Research Topics
Species | John S GiulianoSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Excess circulating angiopoietin-2 levels in sepsis: harbinger of death in the intensive care unit?John S Giuliano
Department of Pediatrics, Division of Critical Care Medicine, Yale University School of Medicine, Yale New Haven Children s Hospital, New Haven, CT 06510, USA
Crit Care 13:114. 2009..It remains to be seen whether angpt-2 levels will function solely as an early marker of sepsis or whether the manipulation of the angpt/Tie-2 system will become a rational therapeutic target for the management of sepsis...
Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypassJohn S Giuliano
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
Intensive Care Med 34:1851-7. 2008..The aim was to investigate the effects of cardiopulmonary bypass (CPB) on plasma levels of the vascular growth factors, angiopoietin (angpt)-1, angpt-2, and vascular endothelial growth factor (VEGF)...
The role of endogenously produced extracellular hsp72 in mononuclear cell reprogrammingPatricia A Abboud
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Shock 30:285-92. 2008..These data demonstrate that endogenously produced and released extracellular Hsp72 has the ability to reprogram the in vitro response to endotoxin in cultured human mononuclear cells...
Admission angiopoietin levels in children with septic shockJohn S Giuliano
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Shock 28:650-654. 2007..Given the contrasting effects of angpt-2 and angpt-1 on the vascular endothelium, these two factors may play an important role in the pathophysiology of septic shock in children, and further studies are warranted...
The immunomodulatory effects of albumin in vitro and in vivoDerek S Wheeler
Division of Critical Care Medicine, The Kindervelt Laboratory for Critical Care Medicine Research, Cincinnati Children s Research Foundation, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Adv Pharmacol Sci 2011:691928. 2011..Albumin preconditioning abrogated the LPS-mediated increase in NF-?B activation and TNF-? gene expression in vitro and in vivo. The clinical significance of these findings remains to be elucidated...
An infant with fever and stridorDerek S Wheeler
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
Pediatr Emerg Care 24:46-9. 2008..As illustrated in the following case, these children may not always present with classic features of supraglottitis...
