Research Topics
Species | Monica R McClainSummaryAffiliation: Women and Infants Hospital Country: USA Publications
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Detail Information
Publications
A rapid-ACCE review of CYP2C9 and VKORC1 alleles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleedingMonica R McClain
Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Warren Alpert School of Medicine of Brown University, Providence, Rhode Island 02903, USA
Genet Med 10:89-98. 2008..Summarize evidence regarding genetic testing in adults to inform warfarin dosing to reduce adverse drug events such as serious bleeding...
Screen positive rates among six family history screening protocols for breast/ovarian cancer in four cohorts of womenMonica R McClain
Department of Pathology, Women and Infants Hospital Brown University, 70 Elm Street, 2nd Floor, Providence, Rhode Island 02903, USA
Fam Cancer 7:341-5. 2008..9% to 4.0%. Used alone, none of the recommended family history protocols yields an acceptable screen positive rate. A more acceptable 2% to 4% screen positive rate can be expected when all six protocols agree...
Variability in thyroid-stimulating hormone suppression by human chorionic [corrected] gonadotropin during early pregnancyJames E Haddow
The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
J Clin Endocrinol Metab 93:3341-7. 2008..The objective of the study was to further explore relationships between human chorionic gonadotropin (hCG), TSH, and free T4 in pregnant women at 11 through 18 wk gestation...
Thyroperoxidase and thyroglobulin antibodies in early pregnancy and preterm deliveryJames E Haddow
Women and Infants Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, USA
Obstet Gynecol 116:58-62. 2010..To further evaluate the relationship between thyroid antibodies and preterm births...
Thyroperoxidase and thyroglobulin antibodies in early pregnancy and placental abruptionJames E Haddow
Division of Medical Screening and Special Testing, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
Obstet Gynecol 117:287-92. 2011..To estimate the relationship between thyroid antibodies and placental abruption...
Sequential first- and second-trimester TSH, free thyroxine, and thyroid antibody measurements in women with known hypothyroidism: a FaSTER trial studyMonica R McClain
Warren Alpert Medical School, Brown University, Providence, RI 02903, USA
Am J Obstet Gynecol 199:129.e1-6. 2008..The purpose of this study was to examine how closely hypothyroidism management in the general pregnancy population satisfies recently issued guidelines and to determine whether improvements are indicated...
Urine iodine measurements, creatinine adjustment, and thyroid deficiency in an adult United States populationJames E Haddow
Division of Medical Screening, Women and Infants Hospital, 70 Elm Street, 2nd Floor, Providence, Rhode Island 02903, USA
J Clin Endocrinol Metab 92:1019-22. 2007..S. adults with the aim of determining whether low urine iodine is associated with thyroid deficiency...
Thyroid-stimulating hormone in singleton and twin pregnancy: importance of gestational age-specific reference rangesJames E Haddow
Obstet Gynecol 107:205-6; author reply 206. 2006
Mutation detection in the ABCC6 gene and genotype-phenotype analysis in a large international case series affected by pseudoxanthoma elasticumEllen G Pfendner
GeneDx Inc, 207 Perry Parkway, Gaithersburg, Maryland 20877, USA
J Med Genet 44:621-8. 2007..It is caused by mutations in the ABCC6 (ATP binding cassette family C member 6) gene, which encodes MRP6 (multidrug resistance-associated protein 6)...
How reliable are BRCA1/2 mutation estimates?Monica R McClain
Cancer Res 67:5057; author reply 5057-8. 2007
Screen-positive rates and agreement among six family history screening protocols for breast/ovarian cancer in a population-based cohort of 21- to 55-year-old womenGlenn E Palomaki
Foundation for Blood Research, Scarborough, ME, USA
Genet Med 8:161-8. 2006..One way to achieve this would be to require that multiple screening protocols agree...
Screening for thyroid disorders during pregnancy: results of a survey in MaineJames E Haddow
Foundation for Blood Research, Scarborough, ME, USA
Am J Obstet Gynecol 194:471-4. 2006..5 and 5.5 mU/L. CONCLUSION: Prenatal screening for thyroid deficiency varies among practices, reflecting conflicting guidelines. TSH cut-offs are also variable and might benefit from standardization...
Is first trimester measurement of sex hormone binding globulin a possible screening test for gestational diabetes mellitusMonica R McClain
Am J Obstet Gynecol 190:1808-9;author reply 1809. 2004
Trends in the diabetes quality improvement project measures in Maine from 1994 to 1999Monica R McClain
Maine Medical Assessment Foundation, Manchester, Maine, USA
Diabetes Care 26:597-601. 2003..To examine changes in the management of patients with diabetes from 1994 to 1999 using the claims-based Diabetes Quality Improvement Project (DQIP) accountability measures...
