Research Topics
| Parth B AminSummaryAffiliation: Wayne State University Country: USA Publications
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Publications
Ethanol effects proinflammatory state of neutrophils in shockParth B Amin
Department of Surgery, Wayne State University University Health Center, Detroit, Michigan 48201, USA
J Surg Res 142:250-5. 2007..The ability of gut derived factors on neutrophil function in this setting is unknown. This study looks at the role of ethanol in modulating proinflammatory states in the neutrophil in vitro...
The synergistic effect of ethanol and shock insults on Caco-2 cytokine production and apoptosisParth B Amin
Department of Surgery, Wayne State University University Health Center, Detroit, Michigan 48201, USA
Shock 29:631-5. 2008..Ethanol and H/R have a synergistic effect on cytokine production and barrier dysfunction in this model. They may also contribute to increased infectious complications and posttraumatic organ failure...
Secretory immunoglobulin a blunts gut-mediated priming of neutrophils in vitroParth B Amin
Department of Surgery, Wayne State University University Health Center, Detroit, Michigan, USA
J Trauma 64:1437-42. 2008..We hypothesized that sIgA would blunt the gut-mediated priming events that lead to neutrophil hypersensitivity to bacterial challenge...
Dose-dependent effects of ethanol and E. coli on gut permeability and cytokine productionParth B Amin
Department of Surgery, Wayne State University, Detroit, Michigan 48201, USA
J Surg Res 157:187-92. 2009..We hypothesized that even low concentrations of EtOH would cause significant cytokine release and barrier dysfunction in vitro...
Benign fibroepithelial polyp arising in the bronchus: a case report and review of the literatureParth B Amin
Department of Surgery, Wayne State University and Detroit Medical Center, Detroit, Michigan, USA
Arch Surg 144:1081-3. 2009..We present the clinical history of this patient along with a brief review of the published literature regarding this rare clinical entity...
The intestinal epithelial cell modulates the effect of alcohol on neutrophil inflammatory potentialParth B Amin
Department of Surgery, Wayne State University University Health Center 6 C, Detroit, Michigan, USA
J Trauma 63:1223-9. 2007..We studied the ability of intestinal epithelial cells and bacteria to modulate EtOH effects on polymorphonuclear (PMN) cell function in vitro...
Sequence of immunoglobulin isotype exposure modulates inflammatory response to bacteria and lipopolysaccharide in vitroLawrence N Diebel
Department of Surgery, Wayne State University, Detroit, Michigan 48201, USA
Surg Infect (Larchmt) 11:145-50. 2010..We examined the effect of the sequence of exposure to the two immunoglobulin isotypes on bacteria- or lipopolysaccharide (LPS)-mediated cytokine production by monocyte-polymorphonuclear neutrophil (PMN) cells in vitro...
Secretory immunoglobulin A abrogates inflammatory responses and improves mortality after pseudomonas pneumoniaParth B Amin
Department of Surgery, Wayne State University Detroit Medical Center, Detroit, Michigan 48201, USA
J Trauma 68:827-33. 2010..Polyimmunoglobulin receptor (pIgR) knockout (KO) mice, which do not have SIgA in mucosal secretions but are otherwise immunologically intact, were used to study the importance of SIgA in respiratory secretions after bacterial pneumonia...
Cleavage of SIgA by gram negative respiratory pathogens enhance neutrophil inflammatory potentialLawrence N Diebel
Department of Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
J Trauma 66:1336-42; discussion 1342. 2009..We postulate that SIgA cleavage by bacteria would also affect anti-inflammatory properties of IgA and studied this in vitro...
T-cell cytokines affect mucosal immunoglobulin A transportParth B Amin
Department of Surgery, Wayne State University, 4201 St Antoine St, Suite 6C, University Health Center, Detroit, MI 48201, USA
Am J Surg 194:128-33. 2007..The purpose of this study was to elucidate the role of the Th1-type cytokine, interferon gamma (IFN-gamma), and the Th2-type cytokine interleukin-4 (IL-4) on IgA transcytosis across intestinal epithelial cells in vitro...
