STEPHEN DEVOTO

Summary

Affiliation: Wesleyan University
Country: USA

Publications

  1. ncbi Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish
    S H Devoto
    Biology Department, Wesleyan University, Middletown, CT 06457, USA
    Evol Dev 8:101-10. 2006
  2. ncbi Growth in the larval zebrafish pectoral fin and trunk musculature
    Sara E Patterson
    Department of Biology, Wesleyan University, Middletown, Connecticut 06459, USA
    Dev Dyn 237:307-15. 2008
  3. ncbi Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation
    Xuesong Feng
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Dev Biol 300:736-46. 2006
  4. ncbi Dynamic somite cell rearrangements lead to distinct waves of myotome growth
    Frank Stellabotte
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Development 134:1253-7. 2007

Research Grants

  1. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN DEVOTO; Fiscal Year: 2007
  2. Selecting for novel Hedgehog signaling mutations
    STEPHEN DEVOTO; Fiscal Year: 2006
  3. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN DEVOTO; Fiscal Year: 2003
  4. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN HENRI DEVOTO; Fiscal Year: 2010

Collaborators

  • P Steinbacher
  • Xuesong Feng
  • Sara E Patterson
  • Frank Stellabotte
  • Louisa B Mook
  • Betsy Dobbs-McAuliffe
  • Daniel A Fernández
  • Eric G Adiarte

Detail Information

Publications4

  1. ncbi Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish
    S H Devoto
    Biology Department, Wesleyan University, Middletown, CT 06457, USA
    Evol Dev 8:101-10. 2006
    ..The identification of a dermomyotome in fish makes it possible to apply the powerful cellular and genetic approaches available in zebrafish to the understanding of this key developmental structure...
  2. ncbi Growth in the larval zebrafish pectoral fin and trunk musculature
    Sara E Patterson
    Department of Biology, Wesleyan University, Middletown, Connecticut 06459, USA
    Dev Dyn 237:307-15. 2008
    ..Our results suggest that regulation of fiber type development and muscle growth may differ in the pectoral fin and trunk...
  3. ncbi Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation
    Xuesong Feng
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Dev Biol 300:736-46. 2006
    ..We propose that Hedgehog signaling acts at multiple times on different lineages, through different downstream pathways, to promote myogenic differentiation...
  4. ncbi Dynamic somite cell rearrangements lead to distinct waves of myotome growth
    Frank Stellabotte
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Development 134:1253-7. 2007
    ..The surprising movement of the anterior somite cells to the external somite surface transforms a segmentally repeated arrangement of myogenic precursors into a medio-lateral arrangement similar to that seen in amniotes...

Research Grants16

  1. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN DEVOTO; Fiscal Year: 2007
    ..When the signals regulating myogenesis are understood, it will be possible to guide stem cells towards a myogenic fate, to design therapies for devastating human diseases. ..
  2. Selecting for novel Hedgehog signaling mutations
    STEPHEN DEVOTO; Fiscal Year: 2006
    ..In addition, these mutations will identify genes that are likely to play important roles in the development of human cancer. ..
  3. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN DEVOTO; Fiscal Year: 2003
    ..We will block cells from responding to BMP4-type proteins by expressing a dominant negative BMP4 receptor. We will ectopically activate BMP4 signaling by expressing an activated BMP4 receptor. ..
  4. DEVELOPMENT OF MUSCLE FIBER TYPE IDENTITY
    STEPHEN HENRI DEVOTO; Fiscal Year: 2010
    ..When the signals regulating myogenesis are understood, it will be possible to guide stem cells towards a myogenic fate, to design therapies for devastating human diseases. ..