Elisabeth J Cohen

..To determine the risk factors, clinical characteristics, treatments, and outcomes of patients with AK...

..To report a series of patients with no previous history of herpes simplex virus (HSV) infection who had new onset of herpetic keratitis after penetrating keratoplasty (PK)...

..To assess the impact of the different types of contact lenses (CLs) on quality of life (QoL) in patients with keratoconus based on self-reported results from The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire...

..To test the hypothesis that patients with keratoconus and pellucid who have glaucoma or are glaucoma suspects have lower corneal hysteresis (CH) and/or corneal resistance factor (CRF) measurements compared with controls...

..To evaluate the outcomes of the Boston Keratoprosthesis (KPro) at our institution...

..Prompt medical therapy results in a good clinical response in the majority of cases...

..To report a series of 5 patients with soft contact lens (SCL) related fungal keratitis caused by unusual organisms diagnosed at the Wills Eye Institute, Cornea Service in 2008...

..To review the symptoms, findings, and management options in patients referred to the Cornea Service who were unsatisfied with results after laser in situ keratomileusis (LASIK)...

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..To describe the clinical characteristics, time of presentation, risk factors, treatment, outcomes, and prognostic factors on a recent series of Acanthamoeba keratitis (AK) treated at our institution...

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..CONCLUSIONS: In this study, DB polishing was shown to be an effective and safe treatment for decreased vision caused by to ABMD over an average follow-up of 21.8 months...

..Patients should be carefully screened for ABMD. Those who have ABMD signs or symptoms may not be ideal candidates for LASIK...

..To determine the in vitro susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococcus (MRCNS) isolates to various antibiotics...

..Fortunately, progression to graft failure can usually be prevented if treatment is started promptly and intensively...

..The purposes of this study were to report the indications, graft survival, risk factors for graft failure, and visual outcomes for third or greater penetrating keratoplasties (PKP)...

..6). No clinical signs of systemic or local toxicity were seen with the topical CsA treatment. CONCLUSIONS: Two percent topical CsA is safe and effective in reducing the risk of allograft rejection in pediatric recipients...

..To compare the incidence and characteristics of graft rejection in keratoconus patients with and without self-reported atopy...

..To report the first case of fungal keratitis caused by presumed Carpoligna species...

..To describe nine patients with fungal keratitis refractory to standard antifungal therapy whose condition was managed with voriconazole...

..01). RK4 lenses were successfully worn full time or part time in all cases. CONCLUSIONS: The RK4 lens can provide well-tolerated visual correction in cases with central flat, peripheral steep corneal contour following PK...

..To identify current indications and trends in indications for penetrating keratoplasty (PKP) and associated procedures...

..To report the concomitant presentation of keratoconus and corneal dystrophies at Wills Eye Hospital for the 10-year period from January 1, 1997, to December 31, 2006...

..To report the outcomes of contact lens-intolerant patients with keratoconus (KCN) with subepithelial nodules treated with excimer laser phototherapeutic keratectomy (PTK)...

..To evaluate the incidence, history, symptoms, clinical signs, and treatment outcomes of blepharokeratoconjunctivitis in a pediatric population at a tertiary cornea practice...

..Further prospective studies are required to confirm the long-term efficacy of DB treatment in the management of recurrent corneal erosions associated with ABM dystrophy...

..CONCLUSIONS: Patients with corneal transplants have a life-long risk for wound dehiscence. This complication may be reduced by the regular use of eye protection in all corneal transplantation patients...

..He recovered good visual acuity in this eye with a rigid gas-permeable lens. This case shows the importance of selecting the appropriate agent in fungal keratitis...

..To assess the risk and incidence of rejection in patients who underwent bilateral penetrating keratoplasty (PK) and had at least one rejection episode...

..In patients with clear grafts and visually significant cataracts, cataract extraction alone is preferred over repeat penetrating keratoplasty and cataract extraction...

..This study was designed to determine the demographics of patients aged 50 years or more with a diagnosis of keratoconus, who were seen on the Cornea Service at Wills Eye Hospital...

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..To report trends in fungal keratitis from a single institution between 1999 and 2008...

..To discuss the initial results of fitting SynergEyes hybrid contact lenses (SynergEyes, Inc, Carlsbad, CA) for keratoconus (KC) and pellucid marginal degeneration (PMD)...

..DCT gave significantly higher IOP readings than GAT and TP in this study. DCT readings were not affected by corneal thickness. DCT may be more accurate in IOP measurement in eyes with KC and PMD...

..CONCLUSION: Antiviral prophylaxis for HSV recurrences was more effective in reducing infections in atopics and less effective in reducing inflammatory episodes in atopics versus nonatopics...

..To study the clinical course of herpes zoster ophthalmicus (HZO) and to compare the demographics, treatments, and outcomes in patients aged <60 years versus patients aged ?60 years at the time of diagnosis...

..3 +/- 5.5 months in group 1 and 37.3 +/- 6.3 months in group 2 (P =.001). CONCLUSIONS: Long-term oral acyclovir use seems to remain effective in decreasing the number of ocular herpes simplex virus recurrences beyond 12 months...

..An RK4 lens fitting is an alternative method for correcting postoperative irregular astigmatism and to achieve the best-corrected visual acuity...

..Poor best-corrected visual acuity at presentation of 0.2 (20/100) or worse and long follow-up (8 years or more) were significantly associated with surgery...

..Recurrence is infrequent in macular and Schnyder's crystalline dystrophy. As expected, in genetic diseases, the potential for recurrence exists and increases with follow-up time...

..Corticosteroids are the mainstay of treatment, with extended-wear contact lens and topical cyclosporine reserved as secondary agents...

..7%) eyes of 13 patients, who were still wearing DILs at the last follow-up. CONCLUSIONS: DILs may be a good alternative in selected patients with flat central and superior corneas and inferior peripheral steepening...

..CONCLUSIONS: A finding of inferior steepening on corneal topography examination should be regarded as a contraindication to the LASIK procedure...

..To report the results of Boston keratoprosthesis in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)...

..Keratoconus, Fuchs dystrophy, and other inherited diseases have remained consistent indications for keratoplasty during the last quarter century...

..We report 4 cases of corneal ulcers associated with drug abuse. The pathogenesis of these ulcers and management of these patients are also reviewed...

..Contact lens-related corneal ulcers continue to be a serious problem despite a shift in the market to the use of frequent-replacement daily-wear contact lenses and advances in contact lens technology...

..The percentage of PBK cases associated with PC IOLs has increased significantly, whereas the percentage associated with AC IOLs has decreased. The frequency of regraft has also increased significantly...

..The presence of scarring and high keratometry values at initial presentation may help to predict the likelihood of requiring a PK and may aid in patient counseling...

..CONCLUSION: Chelation with EDTA is an effective treatment of CBK. Visual acuity improves most in eyes with acuity between 20/50 and 20/400. This treatment can be used as the initial surgical intervention after conservative measures fail...

..Medical treatment seems to be adequate in many cases and may be appropriate initial therapy. When needed, SF(6) gas injection may also be successful, but not in all cases...

..To test the hypothesis that keratoconus and pellucid patients who have glaucoma or are suspected of having glaucoma have lower corneal hysteresis (CH) and/or corneal resistance factor (CRF) measurements compared to controls...

..Copper deposits at the level of Descemet's membrane may be a finding in a patient with monoclonal gammopathy of undetermined significance...

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..Eight grafts failed during the follow-up period. CONCLUSION: The importance of this study is to share our experience with this rare entity, congenital corneal opacities, describing their clinical presentation and their management...

..Fungal infection can be difficult to eradicate even with traditional antifungals. Although not approved for ophthalmic use yet, voriconazole provided improvement with Alternaria keratitis unresponsive to amphotericin...

..To validate photographic bioimaging for evaluating the severity of herpes simplex virus keratitis...

..Eye-bank records should be kept indefinitely because CJD may occur decades after iatrogenic exposure...

..Repair of the corneal laceration and removal of the intraocular foreign body after LASIK were managed without complications. Care must be taken to try not to manipulate or lift the LASIK flap during corneal laceration repair...

..Topical amikacin and systemic trimethoprim-sulfamethoxazole are effective drugs in the treatment of nocardial corneal infection with scleral involvement...

..To further characterize the mutations within the CHST6 gene responsible for causing macular corneal dystrophy in a cohort of affected patients from the United States...

..To describe a case in which the recognition by the ophthalmologist of Kayser-Fleischer rings played a crucial role in the diagnosis of Wilson disease (hepatolenticular degeneration)...

..To report two cases of Descemet membrane detachment associated with hemorrhage after alkali burn to the cornea...

..However, spontaneous extrusion of silicone plug occurs commonly. Careful choosing of the optimal plug size and close follow-up are recommended to ensure the success of the treatment...

..To compare the incidence of herpes simplex virus (HSV) epithelial recurrence and graft survival after penetrating keratoplasty (PK) in patients with and without self-reported atopy...

..To compare the characteristics of ocular herpes simplex virus (HSV) in patients with and without atopy...

..To report an outbreak of Fusarium keratitis in contact lens (CL) wearers in the northeastern United States...