Andrea Hoffmann

Summary

Affiliation: Wright State University
Country: USA

Publications

  1. ncbi Characterization of two polyclonal peptide antibodies that recognize the carboxy terminus of angiotensin II AT1A and AT1B receptors
    Andrea Hoffmann
    Department of Pharmacology and Toxicology, Wright State University School of Medicine, Dayton, Ohio 45435, USA
    Clin Exp Pharmacol Physiol 32:936-43. 2005
  2. ncbi Role of platelet-rich plasma in acceleration of bone fracture healing
    Richard Simman
    Department of Surgery, Division of Plastic Surgery, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA
    Ann Plast Surg 61:337-44. 2008
  3. ncbi Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain
    Yanfang Chen
    Department of Pharmacology and Toxicology, Wright State University Boonshoft School of Medicine, Dayton, OH 45435, USA
    Hypertension 47:230-7. 2006
  4. ncbi Angiotensin II receptor types 1A, 1B, and 2 in murine neuroblastoma Neuro-2a cells
    Andrea Hoffmann
    Department of Pharmacology and Toxicology, Wright State University, Dayton, Ohio 45435, USA
    J Recept Signal Transduct Res 23:111-21. 2003
  5. ncbi Advanced molecular profiling in vivo detects novel function of dickkopf-3 in the regulation of bone formation
    Hadi Aslan
    Skeletal Biotechnology Laboratory, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    J Bone Miner Res 21:1935-45. 2006
  6. ncbi Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells
    Andrea Hoffmann
    Signaling and Gene Regulation, Gesellschaft fur Biotechnologische Forschung GBF, Braunschweig, Germany
    J Clin Invest 116:940-52. 2006
  7. ncbi Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2)
    Christian Kaps
    Signaling and Gene Regulation, Gesellschaft fur Biotechnologische Forschung, Braunschweig, Germany
    Biofactors 20:71-84. 2004
  8. ncbi Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli
    Luis Felipe Vallejo
    Biochemical Engineering Division, National Research Center for Biotechnology (GBF, Mascheroder Weg 1, 38124, Braunschweig, Germany
    J Biotechnol 94:185-94. 2002
  9. ncbi Development of an enzyme-linked immunoreceptor assay (ELIRA) for quantification of the biological activity of recombinant human bone morphogenetic protein-2
    Janine Wendler
    Department of Natural Product Biology, National Research Centre for Biotechnology (GBF, Mascheroder Weg 1, 38124 Braunschweig, Germany
    J Biotechnol 119:425-35. 2005
  10. ncbi In vitro study on the dimensional accuracy of selected materials for monophase elastic impression making
    Andree Piwowarczyk
    Department of Prosthetic Dentistry, School of Dentistry, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Int J Prosthodont 15:168-74. 2002

Collaborators

Detail Information

Publications15

  1. ncbi Characterization of two polyclonal peptide antibodies that recognize the carboxy terminus of angiotensin II AT1A and AT1B receptors
    Andrea Hoffmann
    Department of Pharmacology and Toxicology, Wright State University School of Medicine, Dayton, Ohio 45435, USA
    Clin Exp Pharmacol Physiol 32:936-43. 2005
    ....
  2. ncbi Role of platelet-rich plasma in acceleration of bone fracture healing
    Richard Simman
    Department of Surgery, Division of Plastic Surgery, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA
    Ann Plast Surg 61:337-44. 2008
    ..Our results suggest that PRP accelerates bone fracture healing of rat femurs via modulation of TGF-beta1 and BMP-2 growth factor expression...
  3. ncbi Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain
    Yanfang Chen
    Department of Pharmacology and Toxicology, Wright State University Boonshoft School of Medicine, Dayton, OH 45435, USA
    Hypertension 47:230-7. 2006
    ..Results demonstrate the use of the RNA interference method in site-directed silencing of gene expression and provide a method for the in vivo study of Ang AT1 receptor function...
  4. ncbi Angiotensin II receptor types 1A, 1B, and 2 in murine neuroblastoma Neuro-2a cells
    Andrea Hoffmann
    Department of Pharmacology and Toxicology, Wright State University, Dayton, Ohio 45435, USA
    J Recept Signal Transduct Res 23:111-21. 2003
    ..We conclude that Neuro-2a cells represent an interesting model cell line for study of mechanisms that control the interplay between these receptors...
  5. ncbi Advanced molecular profiling in vivo detects novel function of dickkopf-3 in the regulation of bone formation
    Hadi Aslan
    Skeletal Biotechnology Laboratory, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    J Bone Miner Res 21:1935-45. 2006
    ..Among these genes the dickkopf homolog 3 (Dkk3) was upregulated and further studies showed that its expression affects in vitro and in vivo osteogenesis. This study indicates a possible role of Dkk3 in regulating bone formation...
  6. ncbi Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells
    Andrea Hoffmann
    Signaling and Gene Regulation, Gesellschaft fur Biotechnologische Forschung GBF, Braunschweig, Germany
    J Clin Invest 116:940-52. 2006
    ..These findings may have considerable importance for the therapeutic replacement of tendons or ligaments and for engineering other tissues in which BMP plays a pivotal developmental role...
  7. ncbi Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2)
    Christian Kaps
    Signaling and Gene Regulation, Gesellschaft fur Biotechnologische Forschung, Braunschweig, Germany
    Biofactors 20:71-84. 2004
    ..In addition this indicates that type IB and IA BMP receptors may transmit different signals during the specification and differentiation of mesenchymal lineages...
  8. ncbi Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli
    Luis Felipe Vallejo
    Biochemical Engineering Division, National Research Center for Biotechnology (GBF, Mascheroder Weg 1, 38124, Braunschweig, Germany
    J Biotechnol 94:185-94. 2002
    ..The purified rhBMP-2 dimer showed biological activity equivalent to CHO produced rhBMP-2 as tested by the induction of alkaline phosphatase activity in C2C12 cells...
  9. ncbi Development of an enzyme-linked immunoreceptor assay (ELIRA) for quantification of the biological activity of recombinant human bone morphogenetic protein-2
    Janine Wendler
    Department of Natural Product Biology, National Research Centre for Biotechnology (GBF, Mascheroder Weg 1, 38124 Braunschweig, Germany
    J Biotechnol 119:425-35. 2005
    ....
  10. ncbi In vitro study on the dimensional accuracy of selected materials for monophase elastic impression making
    Andree Piwowarczyk
    Department of Prosthetic Dentistry, School of Dentistry, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Int J Prosthodont 15:168-74. 2002
    ..To isolate this parameter, a direct measurement of the impressions was made without taking the model material into consideration...
  11. ncbi The T-box transcription factor Brachyury mediates cartilage development in mesenchymal stem cell line C3H10T1/2
    Andrea Hoffmann
    Osteo Angiogenesis Group, Gesellschaft fur Biotechnologische Forschung GBF, Mascheroder Weg 1, 38124 Braunschweig, Germany
    J Cell Sci 115:769-81. 2002
    ..5 d.p.c.) of murine embryonic development...
  12. ncbi Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors
    Andrea Hoffmann
    Gesellschaft fur Biotechnologische Forschung, Signal Transduction and Gene Regulation, Mascheroder Weg 1, 38124 Braunschweig, Germany
    J Biol Chem 280:27271-83. 2005
    ..Both synergistic and interfering influences of TAK1 on BMP-mediated Smad-signaling have been reported previously. We suggest that TAK1 is a factor that is involved in the fine-tuning of BMP effects during osteogenic development...
  13. ncbi Phosphonic acid monolayers for binding of bioactive molecules to titanium surfaces
    Nina Adden
    , Abt. TC Makromolekularer Stoffe, , Hans-Sommer-Strasse 10, 38106 Braunschweig, Germany
    Langmuir 22:8197-204. 2006
    ..Each step of the surface modification procedure was characterized by X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry...
  14. ncbi The biological effects of cell-delivered brain-derived neurotrophic factor on cultured spiral ganglion cells
    Athanasia Warnecke
    Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany
    Neuroreport 18:1683-6. 2007
    ..As a result, improved survival and neurite outgrowth was observed on SGCs. Our results demonstrate that lentivirally infected fibroblasts produce BDNF that has neurotrophic effects on spiral ganglions...
  15. ncbi Fibroblast-mediated delivery of GDNF induces neuronal-like outgrowth in PC12 cells
    Kirsten Wissel
    Department of Otolaryngology, Medical School of Hannover, Hannover, Germany
    Otol Neurotol 29:475-81. 2008
    ..Recombinantly modified cells deliver neurotrophic factors with the capacity to induce differentiation and the outgrowth of neurites of rat pheochromocytoma cells 12 (PC12) serving as a neuronal model...