Research Topics
| Luis N MarencoSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
AlzPharm: integration of neurodegeneration data using RDFHugo Y K Lam
Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA
BMC Bioinformatics 8:S4. 2007....
The NIF DISCO Framework: facilitating automated integration of neuroscience content on the webLuis Marenco
Center for Medical Informatics, Yale University School of Medicine, PO Box 208009, New Haven, CT 06520 8009, USA
Neuroinformatics 8:101-12. 2010..Although DISCO is used by NIF to facilitate neuroscience data integration, its capabilities have general applicability to other areas of research...
The NIF LinkOut broker: a web resource to facilitate federated data integration using NCBI identifiersLuis Marenco
Department of Anesthesiology, Center for Medical Informatics, Yale University School of Medicine, New Haven, CT, 06520 8009, USA
Neuroinformatics 6:219-27. 2008..This approach can allow other resources (in addition to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses certain design issues that arose during its implementation...
Automated database mediation using ontological metadata mappingsLuis Marenco
Center for Medical Informatics, Yale University School of Medicine, PO Box 208009, New Haven, CT 06520 8009, USA
J Am Med Inform Assoc 16:723-37. 2009..To devise an automated approach for integrating federated database information using database ontologies constructed from their extended metadata...
QIS: A framework for biomedical database federationLuis Marenco
Center for Medical Informatics, Yale University, School of Medicine, New Haven, CT 06520 8009, USA
J Am Med Inform Assoc 11:523-34. 2004..Metadata version difference determination coupled with decomposition of stored queries is used as the basis for partial query recovery when the schema of data sources alters...
Achieving evolvable Web-database bioscience applications using the EAV/CR framework: recent advancesLuis Marenco
Center for Medical Informatics, Yale University School of Medicine, PO Box 208009, New Haven, CT 06520 8009, USA
J Am Med Inform Assoc 10:444-53. 2003....
Issues in the design of a pilot concept-based query interface for the neuroinformatics information frameworkLuis Marenco
Department of Anesthesiology, Center for Medical Informatics, Yale University School of Medicine, P O Box 208009, New Haven, CT, 06520 8009, USA
Neuroinformatics 6:229-39. 2008..The paper concludes by discussing certain lessons learned in the development of the current version of the interface...
Text mining neuroscience journal articles to populate neuroscience databasesChiquito J Crasto
Center for Medical Informatics, Yale University, New Haven, CT, USA
Neuroinformatics 1:215-37. 2003..Software that uses the NeuroText approach can facilitate the creation of curated, special-interest, bibliography databases...
Semantic SenseLab: Implementing the vision of the Semantic Web in neuroscienceMatthias Samwald
Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06520 8009, USA
Artif Intell Med 48:21-8. 2010..This paper describes the use of the Web Ontology Language (OWL) and other Semantic Web technologies for the representation and integration of molecular-level data provided by several of SenseLab suite of neuroscience databases...
Approaches to neuroscience data integrationKei Hoi Cheung
Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06511, USA
Brief Bioinform 10:345-53. 2009..The facets are also used to define the structure of the query results...
Olfactory Receptor Database: a metadata-driven automated population from sources of gene and protein sequencesChiquito Crasto
Center for Medical Informatics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 05611, USA
Nucleic Acids Res 30:354-60. 2002..Three population methods: batch, automatic and semi-automatic population are discussed. The data is imported into the database using extensible markup language (XML)...
Dynamic tables: an architecture for managing evolving, heterogeneous biomedical data in relational database management systemsJohn Corwin
Department of Computer Science, Yale University, P O Box 208285, New Haven, CT 06520 8285, USA
J Am Med Inform Assoc 14:86-93. 2007..The performance results show that their architecture is a promising technique for storing and processing many types of data that are not handled well by the other two semantic data models...
ResourceLog: an embeddable tool for dynamically monitoring the usage of web-based bioscience resourcesNian Liu
Center for Medical Informatics, Yale University School of Medicine, 300 George Street, Suite 501, New Haven, CT 06511, USA
J Am Med Inform Assoc 13:432-7. 2006..ResourceLog provides a robust and useful tool to aid system evaluation of a resource-driven Web application, with a focus on determining the effectiveness of data sharing in the field and with the general public...
Informatics approaches to functional MRI odor mapping of the rodent olfactory bulb: OdorMapBuilder and OdorMapDBNian Liu
Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06520, USA
Neuroinformatics 2:3-18. 2004..Both OdorMapBuilder and OdorMapDB should serve as useful tools and resources for the field and help facilitate experimental research in understanding the olfactory system and the mechanism for smell perception...
Database architectures for neuroscience applicationsPrakash Nadkarni
Yale Center for Medical Informatics, Yale University School of Medicine, New Haven, CT, USA
Methods Mol Biol 401:37-52. 2007..Recording validation constraints on individual items, as well as information on how they are to be presented, facilitates automatic or semi-automatic generation of robust user interfaces...
Interoperability across neuroscience databasesLuis Marenco
Yale Center for Medical Informatics, Yale University School of Medicine, New Haven, CT, USA
Methods Mol Biol 401:23-36. 2007..We also describe current data sharing and integration mechanisms in genera. We conclude with data integration in bioscience and present approaches on neuroscience data sharing...
SenseLab: new developments in disseminating neuroscience informationChiquito J Crasto
Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA
Brief Bioinform 8:150-62. 2007..We describe here: the new features for each database, the evolution of SenseLab's unifying database architecture and instances of SenseLab database interoperation with other neuroscience online resources...
Research Grants
- Mediated Integration of Neuroscience ResourcesLuis Marenco; Fiscal Year: 2007....
