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Genomes and Genes | Ivana KawikovaSummaryAffiliation: Yale University Country: USA Publications
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Publications
Decreased numbers of regulatory T cells suggest impaired immune tolerance in children with tourette syndrome: a preliminary studyIvana Kawikova
Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA
Biol Psychiatry 61:273-8. 2007..We also postulated that group A beta hemolytic streptococcal infections could promote autoimmune responses by releasing exotoxins (streptococcal pyrogenic exotoxins [SPE])...- Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette's syndromeJames F Leckman
Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
Biol Psychiatry 57:667-73. 2005..This study was carried out to investigate whether cytokines associated with the innate immune response or T cell activation were altered under baseline conditions and during periods of symptom exacerbation... - Children with Tourette's syndrome may suffer immunoglobulin A dysgammaglobulinemia: preliminary reportIvana Kawikova
Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Biol Psychiatry 67:679-83. 2010..We hypothesized that antineuronal antibodies may be elevated in patients (reflecting autoimmune processes), and levels of total immunoglobulins (Igs) may be decreased (reflecting immune deficiency)... - Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthmaIvana Kawikova
Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
Immunology 113:234-45. 2004.... - Early delayed-type hypersensitivity eosinophil infiltrates depend on T helper 2 cytokines and interferon-gamma via CXCR3 chemokinesMoe Akahira-Azuma
Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 0813, USA
Immunology 111:306-17. 2004..These results suggest that both a Th2-like (IL-5, IL-4 and STAT-6) and a Th1-like (IFN-gamma, IP-10, CXCR3) pathway contribute to eosinophil recruitment in early delayed-type hypersensitivity... - Streptococcal upper respiratory tract infections and exacerbations of tic and obsessive-compulsive symptoms: a prospective longitudinal studyJames F Leckman
Child Study Center and the Yale Center for Clinical Investigation, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520 7900, USA
J Am Acad Child Adolesc Psychiatry 50:108-118.e3. 2011..A group of children with Tourette syndrome and/or OC disorder without a PANDAS history served as the comparison (non-PANDAS) group... - Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: kappa light chains recruit T cells independent of complementVipin Paliwal
Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
J Immunol 169:4113-23. 2002..Thus, B-1 cell-mediated CS initiation required for T cell recruitment is due to activation of C by specific IgM pentamer, and also subunits of IgM, while kappa L chains act via another C-independent but mast cell-dependent pathway... - Risperidone-related improvement of irritability in children with autism is not associated with changes in serum of epidermal growth factor and interleukin-13Zuzana Tobiasova
Department of Immunobiology, New Haven, CT 06520, USA
J Child Adolesc Psychopharmacol 21:555-64. 2011..Whether altered levels of EGF and IL-13 play a role in the pathogenesis or phenotype of autism requires further investigation... - Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient miceChristin M Lepus
Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06509, USA
Hum Immunol 70:790-802. 2009.... - Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome casesAstrid Morer
Department of Immunobiology, Child Study Center of Yale University School of Medicine, New Haven, CT, USA
Brain Behav Immun 24:1069-73. 2010..For validation purposes, we determined expression of three genes that were previously reported to be elevated in post-mortem specimen of other TS cases: protein tyrosine phosphatase receptor-N (PTPR-N), PTPR-U and recoverin... - Peroxisome proliferator-activated receptor-? agonists prevent in vivo remodeling of human artery induced by alloreactive T cellsZuzana Tobiasova
Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
Circulation 124:196-205. 2011..Studies in rodents suggest that PPAR? agonists may inhibit graft vascular rejection, but human T-cell responses to allogeneic vascular cells differ from those in rodents, and the effects of PPAR? in human transplantation are unknown... - B-1 B cells mediate required early T cell recruitment to elicit protein-induced delayed-type hypersensitivityMarian Szczepanik
Department of Human Developmental Biology, Jagiellonian University College of Medicine, Krakow, Poland
J Immunol 171:6225-35. 2003..This stimulates C5a receptors on mast cells to release vasoactive substances, leading to endothelial activation for the 2-h DTH-initiating response, allowing local recruitment of DTH-effector T cells... - B cell-dependent T cell responses: IgM antibodies are required to elicit contact sensitivityRyohei F Tsuji
Noda Institute for Scientific Research, Chiba-ken 278, Japan
J Exp Med 196:1277-90. 2002..The IgM and challenge antigen likely form local complexes that activate complement, generating C5a, leading to local vascular activation to recruit the antigen-primed effector T cells that mediate the CS response...