FER

Fps/Fes and Fer are the only known members of a distinct subfamily of the non-receptor protein-tyrosine kinase family...

..Here we show that in HT-29 cells IFN-gamma transiently increased the cellular level of the tyrosine kinase Fer, whose functioning was found to be essential for the proliferation of malignant cell-lines...

Previous characterization of the nonreceptor tyrosine kinase FER identified a tight physical association with the catenin pp120 and led to the suggestion that FER may be involved in cell-cell signaling...

The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction...

..Here, we show that PA binds to the tyrosine kinase Fer and enhances its ability to phosphorylate cortactin, a protein that promotes actin polymerization...

..This residue can be phosphorylated in vitro by Fer or Fyn tyrosine kinases...

b>Fer is a nuclear and cytoplasmic intracellular tyrosine kinase. Herein we show that Fer is required for cell-cycle progression in malignant cells...

Using v-abl probes, we have identified and cloned a novel fes/fps-homologous human cDNA, which we have designated FER (pronounced "fair"). This apparently full-length cDNA of 3...

The Fer protein belongs to the fes/fps family of nontransmembrane receptor tyrosine kinases...

..F- and L-sequence alignment revealed similarities to Fer de Lance virus (FDLV) ranging from 79 to 88% on a nucleotide basis, and 94 to 99% on an amino acid basis...

..anti-PL-7, PL-12, EJ, OJ, JS, KS, ZO, YRS), anti-SRP (signal recognition particle), anti-Mas and anti-KJ, anti-Fer (eEF1), anti-Wa and anti-CADM p140...

..that is, Pg (or Cy or Pn) sophoroside-5-glucoside, acylation of anthocyanin with caffeic (Caf) or ferulic (Fer) acid was found to be important in the expression of iAGH (maltase) inhibition...

..This study was designed to evaluate the efficacy of FabAV in the neutralization of venom from 2 South American crotaline snakes: Crotalus durissus terrificus (tropical rattlesnake) and Bothrops atrox (fer-de-lance).

..Insertional inactivation of each fer gene in S...

..The FER/CIP4-homology (FCH) domain protein Cdc15p is a component of the actomyosin ring...

..Bothrops venoms cause local edema, pain, hemorrhage and necrosis. In this study, we investigated the ability of Bothrops lanceolatus venom to cause edema in rat hind paws and examined the mediators involved...

..size of low density (LDL) and high density (HDL) lipoproteins and cholesterol esterification rate in HDL plasma (FER(HDL)) are important independent predictors of coronary artery diseases (CAD)...

..Iron and riboflavin affect vitamin A utilization and photoreceptor function, respectively, and pilot data in the study population showed a high prevalence of iron and riboflavin deficiencies...

..genetic mutants [glp-1(q158), glp-4(bn2ts), plc-1(rx1), ksr-1(ku68), fog-2(q71), fem-3(q20), spe-9(hc52ts), fer-15(hc15ts)] with reduced progeny production due to various reproductive defects...

Fps/Fes and Fer are the only two members of a distinct subclass of cytoplasmic protein tyrosine kinases...

..TG) we estimated the fractional esterification rate of cholesterol in apoB lipoprotein-depleted plasma (FER(HDL)) which reflects HDL and LDL particle size distribution...

..Furthermore, carriers for these mutations might be prone to develop sporadic porphyria cutanea tarda and cardiovascular events...

..These molecules are Neuropilin-1 (NRP-1), Fer Kinase, and collapsin response mediator proteins (CRMPs), which are known to have important functions in axonal ..

..family of tyrosine protein kinases; the Fujinami poultry sarcoma/feline sarcoma (Fps/Fes) and Fes-related protein (Fer) subfamily of non-receptor proteins; and c-kit, the transmembrane tyrosine kinase receptor that belongs to the ..

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..peripheral proteins loosely attached to the outside face of the outer membrane of the wild-type and complemented (Fer+) B31 transconjugates yet was missing from this location in Fer mutants E912 and B31 and in uncomplemented (Fer-) ..

..European results of assisted reproductive techniques (ARTs) from treatments initiated during 2003 are presented in this seventh report...

..919 intracytoplasmic sperm injection (ICSI) 89 192 unclassified fertilization method 667 frozen embryo replacement (FER) 34 03 oocyte donations (OD) 4629...

..triglyceride (TGs) to HDL-cholesterol (HDL-C) and the fractional esterification rate of cholesterol in plasma depleted of apolipoprotein B (apoB)-containing lipoproteins (FER(HDL)), a functional marker of HDL and LDL particle size.

..The biological value (BV), net protein retention (NPR), protein efficiency ratio (PER) and feed efficiency ratio (FER) of the experimental food samples were significantly (p<0.05) lower than nutrend, but higher than ogi...

..The objectives of the present study were to determine the clinical effects of APC for the inferior turbinate of patients with nasal allergy and to clarify the histological changes in the mucosa after APC...

..Phosphorylated cortactin and tyrosine kinase Fer are present in the acroplaxome, thus supporting a role of this F-actin remodelling pathway during spermatid head ..

..Viperidae venoms contain vascular endothelial toxins, notably metalloproteinase hemorrhagins, but von Willebrand factor activators or vascular endothelial growth factor-type factors are more likely to have been implicated in this case...

..Here, we report that in mouse bone marrow-derived mast cells, Fer kinase is activated downstream of activated Fc epsilon RI and activated Kit receptor, and this activation is ..

..An anatomic and biomechanical bench-top basic scientific comparative analysis to determine the appropriateness of total disc replacement (TDR) in a lumbar spine with scoliotic tendencies...

..characteristics of HDL, molar and fractional esterification rates of cholesterol in plasma (MER(plasma) and FER(plasma)) and HDL (MER(HDL) and FER(HDL)) were determined in 128 children with normal HDL-C, 71 dyslipidemic, 33 ..

..Food efficiency ratio (FER, ADG/ADFI) was decreased in statin group and increased in green tea group, and the difference between these two ..

The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines...

To assess the impact of survival of cryopreservation and thawing with all blastomeres intact on the outcome of frozen embryo replacement (FER) cycles.

..Silicosis is the second commonest notified occupational disease in Hong Kong...

This study was designed to assess the value of using a gonadotrophin-releasing hormone (GnRH) agonist prior to exogenous steroid supplementation for endometrial preparation in frozen-thawed embryo replacement (FER) cycles.

..are under the control of the female gametophyte via the receptor-like serine-threonine kinase (RLK) FERONIA (FER). However, the male signaling components that control the sperm delivery remain elusive...

..several iron acquisition mechanisms, including secreted glutathione-dependent ferric reductase activity (GSH-FeR)...

..The study was conducted to elucidate any protein leakage in newborns using Evans blue dye as tracer...

..From 22 countries 538 clinics reported 258 460 cycles: IVF 125 370, ICSI 95 221, frozen embryo replacement (FER) 34 002 and oocyte donations (OD) 3867...

..Aim of the study was to determine reference values for the soluble Transferrin Receptor (sTfR) in a cross sectional population sample...

..The ratio LDL-C/HDL-C fell by 57% at week 28. Plasma LCAT activity expressed as FER was significantly enhanced by S alone (+33%), and a further increase on drug combination regimen (+58%) was ..

..also examined the relationships between soluble CAMs and the fractional esterification rate of cholesterol in HDL (FER(HDL)), particle size of LDL and lipoprotein containing apoA-I, but no apoA-II (LpA-I)...

..On the other hand, targeted disruption of the Fer kinase or pharmacological inhibition of Abl had no effect...

The conserved FER-CIP4 homology (FCH) domain is found in the pombe Cdc15 homology (PCH) protein family members, including formin-binding protein 17 (FBP17). However, the amino acid sequence homology extends beyond the FCH domain...

..The Volvox genome contains orthologs of each FER gene, indicating that the duplication of FER genes and potential diversification of function occurred prior to the ..

..equal amounts of lycopene based on levels of intake on body weight gain (BWG), feed intake, feed efficiency ratio (FER), lipid profiles, atherogenic index, and liver enzymes of hyperlipidemic rats...

..At the end of the study, body weight, food intake, feed efficiency ratio (FER), plasma glucose and cholesterol, abdominal fat pad weight, reproductive organ weight, liver weight, liver lipids, ..

..suffering from various neurological and psychiatric disorders show different levels of facial emotion recognition (FER) impairment, sometimes from the early phases of the disease...

..Six out of eight feline cell lines were susceptible to the RD-114 pseudotype virus and two cell lines (MCC and FER cells) were resistant...

..axonal collapse and neuronal death is through direct and selective interaction with the cytoplasmic tyrosine kinase Fer. Fer RNA interference effectively attenuated Sema3A-induced neurite retraction and neuronal death in cortical ..

..After the feeding period there was no significant change in weight gain, food intake and food efficiency ratio (FER)...

..We found that the Caenorhabditis elegans ortholog of the Fer nonreceptor tyrosine kinase, FRK-1, limits Wnt signaling by preventing the adhesion complex-associated ?-catenin, ..

Prior studies implicate facial emotion recognition (FER) difficulties among individuals with autism spectrum disorders (ASD); however, many investigations focus on FER accuracy alone and few examine ecological validity through links with ..

..The diet and fluid intake, body weight gain, and food efficiency ratio (FER) diminished significantly in the rats of Groups II and IV, compared with Groups I and III...

..mutations in 8 kinases, 4 of which were recurrently altered in both primary tumors and cell lines (MAP3K6, STK31, FER, and CDKL5)...

..NORTIA (NTA), a member of the MLO family originally discovered in the context of PM resistance, and FERONIA (FER), a receptor-like kinase, both control PT reception in synergids...

..with muscular dystrophy (dysferlin) and deafness (otoferlin) in humans, and infertility in Caenorhabditis elegans (Fer-1) and Drosophila (misfire), demonstrating their importance for normal cellular functioning...

..PLL) and leukaemic lymphoplasmacytic lymphoma (LL) with the combination of fludarabine, epirubicin and rituximab (FER) to improve the complete remission (CR) rate and progression-free survival (PFS)...

The primary aim of this study was to investigate facial emotion recognition (FER) in patients with somatoform disorders (SFD)...

..This study investigated impacts of chronic field exposure on gut residence time (GRT), feces elimination rate (FER), extracellular digestive protease activities and gut pH in grass shrimp Palaemonetes pugio...

To evaluate the reliability of flexion-extension ratio (FER) of lumbar erector muscle in surface EMG for the diagnosis of nonspecific chronic low back pain.

..Immunoprecipitation analyses showed that OA activated Fyn and Fer. OA promoted the association of p120 catenin/beta-catenin with Fyn and Fer and caused increased tyrosine ..

We report the association of testicular Fer, a non-receptor tyrosine kinase, with acrosome development and remodeling of the acrosome-associated acroplaxome plate during spermatid head shaping...

..Interestingly, accidents involving Bothrops lanceolatus (Fer-de-Lance) have a prothrombotic profile with necrosis and hemorrhage rarely reported...

The structure and stability of nitrosyl complexes formed in Cu-FER zeolite were investigated using a periodic DFT model...

..8 mg Cr kg(-1) had significantly improved weight gain (WG), feed efficiency ratio (FER), protein efficiency ratio (PER) and protein retention (PR)...

Peripheral membrane proteins of the Bin/amphiphysin/Rvs (BAR) and Fer-CIP4 homology-BAR (F-BAR) family participate in cellular membrane trafficking and have been shown to generate membrane tubules...

..of cholesterol by lecithin cholesterol acyltransferase (LCAT) in plasma depleted of apoB containing lipoproteins (FER(HDL))...

..European results of assisted reproductive techniques from treatments initiated during 2004 are presented in this eighth report...

..The Caenorhabditis elegans dysferlin homolog, fer-1, affects sperms development but is not known to be expressed in or have a functional roles outside of the male ..

..Two of the RLKs, FERONIA (FER) and THESEUS1 (THE1) have been previously found to inhibit cell elongation during pollen tube/synergid cell ..

..b>FER/SRN may respond to a ligand from the pollen tube...

..Among these proteins are Abl, Rak, Fes and Fer. The past year has brought significant progress both towards the elucidation of the pathways that lead to ..

..the expression of both the ferric reductase and the iron transporter genes of Strategy I plants by affecting the FER (or FER-like) transcription factor...

..O-hydroxycinnamoyl transferase, which catalyzes the transfer of ferulic acid from Fer-CoA to arabinoxylan-trisaccharide in the formation of feruloyl arabinoxylan-trisaccharide (Fer-AXX), has been found ..

We previously identified a major enhancer of the mouse ferritin H gene (FER-1) that is central to repression of the ferritin H gene by the adenovirus E1A oncogene (Tsuji, Y., Akebi, N., Lam, T. K., Nakabeppu, Y., Torti, S. V...

..The ferric reductase (FeR) from Archaeoglobus fulgidus is the first reported archaeal ferric reductase and it catalyzes the flavin-mediated ..

The subcellular localizations of the Fps/Fes and closely related Fer cytoplasmic tyrosine kinases were studied using green fluorescent protein (GFP) fusions and confocal fluorescence microscopy...

In a screen for 3T3-F442A adipocyte proteins that bind SH2 domains, we isolated a cDNA encoding Fer, a nonreceptor protein-tyrosine kinase of the Fes/Fps family that contains a functional SH2 domain...

p94(fer) and p51(ferT) are two tyrosine kinases which share identical SH2 and kinase domains but differ in their N-terminal regions...

..Subsequent analyses defined FER-1, a 37-nucleotide sequence located 4...

..Its deduced amino acid sequence shows homology to the SH2 domains of protein tyrosine kinases such as FER, and is strikingly similar to the cellular part of the v-crk oncogene product...

..Btk loci differs from that found in other described sub-families of intracellular PTKs, namely that of Src, Fes/Fer, Csk, and Abl/Arg...

..sequence homologies within the catalytic domains, the intracellular PTKs are divided into the src-family, the fes/fer- and the abl/arg-group...

..Further analyses revealed that a 37-bp region, termed FER-1, is the target of E1A-mediated repression...

..5 mol P/mol substrate. Ser81 and Thr79 are among the residues affected. On the other hand, the two tyrosyl residues of calmodulin are both phosphorylated by TPK-III, Tyr99 being preferred over Tyr138...

..No (auto)phosphorylation product(s) could be detected in TPK-IIB even if its amount, in terms of catalytic activity, was 10-fold higher than that of the others...

We have recently isolated human and rat cDNAs (designated FER and flk, respectively) which encode nonreceptor protein-tyrosine kinases which are very similar to one another and related in sequence and domain structure to the c-fps/fes ..

..evaluate if logarithm of the ratio of plasma concentration of triglycerides to HDL-cholesterol (Log[TG/HDL-C]) correlates with cholesterol esterification rates in apoB-lipoprotein-depleted plasma (FER(HDL)) and lipoprotein particle size.

..These results suggest that the purified protein acts exclusively post-synaptically...

..of hippocampus in cognition has prompted investigation into distribution of the iron storage protein ferritin (FER) in rat hippocampus...

..Here, a telephone information ser-vice meeting high quality standards can of-fer substantial support, combining the advantages of mass media with interpersonal communication...

..The chlorotic tomato fer mutant fails to activate the strategy I. It was shown previously that the fer gene is required in the root...

..We report that Fer-related kinase-1 (FRK-1), an ortholog of the mammalian non-receptor tyrosine kinase Fer, is necessary for embryonic ..

AtbHLH29 of Arabidopsis, encoding a bHLH protein, reveals a high similarity to the tomato FER which is proposed as a transcriptional regulator involved in controlling the iron deficiency responses and the iron uptake in tomato...

..A number of mutants (spe-9, fer-14, spe-13) produce cytologically normal spermatozoa, which cannot fertilize oocytes, spe-9 encodes a protein ..

..of the National Cancer Institute and summarized for patients/survivors on the website of the advocacy organization, Fer tile Hope...

..These include spe-12 and fer-1, which have already been localized to cloned DNAs; spe-8 and spe-27 which have identical phenotypes to spe-12 ; ..

..This coordinate loss of function correlates with translocation of the non-receptor tyrosine kinase Fer from its usual association in the cadherin complex of proteins to the complex of proteins associated with the ..

..These tools will ideally provide functionality for 1) detecting polymorphic regions of the genome that con- fer transcript expression differences, 2) identify polymorphic regions of the genome that impart expression differences ..

..Mutations in the worm ferlin homolog, fer-1, produce defective membrane fusion. Mutations in dysferlin cause muscular dystrophy in humans...

..l hypothes is is that a missmatch ofspcrm egg recognition molecules may lower the p robability of succcssful fer tilizatio n, resu lting in fa ilure of ill ,Iitro fertilization tria ls...

..l hypothes is is that a missmatch ofspcrm egg recognition molecules may lower the p robability of succcssful fer tilizatio n, resu lting in fa ilure of ill ,Iitro fertilization tria ls...

..neutralizing Ab, Fc receptor (FcR) activity and complement are examined by Ab transfers and using mice deficient in FeR. These experiments will determine the mechanism of Ab mediated prevention of virus reactivation in an Ab deficient ..

..Engineering mouse models in which the expression of K9 is null, is important for both reproductive biology and cancer research. ..

..Moreover, our findings will provide much needed knowledge for elucidating the molecular basis of develomental abnormalities such as congenital cardiovascular disease and other pathologies induced by disregulated actin dynamics. ..

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..Moreover, our findings will provide much needed knowledge for elucidating the molecular basis of develomental abnormalities such as congenital cardiovascular disease and other pathologies induced by disregulated actin dynamics. ..

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