Research Topics
Species | Hitten P ZaveriSummaryAffiliation: Yale University Country: USA Publications
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Publications
Measuring the coherence of intracranial electroencephalogramsH P Zaveri
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
Clin Neurophysiol 110:1717-25. 1999..The performance characteristics of the coherence estimator and statistical testing of coherence estimates are described in this manuscript...
Localization-related epilepsy exhibits significant connectivity away from the seizure-onset areaHitten P Zaveri
Departments of Neurology, Yale University, New Haven, CT 06520, USA
Neuroreport 20:891-5. 2009..We show significant nonzero connectivity not only for the seizure-onset area but also several centimeters from it, for example, for the beta-frequency band (P<10(-5)), suggesting a nonlocal character to this disorder...
A decrease in EEG energy accompanies anti-epileptic drug taper during intracranial monitoringHitten P Zaveri
Department of Neurology, Yale University, 333 Cedar Street, New Haven, CT 06520, USA
Epilepsy Res 86:153-62. 2009..We measured change in signal energy of icEEGs in response to AED taper to quantify changes in excitation which accompany the increased propensity for seizures...
On the use of bipolar montages for time-series analysis of intracranial electroencephalogramsHitten P Zaveri
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
Clin Neurophysiol 117:2102-8. 2006....
Background intracranial EEG spectral changes with anti-epileptic drug taperHitten P Zaveri
Department of Neurology, Yale University, New Haven, CT 06520, USA
Clin Neurophysiol 121:311-7. 2010..Here, we expand the measures evaluated to icEEG power and frequency band power...
Seizure prediction: the Fourth International WorkshopHitten P Zaveri
Department of Neurology, Yale University, New Haven, CT 06520, USA
Epilepsy Behav 19:1-3. 2010..IWSP4 allowed the presentation and discussion of results, an exchange of ideas, an assessment of the status of seizure prediction, control, and related fields, and the fostering of collaborative projects...
Distinguishing subtypes of temporal lobe epilepsy with background hippocampal activityH P Zaveri
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, U S A
Epilepsia 42:725-30. 2001..This report describes a retrospective study to investigate the feasibility of doing so during intracranial monitoring...
The effect of a scalp reference signal on coherence measurements of intracranial electroencephalogramsH P Zaveri
Department of Neurology, Yale University School of Medicine, CT 06520, New Haven, USA
Clin Neurophysiol 111:1293-9. 2000..To determine the effect of a scalp reference signal, such as that recorded from the mastoid or ear, on the coherence of referential intracranial electroencephalograms (EEGs)...
Spatial distribution of intracranially recorded spikes in medial and lateral temporal epilepsiesIrina I Goncharova
Departments of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA
Epilepsia 50:2575-85. 2009..To test this hypothesis, we studied the spatial distribution of intracranially recorded interictal spikes in patients with medial temporal (MT) and lateral temporal (LT) neocortical seizure onset...
The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic studyYue Wang
Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA
Exp Neurol 220:293-302. 2009..In conclusion, the model of intrahippocampal MSO infusion replicates key features of human MTLE and may represent a useful tool for further studies of the cellular, molecular and electrophysiological mechanisms of this disorder...
Interictal spikes on intracranial recording: behavior, physiology, and implicationsSusan S Spencer
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Epilepsia 49:1881-92. 2008..We systematically analyzed the frequency, occurrence, and distribution of IISs recorded from multiple intracranial electrodes in 34 refractory epileptic patients with respect to seizures and antiepileptic drug (AED) changes...
Effects of working memory load on oscillatory power in human intracranial EEGJed A Meltzer
Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA
Cereb Cortex 18:1843-55. 2008....
A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategoriesNihal C de Lanerolle
Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8082, U S A
Epilepsia 44:677-87. 2003..We attempted to relate neuronal density, immunohistochemistry, electrophysiologic data, and surgical outcome...
Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in ratsTore Eid
Department of Laboratory Medicine, Yale University School of Medicine, 333 Cedar Street, P O Box 208035, New Haven, CT 06520 8035, USA
Brain 131:2061-70. 2008....
Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patientsIdil Cavus
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
Epilepsia 49:1358-66. 2008..Temporal lobe epilepsy (TLE) is associated with smaller hippocampal volume and with elevated extracellular (EC) glutamate levels. We investigated the relationship between the hippocampal volume and glutamate in refractory TLE patients...
Neocortical and thalamic spread of amygdala kindled seizuresHal Blumenfeld
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
Epilepsia 48:254-62. 2007..The mechanisms for worsening behavioral seizures, and the possible role of enhanced connectivity between the amygdala and other structures have not been thoroughly investigated...
Impaired consciousness in temporal lobe seizures: role of cortical slow activityDario J Englot
Department of Neurosurgery, University of California, San Francisco, CA 94122, USA
Brain 133:3764-77. 2010..Further investigations will be needed to fully determine the role of cortical-subcortical networks in ictal neocortical dysfunction and may reveal treatments to prevent this important negative consequence of temporal lobe epilepsy...
Intracranial EEG power and metabolism in human epilepsyJ W Pan
Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
Epilepsy Res 87:18-24. 2009..These data are also consistent with the hypothesis that high frequency activity is an abnormal manifestation of tissue injury...
Coherence of the electroencephalogram during the first sleep cycleR B Duckrow
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
Clin Neurophysiol 116:1088-95. 2005..We sought to characterize the spatial relationship of cortical activity at different frequencies during the first sleep cycle, focusing on sleep stages 3 and 4 (slow wave sleep)...
Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsyFredrik Lauritzen
Department of Laboratory Medicine, Yale University School of Medicine, P O Box 208035, New Haven, CT 06520, USA
Neurobiol Dis 45:165-76. 2012..These hypotheses can now be rigorously tested in several animal models that replicate key features of human TLE...
Temporal distributions of seizure occurrence from various epileptogenic regionsT S Durazzo
Department of Neurology, Yale University, New Haven, CT 06520, USA
Neurology 70:1265-71. 2008..For these ends, we determined and analyzed detailed temporal distributions of seizures arising from the frontal, parietal, occipital, neocortical temporal, and mesial temporal lobes...
Local spatial effect of 50 Hz cortical stimulation in humansRyder P Gwinn
Epilepsy Center, Seattle Neuroscience Institute, Seattle, Washington, USA
Epilepsia 49:1602-10. 2008..To help characterize this effect, we analyzed electrocorticography (ECoG) recorded adjacent to stimulated contacts during and after bipolar stimulation in patients undergoing functional cortical mapping with subdural electrodes...
Research Grants
- Third International Workshop on Seizure Prediction - Freiburg, Germany, 2007Hitten Zaveri; Fiscal Year: 2007..Investigators whose participation will be supported will be invited speakers and junior and senior investigators including women and racial and ethnic minorities. ..
