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Genomes and GenesSpecies | betaTub56DSummaryGene Symbol: betaTub56D Description: beta-Tubulin at 56D Alias: B1t, BETA 56D, CG9277, DTB2, Dmbeta1, Dmel\CG9277, Tub, Tubulin, beta-Tub, beta-Tub56D, beta-tub, beta-tubulin56D, beta1, beta1-Tubulin, beta1-tub, beta1Tub, beta1t, beta1tub, beta56D, betaTub1, beta[[1]] tubulin, beta[[1]]-tubulin, CG9277-PA, CG9277-PB, CG9277-PC, CG9277-PD, beta tubulin, beta-1 tubulin, beta-1-tubulin, beta-tubulin, beta-tubulin 56D, beta-tubulin-56D, beta1 tubulin, beta1-tubulin, betaTub56D-PA, betaTub56D-PB, betaTub56D-PC, betaTub56D-PD, betatubulin, tubulin Species: fruit fly Top Publications
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Publications
Axoneme specialization embedded in a "generalist" beta-tubulinEllen M Popodi
Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
Cell Motil Cytoskeleton 65:216-37. 2008The relationship between the primary structure of the beta-tubulin C-terminal tail (CTT) and axoneme structure and function is explored using the spermatogenesis-specific beta2-tubulin of Drosophila...- Transcription factor and polymerase recruitment, modification, and movement on dhsp70 in vivo in the minutes following heat shockAmber K Boehm
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Mol Cell Biol 23:7628-37. 2003..These studies of factor choreography set important limits in modeling transcription regulatory mechanisms... - Functional coordination of three mitotic motors in Drosophila embryosD J Sharp
Section of Molecular and Cellular Biology, University of California Davis, Davis, California 95616, USA
Mol Biol Cell 11:241-53. 2000..During anaphase, however, Ncd appears to have no effect on spindle pole movements, suggesting that its activity is down-regulated at this time, allowing dynein and KLP61F to drive spindle elongation during anaphase B... - Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in DrosophilaJ T Robinson
University of Minnesota, Department of Genetics, Cell Biology and Development, St Paul, Minnesota 55108 1095, USA
J Cell Biol 146:597-608. 1999..The disruption of these centrosome attachments in mutant embryos reveals a critical role for dynein function and centrosome positioning in the spatial organization of the syncytial cytoplasm of the developing embryo... - The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindlesD J Sharp
Section of Molecular and Cellular Biology, University of California Davis, Davis, California 95616, USA
J Cell Biol 144:125-38. 1999..Thus we propose that bipolar kinesin motors and MTs interact by a "sliding filament mechanism" during the formation and function of the mitotic spindle... - pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesisR R Adams
Cancer Research Campaign CRC Laboratories, Cell Cycle Genetics Research Group, Department of Anatomy and Physiology, Medical Sciences Institute, University of Dundee, Dundee DD1 4HN, UK
Genes Dev 12:1483-94. 1998..We suggest that PAV-KLP is required both to establish the structure of the telophase spindle to provide a framework for the assembly of the contractile ring, and to mobilize mitotic regulator proteins... - The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and functionNick Trotta
Department of Biological Sciences, Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37235, USA
Curr Biol 14:1135-47. 2004..Previous work in cell culture has proposed a role for Spastin in regulating microtubules... - During Drosophila embryogenesis the beta 1 tubulin gene is specifically expressed in the nervous system and the apodemesD Buttgereit
Gentechnologische Arbeitsgruppe am MPI für Biochemie, Martinsried Munchen, F R G
Mech Dev 33:107-18. 1991We determined the in vivo distribution of the beta 1 tubulin from D. melanogaster using isotype specific antibodies. Maternally expressed beta 1 tubulin is incorporated into mitotic spindles... - Epidermal muscle attachment site-specific target gene expression and interference with myotube guidance in response to ectopic stripe expression in the developing Drosophila epidermisG Vorbrüggen
Max Planck Institut fur biophysikalische Chemie, Abteilung Molekulare Entwicklungsbiologie, Am Fassberg, D 37077 Gottingen, Germany
Proc Natl Acad Sci U S A 94:8606-11. 1997..sr-expressing ectodermal cells generate long-range signals that interfere with the spatial orientation of the elongating myotubes... - The Drosophila neuregulin homolog Vein mediates inductive interactions between myotubes and their epidermal attachment cellsT Yarnitzky
Department of Molecular Genetics, The Weizmann Institute of Science, 76100 Rehovot, Israel
Genes Dev 11:2691-700. 1997..differentiation of tendon cells, measured by the level of expression of specific markers (Delilah and beta1 tubulin) is blocked... - Epidermal egr-like zinc finger protein of Drosophila participates in myotube guidanceG Frommer
Abteilung Molekulare Entwicklungsbiologie, Max Planck Institut fur biophysikalische Chemie, Gottingen, Germany
EMBO J 15:1642-9. 1996.... - Molecular characterization of Drosophila NELFChwen Huey Wu
Department of Biochemistry and Molecular Biology, Center for Gene Regulation, The Pennsylvania State University University Park, PA 16802, USA
Nucleic Acids Res 33:1269-79. 2005..Chromatin immunoprecipitation analyses detect NELF at the promoters of the hsp70 and beta1-tubulin genes where promoter proximal pausing has been previously detected... - Interaction of cytoskeleton genes with NSF2-induced neuromuscular junction overgrowthJean Baptiste Peyre
Department of Biology, Tokyo Metropolitan University, Tokyo, Japan
Genesis 44:595-600. 2006.... - rst and its paralogue kirre act redundantly during embryonic muscle development in DrosophilaM Strünkelnberg
Institut fur Biologie III, Schänzlestr 1, Albert Ludwigs Universitat, D 79104 Freiburg im Breisgau, Germany
Development 128:4229-39. 2001..This defect can be rescued by one copy of either gene. Moreover, Rst, like Kirre is a myoblast attractant... - The sex determination master switch, Sex-lethal, responds to Hedgehog signaling in the Drosophila germlineC Vied
Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1918 University Boulevard, Birmingham, Alabama 35294, USA
Development 128:2649-60. 2001..This is the first demonstration that downstream components of the Hedgehog signaling pathway regulate a target other than Cubitus interruptus... - Axoneme-specific beta-tubulin specialization: a conserved C-terminal motif specifies the central pairM G Nielsen
Indiana Molecular Biology Institute and Department of Biology, Indiana University, Bloomington, IN 47405, USA
Curr Biol 11:529-33. 2001..Consistent with this, alpha- and beta-tubulins utilized in motile axonemes fall among the most conserved tubulin sequences [1, 2], and the beta-tubulins contain a sequence motif at the same position in the carboxyl terminus [3].. - The oxen gene of Drosophila encodes a homolog of subunit 9 of yeast ubiquinol-cytochrome c oxidoreductase complex: evidence for modulation of gene expression in response to mitochondrial activityM V Frolov
University of Missouri, Columbia, Missouri 65211, USA
Genetics 156:1727-36. 2000..The oxen mutation provides a model for the genetic analysis in multicellular organisms of the effect of mitochondrial activity on nuclear gene expression... - The fusome organizes the microtubule network during oocyte differentiation in DrosophilaN C Grieder
Howard Hughes Medical Institute, Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
Development 127:4253-64. 2000..We have investigated how the microtubule network polarizes using a GFP-tubulin construct that allows germ-cell microtubules to be visualized with greater sensitivity than in previous studies... - Cooperativity between the beta-tubulin carboxy tail and the body of the molecule is required for microtubule functionEllen M Popodi
Department of Biology and Indiana Molecular Biology Institute, Indiana University, Bloomington, Indiana 47405, USA
Cell Motil Cytoskeleton 65:955-63. 2008Using Drosophila spermatogenesis as a model, we show that function of the beta-tubulin C-terminal tail (CTT) is not independent of the body of the molecule. For optimal microtubule function, the beta-tubulin CTT and body must match... - Integrins modulate the Egfr signaling pathway to regulate tendon cell differentiation in the Drosophila embryoM D Martin-Bermudo
Department of Anatomy, Cambridge University, Downing Street, Cambridge CB2 3DY, UK
Development 127:2607-15. 2000..In the absence of PS integrin function, the expression of tendon cell-specific genes such as stripe and beta1 tubulin is not maintained. In addition, embryos lacking the PS integrins also exhibit reduced levels of activated MAPK... - A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytesEdith Szafer-Glusman
Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305 5329, USA
Curr Biol 18:1426-31. 2008..Our findings implicate very-long-chain fatty acids or their derivative complex lipids in allowing supple membrane deformation and the stable connection of cortical contractile components to the plasma membrane during cell division... - Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell divisionS Bulgheresi
Research Institute of Molecular Pathology I M P, Dr Bohr Gasse 7, A 1030 Vienna, Austria
J Cell Sci 114:3655-62. 2001.... - Spindle assembly and cytokinesis in the absence of chromosomes during Drosophila male meiosisElisabetta Bucciarelli
Istituto Pasteur Fondazione Cenci Bolognetti, 00185 Rome, Italy
J Cell Biol 160:993-9. 2003..This suggests that the association of Aurora B with chromosomes is not a prerequisite for its accumulation at the central spindle, or for its function during cytokinesis... - Misregulation of sex-lethal and disruption of male-specific lethal complex localization in Drosophila species hybridsManika Pal Bhadra
Division of Biological Sciences, University of Missouri, Columbia 65211 7400, USA
Genetics 174:1151-9. 2006..Lethal hybrid rescue (Lhr), which allows hybrid males from this cross to survive, corrects the SXL and MSL defects. The reciprocal cross of D. simulans mothers by D. melanogaster males exhibits underexpression of Sxl in embryos... - The product of the split ends gene is required for the maintenance of positional information during Drosophila developmentKimberly Mace
Surgical Research Lab, University of California, San Francisco, Box 1302, San Francisco, CA 94143 1302, USA
BMC Dev Biol 4:15. 2004..Although spen mutants affect only a small subset of morphological structures in embryos, it has been difficult to find a common theme in spen mutant structural alterations, or in the interactions of spen with known signaling pathways... - Drosophila citron kinase is required for the final steps of cytokinesisValeria Naim
Istituto di Biologia e Patologia Molecolari del Consiglio Nazionale delle Ricerche, Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, 00185 Rome, Italy
Mol Biol Cell 15:5053-63. 2004.... - A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formationJulia E Dallman
Howard Hughes Medical Institute, State University of New York, Stony Brook, Stony Brook, New York 11794, USA
J Neurosci 24:7186-93. 2004.... - Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/MintJames Ashley
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605 2324, USA
J Neurosci 25:5943-55. 2005..These results provide a novel mechanism by which cell adhesion molecules are regulated and provide fresh insights into the normal operation of APP during synapse development... - Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammalsQiaofang Chen
Department of Pediatrics and Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA
J Exp Biol 207:3125-9. 2004..The mechanism of this protection is probably related to a decrease in protein denaturation through protein-trehalose interactions... - The abnormal spindle protein is required for germ cell mitosis and oocyte differentiation during Drosophila oogenesisMaria Giovanna Riparbelli
Department of Evolutionary Biology, University of Siena, I 53100, Italy
Exp Cell Res 298:96-106. 2004..spindles of the mutant cystocytes are composed by wavy microtubules and have abnormal poles that often lack gamma-tubulin. The fusome structure is also compromised... - Developmental expression of Rab11, a small GTP-binding protein in Drosophila epitheliaSatish Sasikumar
Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi 221 005, India
Genesis 47:32-9. 2009..genesis 47:32-39, 2009. (c) 2008 Wiley-Liss, Inc... - Drosophila starvin encodes a tissue-specific BAG-domain protein required for larval food uptakeMichelle Coulson
ARC Special Research Centre for the Molecular Genetics of Development, School of Molecular and Biomedical Sciences, University of Adelaide, Adelaide, SA 5005, Australia
Genetics 171:1799-812. 2005..Our study provides the first report of an essential, developmentally regulated BAG-family gene... - Asymmetric sequence divergence of duplicate genesGavin C Conant
Department of Biology, The University of New Mexico, Albuquerque, New Mexico 87131, USA
Genome Res 13:2052-8. 2003..The method is also more sensitive in detecting positive selection (Ka/Ks > 1) than models relying only on pairwise gene comparisons... - Assembly of yolk spindles in the early Drosophila embryoMaria Giovanna Riparbelli
Department of Evolutionary Biology, University of Siena, Via Aldo Moro 4, I 53100 Siena, Italy
Mech Dev 120:441-54. 2003..The presence of normal and abnormal centrosomes in the same cytoplasm provides an useful model for investigating the common regulators of the nucleus and centrosome cycle which ensure precise spindle pole duplication... - Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteinsGohta Goshima
The Howard Hughes Medical Institute and the Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94107, USA
J Cell Biol 171:229-40. 2005..From these results and simulations, we propose a model on how two minus end-directed motors cooperate to ensure spindle pole coalescence during mitosis... - The balance between two isoforms of the Drosophila RNA-binding protein how controls tendon cell differentiationH Nabel-Rosen
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
Mol Cell 4:573-84. 1999..This inhibition is likely to be counteracted by the short How(S) protein, present in both nucleus and cytoplasm, which is upregulated in the muscle-bound tendon cell following EGF receptor activation... - Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesodermJ Casal
Max Planck Institut fur Entwicklungsbiologie, Tubingen, Germany
Proc Natl Acad Sci U S A 93:10327-32. 1996..These novel genes show a variety of expression patterns and also differ in their dependence on twist and snail functions. This indicates that the regulation of early gene activity in the mesoderm is more complex than previously thought... - The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindleR D Saunders
Cancer Research Campaign, Cell Cycle Genetics Group, Department of Anatomy and Physiology, University of Dundee, Dundee DD1 4HN, Scotland
J Cell Biol 137:881-90. 1997..These findings are discussed in relation to the known spindle abnormalities in asp mutants... - Microtubule architecture specified by a beta-tubulin isoformE C Raff
Department of Biology and Indiana Molecular Biology Institute, Indiana University, Bloomington, IN 47405, USA
Science 275:70-3. 1997In Drosophila melanogaster, a testis-specific beta-tubulin (beta2) is required for spermatogenesis. A sequence motif was identified in carboxyl termini of axonemal beta-tubulins in diverse taxa... - Regulation of Drosophila alpha- and beta-tubulin genes during developmentJ E Natzle
Dev Biol 104:187-98. 1984Both the alpha and the beta subunit of tubulin in Drosophila melanogaster are encoded by small multigene families... - Genetics of microtubule systemsE C Raff
J Cell Biol 99:1-10. 1984In most eucaryotes the tubulin genes comprise small multigene families with approximately equal numbers of genes for alpha- and beta-tubulin, the structural proteins of microtubules... - Genetic analysis of the Drosophila beta3-tubulin gene demonstrates that the microtubule cytoskeleton in the cells of the visceral mesoderm is required for morphogenesis of the midgut endodermR W Dettman
Department of Biology and Institute for Molecular and Cellular Biology, Indiana University, Bloomington, Indiana, 47405, USA
Dev Biol 177:117-35. 1996We have investigated the cellular basis for lethality of mutant alleles of the Drosophila melanogaster beta3-tubulin gene, betaTub60D... - Redundant enhancer elements guide beta 1 tubulin gene expression in apodemes during Drosophila embryogenesisD Buttgereit
Philipps Universitat Marburg, Fachbereich Biologie Molekulargenetik, Germany
J Cell Sci 105:721-7. 1993During Drosophila embryogenesis, the beta 1 tubulin gene (beta Tub56D) is expressed in the CNS and PNS as well as in the apodemes... - The beta-tubulin genes of Drosophila auraria are arranged in a clusterZ G Scouras
Department of Genetics, School of Biology, Faculty of Science, Aristotelian University of Thessaloniki, Greece
Curr Genet 25:84-7. 1994When the beta 1-, beta 2- and beta 3-tubulin-specific DNAs from Drosophila melanogaster were used as probes to recognize tubulin-specific sequences in the chromosomes of Drosophila auraria, they were found to hybridize to the same .. - Polytene chromosomes of monogenic and amphogenic Chrysomya species (Calliphoridae, Diptera): analysis of banding patterns and in situ hybridization with Drosophila sex determining gene sequencesS Puchalla
Zoologisches Institut, Universitat Kiel, Germany
Chromosoma 103:16-30. 1994..rufifacies. An hypothesis for the evolution of the maternal effect sex determination of C. rufifacies is proposed... - The SR protein B52/SRp55 is essential for Drosophila developmentH Z Ring
Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York 14853
Mol Cell Biol 14:7499-506. 1994..Therefore, B52 is not required for all splicing in vivo. This is the first in vivo deficiency analysis of a member of the SR protein family... - Structural analysis of mutations in the Drosophila beta 2-tubulin isoform reveals regions in the beta-tubulin molecular required for general and for tissue-specific microtubule functionsJ D Fackenthal
Department of Biology, Indiana University, Bloomington 47405
Genetics 139:267-86. 1995..the lesions in a number of mutant alleles of beta Tub85D, the gene that encodes the testis-specific beta 2-tubulin isoform in Drosophila melanogaster... - A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycleD F Eberl
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
Genetics 146:951-63. 1997.... - Direct cloning of DNA that interacts in vivo with a specific protein: application to RNA polymerase II and sites of pausing in DrosophilaA Law
Section of Biochemsitry, Molecular and Cellular Biology, Biotechnology Building, Cornell University, Ithaca, NY 14853, USA
Nucleic Acids Res 26:919-24. 1998..At least some of these map to the 5'-ends of genes. These results suggest that transcriptional pausing of Pol II is a general phenomenon in vivo... - Testis-specific beta 2 tubulins are identical in Drosophila melanogaster and D. hydei but differ from the ubiquitous beta 1 tubulinF Michiels
Genzentrum am Max Planck Institut für Biochemie, Martinsried, Federal Republic of Germany
Chromosoma 95:387-95. 1987..This is discussed with reference to the possible functional domains of these proteins. The beta 1 tubulin gene of Drosophila is constitutively expressed, whereas the beta 2 tubulin is expressed specifically in the .. - The centrosome cycle in syncytial Drosophila embryos analyzed by energy filtering transmission electron microscopyA Debec
Laboratoire de Physiologie Cellulaire des Invertébrés, Universite Pierre et Marie Curie, Paris, France
Biol Cell 91:379-91. 1999..We conclude that in the early Drosophila embryo there is an unusual delay between the separation of the parent centrioles and their duplication. This leaves a surprisingly short time to assemble a daughter centriole... - During Drosophila spermatogenesis beta 1, beta 2 and beta 3 tubulin isotypes are cell-type specifically expressed but have the potential to coassemble into the axoneme of transgenic fliesB Kaltschmidt
Gentechnologische Arbeitsgruppe am Max Planck Institut für Biochemie, Martinsried Bundesrepublik Deutschland
Eur J Cell Biol 54:110-20. 1991..Thus, a switch of beta tubulin isotypes from beta 1 to beta 2 occurs during male germ cell differentiation... - A glial cell arises from an additional division within the mechanosensory lineage during development of the microchaete on the Drosophila notumG V Reddy
Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Rd, Mumbai 400 005 and the National Centre for Biological Sciences, TIFR, Bangalore 560 065, India
Development 126:4617-22. 1999..The proposed modification in lineage has important implications for previous studies on sibling cell fate choice and cell fate specification in sensory systems... - Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermisB M McCartney
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3280, USA
J Cell Biol 146:1303-18. 1999..We discuss the implications of our results for Wg signaling, and suggest a role for dAPC2 as a mediator of Wg effects on the cytoskeleton. We also speculate on more general roles that APCs may play in cytoskeletal dynamics... - Transcription elongation and eukaryotic gene regulationC A Spencer
Fred Hutchinson Cancer Research Center, Seattle, Washington 98104
Oncogene 5:777-85. 1990..We will also present evidence supporting the model that modifications to the RNA polymerase II transcription complex are pivotal to the control of transcriptional at the level of elongation... - Role of the male specific lethal (msl) genes in modifying the effects of sex chromosomal dosage in DrosophilaU Bhadra
Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211 7400, USA
Genetics 152:249-68. 1999.... - Development of larval body wall musclesM Bate
Department of Zoology, University of Cambridge, United Kingdom
Int Rev Neurobiol 43:25-44. 1999 - Sibling cell fate in the Drosophila adult external sense organ lineage is specified by prospero function, which is regulated by Numb and NotchG V Reddy
Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Rd, Mumbai 400005, India
Development 126:2083-92. 1999..Pros misexpression is sufficient for the transformation of PIIa to PIIb fate. The expression of Pros in the normal PIIb cell appears to be regulated by Notch signaling... - Kakapo, a novel cytoskeletal-associated protein is essential for the restricted localization of the neuregulin-like factor, vein, at the muscle-tendon junction siteD Strumpf
Department of Molecular Genetics, The Weizmann Institute of Science, 76100 Rehovot, Israel
J Cell Biol 143:1259-70. 1998..This may lead to aberrant differentiation of tendon cells and consequently to the kakapo mutant deranged somatic muscle phenotype... - A variant beta-tubulin isoform of Drosophila melanogaster (beta 3) is expressed primarily in tissues of mesodermal origin in embryos and pupae, and is utilized in populations of transient microtubulesM Kimble
Department of Biology, Indiana University, Bloomington 47405
Dev Biol 131:415-29. 1989The beta 3-tubulin gene of Drosophila melanogaster codes for a variant tubulin isoform which is expressed at two distinct times during development: (1) during midembryogenesis from 8-16 hr postfertilization, and (2) during the 4 days of .. - ncd and kinesin motor domains interact with both alpha- and beta-tubulinR A Walker
Department of Biology, Virginia Polytechnic Institute, Blacksburg 24061 0406, USA
Proc Natl Acad Sci U S A 92:5960-4. 1995..ncd, were found to saturate microtubule binding sites at a stoichiometry of approximately one motor domain per tubulin dimer... - The orientation of cell divisions determines the shape of Drosophila organsLuis Alberto Baena-Lopez
Centro de Biologia Molecular Severo Ochoa, Edificio Ciencias, Universidad Autonoma de Madrid, CX 504, 28049 Madrid, Spain
Curr Biol 15:1640-4. 2005..In addition, we find that a subset of planar cell polarity genes is required for the proper orientation of cell division during organ development... - Characterization and developmental expression of beta tubulin genes in Drosophila melanogasterS Bialojan
EMBO J 3:2543-8. 1984Genomic clones containing beta tubulin sequences were isolated from a lambda library of Drosophila melanogaster. In situ hybridization localized three genes to 56D and 60B on chromosome 2 as well as to 85D on chromosome 3... - Recruitment of ectodermal attachment cells via an EGFR-dependent mechanism during the organogenesis of Drosophila proprioceptorsAdi Inbal
Department of Genetics, Faculty of Medicine, Technion Israel Institute of Technology, Haifa 31096
Dev Cell 7:241-50. 2004..Molecular characterization of lch5 attachment cells demonstrated that they share significant properties with Drosophila tendon cells and with mammalian proprioceptive organs... - Induction of apoptosis in the germline and follicle layer of Drosophila egg chambersS Chao
Department of Biological Sciences, University of Iowa, Iowa City, IA 52242 1234, USA
Mech Dev 88:159-72. 1999..Germ cells degenerating as a normal consequence of oogenesis displayed a similar set of phenotypes, suggesting that a common apoptotic mechanism may underlie these different germline death phenomena... - Transcription of the beta 1 tubulin (beta Tub56D) gene in apodemes is strictly dependent on muscle insertion during embryogenesis in Drosophila melanogasterD Buttgereit
Fachbereich Biologie Molekulargenetik, Philipps Universitat, Marburg Germany
Eur J Cell Biol 71:183-91. 1996..Evidence from earlier experiments suggested that the expression of the beta 1 tubulin gene from D. melanogaster in the epidermal attachments may be dependent upon myotube insertion... - Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisionsFengwei Yu
MRC Centre for Developmental Neurobiology, 4th Fl, New Hunts House, Guy s Campus, King s College London, London SE1 1UL, UK
J Cell Biol 162:623-33. 2003..Importantly, our results have also revealed a novel aspect of apical complex function, that is, the two apical pathways act redundantly to suppress the formation of basal astral microtubules in neuroblasts... - Homeotic gene action in embryonic brain development of DrosophilaF Hirth
Institute of Zoology, University of Basel, Basel, Switzerland
Development 125:1579-89. 1998..Our findings demonstrate that the action of the homeotic genes labial and Deformed are required for neuronal differentiation in the developing brain of Drosophila... - The paternal effect gene ms(3)sneaky is required for sperm activation and the initiation of embryogenesis in Drosophila melanogasterK R Fitch
Department of Genetics, University of Washington, Seattle 98195, USA
Dev Biol 197:270-82. 1998..Immunolocalization of tubulin and Drosophila Centrosomin, a known centrosomal component, showed that snky-inseminated eggs failed to .. - Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulationJ Lis
Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York 14853, USA
Cold Spring Harb Symp Quant Biol 63:347-56. 1998 - Developmental and cell biological functions of the Drosophila DEAD-box protein abstraktU Irion
Institute of Genetics, University of Cologne, Wellcome CRC Institute, Cologne, Cambridge, D 50931, CB2 1QR, Germany, UK
Curr Biol 9:1373-81. 1999..The study of their function in multicellular organisms has been restricted to a few special cases, such as the Vasa protein in the fruit fly Drosophila... - The positioning and segregation of apical cues during epithelial polarity establishment in DrosophilaTony J C Harris
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
J Cell Biol 170:813-23. 2005..These results reveal key steps in the assembly of the apical domain in Drosophila...
Research Grants
- Role of the Archipelago gene in Drosophila tracheal morphogenesisKenneth H Moberg; Fiscal Year: 2010..Thus, we hypothesize that ago plays an important role in the homeostatic mechanisms that restrain tracheal branching. Our goal in Specific Aim 3 is to define this role and elucidate its molecular basis. ..
- Control of tissue growth and architecture by Drosophila Tsg101KENNETH MOBERG; Fiscal Year: 2009....
- Role of the Archipelago gene in Drosophila tracheal morphogenesisKENNETH MOBERG; Fiscal Year: 2009..Thus, we hypothesize that ago plays an important role in the homeostatic mechanisms that restrain tracheal branching. Our goal in Specific Aim 3 is to define this role and elucidate its molecular basis. ..
- Control of tissue growth and architecture by Drosophila Tsg101KENNETH MOBERG; Fiscal Year: 2007....
- Role of the Archipelago gene in Drosophila tracheal morphogenesisKENNETH MOBERG; Fiscal Year: 2007..Thus, we hypothesize that ago plays an important role in the homeostatic mechanisms that restrain tracheal branching. Our goal in Specific Aim 3 is to define this role and elucidate its molecular basis. ..
- Genetic Control of Tubulin Function in DevelopmentELIZABETH RAFF; Fiscal Year: 2005..The basic subunit of microtubules is the alpha, Beta-tubulin heterodimer...
- GENETIC CONTROL OF MICROTUBULE FUNCTION IN DEVELOPMENTELIZABETH RAFF; Fiscal Year: 2000..The basic unit in microtubule assembly is the alpha, beta tubulin heterodimer...
- Control of tissue growth and architecture by Drosophila Tsg101Kenneth H Moberg; Fiscal Year: 2010....