DEAF1

Summary

Gene Symbol: DEAF1
Description: deformed epidermal autoregulatory factor 1 (Drosophila)
Alias: NUDR, SPN, ZMYND5, deformed epidermal autoregulatory factor 1 homolog, nuclear DEAF-1-related transcriptional regulator, suppressin, zinc finger MYND domain-containing protein 5
Species: human

Top Publications

  1. ncbi Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor
    Fanny Pilot-Storck
    UMR5239 Laboratoire de Biologie Moléculaire de la Cellule, Ecole Normale Superieure de Lyon, Lyon, France
    Mol Cell Proteomics 9:1578-93. 2010
  2. ncbi Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein
    J I Huggenvik
    Department of Physiology, Southern Illinois University School of Medicine, Carbondale 62901 6523, USA
    Mol Endocrinol 12:1619-39. 1998
  3. ncbi Changing the DNA landscape: putting a SPN on chromatin
    T Formosa
    University of Utah, Biochemistry, 20 N 1900 E RM 211, Salt Lake City, UT 84132 3201, USA
    Curr Top Microbiol Immunol 274:171-201. 2003
  4. ncbi Overview of the clinical effectiveness of positron emission tomography imaging in selected cancers
    K Facey
    Evidence Based Health Policy Consultant, Drymen, UK
    Health Technol Assess 11:iii-iv, xi-267. 2007
  5. ncbi SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta
    Usha Narayanan
    Department of Genetics, Center for Human Genetics and Program in Cell Biology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
    Hum Mol Genet 11:1785-95. 2002
  6. ncbi A visual and semi-quantitative assessment of (99m)Tc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodules
    Anna Płachcińska
    Department of Nuclear Medicine, Medical University, Łódź, Poland
    Nucl Med Rev Cent East Eur 7:143-50. 2004
  7. ncbi In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae
    Arnold Louie
    Emerging Infection and Host Defense Theme, Ordway Research Institute, 150 New Scotland Ave, Albany, NY 12208, USA
    Antimicrob Agents Chemother 51:3988-4000. 2007
  8. ncbi Solitary pulmonary nodules: comparison of multi-slice computed tomography perfusion study with vascular endothelial growth factor and microvessel density
    Rong jie Bai
    Department of Radiology, Beijing Jishuitan Hospital, Peking University, China
    Chin Med J (Engl) 122:541-7. 2009
  9. ncbi Navigation for ankle arthroscopy: anatomical study of the anterolateral portal with reference to the superficial peroneal nerve
    T Ogut
    Department of Orthopedics and Traumatology, Cerrahpasa Medical Faculty, Istanbul University, K M Pasa, 34303, Istanbul, Turkey
    Surg Radiol Anat 26:268-74. 2004
  10. ncbi Role of neurotransmitters in the central regulation of the cardiovascular system
    R B Mccall
    Cardiovascular Diseases Research, Upjohn Company, Kalamazoo, Michigan 49001
    Prog Drug Res 35:25-84. 1990

Research Grants

  1. Computerized Decision Support for Managing Lung Nodules
    Michael Gould; Fiscal Year: 2006
  2. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2009
  3. Ventilator-induced diaphragm dysfunction
    SANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010
  4. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2007
  5. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2009
  6. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael K Gould; Fiscal Year: 2010
  7. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael Gould; Fiscal Year: 2009
  8. EARLY REPEAT CT FOR EVALUATION OF SOLITARY LUNG NODULES
    David Yankelevitz; Fiscal Year: 2004
  9. DIAGNOSIS OF THE SOLITARY PULMONARY NODULE IMAGED ON CT
    MIKE MCNITT GRAY; Fiscal Year: 2003
  10. CYTOLYSIN-MEDIATED TRANSLOCATION IN S. PYOGENES VIRULENC
    Michael G Caparon; Fiscal Year: 2010

Detail Information

Publications129 found, 100 shown here

  1. ncbi Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor
    Fanny Pilot-Storck
    UMR5239 Laboratoire de Biologie Moléculaire de la Cellule, Ecole Normale Superieure de Lyon, Lyon, France
    Mol Cell Proteomics 9:1578-93. 2010
    ..In particular, we identified the deformed epidermal autoregulatory factor-1 (DEAF1) transcription factor as an interactor and in vitro substrate of GSK3A and GSK3B...
  2. ncbi Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein
    J I Huggenvik
    Department of Physiology, Southern Illinois University School of Medicine, Carbondale 62901 6523, USA
    Mol Endocrinol 12:1619-39. 1998
    ..The cDNAs encode a 59-kDa protein [nuclear DEAF-1-related (NUDR)] which shows sequence similarity to the Drosophila Deformed epidermal autoregulatory factor-1 (DEAF-1), a ..
  3. ncbi Changing the DNA landscape: putting a SPN on chromatin
    T Formosa
    University of Utah, Biochemistry, 20 N 1900 E RM 211, Salt Lake City, UT 84132 3201, USA
    Curr Top Microbiol Immunol 274:171-201. 2003
    ..1999), and CP or SPN in yeast, where it is linked in vivo to both transcription and replication (Brewster et al. 2001; Formosa et al...
  4. ncbi Overview of the clinical effectiveness of positron emission tomography imaging in selected cancers
    K Facey
    Evidence Based Health Policy Consultant, Drymen, UK
    Health Technol Assess 11:iii-iv, xi-267. 2007
    ..Management decisions relating to diagnosis, staging/restaging, recurrence, treatment response and radiotherapy (RT) planning were evaluated separately...
  5. ncbi SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta
    Usha Narayanan
    Department of Genetics, Center for Human Genetics and Program in Cell Biology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
    Hum Mol Genet 11:1785-95. 2002
    ..Snurportin1 (SPN) is the adaptor protein that recognizes both the TMG cap and importin beta...
  6. ncbi A visual and semi-quantitative assessment of (99m)Tc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodules
    Anna Płachcińska
    Department of Nuclear Medicine, Medical University, Łódź, Poland
    Nucl Med Rev Cent East Eur 7:143-50. 2004
    ....
  7. ncbi In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae
    Arnold Louie
    Emerging Infection and Host Defense Theme, Ordway Research Institute, 150 New Scotland Ave, Albany, NY 12208, USA
    Antimicrob Agents Chemother 51:3988-4000. 2007
    ..By using an in vitro pharmacodynamic infection system, a wild-type S. pneumoniae strain (Spn-058) and an isogenic strain with EP overexpression (Spn-RC2) were treated for 10 days with ciprofloxacin or ..
  8. ncbi Solitary pulmonary nodules: comparison of multi-slice computed tomography perfusion study with vascular endothelial growth factor and microvessel density
    Rong jie Bai
    Department of Radiology, Beijing Jishuitan Hospital, Peking University, China
    Chin Med J (Engl) 122:541-7. 2009
    The solitary pulmonary nodule (SPN) is one of the most common findings on chest radiographs...
  9. ncbi Navigation for ankle arthroscopy: anatomical study of the anterolateral portal with reference to the superficial peroneal nerve
    T Ogut
    Department of Orthopedics and Traumatology, Cerrahpasa Medical Faculty, Istanbul University, K M Pasa, 34303, Istanbul, Turkey
    Surg Radiol Anat 26:268-74. 2004
    ..ankle joint, in order to find easily the safest anatomical points with reference to the superficial peroneal nerve (SPN), in particular for anterolateral portal placement in ankle arthroscopy...
  10. ncbi Role of neurotransmitters in the central regulation of the cardiovascular system
    R B Mccall
    Cardiovascular Diseases Research, Upjohn Company, Kalamazoo, Michigan 49001
    Prog Drug Res 35:25-84. 1990
    ..studies indicate the importance of neurons located in the rostral ventrolateral medulla in the regulation of SPN. Indeed, this area contains medullospinal sympathoexcitatory neurons which represent the final site of integration ..
  11. ncbi Haemophilus type B meningitis in Saudi children under 5 years old
    Yagob Y Al-Mazrou
    Department of Preventive Medicine, Ministry of Health, Riyadh, Saudi Arabia
    J Trop Pediatr 50:131-6. 2004
    ..The three leading causes of meningitis were Hib (Haemophilus influenzae type B), MCM (Neisseria menigitides) and SPN (Streptococcus pneumoniae). Hib meningitis constituted 28 per cent of cases with an incidence rate of 16...
  12. ncbi Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism
    David J Riddle
    Department of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Bacteriol 192:3735-46. 2010
    ..The S. pyogenes NAD(+) glycohydrolase (SPN) is a virulence factor that has been implicated in contributing to the pathogenesis of severe infections...
  13. ncbi Somatostatin and substance P-like immunoreactivity in the auditory brainstem of the adult rat
    B Wynne
    Department of Physiology, University of Western Australia, Nedlands, Australia
    J Chem Neuroanat 12:259-66. 1997
    ..dorsal and lateral to the lateral superior olivary nucleus (LSO) and dorsal to the superior paraolivary nucleus (SPN)...
  14. ncbi Effects of sphingosine and sphingosine analogues on the free radical production by stimulated neutrophils: ESR and chemiluminescence studies
    A Mouithys-Mickalad
    Centre for the Biochemistry of Oxygen, University of Liege, and Department of Anesthesia and Intensive Care Medicine, University Hospital of Liege, Liège 4000 Belgium
    Mediators Inflamm 6:327-33. 1997
    ..By electron spin resonance spectroscopy (ESR) and chemiluminescence (CL), we studied the effects of sphingosine (SPN) and ceramide analogues on phorbol 12-myristate 13-acetate (PMA, 5x10(-7) M) stimulated PMN (6x10(6) cells)...
  15. ncbi Histamine receptor H1 and dermatopontin: new downstream targets of the vitamin D receptor
    Radhika R Pochampally
    Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Bone Miner Res 22:1338-49. 2007
    ..The roles of two genes (histamine receptor H1 and dermatopontin) as downstream targets for the VDR were confirmed by gel electromotility shift, siRNA inhibition, and chromatin immunoprecipitation assays...
  16. ncbi Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2-fluoro-2-deoxy-D-glucose avidity on positron emission tomography/computed tomography
    Rachel Bar-Shalom
    Department of Nuclear Medicine, Rambam Health Care Campus, Haifa, Israel
    Cancer 113:3213-21. 2008
    ..In the current study, the authors evaluated FDG-positron emission tomography/computed tomography (PET/CT) for the characterization of SPN in cancer patients.
  17. ncbi Glycine receptors mediate excitation of subplate neurons in neonatal rat cerebral cortex
    W Kilb
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany
    J Neurophysiol 100:698-707. 2008
    ..Subplate neurons (SPn) are involved in the construction of thalamocortical innervation, generation of oscillatory network activity, and ..
  18. ncbi Characterization of the solitary pulmonary nodule: 18F-FDG PET versus nodule-enhancement CT
    Jared A Christensen
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 187:1361-7. 2006
    ..The purpose of this study was to directly compare nodule-enhancement CT and 18F-FDG PET in the characterization of indeterminate solitary pulmonary nodules (SPNs) greater than 7 mm in size...
  19. ncbi Cefotaxime and ceftriaxone cerebrospinal fluid levels during treatment of bacterial meningitis in children
    Paul N Goldwater
    Microbiology and Infectious Diseases Department, Children, Youth and Women s Health Service, The Women s and Children s Hospital, North Adelaide, South Australia, Australia
    Int J Antimicrob Agents 26:408-11. 2005
    ..The aetiological agents included Streptococcus pneumoniae (SPn), Haemophilus influenzae type b (Hib) and Neisseria meningitidis (NMen)...
  20. ncbi Increased expression of neuronal nitric oxide synthase in bladder afferent and spinal neurons following spinal cord injury
    M A Vizzard
    College of Medicine, University of Vermont, Department of Neurology 0540, USA
    Dev Neurosci 19:232-46. 1997
    ..SCI) were examined in bladder afferent and spinal neurons in the region of the sacral parasympathetic nucleus (SPN) in the L6-S1 spinal segments...
  21. ncbi Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms
    S M M de Castro
    Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands
    World J Surg 31:1130-5. 2007
    ..Solid-pseudopapillary neoplasms (SPNs) of the pancreas are increasingly diagnosed, but the exact surgical management in terms of extent of the resection is not well defined...
  22. ncbi Transneuronal labeling of neurons in the adult rat central nervous system following inoculation of pseudorabies virus into the colon
    M A Vizzard
    University of Vermont, College of Medicine, Department of Neurology, Burlington 05405, USA
    Cell Tissue Res 299:9-26. 2000
    ..005) greater numbers of PRV-IR cells were present in the region of the sacral parasympathetic nucleus (SPN) of the S1 spinal segment compared to that of the L6 segment...
  23. ncbi Cross-talk between snurportin1 subdomains
    Jason K Ospina
    Department of Genetics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 4955, USA
    Mol Biol Cell 16:4660-71. 2005
    ..and a trimethylguanosine (TMG) cap, the RNPs are transported into the nucleus via the import adaptor snurportin1 (SPN) and the import receptor importin-beta...
  24. ncbi Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39
    Skye M Barendt
    Department of Biology, Indiana University Bloomington, Bloomington, IN 47405, USA
    J Bacteriol 193:2290-300. 2011
    ..In addition, we characterized deletion mutations in nonessential genes of unknown function in the WalRK(Spn) two-component system regulon, which also contains the essential pcsB cell division gene...
  25. ncbi Expression of corticotropin-releasing factor and CRF receptors in micturition pathways after cyclophosphamide-induced cystitis
    Jennifer LaBerge
    Dept of Anatomy, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Regul Integr Comp Physiol 291:R692-703. 2006
    ..These studies examined the expression of CRF in the urinary bladder and lumbosacral sacral parasympathetic nucleus (SPN) in response to cyclophosphamide (CYP)-induced cystitis (4 h, 48 h, or chronic) in rats...
  26. ncbi Immune evasion genes from filarial nematodes
    R M Maizels
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Int J Parasitol 31:889-98. 2001
    ..the major T cell-stimulating antigen from the microfilarial stage as a serpin (serine protease inhibitor), Bm-SPN-2...
  27. ncbi Endometrium and ovarian cancer synchronous to endometriosis--a retrospective study of our experience of 7 years
    Ioannis Grammatikakis
    Lito Maternity Hospital, Department of Gynecology 7 13 Mouson Street, 11524, Paleo Psychiko, Greece
    J Med Life 3:76-9. 2010
    ..The objective of this study is to explore the epidemiology of synchronous neoplasms (SPN) in women with severe endometriosis.
  28. ncbi [Imaging features of lung carcinoma, pulmonary tuberculoma, and inflammatory pseudotumor on helical incremental dynamic CT scan--a report of 44 cases]
    Shi ting Feng
    Department of Radiology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong 510080, P R China
    Ai Zheng 25:348-51. 2006
    Lung carcinoma, pulmonary tuberculoma, and inflammatory pesudotumor are the most common solitary pulmonary nodules (SPN). Computed tomography (CT) is the major diagnostic examination of them...
  29. ncbi Underivatized polyamine analysis in plant samples by ion pair LC coupled with electrospray tandem mass spectrometry
    Jose Sanchez-Lopez
    Biochemistry and Plant Biotechnology Laboratory, Department of Ciencias Agrarias y del Medio Natural, Universitat Jaume I, Castellón 12071, Spain
    Plant Physiol Biochem 47:592-8. 2009
    ..multiresidue method for putrescine (Put), 1,3-diaminopropane (DAP), l-ornithine, spermidine (Spd) and spermine (Spn) measurements in plant samples...
  30. ncbi Effect of nepadutant, a neurokinin 2 tachykinin receptor antagonist, on immediate-early gene expression after trinitrobenzenesulfonic acid-induced colitis in the rat
    Lori A Birder
    Department of Medicine Laboratory of Epithelial Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Pharmacol Exp Ther 304:272-6. 2003
    ..dorsal horn, dorsal commissure (DCM; laminae X above the central canal), and the sacral parasympathetic nucleus (SPN, laminae V-VII)...
  31. ncbi A sarcoglycan-dystroglycan complex anchors Dp116 and utrophin in the peripheral nervous system
    M Imamura
    Department of Cell Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi cho, Kodaira, Tokyo 187 8502, Japan
    Hum Mol Genet 9:3091-100. 2000
    ..subcomplexes, the dystroglycan and the sarcoglycan (SG) complexes, and a small membrane protein termed sarcospan (SPN). The SG complex consists of four transmembrane glycoproteins, alpha-SG, beta-SG, gamma-SG and delta-SG...
  32. ncbi Solitary pulmonary nodules caused by Mycobacterium tuberculosis and Mycobacterium avium complex
    Cho Rom Hahm
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, Republic of Korea
    Lung 188:25-31. 2010
    ..Median SPN size was 22 mm...
  33. ncbi The greater Denver Latino Cancer Prevention/Control Network. Prevention and research through a community-based approach
    Estevan Flores
    Latino a Research and Policy Center, University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80204, USA
    Cancer 107:2034-42. 2006
    ..The Special Population Network (SPN) adapted and revised a clinical trials education outreach module that reached Network community partners...
  34. ncbi Efficacy of 99mTc-EDDA/HYNIC-TOC scintigraphy in differential diagnosis of solitary pulmonary nodules
    Anna Płachcińska
    Department of Nuclear Medicine, Medical University, Łódź, Poland
    Cancer Biother Radiopharm 19:613-20. 2004
    Fifty consecutive patients with solitary pulmonary nodules (SPN) on chest radiographs were studied scintigraphically after the administration of a somatostatin analog 99mTc-EDDA/HYNIC-TOC...
  35. ncbi Cytologic features of benign solitary pulmonary nodules with radiologic correlation and diagnostic pitfalls: a report of six cases
    Shahidul Islam
    Cytopathology Section, Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, the Ottawa Hospital and the University of Ottawa, Ontario, Canada
    Acta Cytol 53:201-10. 2009
    The solitary pulmonary nodule (SPN) is a common radiologic abnormality often detected incidentally. The majority of SPNs represent benign processes, including granulotmatous inflammation, bronchogenic cysts and hamartomata...
  36. ncbi The relationship between solitary pulmonary nodules and bronchi: multi-slice CT-pathological correlation
    J W Qiang
    Department of Radiology, Jinshan Hospital of Fudan University, Shanghai, China
    Clin Radiol 59:1121-7. 2004
    To investigate the relationship between solitary pulmonary nodules (SPN) and bronchi and its value in predicting the nature of the SPN.
  37. ncbi New patterns in the otopathogens causing acute otitis media six to eight years after introduction of pneumococcal conjugate vaccine
    Janet R Casey
    Department of Pediatrics, University of Rochester, Rochester, NY, USA
    Pediatr Infect Dis J 29:304-9. 2010
    ....
  38. ncbi Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1
    Kyungmin Hahm
    Division of Hematology Oncology, Department of Pediatrics, Children s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Mol Cell Biol 24:2074-82. 2004
    ..The transcription factor Deaf-1/NUDR has been identified as one partner protein of LMO4...
  39. ncbi Superficial peroneal nerve/peroneus brevis muscle biopsy in vasculitic neuropathy
    M P Collins
    Department of Neurology, The Ohio State University College of Medicine, Columbus 43210, USA
    Neurology 55:636-43. 2000
    To determine the sensitivity and specificity of superficial peroneal nerve (SPN)/peroneus brevis muscle (PBM) biopsy in a cohort of patients with suspected peripheral nerve vasculitis.
  40. ncbi A cadaver study on preserving peroneal nerves during ankle arthroscopy
    Hulya Ucerler
    Ege University Medicine Faculty, Department of Anatomy, 35100 Bornova, Izmir, Turkey
    Foot Ankle Int 28:1172-8. 2007
    ..By understanding the anatomy of the superficial peroneal nerve (SPN) and deep peroneal nerve (DPN) the risk of nerve injury can be minimized.
  41. ncbi Validation of two models to estimate the probability of malignancy in patients with solitary pulmonary nodules
    E M Schultz
    Stanford School of Medicine, Stanford, CA 94305, USA
    Thorax 63:335-41. 2008
    Effective strategies for managing patients with solitary pulmonary nodules (SPN) depend critically on the pre-test probability of malignancy.
  42. ncbi [Value of [18F]-FDG-PET/CT as a predictor of cancer in solitary pulmonary nodule]
    Rafael de Castro Martins
    Escola Médica de Pós Graduação, Pontificia Universidade Catolica do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    J Bras Pneumol 34:473-80. 2008
    To determine the diagnostic accuracy of positron emission tomography/computed tomography (PET/CT) using fluorine-18-deoxyglucose ([18F]-FDG) for the evaluation of a solitary pulmonary nodule (SPN).
  43. ncbi The paraventricular nucleus of the hypothalamus sends efferents to the spinal cord of the rat that closely appose sympathetic preganglionic neurones projecting to the stellate ganglion
    R N Ranson
    Department of Physiology, The Medical School, University of Birmingham, Edgbaston, UK
    Exp Brain Res 120:164-72. 1998
    ..and in particular those axonal projections that appear to be contiguous with sympathetic preganglionic neurones (SPN) projecting to the stellate ganglion have been studied...
  44. ncbi Neurochemistry of nerve fibers apposing sympathetic preganglionic neurons activated by sustained hypotension
    Jane B Minson
    Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University of South Australia, Bedford Park, Adelaide, South Australia 5042, Australia
    J Comp Neurol 449:307-18. 2002
    Sympathetic preganglionic neurons (SPN) in rat spinal cord were activated by the reflex stimulation of bulbospinal sympathetic neuronal pathways after a nitroprusside-induced hypotension...
  45. ncbi The effects and mechanism of saponins of Panax notoginseng on glucose metabolism in 3T3-L1 cells
    Jane J Y Kim
    Department of Medical and Molecular Biosciences, University of Technology, Sydney, NSW 2007, Australia
    Am J Chin Med 37:1179-89. 2009
    This study was carried out to determine the effect of saponins of Panax notoginseng (SPN), a naturally occurring cardiovascular agent, on: (1) glucose uptake, (2) GLUT4 translocation and (3) glycogen synthesis in 3T3-L1 adipocytes...
  46. ncbi Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary nodule
    Catherine Lejeune
    Faculte de Medecine, Dijon, France
    Eur J Health Econ 6:203-14. 2005
    ..The base case was defined as a 65-year-old male smoker with a 2-cm SPN and an associated high risk of malignancy of 43%...
  47. ncbi Cloning and direct sequencing from lambda cDNA libraries using the polymerase chain reaction: suppressin and the vasopressin receptor as models
    R D LeBoeuf
    Department of Physiology and Biophysics, University of Alabama, Birmingham 35294 0005
    Neth J Med 39:295-305. 1991
    ..using the polymerase chain reaction (PCR) to screen a lambda gt11 pituitary cDNA library for cDNAs encoding suppressin, a putative anti-proliferative protein, and a putative vasopressin receptor is described...
  48. ncbi Dynamic enhancement patterns of solitary pulmonary nodules at multi-detector row CT and correlation with vascular endothelial growth factor and microvessel density
    Nan Chuan Jiang
    Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China
    Ai Zheng 28:164-9. 2009
    ..assess dynamic enhancement patterns of SPNs detected with multi-detector row computed tomography (MDCT), correlate SPN manifestations of MDCT to the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD),..
  49. ncbi Segregation of met-enkephalin from vesicular acetylcholine transporter and choline acetyltransferase in sympathetic preganglionic varicosities mostly lacking synaptophysin and synaptotagmin
    C Sámano
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, 3er Circuito Exterior, Ciudad Universitaria, Mexico, DF 04510, Mexico
    Neuroscience 163:180-9. 2009
    Sympathetic preganglionic neurons (SPN) coexpress the acetylcholine (ACh)-synthesizing enzyme choline acetyltransferase and different peptides in their cell bodies, but can express them independently in separate varicosities, indicating ..
  50. ncbi Does the availability of positron emission tomography modify diagnostic strategies for solitary pulmonary nodules? An observational study in France
    Irawati Lemonnier
    Nancy University, France
    BMC Cancer 9:139. 2009
    ....
  51. ncbi Computer aided characterization of the solitary pulmonary nodule using volumetric and contrast enhancement features
    Sumit K Shah
    Department of Radiology, David Geffen School of Medicine at the University of California Los Angeles, Thoracic Imaging Research Group, 924 Westwood Blvd Suite 650, Box 957319, Los Angeles, CA 90095 7319, USA
    Acad Radiol 12:1310-9. 2005
    ....
  52. ncbi Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6
    Alison R Rhoades
    Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Mol Cell Biol 24:3907-17. 2004
    The Saccharomyces cerevisiae Spt16/Cdc68, Pob3, and Nhp6 proteins (SPN or yFACT) bind to and alter nucleosomes in vitro, providing a potential explanation for their importance in both transcription and replication in vivo...
  53. ncbi Actions of the anaesthetic Saffan on rat sympathetic preganglionic neurones in vitro
    M F Nolan
    Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Scotland
    Br J Pharmacol 121:324-30. 1997
    ..4. Changes in the properties of SPN action potentials were also observed...
  54. ncbi Evaluation of secondary protein nutrients as a substitute for soybean meal in diets for beef steers and meat goats
    S R Freeman
    Department of Animal Science, North Carolina State University, Raleigh 27695, USA
    J Anim Sci 86:146-58. 2008
    ..This meal, called secondary protein nutrients (SPN), is high in protein (45% CP), fat (28% crude fat), and minerals...
  55. ncbi Comparison of suction catheter versus forceps biopsy for sampling of solitary pulmonary nodules guided by electromagnetic navigational bronchoscopy
    Ralf Eberhardt
    Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg gGmbH, Heidelberg, Germany
    Respiration 79:54-60. 2010
    ..Electromagnetic navigation has been approved for use as an adjunct to standard bronchoscopy. The diagnostic yield varies depending on the size of the lesion and successful navigation to the lesion...
  56. ncbi Preliminary study on the correlation between grading and histology of solitary pulmonary nodules and contrast enhancement and [18F]fluorodeoxyglucose standardised uptake value after evaluation by dynamic multiphase CT and PET/CT
    Salvatore Cappabianca
    Department of Clinical Internal Medicine F Magrassi L Lanzara, Science Section of Radiology, Second University of Studies of Naples, Naples, Italy
    J Clin Pathol 64:114-9. 2011
    ..To evaluate whether the histology and grading of solitary pulmonary nodules (SPNs) correlated with the results of dynamic multiphase multidetector CT (MDCT) and the [(18)F]fluorodeoxyglucose standardised uptake value (SUV) in 30 patients...
  57. ncbi Accuracy of PET/CT in characterization of solitary pulmonary lesions
    Shanna K Kim
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6942, USA
    J Nucl Med 48:214-20. 2007
    ..There is extensive literature on the use of PET and CT in the characterization of a solitary pulmonary nodule (SPN)...
  58. ncbi MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans
    Nancy N Huang
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 129:747-59. 2002
    ..RNA interference of MEX-6, a CCCH zinc-finger protein, or SPN-4, an RNA recognition motif protein, causes PAL-1 to be expressed in all four blastomeres starting at the four-cell ..
  59. ncbi Anatomy of synaptic circuits controlling the activity of sympathetic preganglionic neurons
    Ida J Llewellyn-Smith
    Cardiovascular Medicine, Physiology and Centre for Neuroscience, Flinders University, Bedford Park, South Australia, Australia
    J Chem Neuroanat 38:231-9. 2009
    Sympathetic preganglionic neurons (SPN) are critical links in the sympathetic neural circuitry that controls every organ in the body...
  60. ncbi [Fusion of pulmonary scintigraphy with Tc99m-depreotide imaging with CT scan in recognizing solitary pulmonary nodule]
    Norbert Szalus
    Wojskowy Instytut Medyczny w Warszawie, CSK MON, Zakład Medycyny Nuklearnej
    Pol Merkur Lekarski 25:330-4. 2008
    ..One of them is solitary pulmonary nodule (SPN) scintigraphy using 99mTc-depreotide...
  61. ncbi Diagnosis and management of cystic lesions of the pancreas
    Niraj Jani
    Department of Medicine, Saint Agnes Hospital, Baltimore, MD 21229, USA
    Diagn Ther Endosc 2011:478913. 2011
    ..the five most common diagnoses-pancreatic pseudocyst, serous cystic neoplasm (SCN), solid pseudopapillary neoplasm (SPN), mucinous cystic neoplasm (MCN), and intraductal mucinous papillary neoplasm (IPMN)-is likely the correct one ..
  62. ncbi Single-institution experience with solid pseudopapillary neoplasm of the pancreas
    Daniel Ansari
    Department of Surgery, Clinical Sciences Lund, Lund University, Sweden
    Scand J Gastroenterol 46:1492-7. 2011
    Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare clinical entity. The objective of this study was to review a single institution's experience with this uncommon tumor, as well as review the literature.
  63. ncbi Dynamic integration of subplate neurons into the cortical barrel field circuitry during postnatal development in the Golli-tau-eGFP (GTE) mouse
    Maria Carmen Piñon
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
    J Physiol 587:1903-15. 2009
    ..GTE) transgenic mouse the reporter gene expression is largely confined to the layer of subplate neurons (SPn), providing an opportunity to study their intracortical and extracortical projections...
  64. ncbi Information capacity of stochastic pooling networks is achieved by discrete inputs
    Mark D McDonnell
    Institute for Telecommunications Research, University of South Australia, SA 5095, Australia
    Phys Rev E Stat Nonlin Soft Matter Phys 79:041107. 2009
    Stochastic pooling networks (SPN) are sensor networks where multiple sensors make independently noisy and compressed measurements of the same information source, which are combined via pooling...
  65. ncbi The evaluation and management of the solitary pulmonary nodule
    A O Soubani
    Division of Pulmonary, Allergy, Critical Care and Sleep, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Postgrad Med J 84:459-66. 2008
    ..Radiological features of the SPN based on chest CT with high resolution cuts are critical in differentiating between benign or malignant lesions...
  66. ncbi Electrophysiological, pharmacological and molecular profile of the transient outward rectifying conductance in rat sympathetic preganglionic neurons in vitro
    A D Whyment
    Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK
    Neuroscience 178:68-81. 2011
    Transient outward rectifying conductances or A-like conductances in sympathetic preganglionic neurons (SPN) are prolonged, lasting for hundreds of milliseconds to seconds and are thought to play a key role in the regulation of SPN firing ..
  67. ncbi Variation in neighbouring genes of the dopaminergic and serotonergic systems affects feather pecking behaviour of laying hens
    K Flisikowski
    Lehrstuhl fuer Tierzucht, Technische Universitaet Muenchen, Hochfeldweg 1, 85354 Freising Weihenstephan, Germany
    Anim Genet 40:192-9. 2009
    ..Linkage disequilibrium (LD) extends into a neighbouring gene encoding deformed epidermal autoregulatory factor 1 (DEAF1)...
  68. ncbi Heterogeneity of membrane properties in sympathetic preganglionic neurons of neonatal mice: evidence of four subpopulations in the intermediolateral nucleus
    Amanda Zimmerman
    Department of Biomedical Engineering, School of Medicine, Emory University Georgia Institute of Technology, 615 Michael St, Atlanta, GA 30322, USA
    J Neurophysiol 103:490-8. 2010
    ..The intermediolateral column (IML) has the highest number and density of SPNs and, within this region, SPN somas are found in distinct clusters within thoracic and upper lumbar spinal segments...
  69. ncbi Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional series
    Sushanth Reddy
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Am Coll Surg 208:950-7; discussion 957-9. 2009
    Solid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors with malignant potential. Clinicopathologic characteristics and outcomes of patients with SPN were reviewed.
  70. ncbi Localization and cellular amounts of the WalRKJ (VicRKX) two-component regulatory system proteins in serotype 2 Streptococcus pneumoniae
    Kyle J Wayne
    Department of Biology, Indiana University Bloomington, Bloomington, Indiana 47405, USA
    J Bacteriol 192:4388-94. 2010
    ..Phosphorylated WalR (VicR) of the major human respiratory pathogen Streptococcus pneumoniae (WalR(Spn)) positively regulates transcription of several surface virulence genes and, most critically, pcsB, which encodes ..
  71. ncbi Direct immunofluoresence in vasculitic neuropathy: specificity of vascular immune deposits
    Michael P Collins
    Department of Neurology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, Wisconsin 53226, USA
    Muscle Nerve 42:62-9. 2010
    In suspected vasculitic neuropathy, vasculitis is demonstrated in only 30% of superficial peroneal nerve (SPN)/peroneus brevis muscle (PBM) specimens. Pathologic predictors of vasculitis are thus needed for non-diagnostic cases...
  72. ncbi [Streptococcus pneumoniae serotype replacement in nasopharyngeal colonization in children vaccinated with PCV7 in Mexico]
    Luz Elena Espinosa-de Los Monteros
    Hospital General Manuel Gea Gonzalez, Mexico, DF, Mexico
    Salud Publica Mex 52:4-13. 2010
    To assess the impact of pneumococcal conjugate vaccine (PCV7) immunization on pneumococcal nasopharyngeal colonization with S. pneumoniae (SPN).
  73. ncbi Streptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin O
    N Goundo Magassa
    Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
    EMBO Rep 11:400-5. 2010
    ..pyogenes nicotinamide adenine dinucleotide-glycohydrolase (SPN) into the host cell cytosol, resulting in the death of the host cell...
  74. ncbi Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis
    Joydeep Ghosh
    Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 285:5683-94. 2010
    The gram-positive pathogen Streptococcus pyogenes injects a beta-NAD(+) glycohydrolase (SPN) into the cytosol of an infected host cell using the cytolysin-mediated translocation pathway...
  75. ncbi First report of the cattle tick Rhipicephalus microplus resistant to ivermectin in Mexico
    L C Perez-Cogollo
    Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autonoma de Yucatan, Yucatan, Mexico
    Vet Parasitol 168:165-9. 2010
    ..with ticks, Rhipicephalus microplus, thought to be resistant to ivermectin in Yucatan, Mexico were studied (SFDO, SPN, LUADY). Each field-population was collected and tested twice several months apart...
  76. ncbi E-cadherin/beta-catenin and CD10: a limited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solid pseudopapillary neoplasm of the pancreas on endoscopic ultrasound-guided fine-needle aspirates of the pancreas
    Holly Burford
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Am J Clin Pathol 132:831-9. 2009
    Pancreatic endocrine neoplasm (PEN) and solid pseudopapillary neoplasm of the pancreas (SPN) frequently pose diagnostic challenges...
  77. ncbi Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker
    Lisa M Kaminskas
    Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Campus, 381 Royal Pde, Parkville, Vic, 3052, Australia
    J Control Release 152:241-8. 2011
    ..5 PEGylated polylysine dendrimers comprising an outer generation of l-lysine or succinimyldipropyldiamine (SPN) and containing doxorubicin (DOX) linked through an acid labile 4-(hydrazinosulfonyl) benzoic acid (HSBA) linker ..
  78. ncbi Solid pseudopapillary neoplasms of the pancreas: a multi-institutional study of 21 patients
    Jesus M Matos
    Department of Surgery, Indiana University School of Medicine, Indianapolis, 46202, USA
    J Surg Res 157:e137-42. 2009
    Solid pseudopapillary neoplasms of the pancreas (SPN) account for less than 1% of all pancreatic tumors...
  79. ncbi Chronic social defeat downregulates the 5-HT1A receptor but not Freud-1 or NUDR in the rat prefrontal cortex
    Niamh Kieran
    Department of Psychiatry and Human Behavior and Center for Psychiatric Neuroscience, University of Mississippi Medical Center, School of Medicine, Jackson, MS 39216, USA
    Neurosci Lett 469:380-4. 2010
    ..five prime repressor element under dual repression (Freud-1) and nuclear-deformed epidermal autoregulatory factor (NUDR/Deaf-1) have been previously found to be the repressors for 5-HT1A in the serotonergic raphe neurons, and are also ..
  80. ncbi Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism
    Rainer J Egli
    RMS Foundation, Bettlach, Switzerland
    Arthritis Rheum 60:2055-64. 2009
    ....
  81. ncbi Nasopharyngeal carriage of S. pneumoniae among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 14:1025-33. 2009
    To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal.
  82. ncbi Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle
    Amir Bitan
    Department of Life Sciences and National Institute for Biotechnology, Negev, Ben Gurion University, Beer Sheva 84105, Israel
    Mol Cell Biol 30:496-507. 2010
    ..markers for studying the importance of properly polarized MTs to bristle axial growth are Ik2 and Spindle-F (Spn-F), since mutations in spn-F and ik2 affect bristle development...
  83. ncbi Newborn vitamin A supplementation does not affect nasopharyngeal carriage of Streptococcus pneumoniae in Bangladeshi infants at age 3 months
    Christian L Coles
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Nutr 141:1907-11. 2011
    Nasopharyngeal (NP) carriage of S. pneumoniae (Spn) is a risk factor for pneumococcal disease and its transmission...
  84. ncbi Laparoendoscopic single-site nephrectomy: initial clinical experience in children
    Gino J Vricella
    Department of Urology, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5046, USA
    J Endourol 24:1957-61. 2010
    ..To present the initial clinical experience in children undergoing unilateral and bilateral laparoendoscopic single-site nephrectomy...
  85. ncbi Nucleus raphe obscurus (nRO) regulation of anorectal motility in rats
    G M Holmes
    Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, Columbus 43210, USA
    Brain Res 759:197-204. 1997
    ..cells within the intermediolateral (IML) cell column of the thoracic cord and the sacral parasympathetic nucleus (SPN)...
  86. ncbi Analysis models to assess cost effectiveness of the four strategies for the work-up of solitary pulmonary nodules
    Yoshito Tsushima
    Department of Radiology, Motojima General Hospital, Ohta, Gunma, Japan
    Med Sci Monit 10:MT65-72. 2004
    ..fluorodeoxyglucose positron emission tomography (FDG-PET) in the investigation of solitary pulmonary nodules (SPN), which are discovered on screening chest radiographs, and to determine the cost-effectiveness of these modalities.
  87. ncbi Components of the reelin signaling pathway are expressed in the spinal cord
    Yee Ping Yip
    Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Comp Neurol 470:210-9. 2004
    ..Previous work showed that Reelin also affects the positioning of sympathetic preganglionic neurons (SPN) in the spinal cord (Yip et al. [2000] Proc Natl Acad Sci USA 97:8612-8616)...
  88. ncbi Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco
    Sameer Jhavar
    Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Oral Oncol 40:84-91. 2004
    ..multiple primary neoplasms (MPN) were compared with 28 age and sex matched patients with a single primary neoplasm (SPN) for various environmental factors (form of tobacco use, alcohol, radiotherapy for index cancer) and genetic ..
  89. ncbi Orexin-immunoreactive inputs to rat sympathetic preganglionic neurons
    I J Llewellyn-Smith
    Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University, Bedford Park, SA 5042, Australia
    Neurosci Lett 351:115-9. 2003
    ..Seeking anatomical evidence for direct effects of orexin on sympathetic preganglionic neurons (SPN), we used immunohistochemistry to study the relationships between orexin-IR axons and SPN identified by ..
  90. ncbi The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis
    Uri Abdu
    Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    Genetics 165:197-204. 2003
    In Drosophila, mutations in double-strand DNA break (DSB) repair enzymes, such as spn-B, activate a meiotic checkpoint leading to dorsal-ventral patterning defects in the egg and an abnormal appearance of the oocyte nucleus...
  91. ncbi Ectopic sympathetic preganglionic neurons maintain proper connectivity in the reeler mutant mouse
    Y P Yip
    Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Neuroscience 118:439-50. 2003
    The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal...
  92. ncbi [Usefulness of video-assisted thoracoscopy for the diagnosis of solitary pulmonary nodules]
    M Congregado Loscertales
    Servicio de Cirugía General y Torácica, Hospital Universitario Virgen Macarena, Sevilla, Spain
    Arch Bronconeumol 38:415-20. 2002
    Various approaches are used for the diagnosis and treatment of solitary pulmonary nodules (SPN) of unknown origin...
  93. ncbi ERD as an index of anticipatory attention? Effects of stimulus degradation
    Marcel C M Bastiaansen
    Cooperation Centre Tilburg and Eindhoven Universities, Tilburg, The Netherlands
    Psychophysiology 39:16-28. 2002
    Previous research has suggested that the stimulus-preceding negativity (SPN) is largely independent of stimulus modality...
  94. ncbi Management of solitary pulmonary nodules: how do thoracic computed tomography and guided fine needle biopsy influence clinical decisions?
    D R Baldwin
    Department of Respiratory Medicine, City Hospital, Nottingham NG5 1PB, UK
    Thorax 57:817-22. 2002
    ..techniques on clinical decision making has not been quantified, especially for small solitary pulmonary nodules (SPN) where the probability of malignancy is lower...
  95. ncbi Solitary pulmonary nodules: potential role of dynamic MR imaging in management initial experience
    Yoshiharu Ohno
    Department of Radiology, Kobe University Graduate School of Medicine, 7 5 2 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Radiology 224:503-11. 2002
    ..To evaluate the utility of dynamic magnetic resonance (MR) imaging in the management of solitary pulmonary nodules (SPNs)...
  96. ncbi GABA in the control of sympathetic preganglionic neurons
    Ida J Llewellyn-Smith
    Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University, Bedford Park, South Australia, Australia
    Clin Exp Pharmacol Physiol 29:507-13. 2002
    ..are critical for controlling the activity of most central neurons, including sympathetic preganglionic neurons (SPN), the spinal cord neurons involved in controlling blood pressure and other autonomic functions. 2...
  97. ncbi The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity
    Eleanor Y M Sum
    Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, Melbourne, Victoria 3050, Australia
    J Biol Chem 277:7849-56. 2002
    ..These findings reveal a novel complex between BRCA1, LMO4, and CtIP and indicate a role for LMO4 as a repressor of BRCA1 activity in breast tissue...
  98. ncbi Stimulus-preceding negativity induced by fear: a manifestation of affective anticipation
    K B Böcker
    Department of Psychopharmacology and Rudolf Magnus Institute of Neuroscience, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, Utrecht, The Netherlands
    Int J Psychophysiol 43:77-90. 2001
    The Stimulus-Preceding Negativity (SPN), a slow cortical potential, has been studied in relation to anticipatory attention...
  99. ncbi Diagnostic relevance of procalcitonin, IL-6, and sICAM-1 in the prediction of infected necrosis in acute pancreatitis
    Y Mandi
    Department of Medical Microbiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Int J Pancreatol 28:41-9. 2000
    ..The aim of the study was to analyze the clinical value of procalcitonin (PCT) for the prediction of infected necrosis, in comparison with interleukin-6 (IL-6) and sICAM 1...
  100. ncbi Local collateral projections from the medial superior olive to the superior paraolivary nucleus in the gerbil
    N Kuwabara
    Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Health Sciences Center, Louisville, KY 40292, USA
    Brain Res 846:59-71. 1999
    ..the MSO as the latter passed through a dorsally neighboring periolivary nucleus, the superior paraolivary nucleus (SPN), toward the ipsilateral inferior colliculus (IC), their traditionally accepted target...

Research Grants67

  1. Computerized Decision Support for Managing Lung Nodules
    Michael Gould; Fiscal Year: 2006
    ..To achieve this overall goal, we have three specific aims: (1) to develop ALCHEMIST-SPN, an interactive decision support system for management of patients with solitary pulmonary nodules, by linking a ..
  2. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2009
    ..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours before ..
  3. Ventilator-induced diaphragm dysfunction
    SANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010
    ..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years;(b) same gender;(c) receives neuromuscular blocking agents <3 hours before ..
  4. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2007
    ..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age ¿5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours ..
  5. Ventilator-induced diaphragm dysfunction
    Sanford Levine; Fiscal Year: 2009
    ..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours before ..
  6. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael K Gould; Fiscal Year: 2010
    ..Subsequently, we developed ALCHEMIST-SPN, a web-based decision support system for managing patients with solitary pulmonary nodules (SPN), by linking a ..
  7. Evaluation of Computerized Decision Support for Managing Lung Nodules
    Michael Gould; Fiscal Year: 2009
    ..Subsequently, we developed ALCHEMIST-SPN, a web-based decision support system for managing patients with solitary pulmonary nodules (SPN), by linking a ..
  8. EARLY REPEAT CT FOR EVALUATION OF SOLITARY LUNG NODULES
    David Yankelevitz; Fiscal Year: 2004
    The solitary pulmonary nodule (SPN) is a common and challenging problem, with approximately 150,000 new SPNs being detected each year. The most common etiology of SPN remains lung cancer...
  9. DIAGNOSIS OF THE SOLITARY PULMONARY NODULE IMAGED ON CT
    MIKE MCNITT GRAY; Fiscal Year: 2003
    ..The applicants proposed to develop a methodology to provide a more comprehensive examination of the SPN by coupling CT acquisition techniques (including investigating the use of contrast enhanced spiral scans) with ..
  10. CYTOLYSIN-MEDIATED TRANSLOCATION IN S. PYOGENES VIRULENC
    Michael G Caparon; Fiscal Year: 2010
    ..pyogenes NAD-glycohydrolase (SPN) across the host cell membrane and into its cytosol...
  11. Bacteria-Mucin Interactions at the Ocular Surface
    Ilene K Gipson; Fiscal Year: 2010
    ..g., outbreaks of bacterial conjunctivitis from non-encapsulated Streptococcus pneumoniae (SPN), occur without evidence of ocular surface damage...
  12. STREPTOCOCCUS PNEUMONIAE ADHERENCE AND OTITIS MEDIA PATH
    Thomas Demaria; Fiscal Year: 2004
    ..Streptococcus pneumoniae (Spn), is one of the foremost human pathogens and is the primary nasopharynx, the initial event in the induction of OM ..
  13. Deaf1 isoforms control changes in PTA expression in the NOD PLN during T1D pathog
    CHARLES GARRISON FATHMAN; Fiscal Year: 2010
    ..Our laboratory recently identified Deaf1 as a transcriptional regulator of PTA gene expression in peripheral lymph nodes...
  14. Complement in S.pneumoniae otitis Media
    Hua Hua Tong; Fiscal Year: 2009
    ..Streptococcus pneumoniae (Spn) is one of the primary pathogens of OM...
  15. Complement in S.pneumoniae otitis Media
    Hua Hua Tong; Fiscal Year: 2010
    ..Streptococcus pneumoniae (Spn) is one of the primary pathogens of OM...
  16. ATECAR: Asian Training, Education on Cancer & Research
    Grace Ma; Fiscal Year: 2007
    ..The proposal goals and objectives are based on 5-years of ATECAR-SPN experience with Asian communities in this region and are supported by an elaborate system of experienced community-..
  17. Cytolysin-mediated translocation in S.pyogenes virulence
    Michael Caparon; Fiscal Year: 2009
    ..pyogenes NAD-glycohydrolase (SPN) into the host cell cytosol...
  18. NUDR--A Potential Tumor Suppressor of Childhood Cancers
    Jodi Huggenvik; Fiscal Year: 2005
    b>NUDR is a mammalian transcription factor with homology to Drosophila DEAF-1, a developmental cofactor of Hox and homeodomain proteins...
  19. Cytolysin-mediated translocation in S. pyogenes virulence
    Michael Caparon; Fiscal Year: 2007
    ..pyogenes NAD-glycohydrolase (SPN) into the host cell cytosol...
  20. RNA recognition by maternal gene silencers in nematodes
    SEAN PATRICK RYDER; Fiscal Year: 2010
    ..we focus on the RNA-binding proteins that pattern Notch/glp-1 expression in the embryo (MEX-3, MEX-5, POS-1, SPN-4, and GLD-1)...
  21. Patient Navigation for CRC Screening with Low-Income Minorities
    William H Redd; Fiscal Year: 2010
    ..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
  22. Patient Navigation for CRC Screening with Low-Income Minorities
    William Redd; Fiscal Year: 2007
    ..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
  23. Patient Navigation for CRC Screening with Low-Income Minorities
    William H Redd; Fiscal Year: 2010
    ..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
  24. Biochemical & Genetic Analysis of Yeast SPN
    Timothy Formosa; Fiscal Year: 2005
    ..Experiments in this proposal explore the nature of the changes induced in nucleosomes by Sptl6-Pob3-Nhp6 (SPN), with the goal of understanding how SPN changes the structure of this fundamental unit of genomic packaging...
  25. Acquision of Appllied Biosystems 3730 DNA Analyzer for the DNA Sciences Core
    Yongde Bao; Fiscal Year: 2007
    ..following three important fronts: 1) DNA sequencing, 2) Genotyping including microsatilite and SNP analyses with Applied Biosystems SpaPshot , and 3) higher throughput SPN screening with Applied Biosystems oligo48-plex SNPlex analysis.