Guang Lan Zhang

Summary

Publications

  1. ncbi PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Nucleic Acids Res 33:W180-3. 2005
  2. ncbi Prediction of HLA-DQ3.2beta ligands: evidence of multiple registers in class II binding peptides
    Joo Chuan Tong
    Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore 8 Medical Drive, Singapore 117597, Singapore
    Bioinformatics 22:1232-8. 2006
  3. ncbi PREDNOD, a prediction server for peptide binding to the H-2g7 haplotype of the non-obese diabetic mouse
    Menaka Rajapakse
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore, Singapore, 119613
    Autoimmunity 39:645-50. 2006
  4. ncbi Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    BMC Bioinformatics 9:S19. 2008
  5. ncbi Prediction of supertype-specific HLA class I binding peptides using support vector machines
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613, Singapore
    J Immunol Methods 320:143-54. 2007
  6. ncbi MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Nucleic Acids Res 33:W172-9. 2005
  7. ncbi AllerTool: a web server for predicting allergenicity and allergic cross-reactivity in proteins
    Zong Hong Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Bioinformatics 23:504-6. 2007
  8. ncbi Neural models for predicting viral vaccine targets
    Guang Lan Zhang
    Institute for Infocomm Research, Singapore, 119613, Singapore
    J Bioinform Comput Biol 3:1207-25. 2005

Detail Information

Publications8

  1. ncbi PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Nucleic Acids Res 33:W180-3. 2005
    ..PRED(BALB/c) is available at http://antigen.i2r.a-star.edu.sg/predBalbc/...
  2. ncbi Prediction of HLA-DQ3.2beta ligands: evidence of multiple registers in class II binding peptides
    Joo Chuan Tong
    Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore 8 Medical Drive, Singapore 117597, Singapore
    Bioinformatics 22:1232-8. 2006
    ..2beta peptides and illustrate that several registers exist within a candidate binding peptide. Further analysis reveals that peptides with multiple registers occur predominantly for high-affinity binders...
  3. ncbi PREDNOD, a prediction server for peptide binding to the H-2g7 haplotype of the non-obese diabetic mouse
    Menaka Rajapakse
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore, Singapore, 119613
    Autoimmunity 39:645-50. 2006
    ..We have developed a prediction system, PREDNOD, for accurate identification of peptides that bind the MHC molecules constituting the H-2g7 haplotype. PREDNOD is accessible at http://antigen.i2r.a-star.edu.sg/Ag7...
  4. ncbi Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    BMC Bioinformatics 9:S19. 2008
    ..Given the large size of pathogen proteomes, including of variant strains, computational tools are necessary for automated screening and selection of immunological hotspots...
  5. ncbi Prediction of supertype-specific HLA class I binding peptides using support vector machines
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613, Singapore
    J Immunol Methods 320:143-54. 2007
    ..The SVM prediction models were integrated into a web-based computational system MULTIPRED1, accessible at antigen.i2r.a-star.edu.sg/multipred1/...
  6. ncbi MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides
    Guang Lan Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Nucleic Acids Res 33:W172-9. 2005
    ..MULTIPRED can be used for the mapping of promiscuous T-cell epitopes as well as the regions of high concentration of these targets--termed T-cell epitope hotspots. MULTIPRED is available at http://antigen.i2r.a-star.edu.sg/multipred/...
  7. ncbi AllerTool: a web server for predicting allergenicity and allergic cross-reactivity in proteins
    Zong Hong Zhang
    Institute for Infocomm Research, 21 Heng Mui Keng Terrace, Singapore 119613
    Bioinformatics 23:504-6. 2007
    ..90 with 86.00% sensitivity (SE) at specificity (SP) of 86.00%. Availability: AllerTool is freely available at http://research.i2r.a-star.edu.sg/AllerTool/...
  8. ncbi Neural models for predicting viral vaccine targets
    Guang Lan Zhang
    Institute for Infocomm Research, Singapore, 119613, Singapore
    J Bioinform Comput Biol 3:1207-25. 2005
    ..MULTIPRED not only predicts individual 9-mer binders but also predicts antigenic hot spots. Two HLA-A2 hot-spots in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) membrane protein were predicted by using MULTIPRED...