Suganthi Balasubramanian

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    Genome Biol 10:R2. 2009
  2. ncbi Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes
    Nathaniel Echols
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, Box 208114, New Haven, CT 06520-8114, USA
    Nucleic Acids Res 30:2515-23. 2002
  3. ncbi SNPs on human chromosomes 21 and 22 -- analysis in terms of protein features and pseudogenes
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520-8114, USA
    Pharmacogenomics 3:393-402. 2002
  4. ncbi Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University 266 Whitney Avenue, New Haven, CT 06520-8114, USA
    Nucleic Acids Res 33:1710-21. 2005
  5. ncbi Gene inactivation and its implications for annotation in the era of personal genomics
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, USA
    Genes Dev 25:1-10. 2011
  6. ncbi Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22
    Paul M Harrison
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, USA
    Genome Res 12:272-80. 2002

Detail Information

Publications6

  1. ncbi Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    Genome Biol 10:R2. 2009
    ..The availability of genome sequences of numerous organisms allows comparative study of pseudogenes in syntenic regions. Conservation of pseudogenes suggests that they might have a functional role in some instances...
  2. ncbi Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes
    Nathaniel Echols
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, Box 208114, New Haven, CT 06520-8114, USA
    Nucleic Acids Res 30:2515-23. 2002
    ..Our compositional analyses with the interactive viewer are available over the web at http://genecensus.org/pseudogene...
  3. ncbi SNPs on human chromosomes 21 and 22 -- analysis in terms of protein features and pseudogenes
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520-8114, USA
    Pharmacogenomics 3:393-402. 2002
    ..This could imply that protein structures, in general, can tolerate a wide degree of substitutions. Tables relating to our results are available from http://genecensus.org/pseudogene...
  4. ncbi Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University 266 Whitney Avenue, New Haven, CT 06520-8114, USA
    Nucleic Acids Res 33:1710-21. 2005
    ..Overall, we identify 115 SNPs in GPCRs from dbSNP that are likely to be associated with disease and thus are good candidates for genotyping in association studies...
  5. ncbi Gene inactivation and its implications for annotation in the era of personal genomics
    Suganthi Balasubramanian
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, USA
    Genes Dev 25:1-10. 2011
    ..In addition, we call for the development of an expanded gene set to include human-specific genes that have arisen recently and are absent from the ancestral set...
  6. ncbi Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22
    Paul M Harrison
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, USA
    Genome Res 12:272-80. 2002
    ..Finally, we find that chromosome 22 pseudogene population is dominated by immunoglobulin segments, which have a greater rate of disablement per amino acid than the other pseudogene populations and are also substantially more diverged...