Research Topics
| G W WortmannSummaryAffiliation: Walter Reed Army Medical Center Country: USA Publications
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Detail Information
Publications
Cutaneous leishmaniasis following local trauma: a clinical pearlG W Wortmann
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC, USA
Clin Infect Dis 31:199-201. 2000..Here we report a case series and review the literature on patients who developed cutaneous leishmaniasis after local trauma, which may familiarize clinicians with this presentation...- Pulmonary manifestations of other agents: brucella, Q fever, tularemia and smallpoxGlenn Wortmann
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Respir Care Clin N Am 10:99-109. 2004..The onus is on the clinician,however, to be able to recognize the first few, unexpected cases, because early identification will be paramount in helping curb the effect of the outbreak... - Real-time polymerase chain reaction diagnosis of leishmaniasis in Panama from both fresh and frozen tissueGlenn W Wortmann
Infectious Diseases Division, Ward 63, ID Clinic, Walter Reed Army Medical Center, 6900 Georgia Avenue, NW, Washington, DC 20307 5001, USA
Trans R Soc Trop Med Hyg 98:148-51. 2004..Although the yield of PCR diagnosis was lower when testing frozen smears, the assay still outperformed existing diagnostic modalities... - Diagnosis of cutaneous leishmaniasis in Guatemala using a real-time polymerase chain reaction assay and the SmartcyclerGlenn Wortmann
Infectious Diseases Division, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Am J Trop Med Hyg 76:906-8. 2007..This study demonstrates that a RT-PCR assay can be successfully deployed to offer enhanced sensitivity for the diagnosis of CL... - Rapid diagnosis of leishmaniasis by fluorogenic polymerase chain reactionG Wortmann
Walter Reed Army Medical Center, Washington, District of Columbia, USA
Am J Trop Med Hyg 65:583-7. 2001..This assay provides a specific and rapid diagnostic modality to detect infection with Leishmania... - Rapid identification of Leishmania complexes by a real-time PCR assayGlenn Wortmann
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Am J Trop Med Hyg 73:999-1004. 2005..Real-time PCR offers rapid (within hours) identification of Leishmania to the complex level and provides a useful molecular tool to assist both epidemiologists and clinicians... - Nonhealing skin lesions in a sailor and a journalist returning from IraqEmil P Lesho
Walter Reed Army Medical Center, Washington, DC, USA
Cleve Clin J Med 72:93-4, 96, 98-9 passim. 2005..Assistance is available through the CDC and, for Department of Defense beneficiaries, certain military facilities... - Mortality associated with Acinetobacter baumannii complex bacteremia among patients with war-related traumaGrace Kang
Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Infect Control Hosp Epidemiol 31:92-4. 2010..Despite a high prevalence of multidrug-resistant strains, the 30-day mortality rate was 2%. For relatively young patients with war-related trauma, A. baumannii complex bacteremia appears to be associated with a low risk of death... - Syphilis co-infection does not affect HIV disease progressionA C Weintrob
Uniformed Services University Infectious Disease Clinical Research Program, Bethesda, MD, USA
Int J STD AIDS 21:57-9. 2010..Despite transient changes in CD4 counts and viral loads, syphilis does not appear to affect HIV disease progression... - Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of ResearchKent E Kester
Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
Vaccine 26:2191-202. 2008.... - Antimicrobial resistance surveillance in the AFHSC-GEIS networkWilliam G Meyer
Armed Forces Health Surveillance Center, 11800 Tech Rd, Silver Spring, MD 20904, USA
BMC Public Health 11:S8. 2011..This section documents the accomplishments and activities of the network through AFHSC-GEIS partners in 2009... - Incidence of bacteremia after routine tooth brushingJoshua D Hartzell
Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA
Am J Med Sci 329:178-80. 2005..Improved culture techniques suggest that these rates could be higher now. The objective of this study was to determine the current incidence of bacteremia after routine tooth brushing... - In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical CenterMichael J Zapor
Infectious Disease Service, Walter Reed Army Medical Center, 6900 Georgia Ave, Washington, DC 20307, USA
Antimicrob Agents Chemother 54:3015-7. 2010..There was no association between the arbekacin MIC and susceptibility to 16 other antibiotics or the specimen source (P = 0.7239). Synergy testing suggested an enhanced effect of arbekacin-carbapenem combinations... - A randomized, double-blind study of the efficacy of a 10- or 20-day course of sodium stibogluconate for treatment of cutaneous leishmaniasis in United States military personnelGlenn Wortmann
Division of Infectious Diseases, Walter Reed Army Medical Center, Washington, DC, USA
Clin Infect Dis 35:261-7. 2002..In this group of otherwise healthy young adults, SSG at a dosage of 20 mg/kg/day for 10 days appears to have been therapeutically equivalent and less toxic than the standard 20-day course... - Varicella zoster virus--specific immune response after treatment with sodium stibogluconate for cutaneous leishmaniasisIn Kyu Yoon
Allergy and Immunology Division, Department of Clinical Investigation, and Infectious Disease Division, Walter Reed Army Medical Center, Washington, District of Columbia 20307 5100, USA
Am J Trop Med Hyg 78:402-5. 2008..Lymphocyte proliferative responses to VZV and other antigens and mitogens did not change from baseline. The mechanism for the increased rate of VZV reactivation after treatment with sodium stibogluconate remains undefined... - Genotypic evolution of Acinetobacter baumannii strains in an outbreak associated with war traumaGlenn Wortmann
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Infect Control Hosp Epidemiol 29:553-5. 2008..Using multilocus polymerase chain reaction (PCR) and mass spectrometry to genotype isolates, we found an atypical and evolving strain distribution, distinct from those found at nonmilitary hospitals in the United States... - Emergence of multidrug resistance in bacteria and impact on antibiotic expenditure at a major army medical center caring for soldiers wounded in Iraq and AfghanistanMichael J Zapor
Department of Medicine, Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Infect Control Hosp Epidemiol 29:661-3. 2008..Moreover, antibiotic prescribing patterns during this period have changed remarkably and mirror the emergence of these organisms at our institution... - Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history studyJason F Okulicz
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
J Infect Dis 200:1714-23. 2009..042). Definitions of controllers and LTNPs describe distinct populations whose differing clinical outcomes improve with the stringency of criteria, underscoring the need for comparability between study populations... - Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical centerJoshua D Hartzell
US Army, Infectious Diseases Service, Walter Reed Army Medical Center, Bldg 2, Ward 63, 6900 Georgia Ave NW, Washington, DC 20307, USA
Clin Infect Dis 48:1724-8. 2009..The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies... - Lipsosomal amphotericin B for treatment of cutaneous leishmaniasisGlenn Wortmann
Infectious Diseases Service, Walter Reed Army Medical Center, Washington, District of Columbia 20307, USA
Am J Trop Med Hyg 83:1028-33. 2010..Although the optimum dosing regimen is undefined and the cost and toxicity may limit widespread use, liposomal amphotericin B is a viable treatment alternative for cutaneous leishmaniasis... - Cutaneous and presumed visceral leishmaniasis in a soldier deployed to AfghanistanJames P Woodrow
Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC, USA
MedGenMed 8:43. 2006..Overlap of cutaneous and visceral involvement is rare and has not been reported in our cohort. Latent Plasmodium vivax infection may have been an exacerbating cofactor. We discuss this case and present a review of the literature... - Race and mental health diagnosis are risk factors for highly active antiretroviral therapy failure in a military cohort despite equal access to careJoshua D Hartzell
Department of Internal Medicine, Walter Reed Army Medical Center, Washington DC 20307 5001, USA
J Acquir Immune Defic Syndr 44:411-6. 2007..In a US Military clinic, where beneficiaries have ready access to no-cost health care, the impact of several variables (including race) on HIV virologic suppression were examined... - Old world leishmaniasis: an emerging infection among deployed US military and civilian workersPeter J Weina
Leishmania Diagnostics Laboratory, Walter Reed Army Institute of Research, Silver Spring, MD, USA
Clin Infect Dis 39:1674-80. 2004.... - Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasisJoshua D Hartzell
Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Am J Trop Med Hyg 74:591-2. 2006..We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate... - Lack of vaccinia viremia after smallpox vaccinationJames F Cummings
Division of Infectious Diseases, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Clin Infect Dis 38:456-8. 2004..3%). Viremia with vaccinia virus after smallpox vaccination appears to be an uncommon occurrence... - A US soldier who returned from Iraq with nonhealing soresMark E Polhemus
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Clin Infect Dis 39:1008-9,1065-6. 2004 - The effect of human immunodeficiency virus on hepatitis B virus serologic status in co-infected adultsMichael L Landrum
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
PLoS ONE 5:e8687. 2010..Factors associated with serologic hepatitis B virus (HBV) outcomes in HIV-infected individuals remain incompletely understood, yet such knowledge may lead to improvements in the prevention and treatment of chronic HBV infection... - Antiretrovirals, part 1: overview, history, and focus on protease inhibitorsGary H Wynn
Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA
Psychosomatics 45:262-70. 2004..This paper reviews the mechanism of action, side effects, toxicities, and drug interactions of the protease inhibitors... - Immunologic and virologic events in early HIV infection predict subsequent rate of progressionAnuradha Ganesan
National Naval Medical Center, Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland 20892, USA
J Infect Dis 201:272-84. 2010..Because central memory T (T(CM)) cells play a critical role in the pathogenesis of simian immunodeficiency virus disease, we hypothesized that quantifying these cells in early HIV infection could provide prognostic information... - Persistence of vaccinia at the site of smallpox vaccinationJames F Cummings
Infectious Diseases Service, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
Clin Infect Dis 46:101-2. 2008..On day 21 after vaccination, 37% of volunteers were culture positive, most of whom had received vaccine for the first time. Vaccinia is detectable at least through day 21 after vaccination... - A randomized clinical trial comparing revaccination with pneumococcal conjugate vaccine to polysaccharide vaccine among HIV-infected adultsNancy F Crum-Cianflone
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda, Maryland 92134 1005, USA
J Infect Dis 202:1114-25. 2010..We determined whether revaccination with the 7-valent pneumococcal conjugate vaccine (PCV) would enhance these responses... - An AIDS patient with fever and rashEmil Lesho
Walter Reed Army Medical Center, Washington, DC, USA
Clin Infect Dis 41:75-6, 112-3. 2005 - Fever in a returned travelerEmil P Lesho
Walter Reed Army Medical Center, Washington, DC, USA
Cleve Clin J Med 72:921-7. 2005 - Infectious complications of damage control orthopedics in war traumaRupal M Mody
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
J Trauma 67:758-61. 2009..S. Army policy for war-related fractures. Data on infectious outcomes when DCO is used for war-trauma fractures are scant... - The domestic dog, a potential reservoir for Leishmania in the Peten region of GuatemalaPamela R Ryan
College of Veterinary Medicine, The University of Georgia, Athens, GA, USA
Vet Parasitol 115:1-7. 2003..These findings support the hypothesis that dogs may play an important role in the transmission of Leishmania in a region where no mammal has ever been implicated as a reservoir... - Guidelines for the prevention of infection after combat-related injuriesDuane R Hospenthal
Brooke Army Medical Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
J Trauma 64:S211-20. 2008.... - Prevention and management of infections associated with combat-related central nervous system injuriesGlenn W Wortmann
Walter Reed Army Medical Center, Washington, DC, USA
J Trauma 64:S252-6. 2008..Given these recommendations are not supported by randomized control trials or adequate cohorts studies in a military population, further efforts are needed to answer best treatment strategies... - Operation Enduring Freedom: the 48th Combat Support Hospital in AfghanistanAlan L Beitler
Department of Surgery, New Jersey Healthcare System, East Orange 07018 1095, USA
Mil Med 171:189-93. 2006..To examine the experience of the 48th Combat Support Hospital (CSH) while deployed to Afghanistan, with an emphasis on trauma care... - Increasing age at HIV seroconversion from 18 to 40 years is associated with favorable virologic and immunologic responses to HAARTAmy C Weintrob
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
J Acquir Immune Defic Syndr 49:40-7. 2008..We examined the effect of age at HIV seroconversion on response to HAART... - Visceral leishmaniasis in a soldier returning from Operation Enduring FreedomEric S Halsey
Department of Infectious Diseases, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236, USA
Mil Med 169:699-701. 2004..This case demonstrates the applicability of recently developed Leishmania polymerase chain reaction and serological assays when conventional methods of diagnosis, such as tissue microscopy and culture, fail... - Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors)Michael J Zapor
Department of Medicine, Walter Reed Army Medical Center, Uniformed Services University of the Health Sciences, F. Edward Herbert School of Medicine, Bethesda, MD, USA
Psychosomatics 45:524-35. 2004..In an overview format for primary care physicians and psychiatrists, this review presents the mechanism of action, side effects, toxicities, and drug interactions of these agents... - Med-psych drug-drug interactions update. Antiretrovirals, part III: antiretrovirals and drugs of abuseGary H Wynn
Uniformed Services University of the Health Sciences, F Edward Hebert School of Medicine, Bethesda, MD, USA
Psychosomatics 46:79-87. 2005.... - Factors associated with recovery of Acinetobacter baumannii in a combat support hospitalMatthew E Griffith
86th Combat Support Hospital, Baghdad, Iraq
Infect Control Hosp Epidemiol 29:664-6. 2008..5 to 0 cases per 1,000 patients admitted. The rate correlated with the mean census of host-nation patients in the intensive care unit, the mean census of host-nation patients on the wards, and length of stay in the intensive care unit... - Endoscopy in a deployed combat support hospital: maintaining military end-strengthAlan L Beitler
Department of Surgery, Department of Veterans Affairs New Jersey Healthcare System, East Orange, NJ 07018 1095, USA
Mil Med 171:530-3. 2006..The objective was to examine the safety and efficacy of the 48th Combat Support Hospital's use of diagnostic endoscopy in Afghanistan...