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Genomes and Genes | Hind NassarSummaryAffiliation: Wayne State University Country: USA Publications
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Publications
Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoproteinHind Nassar
Department of Pathology, Wayne State University, Harper University Hospital Detroit, MI 48201, USA
Mod Pathol 17:1045-50. 2004....- Carcinomas with micropapillary morphology: clinical significance and current conceptsHind Nassar
Department of Pathology at Wayne State University, Harper University Hospital and the Karmanos Cancer Institute, Detroit, Michigan 48201, USA
Adv Anat Pathol 11:297-303. 2004..In this article the author reviews the available literature on tumors displaying a micropapillary component... - Clinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomasHind Nassar
Wayne State University Harper Hospital and Karmanos Cancer Institute, Detroit, MI, USA
Am J Surg Pathol 30:501-7. 2006..In conclusion, SPCs are heterogeneous lesions that arise in older women and have an indolent behavior. Lymph node and distant metastases are uncommon and generally limited to cases with (conventional) invasive components... - Heterogeneity of Bcl-2 expression in metastatic breast carcinomaAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
Mod Pathol 23:1089-96. 2010..Instead, downregulation of bcl-2 expression may occur in the setting of hormone therapy resistance. Our findings call into question the potential utility of anti-bcl-2 therapy in metastatic breast cancer... - The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpressionAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA
Mod Pathol 22:1423-31. 2009..As cancers using the ALT pathway are predicted to be resistant to therapies based on telomerase inhibition, these results may have therapeutic consequences... - Relationship between molecular subtype of invasive breast carcinoma and expression of gross cystic disease fluid protein 15 and mammaglobinGloria H Lewis
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Clin Pathol 135:587-91. 2011..Correlation with clinical findings may be needed to exclude the possibility of a metastasis to the breast when BLCs or UTNCs are encountered in a limited sample such as a core biopsy sample... - Pathogenesis of colloid (pure mucinous) carcinoma of exocrine organs: Coupling of gel-forming mucin (MUC2) production with altered cell polarity and abnormal cell-stroma interaction may be the key factor in the morphogenesis and indolent behavior of colloN Volkan Adsay
Department of Pathology, Karamanos Cancer Institute and Wayne State University, Detroit, Michigan 48201, USA
Am J Surg Pathol 27:571-8. 2003..This distinctive mucin, accumulated in the stroma surrounding the CC cells, may act as a containing factor, slackening the spread of the cells... - High-grade neuroendocrine carcinoma of the ampulla of vater: a clinicopathologic and immunohistochemical analysis of 14 casesHind Nassar
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 29:588-94. 2005..Thus, there are differences in the molecular phenotypes of these two types of ampullary carcinoma, supporting the distinction of poorly differentiated carcinomas with a neuroendocrine phenotype from those without... - Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironmentDonald R Schwartz
Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA
Mol Cancer Res 5:443-54. 2007.... - Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literatureN Volkan Adsay
Department of Pathology, The Karmanos Cancer Institute and Wayne State University, Harper Hospital, 3990 John R Street, Detroit, MI 48201, USA
Virchows Arch 444:527-35. 2004..These are predominantly hematopoietic malignancies or carcinomas of renal or gastric origin. Secondary tumors should be entertained in both the clinical and pathological differential diagnosis of pancreatic neoplasia... - Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell deathMalathy P V Shekhar
Breast Cancer Program, Karmanos Cancer Institute, Department of Pathology, Wayne State University, Detroit, Michigan, USA
Cancer Biol Ther 7:1774-82. 2008..It is possible that spontaneous apoptosis facilitates elimination of cells thus permitting expansion and malignant transformation of cancer cells that are resistant to spontaneous apoptosis... - Incidental minimal atypical lobular hyperplasia on core needle biopsy: correlation with findings on follow-up excisionAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Surg Pathol 34:822-8. 2010..However, management of ALH is controversial. We review our experience with incidental minimal ALH on core biopsy, and correlate with excision and follow-up results... - Ductal carcinoma in situ in African American versus Caucasian American women: analysis of clinicopathologic features and outcomeHind Nassar
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Cancer 115:3181-8. 2009..The characteristics of ductal carcinoma in situ (DCIS) in the AA population have not been extensively studied... - MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumorsAatur D Singhi
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Mod Pathol 25:378-87. 2012..These observations underscore the importance of MYC in breast cancer progression/metastasis, as well as its relevance as a potential therapeutic target in otherwise incurable metastatic disease... - Most basal-like breast carcinomas demonstrate the same Rb-/p16+ immunophenotype as the HPV-related poorly differentiated squamous cell carcinomas which they resemble morphologicallyAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Medical Institutions, MD 21231 2410, USA
Am J Surg Pathol 33:163-75. 2009..This subset may represent a more homogenous group than BLC as defined currently... - Aberrant expression of X-linked genes RbAp46, Rsk4, and Cldn2 in breast cancerArchana Thakur
Department of Pathology, Karmanos Cancer Institute, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
Mol Cancer Res 5:171-81. 2007..The activation status of the X-chromosome may influence the expression levels of X-linked oncogenes or tumor suppressor genes... - The major autopsy findings in adult patients after hematopoietic stem cell transplantationSaid Khayyata
Department of Pathology, Harper University Hospital, Wayne State University, Detroit, MI, USA
Ann Transplant 12:11-8. 2007..Hematopoietic stem cell transplantation (HSCT) is a curative treatment option for hematological malignancies, but this treatment can be associated with a mortality risk...