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Genomes and Genes | DEAF1SummaryGene Symbol: DEAF1 Description: deformed epidermal autoregulatory factor 1 (Drosophila) Alias: NUDR, SPN, ZMYND5, deformed epidermal autoregulatory factor 1 homolog, nuclear DEAF-1-related transcriptional regulator, suppressin, zinc finger MYND domain-containing protein 5 Species: human Top Publications
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Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactorFanny Pilot-Storck
UMR5239 Laboratoire de Biologie Moléculaire de la Cellule, Ecole Normale Superieure de Lyon, Lyon, France
Mol Cell Proteomics 9:1578-93. 2010..In particular, we identified the deformed epidermal autoregulatory factor-1 (DEAF1) transcription factor as an interactor and in vitro substrate of GSK3A and GSK3B...
Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator proteinJ I Huggenvik
Department of Physiology, Southern Illinois University School of Medicine, Carbondale 62901 6523, USA
Mol Endocrinol 12:1619-39. 1998..The cDNAs encode a 59-kDa protein [nuclear DEAF-1-related (NUDR)] which shows sequence similarity to the Drosophila Deformed epidermal autoregulatory factor-1 (DEAF-1), a ..
Changing the DNA landscape: putting a SPN on chromatinT Formosa
University of Utah, Biochemistry, 20 N 1900 E RM 211, Salt Lake City, UT 84132 3201, USA
Curr Top Microbiol Immunol 274:171-201. 2003..1999), and CP or SPN in yeast, where it is linked in vivo to both transcription and replication (Brewster et al. 2001; Formosa et al...
Overview of the clinical effectiveness of positron emission tomography imaging in selected cancersK Facey
Evidence Based Health Policy Consultant, Drymen, UK
Health Technol Assess 11:iii-iv, xi-267. 2007..Management decisions relating to diagnosis, staging/restaging, recurrence, treatment response and radiotherapy (RT) planning were evaluated separately...
SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin betaUsha Narayanan
Department of Genetics, Center for Human Genetics and Program in Cell Biology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
Hum Mol Genet 11:1785-95. 2002..Snurportin1 (SPN) is the adaptor protein that recognizes both the TMG cap and importin beta...
A visual and semi-quantitative assessment of (99m)Tc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodulesAnna Płachcińska
Department of Nuclear Medicine, Medical University, Łódź, Poland
Nucl Med Rev Cent East Eur 7:143-50. 2004....
In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniaeArnold Louie
Emerging Infection and Host Defense Theme, Ordway Research Institute, 150 New Scotland Ave, Albany, NY 12208, USA
Antimicrob Agents Chemother 51:3988-4000. 2007..By using an in vitro pharmacodynamic infection system, a wild-type S. pneumoniae strain (Spn-058) and an isogenic strain with EP overexpression (Spn-RC2) were treated for 10 days with ciprofloxacin or ..
Solitary pulmonary nodules: comparison of multi-slice computed tomography perfusion study with vascular endothelial growth factor and microvessel densityRong jie Bai
Department of Radiology, Beijing Jishuitan Hospital, Peking University, China
Chin Med J (Engl) 122:541-7. 2009The solitary pulmonary nodule (SPN) is one of the most common findings on chest radiographs...
Navigation for ankle arthroscopy: anatomical study of the anterolateral portal with reference to the superficial peroneal nerveT Ogut
Department of Orthopedics and Traumatology, Cerrahpasa Medical Faculty, Istanbul University, K M Pasa, 34303, Istanbul, Turkey
Surg Radiol Anat 26:268-74. 2004..ankle joint, in order to find easily the safest anatomical points with reference to the superficial peroneal nerve (SPN), in particular for anterolateral portal placement in ankle arthroscopy...
Role of neurotransmitters in the central regulation of the cardiovascular systemR B Mccall
Cardiovascular Diseases Research, Upjohn Company, Kalamazoo, Michigan 49001
Prog Drug Res 35:25-84. 1990..studies indicate the importance of neurons located in the rostral ventrolateral medulla in the regulation of SPN. Indeed, this area contains medullospinal sympathoexcitatory neurons which represent the final site of integration ..
Haemophilus type B meningitis in Saudi children under 5 years oldYagob Y Al-Mazrou
Department of Preventive Medicine, Ministry of Health, Riyadh, Saudi Arabia
J Trop Pediatr 50:131-6. 2004..The three leading causes of meningitis were Hib (Haemophilus influenzae type B), MCM (Neisseria menigitides) and SPN (Streptococcus pneumoniae). Hib meningitis constituted 28 per cent of cases with an incidence rate of 16...
Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropismDavid J Riddle
Department of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Bacteriol 192:3735-46. 2010..The S. pyogenes NAD(+) glycohydrolase (SPN) is a virulence factor that has been implicated in contributing to the pathogenesis of severe infections...
Somatostatin and substance P-like immunoreactivity in the auditory brainstem of the adult ratB Wynne
Department of Physiology, University of Western Australia, Nedlands, Australia
J Chem Neuroanat 12:259-66. 1997..dorsal and lateral to the lateral superior olivary nucleus (LSO) and dorsal to the superior paraolivary nucleus (SPN)...
Effects of sphingosine and sphingosine analogues on the free radical production by stimulated neutrophils: ESR and chemiluminescence studiesA Mouithys-Mickalad
Centre for the Biochemistry of Oxygen, University of Liege, and Department of Anesthesia and Intensive Care Medicine, University Hospital of Liege, Liège 4000 Belgium
Mediators Inflamm 6:327-33. 1997..By electron spin resonance spectroscopy (ESR) and chemiluminescence (CL), we studied the effects of sphingosine (SPN) and ceramide analogues on phorbol 12-myristate 13-acetate (PMA, 5x10(-7) M) stimulated PMN (6x10(6) cells)...
Histamine receptor H1 and dermatopontin: new downstream targets of the vitamin D receptorRadhika R Pochampally
Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
J Bone Miner Res 22:1338-49. 2007..The roles of two genes (histamine receptor H1 and dermatopontin) as downstream targets for the VDR were confirmed by gel electromotility shift, siRNA inhibition, and chromatin immunoprecipitation assays...
Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2-fluoro-2-deoxy-D-glucose avidity on positron emission tomography/computed tomographyRachel Bar-Shalom
Department of Nuclear Medicine, Rambam Health Care Campus, Haifa, Israel
Cancer 113:3213-21. 2008..In the current study, the authors evaluated FDG-positron emission tomography/computed tomography (PET/CT) for the characterization of SPN in cancer patients.
Glycine receptors mediate excitation of subplate neurons in neonatal rat cerebral cortexW Kilb
Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany
J Neurophysiol 100:698-707. 2008..Subplate neurons (SPn) are involved in the construction of thalamocortical innervation, generation of oscillatory network activity, and ..
Characterization of the solitary pulmonary nodule: 18F-FDG PET versus nodule-enhancement CTJared A Christensen
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
AJR Am J Roentgenol 187:1361-7. 2006..The purpose of this study was to directly compare nodule-enhancement CT and 18F-FDG PET in the characterization of indeterminate solitary pulmonary nodules (SPNs) greater than 7 mm in size...
Cefotaxime and ceftriaxone cerebrospinal fluid levels during treatment of bacterial meningitis in childrenPaul N Goldwater
Microbiology and Infectious Diseases Department, Children, Youth and Women s Health Service, The Women s and Children s Hospital, North Adelaide, South Australia, Australia
Int J Antimicrob Agents 26:408-11. 2005..The aetiological agents included Streptococcus pneumoniae (SPn), Haemophilus influenzae type b (Hib) and Neisseria meningitidis (NMen)...
Increased expression of neuronal nitric oxide synthase in bladder afferent and spinal neurons following spinal cord injuryM A Vizzard
College of Medicine, University of Vermont, Department of Neurology 0540, USA
Dev Neurosci 19:232-46. 1997..SCI) were examined in bladder afferent and spinal neurons in the region of the sacral parasympathetic nucleus (SPN) in the L6-S1 spinal segments...
Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasmsS M M de Castro
Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands
World J Surg 31:1130-5. 2007..Solid-pseudopapillary neoplasms (SPNs) of the pancreas are increasingly diagnosed, but the exact surgical management in terms of extent of the resection is not well defined...
Transneuronal labeling of neurons in the adult rat central nervous system following inoculation of pseudorabies virus into the colonM A Vizzard
University of Vermont, College of Medicine, Department of Neurology, Burlington 05405, USA
Cell Tissue Res 299:9-26. 2000..005) greater numbers of PRV-IR cells were present in the region of the sacral parasympathetic nucleus (SPN) of the S1 spinal segment compared to that of the L6 segment...
Cross-talk between snurportin1 subdomainsJason K Ospina
Department of Genetics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 4955, USA
Mol Biol Cell 16:4660-71. 2005..and a trimethylguanosine (TMG) cap, the RNPs are transported into the nucleus via the import adaptor snurportin1 (SPN) and the import receptor importin-beta...
Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39Skye M Barendt
Department of Biology, Indiana University Bloomington, Bloomington, IN 47405, USA
J Bacteriol 193:2290-300. 2011..In addition, we characterized deletion mutations in nonessential genes of unknown function in the WalRK(Spn) two-component system regulon, which also contains the essential pcsB cell division gene...
Expression of corticotropin-releasing factor and CRF receptors in micturition pathways after cyclophosphamide-induced cystitisJennifer LaBerge
Dept of Anatomy, University of Vermont College of Medicine, Burlington, VT 05405, USA
Am J Physiol Regul Integr Comp Physiol 291:R692-703. 2006..These studies examined the expression of CRF in the urinary bladder and lumbosacral sacral parasympathetic nucleus (SPN) in response to cyclophosphamide (CYP)-induced cystitis (4 h, 48 h, or chronic) in rats...
Immune evasion genes from filarial nematodesR M Maizels
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
Int J Parasitol 31:889-98. 2001..the major T cell-stimulating antigen from the microfilarial stage as a serpin (serine protease inhibitor), Bm-SPN-2...
Endometrium and ovarian cancer synchronous to endometriosis--a retrospective study of our experience of 7 yearsIoannis Grammatikakis
Lito Maternity Hospital, Department of Gynecology 7 13 Mouson Street, 11524, Paleo Psychiko, Greece
J Med Life 3:76-9. 2010..The objective of this study is to explore the epidemiology of synchronous neoplasms (SPN) in women with severe endometriosis.
[Imaging features of lung carcinoma, pulmonary tuberculoma, and inflammatory pseudotumor on helical incremental dynamic CT scan--a report of 44 cases]Shi ting Feng
Department of Radiology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong 510080, P R China
Ai Zheng 25:348-51. 2006Lung carcinoma, pulmonary tuberculoma, and inflammatory pesudotumor are the most common solitary pulmonary nodules (SPN). Computed tomography (CT) is the major diagnostic examination of them...
Underivatized polyamine analysis in plant samples by ion pair LC coupled with electrospray tandem mass spectrometryJose Sanchez-Lopez
Biochemistry and Plant Biotechnology Laboratory, Department of Ciencias Agrarias y del Medio Natural, Universitat Jaume I, Castellón 12071, Spain
Plant Physiol Biochem 47:592-8. 2009..multiresidue method for putrescine (Put), 1,3-diaminopropane (DAP), l-ornithine, spermidine (Spd) and spermine (Spn) measurements in plant samples...
Effect of nepadutant, a neurokinin 2 tachykinin receptor antagonist, on immediate-early gene expression after trinitrobenzenesulfonic acid-induced colitis in the ratLori A Birder
Department of Medicine Laboratory of Epithelial Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Pharmacol Exp Ther 304:272-6. 2003..dorsal horn, dorsal commissure (DCM; laminae X above the central canal), and the sacral parasympathetic nucleus (SPN, laminae V-VII)...
A sarcoglycan-dystroglycan complex anchors Dp116 and utrophin in the peripheral nervous systemM Imamura
Department of Cell Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi cho, Kodaira, Tokyo 187 8502, Japan
Hum Mol Genet 9:3091-100. 2000..subcomplexes, the dystroglycan and the sarcoglycan (SG) complexes, and a small membrane protein termed sarcospan (SPN). The SG complex consists of four transmembrane glycoproteins, alpha-SG, beta-SG, gamma-SG and delta-SG...
Solitary pulmonary nodules caused by Mycobacterium tuberculosis and Mycobacterium avium complexCho Rom Hahm
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, Republic of Korea
Lung 188:25-31. 2010..Median SPN size was 22 mm...
The greater Denver Latino Cancer Prevention/Control Network. Prevention and research through a community-based approachEstevan Flores
Latino a Research and Policy Center, University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80204, USA
Cancer 107:2034-42. 2006..The Special Population Network (SPN) adapted and revised a clinical trials education outreach module that reached Network community partners...
Efficacy of 99mTc-EDDA/HYNIC-TOC scintigraphy in differential diagnosis of solitary pulmonary nodulesAnna Płachcińska
Department of Nuclear Medicine, Medical University, Łódź, Poland
Cancer Biother Radiopharm 19:613-20. 2004Fifty consecutive patients with solitary pulmonary nodules (SPN) on chest radiographs were studied scintigraphically after the administration of a somatostatin analog 99mTc-EDDA/HYNIC-TOC...
Cytologic features of benign solitary pulmonary nodules with radiologic correlation and diagnostic pitfalls: a report of six casesShahidul Islam
Cytopathology Section, Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, the Ottawa Hospital and the University of Ottawa, Ontario, Canada
Acta Cytol 53:201-10. 2009The solitary pulmonary nodule (SPN) is a common radiologic abnormality often detected incidentally. The majority of SPNs represent benign processes, including granulotmatous inflammation, bronchogenic cysts and hamartomata...
The relationship between solitary pulmonary nodules and bronchi: multi-slice CT-pathological correlationJ W Qiang
Department of Radiology, Jinshan Hospital of Fudan University, Shanghai, China
Clin Radiol 59:1121-7. 2004To investigate the relationship between solitary pulmonary nodules (SPN) and bronchi and its value in predicting the nature of the SPN.
New patterns in the otopathogens causing acute otitis media six to eight years after introduction of pneumococcal conjugate vaccineJanet R Casey
Department of Pediatrics, University of Rochester, Rochester, NY, USA
Pediatr Infect Dis J 29:304-9. 2010....
Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1Kyungmin Hahm
Division of Hematology Oncology, Department of Pediatrics, Children s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
Mol Cell Biol 24:2074-82. 2004..The transcription factor Deaf-1/NUDR has been identified as one partner protein of LMO4...
Superficial peroneal nerve/peroneus brevis muscle biopsy in vasculitic neuropathyM P Collins
Department of Neurology, The Ohio State University College of Medicine, Columbus 43210, USA
Neurology 55:636-43. 2000To determine the sensitivity and specificity of superficial peroneal nerve (SPN)/peroneus brevis muscle (PBM) biopsy in a cohort of patients with suspected peripheral nerve vasculitis.
A cadaver study on preserving peroneal nerves during ankle arthroscopyHulya Ucerler
Ege University Medicine Faculty, Department of Anatomy, 35100 Bornova, Izmir, Turkey
Foot Ankle Int 28:1172-8. 2007..By understanding the anatomy of the superficial peroneal nerve (SPN) and deep peroneal nerve (DPN) the risk of nerve injury can be minimized.
Validation of two models to estimate the probability of malignancy in patients with solitary pulmonary nodulesE M Schultz
Stanford School of Medicine, Stanford, CA 94305, USA
Thorax 63:335-41. 2008Effective strategies for managing patients with solitary pulmonary nodules (SPN) depend critically on the pre-test probability of malignancy.
[Value of [18F]-FDG-PET/CT as a predictor of cancer in solitary pulmonary nodule]Rafael de Castro Martins
Escola Médica de Pós Graduação, Pontificia Universidade Catolica do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
J Bras Pneumol 34:473-80. 2008To determine the diagnostic accuracy of positron emission tomography/computed tomography (PET/CT) using fluorine-18-deoxyglucose ([18F]-FDG) for the evaluation of a solitary pulmonary nodule (SPN).
The paraventricular nucleus of the hypothalamus sends efferents to the spinal cord of the rat that closely appose sympathetic preganglionic neurones projecting to the stellate ganglionR N Ranson
Department of Physiology, The Medical School, University of Birmingham, Edgbaston, UK
Exp Brain Res 120:164-72. 1998..and in particular those axonal projections that appear to be contiguous with sympathetic preganglionic neurones (SPN) projecting to the stellate ganglion have been studied...
Neurochemistry of nerve fibers apposing sympathetic preganglionic neurons activated by sustained hypotensionJane B Minson
Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University of South Australia, Bedford Park, Adelaide, South Australia 5042, Australia
J Comp Neurol 449:307-18. 2002Sympathetic preganglionic neurons (SPN) in rat spinal cord were activated by the reflex stimulation of bulbospinal sympathetic neuronal pathways after a nitroprusside-induced hypotension...
The effects and mechanism of saponins of Panax notoginseng on glucose metabolism in 3T3-L1 cellsJane J Y Kim
Department of Medical and Molecular Biosciences, University of Technology, Sydney, NSW 2007, Australia
Am J Chin Med 37:1179-89. 2009This study was carried out to determine the effect of saponins of Panax notoginseng (SPN), a naturally occurring cardiovascular agent, on: (1) glucose uptake, (2) GLUT4 translocation and (3) glycogen synthesis in 3T3-L1 adipocytes...
Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary noduleCatherine Lejeune
Faculte de Medecine, Dijon, France
Eur J Health Econ 6:203-14. 2005..The base case was defined as a 65-year-old male smoker with a 2-cm SPN and an associated high risk of malignancy of 43%...
Cloning and direct sequencing from lambda cDNA libraries using the polymerase chain reaction: suppressin and the vasopressin receptor as modelsR D LeBoeuf
Department of Physiology and Biophysics, University of Alabama, Birmingham 35294 0005
Neth J Med 39:295-305. 1991..using the polymerase chain reaction (PCR) to screen a lambda gt11 pituitary cDNA library for cDNAs encoding suppressin, a putative anti-proliferative protein, and a putative vasopressin receptor is described...
Dynamic enhancement patterns of solitary pulmonary nodules at multi-detector row CT and correlation with vascular endothelial growth factor and microvessel densityNan Chuan Jiang
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China
Ai Zheng 28:164-9. 2009..assess dynamic enhancement patterns of SPNs detected with multi-detector row computed tomography (MDCT), correlate SPN manifestations of MDCT to the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD),..
Segregation of met-enkephalin from vesicular acetylcholine transporter and choline acetyltransferase in sympathetic preganglionic varicosities mostly lacking synaptophysin and synaptotagminC Sámano
Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, 3er Circuito Exterior, Ciudad Universitaria, Mexico, DF 04510, Mexico
Neuroscience 163:180-9. 2009Sympathetic preganglionic neurons (SPN) coexpress the acetylcholine (ACh)-synthesizing enzyme choline acetyltransferase and different peptides in their cell bodies, but can express them independently in separate varicosities, indicating ..
Does the availability of positron emission tomography modify diagnostic strategies for solitary pulmonary nodules? An observational study in FranceIrawati Lemonnier
Nancy University, France
BMC Cancer 9:139. 2009....
Computer aided characterization of the solitary pulmonary nodule using volumetric and contrast enhancement featuresSumit K Shah
Department of Radiology, David Geffen School of Medicine at the University of California Los Angeles, Thoracic Imaging Research Group, 924 Westwood Blvd Suite 650, Box 957319, Los Angeles, CA 90095 7319, USA
Acad Radiol 12:1310-9. 2005....
Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6Alison R Rhoades
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Mol Cell Biol 24:3907-17. 2004The Saccharomyces cerevisiae Spt16/Cdc68, Pob3, and Nhp6 proteins (SPN or yFACT) bind to and alter nucleosomes in vitro, providing a potential explanation for their importance in both transcription and replication in vivo...
Actions of the anaesthetic Saffan on rat sympathetic preganglionic neurones in vitroM F Nolan
Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Scotland
Br J Pharmacol 121:324-30. 1997..4. Changes in the properties of SPN action potentials were also observed...
Evaluation of secondary protein nutrients as a substitute for soybean meal in diets for beef steers and meat goatsS R Freeman
Department of Animal Science, North Carolina State University, Raleigh 27695, USA
J Anim Sci 86:146-58. 2008..This meal, called secondary protein nutrients (SPN), is high in protein (45% CP), fat (28% crude fat), and minerals...
Comparison of suction catheter versus forceps biopsy for sampling of solitary pulmonary nodules guided by electromagnetic navigational bronchoscopyRalf Eberhardt
Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg gGmbH, Heidelberg, Germany
Respiration 79:54-60. 2010..Electromagnetic navigation has been approved for use as an adjunct to standard bronchoscopy. The diagnostic yield varies depending on the size of the lesion and successful navigation to the lesion...
Preliminary study on the correlation between grading and histology of solitary pulmonary nodules and contrast enhancement and [18F]fluorodeoxyglucose standardised uptake value after evaluation by dynamic multiphase CT and PET/CTSalvatore Cappabianca
Department of Clinical Internal Medicine F Magrassi L Lanzara, Science Section of Radiology, Second University of Studies of Naples, Naples, Italy
J Clin Pathol 64:114-9. 2011..To evaluate whether the histology and grading of solitary pulmonary nodules (SPNs) correlated with the results of dynamic multiphase multidetector CT (MDCT) and the [(18)F]fluorodeoxyglucose standardised uptake value (SUV) in 30 patients...
Accuracy of PET/CT in characterization of solitary pulmonary lesionsShanna K Kim
Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6942, USA
J Nucl Med 48:214-20. 2007..There is extensive literature on the use of PET and CT in the characterization of a solitary pulmonary nodule (SPN)...
MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegansNancy N Huang
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Development 129:747-59. 2002..RNA interference of MEX-6, a CCCH zinc-finger protein, or SPN-4, an RNA recognition motif protein, causes PAL-1 to be expressed in all four blastomeres starting at the four-cell ..
Anatomy of synaptic circuits controlling the activity of sympathetic preganglionic neuronsIda J Llewellyn-Smith
Cardiovascular Medicine, Physiology and Centre for Neuroscience, Flinders University, Bedford Park, South Australia, Australia
J Chem Neuroanat 38:231-9. 2009Sympathetic preganglionic neurons (SPN) are critical links in the sympathetic neural circuitry that controls every organ in the body...
[Fusion of pulmonary scintigraphy with Tc99m-depreotide imaging with CT scan in recognizing solitary pulmonary nodule]Norbert Szalus
Wojskowy Instytut Medyczny w Warszawie, CSK MON, Zakład Medycyny Nuklearnej
Pol Merkur Lekarski 25:330-4. 2008..One of them is solitary pulmonary nodule (SPN) scintigraphy using 99mTc-depreotide...
Diagnosis and management of cystic lesions of the pancreasNiraj Jani
Department of Medicine, Saint Agnes Hospital, Baltimore, MD 21229, USA
Diagn Ther Endosc 2011:478913. 2011..the five most common diagnoses-pancreatic pseudocyst, serous cystic neoplasm (SCN), solid pseudopapillary neoplasm (SPN), mucinous cystic neoplasm (MCN), and intraductal mucinous papillary neoplasm (IPMN)-is likely the correct one ..
Single-institution experience with solid pseudopapillary neoplasm of the pancreasDaniel Ansari
Department of Surgery, Clinical Sciences Lund, Lund University, Sweden
Scand J Gastroenterol 46:1492-7. 2011Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare clinical entity. The objective of this study was to review a single institution's experience with this uncommon tumor, as well as review the literature.
Dynamic integration of subplate neurons into the cortical barrel field circuitry during postnatal development in the Golli-tau-eGFP (GTE) mouseMaria Carmen Piñon
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
J Physiol 587:1903-15. 2009..GTE) transgenic mouse the reporter gene expression is largely confined to the layer of subplate neurons (SPn), providing an opportunity to study their intracortical and extracortical projections...
Information capacity of stochastic pooling networks is achieved by discrete inputsMark D McDonnell
Institute for Telecommunications Research, University of South Australia, SA 5095, Australia
Phys Rev E Stat Nonlin Soft Matter Phys 79:041107. 2009Stochastic pooling networks (SPN) are sensor networks where multiple sensors make independently noisy and compressed measurements of the same information source, which are combined via pooling...
The evaluation and management of the solitary pulmonary noduleA O Soubani
Division of Pulmonary, Allergy, Critical Care and Sleep, Wayne State University School of Medicine, Detroit, MI 48201, USA
Postgrad Med J 84:459-66. 2008..Radiological features of the SPN based on chest CT with high resolution cuts are critical in differentiating between benign or malignant lesions...
Electrophysiological, pharmacological and molecular profile of the transient outward rectifying conductance in rat sympathetic preganglionic neurons in vitroA D Whyment
Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK
Neuroscience 178:68-81. 2011Transient outward rectifying conductances or A-like conductances in sympathetic preganglionic neurons (SPN) are prolonged, lasting for hundreds of milliseconds to seconds and are thought to play a key role in the regulation of SPN firing ..
Variation in neighbouring genes of the dopaminergic and serotonergic systems affects feather pecking behaviour of laying hensK Flisikowski
Lehrstuhl fuer Tierzucht, Technische Universitaet Muenchen, Hochfeldweg 1, 85354 Freising Weihenstephan, Germany
Anim Genet 40:192-9. 2009..Linkage disequilibrium (LD) extends into a neighbouring gene encoding deformed epidermal autoregulatory factor 1 (DEAF1)...
Heterogeneity of membrane properties in sympathetic preganglionic neurons of neonatal mice: evidence of four subpopulations in the intermediolateral nucleusAmanda Zimmerman
Department of Biomedical Engineering, School of Medicine, Emory University Georgia Institute of Technology, 615 Michael St, Atlanta, GA 30322, USA
J Neurophysiol 103:490-8. 2010..The intermediolateral column (IML) has the highest number and density of SPNs and, within this region, SPN somas are found in distinct clusters within thoracic and upper lumbar spinal segments...
Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional seriesSushanth Reddy
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Am Coll Surg 208:950-7; discussion 957-9. 2009Solid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors with malignant potential. Clinicopathologic characteristics and outcomes of patients with SPN were reviewed.
Localization and cellular amounts of the WalRKJ (VicRKX) two-component regulatory system proteins in serotype 2 Streptococcus pneumoniaeKyle J Wayne
Department of Biology, Indiana University Bloomington, Bloomington, Indiana 47405, USA
J Bacteriol 192:4388-94. 2010..Phosphorylated WalR (VicR) of the major human respiratory pathogen Streptococcus pneumoniae (WalR(Spn)) positively regulates transcription of several surface virulence genes and, most critically, pcsB, which encodes ..
Direct immunofluoresence in vasculitic neuropathy: specificity of vascular immune depositsMichael P Collins
Department of Neurology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, Wisconsin 53226, USA
Muscle Nerve 42:62-9. 2010In suspected vasculitic neuropathy, vasculitis is demonstrated in only 30% of superficial peroneal nerve (SPN)/peroneus brevis muscle (PBM) specimens. Pathologic predictors of vasculitis are thus needed for non-diagnostic cases...
[Streptococcus pneumoniae serotype replacement in nasopharyngeal colonization in children vaccinated with PCV7 in Mexico]Luz Elena Espinosa-de Los Monteros
Hospital General Manuel Gea Gonzalez, Mexico, DF, Mexico
Salud Publica Mex 52:4-13. 2010To assess the impact of pneumococcal conjugate vaccine (PCV7) immunization on pneumococcal nasopharyngeal colonization with S. pneumoniae (SPN).
Streptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin ON Goundo Magassa
Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
EMBO Rep 11:400-5. 2010..pyogenes nicotinamide adenine dinucleotide-glycohydrolase (SPN) into the host cell cytosol, resulting in the death of the host cell...
Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesisJoydeep Ghosh
Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 285:5683-94. 2010The gram-positive pathogen Streptococcus pyogenes injects a beta-NAD(+) glycohydrolase (SPN) into the cytosol of an infected host cell using the cytolysin-mediated translocation pathway...
First report of the cattle tick Rhipicephalus microplus resistant to ivermectin in MexicoL C Perez-Cogollo
Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autonoma de Yucatan, Yucatan, Mexico
Vet Parasitol 168:165-9. 2010..with ticks, Rhipicephalus microplus, thought to be resistant to ivermectin in Yucatan, Mexico were studied (SFDO, SPN, LUADY). Each field-population was collected and tested twice several months apart...
E-cadherin/beta-catenin and CD10: a limited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solid pseudopapillary neoplasm of the pancreas on endoscopic ultrasound-guided fine-needle aspirates of the pancreasHolly Burford
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Am J Clin Pathol 132:831-9. 2009Pancreatic endocrine neoplasm (PEN) and solid pseudopapillary neoplasm of the pancreas (SPN) frequently pose diagnostic challenges...
Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linkerLisa M Kaminskas
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Campus, 381 Royal Pde, Parkville, Vic, 3052, Australia
J Control Release 152:241-8. 2011..5 PEGylated polylysine dendrimers comprising an outer generation of l-lysine or succinimyldipropyldiamine (SPN) and containing doxorubicin (DOX) linked through an acid labile 4-(hydrazinosulfonyl) benzoic acid (HSBA) linker ..
Solid pseudopapillary neoplasms of the pancreas: a multi-institutional study of 21 patientsJesus M Matos
Department of Surgery, Indiana University School of Medicine, Indianapolis, 46202, USA
J Surg Res 157:e137-42. 2009Solid pseudopapillary neoplasms of the pancreas (SPN) account for less than 1% of all pancreatic tumors...
Chronic social defeat downregulates the 5-HT1A receptor but not Freud-1 or NUDR in the rat prefrontal cortexNiamh Kieran
Department of Psychiatry and Human Behavior and Center for Psychiatric Neuroscience, University of Mississippi Medical Center, School of Medicine, Jackson, MS 39216, USA
Neurosci Lett 469:380-4. 2010..five prime repressor element under dual repression (Freud-1) and nuclear-deformed epidermal autoregulatory factor (NUDR/Deaf-1) have been previously found to be the repressors for 5-HT1A in the serotonergic raphe neurons, and are also ..
Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphismRainer J Egli
RMS Foundation, Bettlach, Switzerland
Arthritis Rheum 60:2055-64. 2009....
Nasopharyngeal carriage of S. pneumoniae among young children in rural NepalChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Trop Med Int Health 14:1025-33. 2009To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal.
Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristleAmir Bitan
Department of Life Sciences and National Institute for Biotechnology, Negev, Ben Gurion University, Beer Sheva 84105, Israel
Mol Cell Biol 30:496-507. 2010..markers for studying the importance of properly polarized MTs to bristle axial growth are Ik2 and Spindle-F (Spn-F), since mutations in spn-F and ik2 affect bristle development...
Newborn vitamin A supplementation does not affect nasopharyngeal carriage of Streptococcus pneumoniae in Bangladeshi infants at age 3 monthsChristian L Coles
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
J Nutr 141:1907-11. 2011Nasopharyngeal (NP) carriage of S. pneumoniae (Spn) is a risk factor for pneumococcal disease and its transmission...
Laparoendoscopic single-site nephrectomy: initial clinical experience in childrenGino J Vricella
Department of Urology, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5046, USA
J Endourol 24:1957-61. 2010..To present the initial clinical experience in children undergoing unilateral and bilateral laparoendoscopic single-site nephrectomy...
Nucleus raphe obscurus (nRO) regulation of anorectal motility in ratsG M Holmes
Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, Columbus 43210, USA
Brain Res 759:197-204. 1997..cells within the intermediolateral (IML) cell column of the thoracic cord and the sacral parasympathetic nucleus (SPN)...
Analysis models to assess cost effectiveness of the four strategies for the work-up of solitary pulmonary nodulesYoshito Tsushima
Department of Radiology, Motojima General Hospital, Ohta, Gunma, Japan
Med Sci Monit 10:MT65-72. 2004..fluorodeoxyglucose positron emission tomography (FDG-PET) in the investigation of solitary pulmonary nodules (SPN), which are discovered on screening chest radiographs, and to determine the cost-effectiveness of these modalities.
Components of the reelin signaling pathway are expressed in the spinal cordYee Ping Yip
Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Comp Neurol 470:210-9. 2004..Previous work showed that Reelin also affects the positioning of sympathetic preganglionic neurons (SPN) in the spinal cord (Yip et al. [2000] Proc Natl Acad Sci USA 97:8612-8616)...
Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobaccoSameer Jhavar
Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India
Oral Oncol 40:84-91. 2004..multiple primary neoplasms (MPN) were compared with 28 age and sex matched patients with a single primary neoplasm (SPN) for various environmental factors (form of tobacco use, alcohol, radiotherapy for index cancer) and genetic ..
Orexin-immunoreactive inputs to rat sympathetic preganglionic neuronsI J Llewellyn-Smith
Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University, Bedford Park, SA 5042, Australia
Neurosci Lett 351:115-9. 2003..Seeking anatomical evidence for direct effects of orexin on sympathetic preganglionic neurons (SPN), we used immunohistochemistry to study the relationships between orexin-IR axons and SPN identified by ..
The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosisUri Abdu
Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
Genetics 165:197-204. 2003In Drosophila, mutations in double-strand DNA break (DSB) repair enzymes, such as spn-B, activate a meiotic checkpoint leading to dorsal-ventral patterning defects in the egg and an abnormal appearance of the oocyte nucleus...
Ectopic sympathetic preganglionic neurons maintain proper connectivity in the reeler mutant mouseY P Yip
Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Neuroscience 118:439-50. 2003The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal...
[Usefulness of video-assisted thoracoscopy for the diagnosis of solitary pulmonary nodules]M Congregado Loscertales
Servicio de Cirugía General y Torácica, Hospital Universitario Virgen Macarena, Sevilla, Spain
Arch Bronconeumol 38:415-20. 2002Various approaches are used for the diagnosis and treatment of solitary pulmonary nodules (SPN) of unknown origin...
ERD as an index of anticipatory attention? Effects of stimulus degradationMarcel C M Bastiaansen
Cooperation Centre Tilburg and Eindhoven Universities, Tilburg, The Netherlands
Psychophysiology 39:16-28. 2002Previous research has suggested that the stimulus-preceding negativity (SPN) is largely independent of stimulus modality...
Management of solitary pulmonary nodules: how do thoracic computed tomography and guided fine needle biopsy influence clinical decisions?D R Baldwin
Department of Respiratory Medicine, City Hospital, Nottingham NG5 1PB, UK
Thorax 57:817-22. 2002..techniques on clinical decision making has not been quantified, especially for small solitary pulmonary nodules (SPN) where the probability of malignancy is lower...
Solitary pulmonary nodules: potential role of dynamic MR imaging in management initial experienceYoshiharu Ohno
Department of Radiology, Kobe University Graduate School of Medicine, 7 5 2 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
Radiology 224:503-11. 2002..To evaluate the utility of dynamic magnetic resonance (MR) imaging in the management of solitary pulmonary nodules (SPNs)...
GABA in the control of sympathetic preganglionic neuronsIda J Llewellyn-Smith
Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University, Bedford Park, South Australia, Australia
Clin Exp Pharmacol Physiol 29:507-13. 2002..are critical for controlling the activity of most central neurons, including sympathetic preganglionic neurons (SPN), the spinal cord neurons involved in controlling blood pressure and other autonomic functions. 2...
The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityEleanor Y M Sum
Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, Melbourne, Victoria 3050, Australia
J Biol Chem 277:7849-56. 2002..These findings reveal a novel complex between BRCA1, LMO4, and CtIP and indicate a role for LMO4 as a repressor of BRCA1 activity in breast tissue...
Stimulus-preceding negativity induced by fear: a manifestation of affective anticipationK B Böcker
Department of Psychopharmacology and Rudolf Magnus Institute of Neuroscience, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, Utrecht, The Netherlands
Int J Psychophysiol 43:77-90. 2001The Stimulus-Preceding Negativity (SPN), a slow cortical potential, has been studied in relation to anticipatory attention...
Diagnostic relevance of procalcitonin, IL-6, and sICAM-1 in the prediction of infected necrosis in acute pancreatitisY Mandi
Department of Medical Microbiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
Int J Pancreatol 28:41-9. 2000..The aim of the study was to analyze the clinical value of procalcitonin (PCT) for the prediction of infected necrosis, in comparison with interleukin-6 (IL-6) and sICAM 1...
Local collateral projections from the medial superior olive to the superior paraolivary nucleus in the gerbilN Kuwabara
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Health Sciences Center, Louisville, KY 40292, USA
Brain Res 846:59-71. 1999..the MSO as the latter passed through a dorsally neighboring periolivary nucleus, the superior paraolivary nucleus (SPN), toward the ipsilateral inferior colliculus (IC), their traditionally accepted target...
Research Grants
- Computerized Decision Support for Managing Lung NodulesMichael Gould; Fiscal Year: 2006..To achieve this overall goal, we have three specific aims: (1) to develop ALCHEMIST-SPN, an interactive decision support system for management of patients with solitary pulmonary nodules, by linking a ..
- Ventilator-induced diaphragm dysfunctionSanford Levine; Fiscal Year: 2009..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours before ..
- Ventilator-induced diaphragm dysfunctionSANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years;(b) same gender;(c) receives neuromuscular blocking agents <3 hours before ..
- Ventilator-induced diaphragm dysfunctionSanford Levine; Fiscal Year: 2007..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age ¿5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours ..
- Ventilator-induced diaphragm dysfunctionSanford Levine; Fiscal Year: 2009..We define a matched control as a patient with a solitary pulmonary nodule (SPN) that is (a) the same age 5 years; (b) same gender; (c) receives neuromuscular blocking agents <3 hours before ..
- Evaluation of Computerized Decision Support for Managing Lung NodulesMichael K Gould; Fiscal Year: 2010..Subsequently, we developed ALCHEMIST-SPN, a web-based decision support system for managing patients with solitary pulmonary nodules (SPN), by linking a ..
- Evaluation of Computerized Decision Support for Managing Lung NodulesMichael Gould; Fiscal Year: 2009..Subsequently, we developed ALCHEMIST-SPN, a web-based decision support system for managing patients with solitary pulmonary nodules (SPN), by linking a ..
- EARLY REPEAT CT FOR EVALUATION OF SOLITARY LUNG NODULESDavid Yankelevitz; Fiscal Year: 2004The solitary pulmonary nodule (SPN) is a common and challenging problem, with approximately 150,000 new SPNs being detected each year. The most common etiology of SPN remains lung cancer...
- DIAGNOSIS OF THE SOLITARY PULMONARY NODULE IMAGED ON CTMIKE MCNITT GRAY; Fiscal Year: 2003..The applicants proposed to develop a methodology to provide a more comprehensive examination of the SPN by coupling CT acquisition techniques (including investigating the use of contrast enhanced spiral scans) with ..
- CYTOLYSIN-MEDIATED TRANSLOCATION IN S. PYOGENES VIRULENCMichael G Caparon; Fiscal Year: 2010..pyogenes NAD-glycohydrolase (SPN) across the host cell membrane and into its cytosol...
- Bacteria-Mucin Interactions at the Ocular SurfaceIlene K Gipson; Fiscal Year: 2010..g., outbreaks of bacterial conjunctivitis from non-encapsulated Streptococcus pneumoniae (SPN), occur without evidence of ocular surface damage...
- STREPTOCOCCUS PNEUMONIAE ADHERENCE AND OTITIS MEDIA PATHThomas Demaria; Fiscal Year: 2004..Streptococcus pneumoniae (Spn), is one of the foremost human pathogens and is the primary nasopharynx, the initial event in the induction of OM ..
- Deaf1 isoforms control changes in PTA expression in the NOD PLN during T1D pathogCHARLES GARRISON FATHMAN; Fiscal Year: 2010..Our laboratory recently identified Deaf1 as a transcriptional regulator of PTA gene expression in peripheral lymph nodes...
- Complement in S.pneumoniae otitis MediaHua Hua Tong; Fiscal Year: 2009..Streptococcus pneumoniae (Spn) is one of the primary pathogens of OM...
- Complement in S.pneumoniae otitis MediaHua Hua Tong; Fiscal Year: 2010..Streptococcus pneumoniae (Spn) is one of the primary pathogens of OM...
- ATECAR: Asian Training, Education on Cancer & ResearchGrace Ma; Fiscal Year: 2007..The proposal goals and objectives are based on 5-years of ATECAR-SPN experience with Asian communities in this region and are supported by an elaborate system of experienced community-..
- Cytolysin-mediated translocation in S.pyogenes virulenceMichael Caparon; Fiscal Year: 2009..pyogenes NAD-glycohydrolase (SPN) into the host cell cytosol...
- NUDR--A Potential Tumor Suppressor of Childhood CancersJodi Huggenvik; Fiscal Year: 2005b>NUDR is a mammalian transcription factor with homology to Drosophila DEAF-1, a developmental cofactor of Hox and homeodomain proteins...
- Cytolysin-mediated translocation in S. pyogenes virulenceMichael Caparon; Fiscal Year: 2007..pyogenes NAD-glycohydrolase (SPN) into the host cell cytosol...
- RNA recognition by maternal gene silencers in nematodesSEAN PATRICK RYDER; Fiscal Year: 2010..we focus on the RNA-binding proteins that pattern Notch/glp-1 expression in the embryo (MEX-3, MEX-5, POS-1, SPN-4, and GLD-1)...
- Patient Navigation for CRC Screening with Low-Income MinoritiesWilliam H Redd; Fiscal Year: 2010..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
- Patient Navigation for CRC Screening with Low-Income MinoritiesWilliam Redd; Fiscal Year: 2007..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
- Patient Navigation for CRC Screening with Low-Income MinoritiesWilliam H Redd; Fiscal Year: 2010..Our preliminary data show that, even after implementation of standard patient navigation (SPN) (i.e...
- Biochemical & Genetic Analysis of Yeast SPNTimothy Formosa; Fiscal Year: 2005..Experiments in this proposal explore the nature of the changes induced in nucleosomes by Sptl6-Pob3-Nhp6 (SPN), with the goal of understanding how SPN changes the structure of this fundamental unit of genomic packaging...
- Acquision of Appllied Biosystems 3730 DNA Analyzer for the DNA Sciences CoreYongde Bao; Fiscal Year: 2007..following three important fronts: 1) DNA sequencing, 2) Genotyping including microsatilite and SNP analyses with Applied Biosystems SpaPshot , and 3) higher throughput SPN screening with Applied Biosystems oligo48-plex SNPlex analysis.
