Research Topics
| Kevin BlackSummaryAffiliation: Washington University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
On the efficiency of stereologic volumetry as commonly implemented for three-dimensional digital imagesK J Black
Department of Psychiatry, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
Psychiatry Res 90:55-64. 1999..Implementation of the random-grid method for stereologic volumetry in three-dimensional images should in general improve sampling efficiency...- Dopamine D(1) agonist activates temporal lobe structures in primatesK J Black
Department of Psychiatry, Missouri 63110, USA
J Neurophysiol 84:549-57. 2000..We speculate that levodopa may exert its known effects on mood in humans through increased amygdala activity, mediated in part by D(1) receptors... - Template images for nonhuman primate neuroimaging: 1. BaboonK J Black
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
Neuroimage 14:736-43. 2001..The baboon structural MR and blood flow PET templates are available on the Internet (purl.org/net/kbmd/b2k) and can be used as targets for any image registration software... - Template images for nonhuman primate neuroimaging: 2. MacaqueK J Black
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
Neuroimage 14:744-8. 2001..The template images, along with copies aligned to the UCLA nemestrina brain atlas, are available on the Internet (purl.org/net/kbmd/n2k) and can be used as targets with any image registration software... - A possible substrate for dopamine-related changes in mood and behavior: prefrontal and limbic effects of a D3-preferring dopamine agonistKevin J Black
Departments of Psychiatry, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 99:17113-8. 2002.... - Rapid intravenous loading of levodopa for human research: clinical resultsKevin J Black
Department of Psychiatry and APDA Advanced Research Center for Parkinson Disease, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
J Neurosci Methods 127:19-29. 2003..D.), and produced statistically significant antiparkinsonian benefit (16% mean reduction in a standard rating of parkinsonian motor signs, P<0.0005)... - Personality disorder scores improve with effective pharmacotherapy of depressionK J Black
Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110 1093, USA
J Affect Disord 43:11-8. 1997..We hypothesized that the probability of personality disorder ('PROB') predicted by the Temperament and Character Inventory ('TCI') would decline after successful pharmacotherapy of depression... - Pathophysiology of parkinsonism due to hydrocephalusB A Racette
Department of Neurology and Neurological Surgery Neurology, Washington University School of Medicine, 660 South Euclid Ave, Box 8111, St Louis, MO 63110, USA
J Neurol Neurosurg Psychiatry 75:1617-9. 2004..Hydrocephalus associated with shunt malfunction can cause a distinct parkinsonian syndrome with greater dysfunction of projections from the medial substantia nigra to anterior striatum than in idiopathic Parkinson's disease... - Long term treatment and disease severity change brain responses to levodopa in Parkinson's diseaseT Hershey
Department of Psychiatry, Washington University School of Medicine, USA
J Neurol Neurosurg Psychiatry 74:844-51. 2003..CONCLUSIONS: It is concluded that long term levodopa treatment and disease severity affect the physiology of dopaminergic pathways, producing altered responses to levodopa in brain regions associated with motor function...
Research Grants
- Dopamine D1 Effects on Blood Flow, Metabolism, and BOLDKevin Black; Fiscal Year: 2004..abstract_text> ..
- Dopaminergic Effects on Cortical Function in Tourette'sKevin Black; Fiscal Year: 2007..The significance of this research includes its potential to define an endophenotype for future developmental or genetic studies of TS. ..
- Dopaminergic Effects on Cortical Function in Tourette'sKevin Black; Fiscal Year: 2009..The significance of this research includes its potential to define an endophenotype for future developmental or genetic studies of TS. ..