Research Topics
Genomes and GenesSpecies | George A MaconesSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Publications
The timing of antibiotics at cesarean: a randomized controlled trialGeorge A Macones
Department of Obstetrics and Gynecology, Washington University in St Louis, 63110, USA
Am J Perinatol 29:273-6. 2012..Either preoperative antibiotic therapy or antibiotic administration after cord clamp is a reasonable clinical method for reducing the risk of postcesarean infectious morbidity...
The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelinesGeorge A Macones
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
J Obstet Gynecol Neonatal Nurs 37:510-5. 2008..A three-tier system for fetal heart rate tracing interpretation is also described. Lastly, prioritized topics for future research are provided...
Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS)George A Macones
Department of Obstetrics and Gynecology, Washington University in St Louis, School of Medicine, Campus Box 8064, 4911 Barnes Jewish Hospital Plaza, St Louis, MO 63110 1094, USA
Am J Obstet Gynecol 202:147.e1-8. 2010..The purpose of this study was to test whether treating periodontal disease (PD) in pregnancy will reduce the incidence of spontaneous preterm delivery (SPTD) at < or = 35 weeks of gestation...
The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelinesGeorge A Macones
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
Obstet Gynecol 112:661-6. 2008..A three-tier system for fetal heart rate tracing interpretation is also described. Lastly, prioritized topics for future research are provided...
Adolescent pregnancy and gestational weight gain: do the Institute of Medicine recommendations apply?Lorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO
Am J Obstet Gynecol 205:140.e1-8. 2011..The purpose of this study was to examine the Institute of Medicine (IOM) guidelines for gestational weight gain in adolescents...
The effect of fetal gender in predicting Down syndrome using long bone ultrasonographic measurementsKatherine R Goetzinger
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Prenat Diagn 30:950-5. 2010..To determine if fetal gender affects the screening efficiency of short femur and humerus lengths in the prediction of trisomy 21...
The association between prepregnancy maternal body mass index and preterm deliveryYan Zhong
Department of Obstetrics, Division of Maternal Fetal Medicine, Washington University in St Louis, St Louis, Missouri, USA
Am J Perinatol 27:293-8. 2010..3, 95% CI: 1.1, 1.6) and PPROM <34 weeks (adjusted OR = 1.4, 95% CI: 1.0, 2.0). Prepregnancy obesity increases the risk of PPROM and decreases risk of spontaneous PTD without PPROM...
Effect of gestational age at the prior cesarean delivery on maternal morbidity in subsequent VBAC attemptLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 200:276.e1-6. 2009..The purpose of this study was to estimate the effect of gestational age at the time of prior cesarean on maternal morbidity in women attempting vaginal birth after cesarean delivery (VBAC)...
Association of induction of labor and uterine rupture in women attempting vaginal birth after cesarean: a survival analysisLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, MO, USA
Am J Obstet Gynecol 206:51.e1-5. 2012..We sought to estimate the risk of uterine rupture associated with labor induction in women attempting trial of labor after cesarean (TOLAC) accounting for length of labor...
Minor trauma in pregnancy--is the evaluation unwarranted?Alison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO, USA
Am J Obstet Gynecol 198:208.e1-5. 2008..The purpose of this study was to examine the rate of and risks for abruption and adverse pregnancy outcome after minor trauma in pregnancy...
Periodontal disease and adverse pregnancy outcomes: is there an association?Sindhu K Srinivas
Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA
Am J Obstet Gynecol 200:497.e1-8. 2009..We assessed the risk of adverse pregnancy outcomes (preterm birth [PTB], preeclampsia [PRE], fetal growth restriction [FGR], or perinatal death) in women with periodontal disease (PD) compared to those without...
Safety and efficacy of vaginal birth after cesarean attempts at or beyond 40 weeks of gestationKara M Coassolo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 106:700-6. 2005..Logistic regression analyses were performed to assess the relationship between delivery beyond the EDD and VBAC failure or complication rate...
Maternal complications with vaginal birth after cesarean delivery: a multicenter studyGeorge A Macones
Department of Obstetrics and Gynecology, Leonard Davis Institute for Health Economics, University of Pennsylvania, Philadelphia, PA, USA
Am J Obstet Gynecol 193:1656-62. 2005..This study was undertaken to determine incidence and risk factors for uterine rupture in women attempting vaginal birth after cesarean delivery (VBAC) in a wide range of hospital settings...
Evaluating the thresholds of abnormal second trimester multiple marker screening tests associated with intra-uterine growth restrictionAnthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine and Ultrasound, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Am J Perinatol 23:363-7. 2006..Elevated AFP and hCG, however, were highly specific in predicting IUGR. The provided thresholds could be useful in designing policies regarding women who would benefit most from sonographic screening for IUGR...
Predicting failure of a vaginal birth attempt after cesarean deliverySindhu K Srinivas
Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 109:800-5. 2007..To identify a group of clinical factors that could be used to accurately predict failure in women attempting vaginal birth after cesarean (VBAC)...
Pregnancy loss rate after mid-trimester amniocentesis in twin pregnanciesAlison G Cahill
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 200:257.e1-6. 2009..The purpose of this study was to estimate the attributable pregnancy loss rate of mid-trimester amniocentesis in twin pregnancies...
Predicting perinatal mortality in preterm intrauterine growth restrictionChristina M Scifres
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
Am J Perinatol 26:723-8. 2009..These two variables had modest predictive value for perinatal mortality. In cases of preterm IUGR, only the presence of abnormal umbilical artery Dopplers or oligohydramnios predicts perinatal mortality...
Prevalence and likelihood ratios for aneuploidy in fetuses diagnosed prenatally with isolated congenital cardiac defectsMethodius G Tuuli
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO
Am J Obstet Gynecol 201:390.e1-5. 2009..To determine the prevalence and likelihood ratios for aneuploidy in fetuses diagnosed prenatally with isolated congenital cardiac defects...
Is vaginal birth after cesarean (VBAC) or elective repeat cesarean safer in women with a prior vaginal delivery?Alison G Cahill
Department of Obstetrics and Gynecology, Washington University, St. Louis, MO, USA
Am J Obstet Gynecol 195:1143-7. 2006..Physicians should make this more favorable benefit-risk ratio explicit when counseling this patient subpopulation on a trial of labor...
Risk of preterm delivery and growth restriction in twins discordant for structural anomaliesLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, MO, USA
Am J Obstet Gynecol 206:70.e1-5. 2012..We sought to determine whether twin gestations with an anomalous fetus are at increased risk of preterm delivery or intrauterine growth restriction (IUGR) compared to twins with 2 normal fetuses...
Single umbilical artery and its associated findingsMeiling Hua
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri, USA
Obstet Gynecol 115:930-4. 2010..To estimate whether the presence of a single umbilical artery is associated with intrauterine growth restriction (IUGR), fetal demise, or major congenital anomalies...
Leiomyomas at routine second-trimester ultrasound examination and adverse obstetric outcomesMolly J Stout
Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri 63110, USA
Obstet Gynecol 116:1056-63. 2010..To estimate the risk of adverse pregnancy outcomes associated with the presence of leiomyomas...
Vaginal birth after caesarean delivery: does maternal age affect safety and success?Sindhu K Srinivas
University of Pennsylvania Health System, Department of Obstetrics and Gynecology, Philadelphia, PA 19104, USA
Paediatr Perinat Epidemiol 21:114-20. 2007..While teenage patients do not appear to be at increased risk for VBAC-related complications, patients of advanced maternal age do show an increase in composite VBAC-related operative complication rates...
Evidence of a gene-environment interaction that predisposes to spontaneous preterm birth: a role for asymptomatic bacterial vaginosis and DNA variants in genes that control the inflammatory responseLuis M Gomez
Division of Maternal Fetal Medicine, Maternal and Child Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Obstet Gynecol 202:386.e1-6. 2010..We determined whether an environmental exposure to bacterial vaginosis (BV) modified genetic susceptibilities for spontaneous preterm delivery within genes that regulate the inflammatory response...
Does a maximum dose of oxytocin affect risk for uterine rupture in candidates for vaginal birth after cesarean delivery?Alison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO 63105, USA
Am J Obstet Gynecol 197:495.e1-5. 2007..The purpose of this study was to determine whether the maximum dose of oxytocin impacts the risk of uterine rupture in women who attempt vaginal birth after cesarean delivery (VBAC)...
Magnesium for seizure prophylaxis in patients with mild preeclampsiaAlison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri, USA
Obstet Gynecol 110:601-7. 2007..To estimate whether magnesium therapy is the optimal management for women with mild preeclampsia...
Effect of placenta previa on fetal growthLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 203:330.e1-5. 2010..To estimate the association between placenta previa and abnormal fetal growth...
Short interpregnancy interval: risk of uterine rupture and complications of vaginal birth after cesarean deliveryDavid M Stamilio
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
Obstet Gynecol 110:1075-82. 2007..To investigate whether short or long interpregnancy interval is associated with uterine rupture and other major maternal morbidities in women who attempt vaginal birth after cesarean delivery (VBAC)...
Cerebroplacental Doppler ratio and adverse perinatal outcomes in intrauterine growth restriction: evaluating the impact of using gestational age-specific reference valuesAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, 2000 Ravdin Courtyard, 3400 Spruce St, Philadelphia, PA 19104, USA
J Ultrasound Med 24:1223-8. 2005....
Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean deliveryAlison G Cahill
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 199:32.e1-5. 2008..The objective of the study was to more precisely estimate the effect of maximum oxytocin dose on uterine rupture risk in patients attempting vaginal birth after cesarean (VBAC) by considering timing and duration of therapy...
Defining nasal bone hypoplasia in second-trimester Down syndrome screening: does the use of multiples of the median improve screening efficacy?Anthony O Odibo
Division of Maternal Fetal Medicine and Clinical Research, Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO, USA
Am J Obstet Gynecol 197:361.e1-4. 2007....
Can uterine rupture in patients attempting vaginal birth after cesarean delivery be predicted?George A Macones
Department of Obstetrics and Gynecology, Washington University, St. Louis, MO, USA
Am J Obstet Gynecol 195:1148-52. 2006..67 and 0.70, respectively). CONCLUSION: Uterine rupture cannot be predicted with either individual or combinations of clinical factors. This has important clinical and medical-legal implications...
Is continuous monitoring the answer to incidentally observed fetal heart rate decelerations?Katherine M Sisco
Department of Obstetrics and Gynecology, Washington University, Saint Louis, Misouri 63110, USA
J Matern Fetal Neonatal Med 22:405-9. 2009..We examined the interventions and outcomes of pre-term patients with an incidentally identified fetal heart rate (FHR) deceleration and otherwise reassuring FHR pattern admitted for continuous FHR monitoring (FM)...
Frequent epidural dosing as a marker for impending uterine rupture in patients who attempt vaginal birth after cesarean deliveryAlison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 202:355.e1-5. 2010..The purpose of this study was to estimate the association between epidural dosing and the risk of uterine rupture in women who attempt vaginal birth after cesarean delivery (VBAC)...
Predicting placental abruption and previa in women with a previous cesarean deliveryAnthony O Odibo
Division of Maternal Fetal Medicine and Ultrasound, Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri 63110, USA
Am J Perinatol 24:299-305. 2007..In women with at least one prior cesarean delivery, the risk factors for placental previa and abruption can be identified. However, prediction models combining these risk factors were too inefficient to be useful...
Comparison of the efficiency of second-trimester nasal bone hypoplasia and increased nuchal fold in Down syndrome screeningAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine in St Louis, St Louis, MO, USA
Am J Obstet Gynecol 199:281.e1-5. 2008..The purpose of this study was to compare the efficiency of second-trimester nasal bone hypoplasia (NB) and increased nuchal fold (NF) in Down syndrome screening...
Safety and success of vaginal birth after cesarean delivery in patients with preeclampsiaSindhu K Srinivas
Department of Obstetrics and Gynecology, University of Pennsylvania Health System, 2000 Courtyard Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
Am J Perinatol 23:145-52. 2006..Patients with PRE or GH do not have increased uterine rupture rates. These findings can be used to improve mode of delivery counseling for VBAC candidate patients with preeclampsia...
Congenital uterine anomalies and adverse pregnancy outcomesMeiling Hua
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO
Am J Obstet Gynecol 205:558.e1-5. 2011..We sought to estimate whether the presence of a maternal uterine anomaly is associated with adverse pregnancy outcomes...
Should all pregnant diabetic women undergo a fetal echocardiography? A cost-effectiveness analysis comparing four screening strategiesAnthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Prenat Diagn 26:39-44. 2006..To determine if a policy of universal fetal echocardiography for all pregnant diabetic women is cost-effective as a screening tool for congenital heart defects...
Do vaginal birth after cesarean outcomes differ based on hospital setting?Emily A DeFranco
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Am J Obstet Gynecol 197:400.e1-6. 2007..The objective of the study was to test the null hypothesis that outcomes of vaginal birth after cesarean (VBAC) do not differ on the basis of the hospital setting...
The correlation in birth timing between singleton and twin gestations in the same motherEmily A DeFranco
Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0526, USA
J Matern Fetal Neonatal Med 22:106-10. 2009..To test the hypothesis that the timing of twin births is correlated to that of their singleton siblings...
Evaluating the rate and risk factors for fetal loss after chorionic villus samplingAnthony O Odibo
Division of Maternal Fetal Medicine, Ultrasound and Genetics, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, St Louis, Missouri 63110, USA
Obstet Gynecol 112:813-9. 2008..To estimate the fetal loss rate in our center and evaluate the risk factors associated with such losses after chorionic villus sampling (CVS)...
Revisiting the risk for aneuploidy in fetuses with isolated pyelectasisJeanine F Carbone
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO 63110, USA
Prenat Diagn 31:566-70. 2011..Our objective was to test the hypothesis that isolated pyelectasis is associated with aneuploidy and calculate likelihood ratios using a large ultrasound database...
Racial disparity in the success and complications of vaginal birth after cesarean deliveryAlison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri, USA
Obstet Gynecol 111:654-8. 2008..To determine if race is associated with election to attempt vaginal birth after cesarean delivery (VBAC), VBAC success, and maternal morbidities associated with VBAC...
Risk factors for bladder injury in patients with a prior hysterotomyAlison G Cahill
Department of Obstetrics and Gynecology, Washington University, St Louis, MO 63110, USA
Obstet Gynecol 112:116-20. 2008..To estimate the rate of and risk factors for bladder injury in vaginal birth after cesarean (VBAC) candidates...
Ultrasound-detected subchorionic hemorrhage and the obstetric implicationsShayna M Norman
Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri, USA
Obstet Gynecol 116:311-5. 2010..To estimate the association between the ultrasonographic diagnosis of subchorionic hemorrhage and adverse pregnancy outcomes...
Vaginal birth after cesarean (VBAC) attempt in twin pregnancies: is it safe?Alison Cahill
Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, USA
Am J Obstet Gynecol 193:1050-5. 2005..The purpose of this study was to compare the rate of vaginal birth after cesarean (VBAC) attempt, VBAC failure, and major maternal adverse outcomes in women with a previous cesarean with twin or singleton pregnancies...
Echogenic bowel on second-trimester ultrasonography: evaluating the risk of adverse pregnancy outcomeKatherine R Goetzinger
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri, USA
Obstet Gynecol 117:1341-8. 2011..To estimate if echogenic bowel diagnosed on second-trimester ultrasonography has an independent risk association with intrauterine growth restriction (IUGR) and intrauterine fetal demise...
Do race-specific definitions of short long bones improve the detection of down syndrome on second-trimester genetic sonograms?Lorie M Harper
Department of Obstetrics and Gynecology, Washington University, 660 S Euclid, Campus Box 8064, St Louis, MO 63110 USA
J Ultrasound Med 29:231-5. 2010..The purpose of this study was to determine whether the use of race-specific definitions of short femur and humerus lengths improves Down syndrome detection...
Cocaine use during pregnancy and the failure of vaginal birth after cesareanBruno F Casanova
Department of Obstetrics and Gynecology, Pennsylvania Hospital, University of Pennsylvania, 800 Spruce Street, Philadelphia, PA 19107, USA
J Reprod Med 50:663-8. 2005..To evaluate the failure rate of a trial of vaginal birth in women with singleton pregnancies and 1 prior cesarean section who reported using cocaine during the current pregnancy...
Estimation of fetal weight in fetuses with abdominal wall defects: comparison of 2 recent sonographic formulas to the Hadlock formulaSara Nicholas
Department of Obstetrics and Gynecology, Washington University School of Medicine, Campus Box 8064, 4566 Scott Ave, St Louis, MO 63110, USA
J Ultrasound Med 29:1069-74. 2010..We sought to compare the accuracy and screening efficiency for intrauterine growth restriction (IUGR) of 2 recent sonographic formulas to those of the Hadlock formula (Am J Obstet Gynecol 1985; 151:333-337) in fetuses with AWDs...
Hypnotic analgesia during first-trimester termination: Marc et alGeorge A Macones
Washington University School of Medicine, Department of Obstetrics and Gynecology, St Louis, MO, USA
Am J Obstet Gynecol 199:579-80. 2008..Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial. Am J Obstet Gynecol 2008;199:469.e1-469.e9. The full discussion appears at www.AJOG.org, page e1-e5...
Universal cervical length screening and treatment with vaginal progesterone to prevent preterm birth: a decision and economic analysisAlison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO, USA
Am J Obstet Gynecol 202:548.e1-8. 2010..The purpose of this study was to estimate which strategy is the most cost-effective for the prevention of preterm birth and associated morbidity...
Elevated serum ?-linolenic acid levels are associated with decreased chance of pregnancy after in vitro fertilizationEmily S Jungheim
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63108, USA
Fertil Steril 96:880-3. 2011..To analyze relationships between serum free fatty acid (FFA) concentrations and pregnancy...
Does the combination of fronto-maxillary facial angle and nasal bone evaluation improve the detection of Down syndrome in the second trimester?Anthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Washington University in St Louis, MO 63110, USA
Prenat Diagn 29:947-51. 2009..To determine if the combination of fronto-maxillary facial (FMF) angle and nasal bone (NB) evaluation improves the detection of Down syndrome (DS) in the second trimester...
Predicting adverse neonatal outcomes in fetuses with abdominal wall defects using prenatal risk factorsSara S Nicholas
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 201:383.e1-6. 2009..The aim of this study was to determine whether prenatal variables can predict adverse neonatal outcomes in fetuses with abdominal wall defects...
Birth outcomes of planned home births in Missouri: a population-based studyJen Jen Chang
Department of Community Health in Epidemiology, Saint Louis University School of Public Health, 3545 Lafayette Avenue, St Louis, MO 63194, USA
Am J Perinatol 28:529-36. 2011..98, 83.07) in planned home births attended by non-CNMs and by physicians/CNMs, respectively, compared with births in hospitals/birthing centers. Planned home births are associated with increased likelihood of adverse birth outcomes...
Association between pregnancy complications and small-for-gestational-age birth weight defined by customized fetal growth standard versus a population-based standardAnthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Ultrasound and Genetics, Washington University School of Medicine, St Louis, MO 63110, USA
J Matern Fetal Neonatal Med 24:411-7. 2011....
17alpha-hydroxyprogesterone caproate for the prevention of preterm delivery: A cost-effectiveness analysisAnthony O Odibo
Department of Obstetrics and Gynecology, Center for Clinical Epidemiology and Biostatistics, Internal Medicine and Health Management Systems, Washington University Medical Center in St Louis, Missouri 63110, USA
Obstet Gynecol 108:492-9. 2006..To evaluate whether the use of 17alpha-hydroxyprogesterone caproate for the prevention of recurrent preterm deliveries is cost-effective...
A cost-effectiveness analysis of prenatal screening strategies for Down syndromeAnthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 106:562-8. 2005..To evaluate which Down syndrome screening strategy is the most cost-effective...
Revisiting the fetal loss rate after second-trimester genetic amniocentesis: a single center's 16-year experienceAnthony O Odibo
Division of Maternal Fetal Medicine, Ultrasound and Genetics, Department of Obstetrics and Gynecology, Washington University in St Louis, Missouri 63110, USA
Obstet Gynecol 111:589-95. 2008..To estimate an institution's specific fetal loss rate after a second-trimester genetic amniocentesis...
Discussion: 'Predicting spontaneous preterm birth' by Esplin et alGeorge A Macones
Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, MO, USA
Am J Obstet Gynecol 204:e1-3. 2011..Proteomic identification of serum peptides predicting subsequent spontaneous preterm birth. Am J Obstet Gynecol 2011;204:391.e1-8...
Screening and treating for primary cytomegalovirus infection in pregnancy: where do we stand? A decision-analytic and economic analysisAlison G Cahill
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 201:466.e1-7. 2009..To estimate which 1 of 3 screening strategies for primary maternal cytomegalovirus infection, with intention to treat with hyperimmune globulin, is most cost-effective...
Association of first-trimester low PAPP-A levels with preterm birthKatherine R Goetzinger
Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
Prenat Diagn 30:309-13. 2010..To determine the association of, and predictive ability of, pregnancy-associated plasma protein A (PAPP-A), free beta-human chorionic gonadotrophin (beta-hCG), and nuchal translucency (NT) with preterm birth (PTB)...
Predicting success and reducing the risks when attempting vaginal birth after cesareanLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
Obstet Gynecol Surv 63:538-45. 2008..Although misoprostol use is discouraged due to its association with increased risks of uterine rupture, transcervical catheters, oxytocin, and amniotomy may be used to induce labor in women attempting VBAC...
Vaginal birth after cesarean delivery: evidence-based practiceAlison G Cahill
Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri, USA
Clin Obstet Gynecol 50:518-25. 2007..An evidence-based approach can guide practitioners and patients through the complex counseling, decision-making, and management issues when considering VBAC delivery...
Effect of hospital volume on maternal outcomes in women with prior cesarean delivery undergoing trial of laborJen Jen Chang
Division of Epidemiology, Department of Community Health, School of Public Health, Saint Louis University, St Louis, MO 63104, USA
Am J Epidemiol 167:711-8. 2008..Prior vaginal delivery was protective against adverse VBAC outcomes. The risk of an adverse VBAC outcome in low-volume hospitals was comparable to that in high-volume hospitals...
Pregnant women with the sickle cell trait are not at increased risk for developing preeclampsiaDavid M Stamilio
Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
Am J Perinatol 20:41-8. 2003..In fact, the data are more consistent with the sickle trait being protective for developing preeclampsia...
Type-specific screening for asymptomatic herpes infection in pregnancy: a decision analysisKirsten Lawrence Cleary
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, USA
BJOG 112:731-6. 2005..However, employing universal screening will likely result in a significant expenditure of medical resources because the number needed to treat to avert a single case of neonatal herpes is high...
Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletonsAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
Am J Perinatol 22:269-73. 2005..2; 95% confidence interval, 1.1 to 5.7). Perinatal morbidity was similarly significantly higher in IUGR twins. Compared with age-matched singletons, twins with IUGR have higher perinatal mortality and morbidity rates...
The effect of prematurity on vaginal birth after cesarean delivery: success and maternal morbidityJoanne N Quinones
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 105:519-24. 2005..Our hypothesis was that preterm women undergoing VBAC were more likely to be successful and have a lower rate of complications than term women undergoing VBAC...
A polymorphism in the promoter region of TNF and bacterial vaginosis: preliminary evidence of gene-environment interaction in the etiology of spontaneous preterm birthGeorge A Macones
Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women s Health, University of Pennsylvania Health System, Philadelphia, 19104 6021, USA
Am J Obstet Gynecol 190:1504-8; discussion 3A. 2004..The aim of this study was to assess if the presence of symptomatic bacterial vaginosis amplifies the risk of spontaneous preterm birth in those with a "susceptible" TNF genotype...
Embryo transfer practices in the United States: a survey of clinics registered with the Society for Assisted Reproductive TechnologyEmily S Jungheim
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63108, USA
Fertil Steril 94:1432-6. 2010..To gain a better understanding of factors influencing clinicians' embryo transfer practices...
The safety of obstetrical ultrasound: a reviewLaura E Houston
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO 63110, USA
Prenat Diagn 29:1204-12. 2009....
Staples compared with subcuticular suture for skin closure after cesarean delivery: a systematic review and meta-analysisMethodius G Tuuli
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri, USA
Obstet Gynecol 117:682-90. 2011..To estimate whether staples or subcuticular suture closure is associated with a higher risk of wound complications when used for transverse skin incisions after cesarean delivery...
Mild pyelectasis: evaluating the relationship between gestational age and renal pelvic anterior-posterior diameterAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Prenat Diagn 23:824-7. 2003..To determine the relationship between gestational age and renal pelvic anterior-posterior diameter and the feasibility of developing gestational age-specific thresholds for the diagnosis of mild pyelectasis...
Vaginal birth after cesarean for cephalopelvic disproportion: effect of birth weight difference on successLorie M Harper
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO 63110, USA
Obstet Gynecol 117:343-8. 2011..To estimate the effect of birth weight difference between the current and index pregnancy on vaginal birth after cesarean (VBAC) failure in patients whose prior cesarean was for cephalopelvic disproportion (CPD)...
Operative vaginal delivery: current trends in obstetricsKatherine R Goetzinger
Washington University, Department of Obstetrics and Gynecology, 4911 Barnes Jewish Hospital Plaza Box 8064, St Louis, MO 63110, USA
Womens Health (Lond Engl) 4:281-90. 2008....
The utility of thrombophilia testing in pregnant women with thrombosis: fact or fiction?Christina M Scifres
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Am J Obstet Gynecol 199:344.e1-7. 2008..Data regarding these issues are reviewed, controversies surrounding thrombophilia testing in this setting are discussed, and clinical recommendations are made...
Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysisMethodius G Tuuli
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
Obstet Gynecol 117:1205-12. 2011..To estimate the association between subchorionic hematoma and adverse perinatal outcomes...
First-trimester prediction of preeclampsia using metabolomic biomarkers: a discovery phase studyAnthony O Odibo
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine and Ultrasound, Washington University in St Louis, St Louis, MO 63110, USA
Prenat Diagn 31:990-4. 2011..We tested the hypothesis that first-trimester metabolic biomarkers offered a unique profile in women with preeclampsia (PE) in the second half of pregnancy, compared with controls...
Associations between free fatty acids, cumulus oocyte complex morphology and ovarian function during in vitro fertilizationEmily S Jungheim
Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri 63108, USA
Fertil Steril 95:1970-4. 2011..To determine if follicular free fatty acid (FFA) levels are associated with cumulus oocyte complex (COC) morphology...
Antenatal testing--benefits and costsChristina M Scifres
Washington University, St Louis, MO, USA
Semin Perinatol 32:318-21. 2008..Given our current limitations, we have significant difficulty accurately estimating the cost of antenatal testing; however, rough estimates of cost are made...
Diagnosing pulmonary embolism in pregnancy using computed-tomographic angiography or ventilation-perfusionAlison G Cahill
Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri, USA
Obstet Gynecol 114:124-9. 2009..To estimate the rate of nondiagnosis for patients who initially undergo computed-tomographic angiography compared with those who undergo ventilation-perfusion imaging to diagnose pulmonary embolism in pregnancy...
Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidyAnthony O Odibo
University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
J Ultrasound Med 25:437-41; quiz 443. 2006..Our objective was to evaluate the efficiency of NB hypoplasia as an independent marker for fetal aneuploidy...
Screening for aneuploidy in twins and higher-order multiples: is first-trimester nuchal translucency the solution?Anthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
Obstet Gynecol Surv 58:609-14. 2003....
What antepartum fetal test should guide the timing of delivery of the preterm growth-restricted fetus? A decision-analysisAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, University of Pennsylvania Medical Center, 3400 Spruce Street, 2000 Ravdin Courtyard, Philadelphia, PA 19104, USA
Am J Obstet Gynecol 191:1477-82. 2004..The purpose of this study was to use a decision-analytic approach to explore the best strategy for the timing of the delivery of preterm intrauterine growth-restricted fetuses...
A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African AmericansPedro E Ferrand
Center for Research on Reproduction and Women s Health, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Mol Hum Reprod 8:494-501. 2002..We conclude that there are cell host-dependent differences in MMP-9 promoter activity related to CA-repeat number and that fetal carriage of the 14 CA-repeat allele is associated with PPROM in African Americans...
The association between fetal nasal bone hypoplasia and aneuploidyAnthony O Odibo
University of Pennsylvania Medical Center, Pennsylvania Hospital, and Chestnut Hill Hospital, Philadelphia, Pennsylvania, USA
Obstet Gynecol 104:1229-33. 2004..To determine the association between fetal nasal bone hypoplasia and aneuploidy in women undergoing prenatal diagnosis...
Active management of risk in pregnancy at term in an urban population: an association between a higher induction of labor rate and a lower cesarean delivery rateJames M Nicholson
Department of Family Practice and Community Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA
Am J Obstet Gynecol 191:1516-28. 2004..A prospective randomized trial that involved active management of risk in pregnancy at term exposure is needed to further explore this association...
Abnormal multiple marker screens are associated with adverse perinatal outcomes in cases of intrauterine growth restrictionJohn G Ilagan
Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA, USA
Am J Obstet Gynecol 191:1465-9. 2004..6, 95% CI, 0.6-4.6). CONCLUSION: An elevated HCG and low uE3 were associated with APO in cases of IUGR. This information could be useful in identifying a subset of IUGR cases deserving closer surveillance...
False-positive 1-hour glucose challenge test and adverse perinatal outcomesDavid M Stamilio
Center for Clinical Epidemiology and Biostatistics and Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 103:148-56. 2004..To determine whether a false-positive 1-hour glucose challenge test (GCT) is associated with perinatal complications...
Development of a scoring system for predicting the risk of preterm birth in women receiving cervical cerclageAnthony O Odibo
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
J Perinatol 23:664-7. 2003..Our model had a high sensitivity for identifying women who may benefit from a closer surveillance...
Current concepts regarding vaginal birth after cesarean deliveryAnthony O Odibo
Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
Curr Opin Obstet Gynecol 15:479-82. 2003..Future research should focus on an evaluation of both short-term and long-term consequences of vaginal birth after cesarean delivery compared with elective repeat cesarean section...
Screening for aneuploidy in twin pregnancies: maternal age- and race-specific risk assessment between 9-14 weeksAnthony O Odibo
Division of Maternal Fetal Medicine and Genetics, University of Pennsylvania Medical Center, Philadelphia, USA
Twin Res 6:251-6. 2003....
The CARD15 2936insC mutation and TLR4 896 A>G polymorphism in African Americans and risk of preterm premature rupture of membranes (PPROM)Pedro E Ferrand
Center for Research on Reproduction and Women s Health, University of Pennsylvania, Philadelphia, PA 19104, USA
Mol Hum Reprod 8:1031-4. 2002..However, the CARD15 mutation was only detected in controls and not in PPROM cases. We conclude that the CARD15 mutation and hyporesponsive TLR4 allele do not contribute to ethnic variation in the incidence of PPROM...
Obstetric outcomes in women with two prior cesarean deliveries: is vaginal birth after cesarean delivery a viable option?George A Macones
Departments of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Obstet Gynecol 192:1223-8; discussion 1228-9. 2005....
Thromboprophylaxis after cesarean delivery: a decision analysisJoanne N Quinones
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Obstet Gynecol 106:733-40. 2005..To compare 4 strategies for managing patients after cesarean delivery...
The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trialJames M Nicholson
Department of Family Medicine and Community Health, University of Pennsylvania, Philadelphia, PA, USA
Am J Obstet Gynecol 198:511.e1-15. 2008..The purpose of this study was to compare birth outcomes that result from the active management of risk in pregnancy at term (AMOR-IPAT) to those outcomes that result from standard management...
