Lei Wang

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Validity of large-deformation high dimensional brain mapping of the basal ganglia in adults with Tourette syndrome
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychiatry Res 154:181-90. 2007
  2. ncbi Large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the Alzheimer type
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Ave, St Louis, MO 63110, USA
    IEEE Trans Med Imaging 26:462-70. 2007
  3. ncbi Abnormalities of cingulate gyrus neuroanatomy in schizophrenia
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 S Euclid Ave, St Louis, MO 63110, United States
    Schizophr Res 93:66-78. 2007
  4. ncbi Abnormalities of hippocampal surface structure in very mild dementia of the Alzheimer type
    Lei Wang
    Alzheimer s Disease Research Center and The Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Neuroimage 30:52-60. 2006
  5. ncbi Structural analysis of the basal ganglia in schizophrenia
    Daniel Mamah
    Department of Psychiatry, Washington University Medical School, St Louis, MO 63110, USA
    Schizophr Res 89:59-71. 2007
  6. ncbi Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients
    Daniel Mamah
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Biol Psychiatry 64:111-20. 2008
  7. ncbi Abnormalities of thalamic volume and shape in schizophrenia
    John G Csernansky
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 161:896-902. 2004
  8. ncbi Structural abnormalities in gyri of the prefrontal cortex in individuals with schizophrenia and their unaffected siblings
    Michael P Harms
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Br J Psychiatry 196:150-7. 2010
  9. ncbi Cingulate gyrus neuroanatomy in schizophrenia subjects and their non-psychotic siblings
    Daniel R Calabrese
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, United States
    Schizophr Res 104:61-70. 2008
  10. ncbi Thalamic shape abnormalities in individuals with schizophrenia and their nonpsychotic siblings
    Michael P Harms
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13835-42. 2007

Collaborators

Detail Information

Publications70

  1. ncbi Validity of large-deformation high dimensional brain mapping of the basal ganglia in adults with Tourette syndrome
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychiatry Res 154:181-90. 2007
    ..We found no significant volume or shape differences in any of the structures in this small sample of subjects...
  2. ncbi Large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the Alzheimer type
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Ave, St Louis, MO 63110, USA
    IEEE Trans Med Imaging 26:462-70. 2007
    ..Further, PCA of the initial momentum leads to correct classification of 12 out of 18 DAT subjects and 22 out of 26 control subjects...
  3. ncbi Abnormalities of cingulate gyrus neuroanatomy in schizophrenia
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 S Euclid Ave, St Louis, MO 63110, United States
    Schizophr Res 93:66-78. 2007
    ....
  4. ncbi Abnormalities of hippocampal surface structure in very mild dementia of the Alzheimer type
    Lei Wang
    Alzheimer s Disease Research Center and The Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Neuroimage 30:52-60. 2006
    ..Neurology 55, 1636--1643.] and suggest that inward deformities of the hippocampal surface in proximity to the CA1 subfield and subiculum can be used to distinguish subjects with very mild DAT from nondemented subjects...
  5. ncbi Structural analysis of the basal ganglia in schizophrenia
    Daniel Mamah
    Department of Psychiatry, Washington University Medical School, St Louis, MO 63110, USA
    Schizophr Res 89:59-71. 2007
    ..In conclusion, basal ganglia volumes relative to total brain volume were larger in schizophrenia subjects than healthy comparison subjects. Specific patterns of shape change accompanied these volume differences...
  6. ncbi Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients
    Daniel Mamah
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Biol Psychiatry 64:111-20. 2008
    ..Our aim was to test the hypothesis that abnormalities of basal ganglia structure are intrinsic features of schizophrenia by assessing basal ganglia volume and shape in the unaffected siblings of schizophrenia subjects...
  7. ncbi Abnormalities of thalamic volume and shape in schizophrenia
    John G Csernansky
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 161:896-902. 2004
    ..However, the pattern of shape change associated with such volume loss has not been investigated. In this study, alterations in thalamic volume, shape, and symmetry were compared in subjects with and without schizophrenia...
  8. ncbi Structural abnormalities in gyri of the prefrontal cortex in individuals with schizophrenia and their unaffected siblings
    Michael P Harms
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Br J Psychiatry 196:150-7. 2010
    ..The relatives of individuals with schizophrenia exhibit deficits of overall frontal lobe volume, consistent with a genetic contribution to these deficits...
  9. ncbi Cingulate gyrus neuroanatomy in schizophrenia subjects and their non-psychotic siblings
    Daniel R Calabrese
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, United States
    Schizophr Res 104:61-70. 2008
    ....
  10. ncbi Thalamic shape abnormalities in individuals with schizophrenia and their nonpsychotic siblings
    Michael P Harms
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13835-42. 2007
    ..Inward deformation of the anterior and posterior regions of the thalamus represents a potential neuroanatomical endophenotype of schizophrenia...
  11. ncbi Changes in hippocampal volume and shape across time distinguish dementia of the Alzheimer type from healthy aging
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 20:667-82. 2003
    ..These results suggest that different patterns of hippocampal shape change in time as well as different rates of hippocampal volume loss distinguish very mild DAT from healthy aging...
  12. ncbi Anterior thalamic radiation integrity in schizophrenia: a diffusion-tensor imaging study
    Daniel Mamah
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, United States
    Psychiatry Res 183:144-50. 2010
    ..Microstructural changes in the ALIC may be linked to cognitive dysfunction in schizophrenia...
  13. ncbi High-dimensional mapping of the hippocampus in depression
    Joel A Posener
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 160:83-9. 2003
    ..In this study, high-dimensional brain mapping was used to evaluate hippocampal shape and volume in patients with major depressive disorder and healthy comparison subjects...
  14. ncbi Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia
    John G Csernansky
    Alzheimer s Disease Research Center and the Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Psychiatry 163:2164-9. 2006
    ....
  15. ncbi Neuroanatomical predictors of response to donepezil therapy in patients with dementia
    John G Csernansky
    Alzheimer s Disease Research Center, and Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Neurol 62:1718-22. 2005
    ..Patients with dementia of the Alzheimer type (DAT) respond variably to treatment with acetylcholinesterase inhibitors...
  16. ncbi MRI-based large deformation high dimensional mapping of the hippocampus in rats: development and validation of the technique
    R Edward Hogan
    The Department of Neurology, Washington University, St Louis, Missouri 63110, USA
    J Magn Reson Imaging 29:1027-34. 2009
    ..We report the development and validation of the application of large deformation high dimensional mapping (HDM-LD) segmentation for the hippocampus in the rat...
  17. ncbi Correlations between antemortem hippocampal volume and postmortem neuropathology in AD subjects
    John G Csernansky
    Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alzheimer Dis Assoc Disord 18:190-5. 2004
    ..The data suggest that hippocampal volume assessed in living subjects with probable AD is both a good marker of dementia severity and of an underlying element of the AD disease process...
  18. ncbi Computational anatomy and neuropsychiatric disease: probabilistic assessment of variation and statistical inference of group difference, hemispheric asymmetry, and time-dependent change
    John G Csernansky
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 23:S56-68. 2004
    ..g., asymmetry), and changes of shapes over time. Promising preliminary studies employing these approaches to studies of subjects with schizophrenia and very mild to mild Alzheimer's disease (AD) are presented...
  19. ncbi BDNF polymorphism rs6265 and hippocampal structure and memory performance in healthy control subjects
    Meghana S Karnik
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychiatry Res 178:425-9. 2010
    ..We concluded that in a large cohort of healthy human subjects, the Met allele of rs6265 is not associated with hippocampal structure or memory performance...
  20. ncbi Effects of age, sex, and independent life events on amygdala and nucleus accumbens volumes in child bipolar I disorder
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, Missouri 63110 1093, USA
    Biol Psychiatry 65:432-7. 2009
    ..Relationships between environment and cortical-limbic-striatal pathways are not well-researched in child bipolar I disorder (BP-I)...
  21. ncbi Hippocampal deformities in schizophrenia characterized by high dimensional brain mapping
    John G Csernansky
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Am J Psychiatry 159:2000-6. 2002
    ..High dimensional brain mapping, which utilizes probabilistic deformations of a neuroanatomical template, was used to characterize disease-related patterns of changes in hippocampal volume, shape, and asymmetry...
  22. ncbi Structural pathology underlying neuroendocrine dysfunction in schizophrenia
    Morris B Goldman
    Northwestern University, Department of Psychiatry, 446 East Ontario, Suite 7 100, Chicago, IL 60611, United States
    Behav Brain Res 218:106-13. 2011
    ..The relationship of these findings to the underlying mental illness remains to be established...
  23. ncbi MRI-based high-dimensional hippocampal mapping in mesial temporal lobe epilepsy
    R Edward Hogan
    Department of Neurology, Saint Louis University, 1221 S Grand, 1st Floor, Epilepsy Offices, St Louis, MO 63104, USA
    Brain 127:1731-40. 2004
    ..Contralateral hippocampi show different HDM-LD changes, suggesting that the underlying disease process in the contralateral hippocampi is different from MTS...
  24. ncbi Pathogenic cysteine mutations affect progranulin function and production of mature granulins
    Jun Wang
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurochem 112:1305-15. 2010
    ..Our data suggest that these mutations affect the function of full-length PGRN as well as elastase cleavage of PGRN into GRNs, leading to neurodegeneration...
  25. ncbi Abnormalities of thalamic volume and shape detected in fetally irradiated rhesus monkeys with high dimensional brain mapping
    Matthew K Schindler
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA
    Biol Psychiatry 51:827-37. 2002
    ..Low-dose irradiation of the fetal primate may be useful for modeling key features of the pathology described in schizophrenic patients...
  26. ncbi Feature extraction of mental task in BCI based on the method of approximate entropy
    Lei Wang
    Province Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin, China
    Conf Proc IEEE Eng Med Biol Soc 2007:1941-4. 2007
    ..Different results were gained from the mental task experiment and imagery movement experiment. The results show that Apen is an effective method to extract the feature of different brain states...
  27. ncbi Inter-rater reliability of manual segmentation of the superior, inferior and middle frontal gyri
    John P John
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Hosur Road, Bangalore 560 029, Karnataka, India
    Psychiatry Res 148:151-63. 2006
    ..97, 0.94 and 0.93, respectively. Thus, we describe a reliable method of parcellating the SFG, IFG and MFG, which constitute the DLPFC, a brain region involved in a variety of neuropsychiatric conditions...
  28. ncbi Abnormalities of thalamic activation and cognition in schizophrenia
    Jessica Andrews
    Department of Anatomy and Neurobiology, Washington University, St. Louis, MO 63130, USA
    Am J Psychiatry 163:463-9. 2006
    ....
  29. ncbi Response of risperidone treatment may be associated with polymorphisms of HTT gene in Chinese schizophrenia patients
    Lei Wang
    Bio X Center, Shanghai Jiao Tong University, Shanghai, China
    Neurosci Lett 414:1-4. 2007
    ....
  30. ncbi FreeSurfer-initiated fully-automated subcortical brain segmentation in MRI using Large Deformation Diffeomorphic Metric Mapping
    Ali R Khan
    School of Engineering Science, Simon Fraser University, 8888 University Drive, Burnaby BC, Canada V5A 1S6
    Neuroimage 41:735-46. 2008
    ..We also find statistically significant improvement of accuracy in FS+LDDMM over FreeSurfer for the caudate nucleus and putamen of Huntington's disease and Tourette's syndrome subjects, and the right hippocampus of Schizophrenia subjects...
  31. ncbi Feature selection with kernel class separability
    Lei Wang
    Research School of Information Sciences and Engineering, The Australian National University, RSISE, Canberra, ACT, Australia
    IEEE Trans Pattern Anal Mach Intell 30:1534-46. 2008
    ..This criterion is applied to a variety of selection modes with different search strategies. Extensive experimental study demonstrates its efficiency in delivering fast and robust feature selection...
  32. ncbi Association between a polymorphism of the HTR3A gene and therapeutic response to risperidone treatment in drug-naive Chinese schizophrenia patients
    Bo Gu
    Bio X Center, Shanghai Jiao Tong University, Fudan University, Shanghai, China
    Pharmacogenet Genomics 18:721-7. 2008
    ..We therefore postulated that such a polymorphism might be an explanatory factor in the diversity of response to risperidone treatment...
  33. ncbi Combining anatomical manifold information via diffeomorphic metric mappings for studying cortical thinning of the cingulate gyrus in schizophrenia
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore 117576
    Neuroimage 37:821-33. 2007
    ..Subjects with schizophrenia had non-uniform cortical thinning over the left and right cingulate gyri, especially in the anterior portion, as compared to healthy comparison subjects...
  34. ncbi 3D reconstruction of head MRI based on one class support vector machine with immune algorithm
    Lei Wang
    Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province in Hebei University of Technology, Tianjin, China, 300130
    Conf Proc IEEE Eng Med Biol Soc 2007:6016-9. 2007
    ..The experimental results demonstrate OCSVM is effective with high reconstruction accuracy...
  35. ncbi Generalized 2D principal component analysis for face image representation and recognition
    Hui Kong
    School of Electrical and Electronic Engineering, Nanyang Technological University, Nanyang 639798, Singapore
    Neural Netw 18:585-94. 2005
    ..1998) is explored. Experimental results in face image representation and recognition show the excellent performance of G2DPCA...
  36. ncbi A criterion for optimizing kernel parameters in KBDA for image retrieval
    Lei Wang
    IEEE Trans Syst Man Cybern B Cybern 35:556-62. 2005
    ..Retrieval experiments on two benchmark image databases demonstrate the effectiveness of proposed criterion for KBDA to achieve the best possible performance at the cost of a small fractional computational overhead...
  37. ncbi Direct and indirect effects of fetal irradiation on cortical gray and white matter volume in the macaque
    Lynn D Selemon
    Department of Neurobiology, Yale University School of Medicine, PO Box 208001, New Haven, CT 06520 8001, USA
    Biol Psychiatry 57:83-90. 2005
    ..Exposure of nonhuman primates to x-irradiation in early gestation has previously been shown to decrease thalamic volume and neuronal number. Here we examine whether early gestational irradiation also results in cortical volume reduction...
  38. ncbi Ischemic cerebral tissue response to subventricular zone cell transplantation measured by iterative self-organizing data analysis technique algorithm
    Lian Li
    Department of Neurology, Henry Ford Health Sciences Center, Detroit, Michigan 48202, USA
    J Cereb Blood Flow Metab 26:1366-77. 2006
    ..Angiogenesis was present in sites either immediately adjacent to or surrounded by the grafted cells. Our data indicate that map-ISODATA accurately and dynamically characterizes the ischemic lesion and its response to cell therapy...
  39. ncbi Error analysis of pure rotation-based self-calibration
    Lei Wang
    Department of Computer Science and Technology, Tsinghua University, Beijing 100084, PR China
    IEEE Trans Pattern Anal Mach Intell 26:275-80. 2004
    ..Our analysis can be used to help choose the least error-prone approach (if multiple approaches exist) for a given set of conditions...
  40. ncbi Hippocampal deformities in the unaffected siblings of schizophrenia subjects
    Ralf Tepest
    Department of Psychiatry (RT, University of Bonn Medical Center, Bonn, Germany
    Biol Psychiatry 54:1234-40. 2003
    ..CONCLUSIONS: Deformations of hippocampal anatomy may be related to the genetic vulnerability of acquiring schizophrenia...
  41. ncbi Research on 3D modeling for head MRI image based on immune sphere-shaped support vector machine
    Lei Guo
    Province Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin, China
    Conf Proc IEEE Eng Med Biol Soc 2007:1082-5. 2007
    ..As our experiment demonstrates, the models are constructed and reach satisfactory modeling accuracies. Theory and experiment indicate ISSSVM exhibits its great potential in image 3D modeling...
  42. ncbi Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury
    Dunyue Lu
    Department of Neurosurgery, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Cell Transplant 11:275-81. 2002
    ..Some HUCB cells integrated into the vascular walls within the boundary zone of the injured area. Our data suggest that i.v. administration of HUCB may be useful in the treatment of TBI...
  43. ncbi Anomalous heat conduction and anomalous diffusion in nonlinear lattices, single walled nanotubes, and billiard gas channels
    Baowen Li
    Department of Physics, National University of Singapore, 117542 Singapore
    Chaos 15:15121. 2005
    ..Existing numerical data support our theoretical prediction...
  44. ncbi Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
    Lei Wang
    Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 100:1393-8. 2003
    ....
  45. ncbi Validation of semiautomated methods for quantifying cingulate cortical metrics in schizophrenia
    J Tilak Ratnanather
    Center for Imaging Science, The Johns Hopkins University, Clark 301, 3400 North Charles St, Baltimore, MD 21218, USA
    Psychiatry Res 132:53-68. 2004
    ..82. In addition, by repeating the entire procedure three times in one subject, we obtained a coefficient of variation of 0.0438 for surface area...
  46. ncbi ADC characterization of region-specific response to cerebral perfusion deficit in rats by MRI at 9.4 T
    Victor E Yushmanov
    Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Magn Reson Med 47:562-70. 2002
    ..A better understanding of the mechanisms linking ADC and CBF changes to ischemic cell disorders may prove useful in characterizing the degree of tissue damage, and in developing and evaluating treatment strategies...
  47. ncbi Analysis of glucose and lactate in hippocampal dialysates of rats during the operant conditioned reflex using microdialysis
    Yu Dong
    Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, 100080, Beijing, PR China
    Neurochem Int 43:67-72. 2003
    ..Compared with glucose, lactate can immediately indicate the dynamic changes in brain...
  48. ncbi Depth-resolved birefringence and differential optical axis orientation measurements with fiber-based polarization-sensitive optical coherence tomography
    Shuguang Guo
    Beckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA
    Opt Lett 29:2025-7. 2004
    ..Experimental results with beef tendon and rabbit tendon and muscle show that this technique has promising potential for imaging the birefringent structure of multiple-layer samples with varying optical axes...
  49. ncbi [Multi-variate regression analysis of clinicopathological characteristics and prognosis of colorectal cancer]
    Jian-Ping Wang
    Department of Gastrointestinopancreatic Surgery, First Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China
    Zhonghua Zhong Liu Za Zhi 25:59-61. 2003
    ..CONCLUSION: Dukes stage, as the most important available independent prognostic factor (P < 0.0005), is able to assess the postoperative survival...
  50. ncbi Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis
    Tao Su
    Herbert Irving Comprehensive Cancer Center and Integrated Program in Cellular, Molecular, and Biophysical Studies, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:7824-9. 2003
    ..Taken together, these findings suggest that, like FHIT, PKCI may normally play a tumor-suppressor role. The possible role of PKCI as a tumor suppressor in humans remains to be determined...
  51. ncbi In vivo magnetic resonance imaging tracks adult neural progenitor cell targeting of brain tumor
    Zhenggang Zhang
    Department of Neurology, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Neuroimage 23:281-7. 2004
    ....
  52. ncbi A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation
    Kwang H Ahn
    Department of Molecular and Cell Biology, University of Connecticut, Storrs, 06269, USA
    Brain Res 1108:1-11. 2006
    ..M., Ahn, K.H. and Kendall, D.A., 2006. Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization. Biochemistry, 45, 5606-5617)...
  53. ncbi Dopamine transporter polymorphisms and risperidone response in Chinese schizophrenia patients: an association study
    Aiping Zhang
    Shanghai Jiao Tong University, Bio X Center, Haoran Building, 1954 Huashan Road, Shanghai 200030, China
    Pharmacogenomics 8:1337-45. 2007
    ..Further studies on larger groups and on the effects of longer-term risperidone treatment are needed to confirm these results...
  54. ncbi Resistivity parameters estimation based on 2D real head model using improved differential evolution algorithm
    Ying Li
    Province Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin 300130, China
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..Furthermore, the selection of the amplification parameters is much easier...
  55. ncbi MRI detects white matter reorganization after neural progenitor cell treatment of stroke
    Quan Jiang
    Department of Neurology, Henry Ford Health Sciences Center, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Neuroimage 32:1080-9. 2006
    ..Our data demonstrate that FA and FT identify and characterize cerebral tissue undergoing white matter reorganization after stroke and treatment with neural progenitor cells...
  56. ncbi Increased hematopoietic stem cell mobilization in aged mice
    Zhenlan Xing
    Division of Experimental Hematology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Blood 108:2190-7. 2006
    ..These results might indicate that stroma-stem cell interactions are dynamic over a lifetime and result in physiologically relevant changes in the biology of primitive hematopoietic cells with age...
  57. ncbi [Designing and realization of the dynamic filter in B mode ultrasonic scanning]
    Lei Wang
    Department of Control Science and Engineering, Harbin Institute of Technology
    Zhongguo Yi Liao Qi Xie Za Zhi 30:372-4, 348. 2006
    ....
  58. ncbi A novel OPA1 mutation responsible for autosomal dominant optic atrophy with high frequency hearing loss in a Chinese family
    Suqin Chen
    Department of Medical Genetics, Zhongshan Medical College, Sun Yat Sen University, Guangzhou, P R China
    Am J Ophthalmol 143:186-188. 2007
    ..To investigate the genetic findings and phenotypic characters of autosomal dominant optic atrophy (ADOA)...
  59. ncbi Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes
    Lei Wang
    Division of Experimental Hematology, Molecular Developmental Biology Graduate Program, Children s Hospital Research Foundation, University of Cincinnati, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 104:1248-53. 2007
    ..Furthermore, Cdc42 activation is sufficient to promote a premature cellular senescence phenotype that depends on p53. These results suggest a role of Cdc42 activity in regulating mammalian genomic stability and aging-related physiology...
  60. ncbi Genetic polymorphisms and susceptibility to lung disease
    Pauline L Lee
    The Scripps Research Institute, Department of Molecular and Experimental Medicine, 10550 North Torrey Pines Road, La Jolla, 92037, USA
    J Negat Results Biomed 5:5. 2006
    ....
  61. ncbi The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats
    Yongfu Wang
    Section of Brain and Behavior, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, PR China
    Br J Pharmacol 148:147-53. 2006
    ..The present data further confirmed that enhancement of synaptic plasticity of the hippocampus might ameliorate the deficit in spatial learning and memory in aged rats...
  62. ncbi [Correlation between syndromes of posthepatitic cirrhosis and biological parameters: a report of 355 cases]
    Qin Zhang
    Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China
    Zhong Xi Yi Jie He Xue Bao 5:130-3. 2007
    ..To investigate the pathological factors of syndrome pathomechanism through studying the correlation between syndromes of posthepatitic cirrhosis and biological parameters...
  63. ncbi Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues
    Hong Bo Zhang
    Cancer Research Institute, Xiang Ya School of Medicine, Central South University, Changsha, Hunan 410078, China
    Histochem Cell Biol 127:347-54. 2007
    ..More importantly, our data showed that NPC also contained stem cells, which are most likely the cause for NPC spread, metastasis and recurrence...
  64. ncbi Effects of the dopamine D3 receptor (DRD3) gene polymorphisms on risperidone response: a pharmacogenetic study
    Jiekun Xuan
    Bio X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China
    Neuropsychopharmacology 33:305-11. 2008
    ..The current results indicate that genetic variations within the DRD3 gene may not contribute significantly to interindividual differences in the therapeutic efficacy of risperidone...
  65. ncbi Genetically encoding unnatural amino acids for cellular and neuronal studies
    Wenyuan Wang
    Jack H Skirball Center for Chemical Biology and Proteomics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Neurosci 10:1063-72. 2007
    ..This technique will stimulate and facilitate new molecular studies using tailored unnatural amino acids for cell biology and neurobiology...
  66. ncbi A comprehensive study on neurobehavior, neurotransmitters and lymphocyte subsets alteration of Chinese manganese welding workers
    Hong Yuan
    Department of Psychology, Peking University, Beijing 100871, China
    Life Sci 78:1324-8. 2006
    ..The results showed that long-term exposure to manganese in welding might have adverse effects on mood state, neurobehavior, and peripheral neurotransmitters. However, they had no effects on lymphocyte subsets parameters...
  67. ncbi Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia
    Lei Wang
    Bio X Center, Shanghai Jiao Tong University, Shanghai, China, Institute for Nutritional Science, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    J Psychopharmacol 21:837-42. 2007
    ..9-hydroxyrisperidone may not play a predominant role in elevating serum prolactin level...
  68. ncbi Attitudes toward computers: a new attitudinal dimension
    Lei Wang
    Department of Psychology, Peking University, People s Republic of China
    Cyberpsychol Behav 10:700-4. 2007
    ..A total of 2,050 participants responded to the questionnaire. Confirmatory factor analysis suggests that attitudes toward computers are composed of three dimensions: sense of benefit, sense of dependence, and sense of harm...
  69. ncbi 3D realistic head model simulation based on transcranial magnetic stimulation
    Shuo Yang
    Province Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin, China
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..The magnetic field inducted in the head bt TMS has been analysed. This three-dimensional simulation is useful for spatial localization of stimulation...
  70. ncbi Morbidity and mortality among a cohort of human immunodeficiency virus type 1-infected and uninfected pregnant women and their infants from Malawi, Zambia, and Tanzania
    David Chilongozi
    University of North Carolina Project, Lilongwe, Malawi
    Pediatr Infect Dis J 27:808-14. 2008
    ..Morbidity and mortality patterns among pregnant women and their infants (before antiretroviral therapy was widely available) determines HIV-1 diagnostic, monitoring, and care interventions...