverse events (AEs)... - Effect of titanium implant surface nanoroughness and calcium phosphate low impregnation on bone cell activity in vitroVincenzo Bucci-Sabattini
Department of Oral Sciences, University of Pavia, and Private Practice, Centro Diagnostico Chirurgica Magentino, Magenta Milano, Italy
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:217-24. 2010..microtopography but distinct chemistry and nanotopography (sandblasted/acid-etched surface as control group, and calcium phosphate (CaP) low impregnated surface (Ossean) as test group, both from Intra-Lock, Boca Raton, FL) were evaluated. - Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt SignalingShuo Chen
Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
Dev Cell 21:848-61. 2011..EM reconstruction of the LRP6 platform bound to chaperone Mesd exemplifies a binding mode spanning PE pairs... - Tree recruitment in an empty forestJohn Terborgh
Duke University Center for Tropical Conservation, Nicholas School of the Environment and Earth Sciences, Durham, North Carolina 27708, USA
Ecology 89:1757-68. 2008..Large vertebrates were severely depleted at one site, Boca Manu (BM), whereas the other, Cocha Cashu Biological Station (CC), supported an intact fauna... - Convergent habitat segregation of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in southeastern Brazil and FloridaMarieta A H Braks
Florida Medical Entomology Laboratory, University of Florida IFAS, 200 9th Street SE, Vero Beach, FL 32962, USA
J Med Entomol 40:785-94. 2003..of two cities (Rio de Janeiro and Nova Iguaçu) in Rio de Janeiro State, Brazil, and in two cities (Palm Beach and Boca Raton) in Florida. Oviposition trap collections were performed in urban, suburban, and rural habitats in both areas... - Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarityJen Chih Hsieh
Department of Biochemistry and Cell Biology, Center for Developmental Genetics, State University of New York, Stony Brook, Stony Brook, NY 11794, USA
Cell 112:355-67. 2003..Here, we demonstrate that mesd, a gene identified in the mesoderm development (mesd) deletion interval on mouse chromosome 7, is essential for .. - Coaxing the LDL receptor family into the foldJoachim Herz
Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Cell 112:289-92. 2003..In this issue of Cell, both Culi and Mann and Hsieh et al. report on Boca/MESD, a highly conserved chaperone required for transport of LDLR family proteins to the cell surface... - Protective effects of the alpha 2-adrenoceptor antagonist, dexefaroxan, against degeneration of the basalocortical cholinergic system induced by cortical devascularization in the adult ratT Debeir
INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, F 75013 Paris, France
Neuroscience 115:41-53. 2002..C., 1994. In: Briley, M., Marien, M. (Eds.), Noradrenergic Mechanisms in Parkinson's Disease. CRC Press, Boca Raton, FL, pp... - Differential skeletal preservation at Windover Pond: causes and consequencesChristopher M Stojanowski
Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87131, USA
Am J Phys Anthropol 119:15-26. 2002..1997] Forensic taphonomy, Boca Raton: CRC Press; Waldron [1987] Death, decay and reconstruction, Manchester: Manchester University Press; Willey .. - Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assemblyBrian L Marquez
College of Pharmacy, Oregon State University, Corvallis, Oregon 97331, USA
J Nat Prod 65:866-71. 2002Hectochlorin (1) was isolated from marine isolates of Lyngbya majuscula collected from Hector Bay, Jamaica, and Boca del Drago Beach, Bocas del Toro, Panama. The planar structure was deduced by one- and two-dimensional NMR spectroscopy... - Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysisM E Wines
Institute for Cell and Developmental Biology, Graduate Program in Genetics, Stony Brook, New York 11794 5215, USA
Genomics 72:88-98. 2001..Two of the novel genes, mesdc1 and mesdc2, are located within the mesd critical region defined by BAC transgenic rescue... - In Southern Africa, brown oculocutaneous albinism (BOCA) maps to the OCA2 locus on chromosome 15q: P-gene mutations identifiedP Manga
Department of Human Genetics, School of Pathology, The South African Institute for Medical Research and University of the Witwatersrand, Johannesburg, 2000, South Africa
Am J Hum Genet 68:782-7. 2001In southern Africa, brown oculocutaneous albinism (BOCA) is a distinct pigmentation phenotype... - Identification of P gene mutations in individuals with oculocutaneous albinism in sub-Saharan AfricaR Kerr
Department of Human Genetics, The South African Institute for Medical Research and University of the Witwatersrand, Johannesburg, South Africa
Hum Mutat 15:166-72. 2000..also responsible for the milder hypopigmentation phenotype seen in individuals with brown oculocutaneous albinism (BOCA)... - Origin of life on earth and Shannon's theory of communicationH P Yockey
Comput Chem 24:105-23. 2000..Cold Spring Harbor Laboratory Press, Boca Raton, FL)... - The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunitA E Dubin
R W Johnson Pharmaceutical Research Institute, San Diego, California 92121, USA
J Biol Chem 274:30799-810. 1999..A., and Hope, A. G. (1995) in Ligand-Voltage-Gated Ion Channels (North, R., ed) pp. 177-211, CRC Press, Inc., Boca Raton, FL), it has been proposed that native receptors may exist as heteromers (Fletcher, S., and Barnes, N. M... - Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature in 1993 to 1994 and by the National Toxicology Program in 1995 to 1996L S Gold
Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720 3202, USA
Environ Health Perspect 107:527-600. 1999..b>Boca Raton FL:CRC Press, 1997] and with our web site (http://potency.berkeley... - Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 geneP Manga
Department of Human Genetics, South African Institute for Medical Research, Johannesburg, South Africa
Am J Hum Genet 61:1095-101. 1997..It is caused by mutations in the P gene on chromosome 15. Brown OCA (BOCA) and rufous OCA (ROCA) account for the majority of the remaining phenotypes... - Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changesM L Ludwig
Department of Biological Chemistry, University of Michigan, Ann Arbor 48109 1055, USA
Biochemistry 36:1259-80. 1997..L. (1992) in Chemistry and Biochemistry of Flavoenzymes III (Müller, F., Ed.) pp 427-466, CRC Press, Boca Raton, FL]. Analyses reported in this paper confirm that, in crystals of wild-type oxidized C... - PACS--and beyond. A journey to the digital promised landMark A Viau
Boca Raton Community Hospital, FL, USA
Radiol Manage 26:36-40. 2004..This fact was evident from the inception of the PACS project at Boca Raton Community Hospital (BRCH)... - Evaluation of a novel pedicle probe for the placement of thoracic and lumbosacral pedicle screwsJonathan N Grauer
Rothman Institute, Jefferson University, Philadelphia, Pennsylvania, USA
J Spinal Disord Tech 17:492-7. 2004..The pedicle is generally cannulated with a gearshift probe or curette. SafePath (Mekanika, Boca Raton, FL) is an alternative pedicle probe designed for pedicle cannulation... - A convenient fluorometric method to study sulfur mustard-induced apoptosis in human epidermal keratinocytes monolayer microplate cultureRadharaman Ray
Biochemical Pharmacology Branch, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010 5400, USA
Drug Chem Toxicol 28:105-16. 2005..I., Ford, R. D., eds. Medical Defense Against Mustard Gas: Toxic Mechanisms and Pharmacological Implications. Boca Raton: CRC Press, pp. 43-78.], is a chemical warfare agent as well as a potential terrorism agent... - Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with MesdTakuo Kubota
Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
J Bone Miner Res 23:1661-71. 2008..rs mutant showed decreased targeting to plasma membrane because of reduced interaction with Mesoderm development (Mesd), a chaperone for Lrp6, leading to impaired Wnt/beta-catenin signaling... - Does the position of the femoral tunnel affect the laxity or clinical outcome of the anterior cruciate ligament-reconstructed knee? A clinical, prospective, randomized, double-blind studyClaus Fink Jepsen
Randers Central Hospital, Randers, Denmark
Arthroscopy 23:1326-33. 2007.... - Prospective examination of the efficacy of 2 topical over-the-counter cosmeceutical creams for rapid treatment of facial rhytidsSam P Most
Division of Facial Plastic and Reconstructive Surgery, 801 Welch Rd, Stanford, CA 94305, USA
Arch Facial Plast Surg 9:340-3. 2007..Freeze 24/7 International LLC, New York, New York) and LiftFusion Micro-Injected M-Tox Transdermal Face Lift (Fusionbeauty, Inc, Boca Raton, Florida)-against placebo (Nutraderm Therapeutic Lotion; Healthpoint, Inc, San Antonio, Texas). - Surface applied water treatment residuals affect bioavailable phosphorus losses in Florida sandsOlawale O Oladeji
Crop and Soil Science Department, 512 Plant and Soil Science Bldg, Michigan State University, East Lansing, MI 48824, USA
J Environ Manage 88:1593-600. 2008..Four P-sources, namely poultry manure, Boca Raton biosolids (high water-soluble P), Pompano biosolids (moderate water-soluble P), and triple super phosphate (.. - Intrusive luxation: a case reportAna Helena Gonçalves de Alencar
Department of Endodontics, School of Dentistry, Federal University of Goias, Brazil
Dent Traumatol 23:307-12. 2007..The patient GCSA, aged 15 years, attended the community project 'Lugar de dente é na boca' ('teeth should be in the mouth') of the Federal University of Goiás, Brazil, 1 week after complete intrusion of .. - Biomimetics--using nature to inspire human innovationYoseph Bar-Cohen
Jet Propulsion Lab, California Institute of Technology, Pasadena, CA 91109 8099, USA
Bioinspir Biomim 1:P1-P12. 2006..methods, systems, and many other benefits (Bar-Cohen Y (ed) 2005 Biomimetics-Biologically Inspired Technologies (Boca Raton, FL: CRC Press) pp 1-552)... - Effect of clozapine on interval timing and working memory for time in the peak-interval procedure with gapsCatalin V Buhusi
Duke University, Department of Psychology and Neuroscience, Durham, NC 27708, United States
Behav Processes 74:159-67. 2007..In: Meck, W.H. (Ed.), Functional and Neural Mechanisms of Interval Timing. CRC Press, Boca Raton, FL, pp. 317-338]... - Modulation of LRP6-mediated Wnt signaling by molecular chaperone MesdYonghe Li
Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, MO 63110, USA
FEBS Lett 580:5423-8. 2006LRP6 is a Wnt coreceptor at the cell surface. Here, we report that a specialized molecular chaperone Mesd modulates LRP6-mediated Wnt signaling and how different LRP6 mutants exhibit differential effects on Wnt signaling... - Respiratory Drug Delivery X. Boca Raton, FL, USA, 24-27 April 2006Steve Newman
Expert Opin Drug Deliv 3:549-52. 2006There were approximately 700 delegates who attended Respiratory Drug Delivery X (RDD-X) at the Boca Raton Resort and Club in Boca Raton, Florida, between the 24th and 27th April 2006... - Neuropeptides and nitric oxide synthase in the gill and the air-breathing organs of fishesGiacomo Zaccone
Department of Animal Biology and Marine Ecology, Section of Cell Biology, Comparative Neurobiolgy and Biomonitoring, Faculty of Science, University of Messina, Italy
J Exp Zool A Comp Exp Biol 305:428-39. 2006..XA. Orlando: Academic Press. p 185-227; Donald. 1998. In: Evans DH, editor. The physiology of fishes, 2nd edition. Boca Raton: CRC Press. p 407-439)... - Capturing the moment: innovative approaches to daily alcohol assessmentDan J Neal
Department of Psychology, The University of Texas at Austin, Austin, Texas 78712 0187, USA
Alcohol Clin Exp Res 30:282-91. 2006..Del Boca; "Using Interactive Voice Response Technology to Assess the Alcohol-Victimization Link" by Kathleen Parks,.. - A Bayesian approach to modeling dynamic effective connectivity with fMRI dataSourabh Bhattacharya
Applied Statistics Unit, Indian Statistical Institute, 203 B T Road, Kolkata 700 108, India
Neuroimage 30:794-812. 2006..P., Louis, T.A., 2000. Bayes and Empirical Bayes Methods for Data Analysis (2nd ed.). Chapman and Hall, Boca Raton)... - Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand bindingYonghe Li
Department of Pediatrics, St Louis Children s Hospital, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
J Cell Sci 118:5305-14. 2005..Here we test whether Mesd, a newly identified chaperone for members of the low-density lipoprotein receptor family, also binds to mature .. - Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25)Imke M Veltman
Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Hum Mol Genet 14:1955-63. 2005..protease 1 gene (SENP1) on chromosome 12 and the embryonic polarity-related mesoderm development gene (MESDC2) on chromosome 15 are disrupted and fused... - MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulationY Saga
Banyu Tsukuba Research Institute Merck, Ibaraki, Japan
Development 122:2769-78. 1996..Mesp1 was mapped to the mid region of chromosome 7, near the mesodermal deficiency gene (mesd). However, a Southern hybridization study clearly showed that Mesp1 was distinctly different from mesd...
Research Grants
- Biochemical and genetic analysis of mesd functionBERNADETTE HOLDENER; Fiscal Year: 2006..of these proteins participate in general quality control, cell culture studies provide evidence that the novel MESD protein targets the LRP6 propeller...
- Bacterial Locomotion and Signal Transduction VIII Mtg.ROBERT KADNER; Fiscal Year: 2005..Conference on Bacterial Locomotion and Signal Transduction (BLAST VIII) will be held January 16-20, 2005, in Boca Raton, Florida...
- WNT SIGNALING AND BONE BIOLOGYDianqing Wu; Fiscal Year: 2009..3) Identify small molecule compounds that disrupt the LRP-Dkk interaction and Mesd- LRP interaction and determine their effects on osteogenesis...
- Regulatory Molecules in Enteric Nervous SystemALCMENE CHALAZONITIS; Fiscal Year: 2006....
- Risk Factors for Age Related Bone LossDouglas Kiel; Fiscal Year: 2006..This will advance our understanding of two of the most common chronic diseases affecting older persons. ..
- Alcohol Use and Sex in College: Developmental Change and Situational FluctuationsJennifer Maggs; Fiscal Year: 2007....
- Wnt co-receptor LRP6 turnover and cancerYonghe Li; Fiscal Year: 2010..The research proposal may lead to a novel strategy for cancer treatment. ..
- Contributions of sleep/rhythms/fatigue to "chemobrain"Sonia Ancoli Israel; Fiscal Year: 2009..The reported phenomena of chemobrain will be examined to see if it is related to the complaint of fatigue or sleep disruptions, both of which are known to contribute to decreases in cognitive functioning. ..
- Low Magnitude Mechanical Stimulation to Improve BMDDouglas Kiel; Fiscal Year: 2007..Based on strong preliminary data, this study will provide new and important information about the role of low magnitude high frequency mechanical stimulation on the skeleton. ..
- COGNITIVE BENEFITS OF TREATING SLEEP APNEA IN DEMENTIASonia Ancoli Israel; Fiscal Year: 2005..After 3 weeks, the sham group will also be switched to CPAP. Measures of neuropsychological performance will be obtained at baseline and after 3 and 6 weeks of treatment. ..
- METABOLISM OF THE VLDL RECEPTOR AND APOE RECEPTOR 2Joachim Herz; Fiscal Year: 2004..abstract_text> ..