gus

Summary

Gene Symbol: gus
Description: gustavus
Alias: A11, CG2944, CG2946, Dmel\CG2944, GUS, GUSTAVUS, Gus, dmSSB4, i25, CG2944-PA, CG2944-PB, CG2944-PC, CG2944-PD, CG2944-PE, CG2944-PF, gus-PA, gus-PB, gus-PC, gus-PD, gus-PE, gus-PF
Species: fruit fly

Top Publications

  1. ncbi VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS
    Sylvia Styhler
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada H3A 1B1
    Dev Cell 3:865-76. 2002
  2. ncbi Structural and functional insights into the B30.2/SPRY domain
    Jae Sung Woo
    Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Kyungbuk, Korea
    EMBO J 25:1353-63. 2006
  3. ncbi Structural basis for protein recognition by B30.2/SPRY domains
    Jae Sung Woo
    Center for Biomolecular Recognition, Department of Life Sciences, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang, Kyungbuk, 790 784, Korea
    Mol Cell 24:967-76. 2006
  4. ncbi Valois, a component of the nuage and pole plasm, is involved in assembly of these structures, and binds to Tudor and the methyltransferase Capsuléen
    Joël Anne
    Department of Developmental Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    Development 132:2167-77. 2005
  5. ncbi Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors
    Jan Michael Kugler
    Department of Biology, McGill University, Montreal, Quebec H3A 1B1, Canada
    Mol Cell Biol 30:1769-82. 2010
  6. ncbi Reduced cul-5 activity causes aberrant follicular morphogenesis and germ cell loss in Drosophila oogenesis
    Jan Michael Kugler
    Developmental Biology Research Initiative, Department of Biology, McGill University, Montreal, Quebec, Canada
    PLoS ONE 5:e9048. 2010
  7. ncbi Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2
    Alistair B Coulthard
    Department of Biology, York University, Toronto, Ontario M3J 1P3, Canada
    Genetics 185:479-95. 2010

Scientific Experts

  • Joël Anne
  • Jae Sung Woo
  • Jan Michael Kugler
  • Paul Lasko
  • Byung Ha Oh
  • Alistair B Coulthard
  • Jae-Sung Woo
  • Byung-Ha Oh
  • Sylvia Styhler
  • Fabrizio Rossi
  • Arthur J Hilliker
  • Christina Alm
  • Iulia Cealiac
  • Don A Sinclair
  • Barry M Honda
  • Patrizio Dimitri
  • Christopher Lem
  • Kyung-Jin Kim
  • Chang-Ki Min
  • Hye Young Suh
  • Sam Yong Park
  • Joon Hyuk Imm
  • Hye-Young Suh
  • Sun Shin Cha
  • Joon-Hyuk Imm
  • Kyung Jin Kim
  • Sam-Yong Park
  • Sun-Shin Cha
  • Chang Ki Min
  • Akira Nakamura

Detail Information

Publications7

  1. ncbi VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS
    Sylvia Styhler
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada H3A 1B1
    Dev Cell 3:865-76. 2002
    ..We identified a gene, gustavus (gus), that encodes a protein that interacts with VAS...
  2. ncbi Structural and functional insights into the B30.2/SPRY domain
    Jae Sung Woo
    Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Kyungbuk, Korea
    EMBO J 25:1353-63. 2006
    ..Here, we report the crystal structure of an SPRY-SOCS box family protein GUSTAVUS in complex with Elongins B and C, revealing a highly distorted two-layered beta-sandwich core structure of its ..
  3. ncbi Structural basis for protein recognition by B30.2/SPRY domains
    Jae Sung Woo
    Center for Biomolecular Recognition, Department of Life Sciences, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang, Kyungbuk, 790 784, Korea
    Mol Cell 24:967-76. 2006
    ..2/SPRY domain of a SPRY domain-containing SOCS box (SSB) protein, GUSTAVUS, complexed with a 20 amino acid peptide derived from the RNA helicase VASA, revealing how these domains recognize ..
  4. ncbi Valois, a component of the nuage and pole plasm, is involved in assembly of these structures, and binds to Tudor and the methyltransferase Capsuléen
    Joël Anne
    Department of Developmental Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    Development 132:2167-77. 2005
    ..As the PMRT5/MEP50 complex is involved in ribonucleoprotein complex assembly, we hypothesize that the Vls complex may play a similar function in assembling the nuage in nurse cells and the polar granules in the oocyte...
  5. ncbi Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors
    Jan Michael Kugler
    Department of Biology, McGill University, Montreal, Quebec H3A 1B1, Canada
    Mol Cell Biol 30:1769-82. 2010
    ..Here, we found that Gustavus (Gus) and Fsn, two ubiquitin Cullin-RING E3 ligase specificity receptors, bind to the same motif on Vasa through ..
  6. ncbi Reduced cul-5 activity causes aberrant follicular morphogenesis and germ cell loss in Drosophila oogenesis
    Jan Michael Kugler
    Developmental Biology Research Initiative, Department of Biology, McGill University, Montreal, Quebec, Canada
    PLoS ONE 5:e9048. 2010
    ..All of these cul-5 phenotypes are strongly enhanced by reduced activity of gustavus (gus), which encodes a substrate receptor of Cul-5-based ubiquitin E3 ligases...
  7. ncbi Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2
    Alistair B Coulthard
    Department of Biology, York University, Toronto, Ontario M3J 1P3, Canada
    Genetics 185:479-95. 2010
    ....