Research Topics
Species | Rossitza LazovaSummaryAffiliation: Yale University Country: USA Publications
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Publications
Imaging mass spectrometry--a new and promising method to differentiate Spitz nevi from Spitzoid malignant melanomasRossitza Lazova
Department of Dermatology, Yale University School of Medicine and the Yale Cancer Center, New Haven, CT 06520, USA
Am J Dermatopathol 34:82-90. 2012..Differentiating Spitz nevus (SN) from Spitzoid malignant melanoma (SMM) is one the most difficult problems in dermatopathology. SPECIFIC AIM: To identify differences on proteomic level between SN and SMM...- Promontory sign--present in patch and plaque stage of angiosarcoma!Rossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
Am J Dermatopathol 31:132-6. 2009..The presence of promontory sign has not been emphasized in lesions other than Kaposi sarcoma, but seems to be a feature that is not uncommon in patch/plaque stage AS... - P75 nerve growth factor receptor staining is superior to S100 in identifying spindle cell and desmoplastic melanomaRossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520 8059, USA
J Am Acad Dermatol 63:852-8. 2010..Conventional melanocytic markers in SCM are usually negative... - Leukocyte-cancer cell fusion: initiator of the warburg effect in malignancy?Rossitza Lazova
Department of Dermatology, Yale Cancer Center, Yale University School of Medicine, New Haven, CT, 06520 8059, USA
Adv Exp Med Biol 714:151-72. 2011.... - The characteristic histopathologic features of nevi on and around the earRossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
J Cutan Pathol 32:40-4. 2005..The purpose of this study was to characterize the distinctive features of nevi with a junctional component located on and around the ear... - CD56 staining in Merkel cell carcinoma and natural killer-cell lymphoma: magic bullet, diagnostic pitfall, or both?Jennifer M McNiff
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
J Cutan Pathol 32:541-5. 2005..In MCC altered by crush artifact or obscured by lymphocytes, the histologic features coupled with CD56 positivity can lead to an erroneous impression of NK-cell lymphoma... - Why do melanomas get so dark?Rossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
Exp Dermatol 18:934-8. 2009..In any event, pigmentation in melanoma, long considered as a secondary aspect of the malignancy, may be a visible warning that the cells have gained competence for invasion and metastasis... - Fatal HHV6 infection in an immunocompromised patient presenting with skin involvementAnjela Galan
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
J Cutan Pathol 37:277-81. 2010..Although rare, HHV6 virus may be an important pathogen in immunocompromised patients, and may present initially in the skin. Awareness of this infection is critical to diagnosis in acute settings... - Cellular digital fibromas: distinctive CD34-positive lesions that may mimic dermatofibrosarcoma protuberansJennifer M McNiff
Departments of Dermatology and Pathology, Yale University School of Medicine, New Haven, CT, USA
J Cutan Pathol 32:413-8. 2005..Digital fibromas are common benign acral tumors typically reported as angiofibromas (AFs) or acquired digital fibrokeratomas (ADFs). Cellular variants are not well recognized... - Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcomeRossitza Lazova
Departments of Dermatology and Pathology, Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06520, USA
Clin Cancer Res 18:370-9. 2012..Accordingly, we investigated LC3B as an autophagosome marker by analyzing nearly 1,400 tumors from 20 types of cancer, focusing on correlations with clinical outcomes in melanoma and breast cancer... - Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanomaMary M McCarthy
Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Clin Cancer Res 12:3856-63. 2006..We assessed TRAIL-R1 and TRAIL-R2 expression patterns in a large cohort of melanomas and benign nevi... - Congenital melanocytic neviMaya Zayour
Yale Dermatopathology Laboratory, Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
Clin Lab Med 31:267-80. 2011..The risk for development of malignant melanoma in association with a congenital melanocytic nevus and variable causes for changing mole are discussed... - Autophagy in cutaneous malignant melanomaRossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
J Cutan Pathol 37:256-68. 2010..The results suggest that therapies inhibiting autophagy may be effective for the treatment of malignant melanoma by depriving cells of an important energy source... - Pseudoepitheliomatous hyperplasia: a reviewMaya Zayour
Dermatology and Pathology, Yale Dermatopathology Laboratory, Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Dermatopathol 33:112-22; quiz 123-6. 2011..Herein, we review different inflammatory, infectious, and neoplastic skin diseases, in which florid epidermal hyperplasia is a prominent histopathologic feature, and introduce a systematic approach in the interpretation of PEH... - The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasisRossitza Lazova
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06510, USA rossitza lazoraoyale edu
Am J Dermatopathol 31:177-81. 2009..Our data show a significant loss of Plexin C1 in metastatic melanoma compared with primary melanoma, suggesting the possibility that the Plexin C1 receptor is a tumor suppressor protein for melanoma... - P75 nerve growth factor receptor as a useful marker to distinguish spindle cell melanoma from other spindle cell neoplasms of sun-damaged skinAlicia C Sigal
Department of Dermatology, Yale University School of Medicine, 15 York Street, New Haven, CT 06520, USA
Am J Dermatopathol 34:145-50. 2012..This marker exhibits greater sensitivity than S100 in identifying SCM and may be a useful diagnostic and ancillary stain especially in the setting of an S100 negative spindle cell neoplasm... - A distinct entity in the spectrum of the CD30+ cutaneous lymphoproliferative diseases: oligolesional nodules with pseudoepitheliomatous hyperplasia followed by spontaneous resolutionMaya Zayour
Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
Am J Dermatopathol 31:37-43. 2009..Because most of these cases follow a relatively benign clinical course, we recommend a more conservative approach in the clinical management of these patients... - Urticarial vasculitis in an infantPhoebe E Koch
Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520 8059, USA
Cutis 81:49-52. 2008..His lesions appeared as erythematous wheals followed by the development of purpuric papules and resolving with ecchymoses and postinflammatory hyperpigmentation. Laboratory studies and skin biopsy results were consistent with UV... - Bazex syndrome (acrokeratosis paraneoplastica)Brian Poligone
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
Lancet 369:530. 2007 - Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosisSeverine M Chavel
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA
J Am Acad Dermatol 50:S125-8. 2004.... - Fatal childhood calciphylaxis in a 10-year-old and literature reviewJing Feng
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520-8059, USA
Pediatr Dermatol 23:266-72. 2006..Parathyroidectomy in combination with supportive medical management may be the best treatment option in stopping the progression of disease in the pediatric population... - Minocycline hyperpigmentation isolated to the subcutaneous fatZakia Rahman
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA
J Cutan Pathol 32:516-9. 2005..Special stain for iron was negative. This is the first case to our knowledge with pigment exclusively located in the subcutaneous fat and with the unusual finding of a negative stain for iron... - Iron in skin of mice with three etiologies of systemic iron overloadBrian D Adams
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA
J Invest Dermatol 125:1200-5. 2005..It appears that neither Hfe deletion nor elevated skin iron alone can account for cutaneous manifestations reportedly seen in humans with hereditary hemochromatosis... - Calcinosis cutis: a complication of intravenous administration of calcium glucanateJeremy Moss
Department of Dermatology, Yale University, New Haven, CT 06890, USA
J Cutan Pathol 33:60-2. 2006..While iatrogenic calcinosis cutis is generally a benign entity, it is important to recognize its unique clinical and histopathologic presentation to avoid complications from misdiagnosis... - Cutaneous natural killer/T-cell lymphomaMichael A Radonich
Department of Dermatology, Yale Dermatopathology Laboratory, Yale University School of Medicine, 15 York Street, New Haven, CT 06520-8059, USA
J Am Acad Dermatol 46:451-6. 2002..We report a case of aggressive NK-cell leukemia/lymphoma with numerous secondary cutaneous lesions and review the clinical and histopathologic spectrum of non-nasal CD56(+) lymphomas, with an emphasis on the dermatologic findings... - Subcutaneous fat necrosis of the newborn presenting as a large plaque with lobulated cystic areasErika Balfour
Yale University School of Medicine, New Haven, Connecticut 06520-8059, USA
Cutis 70:169-73. 2002..Most cases are related to some form of fetal distress, including obstetric trauma. Some cases are associated with hypercalcemia. We report a case of SFN with an unusual clinical presentation, complicated by hypercalcemia... - Cutaneous larva migrans with parts of the larva in the epidermisErika Balfour
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Cutis 69:368-70. 2002..We report a case with parts of the larva migrans in the epidermis on histologic examination... - Histopathologic misdiagnoses and their clinical consequencesIngrid H Olhoffer
Arch Dermatol 138:1381-3. 2002