Research Topics
| Clinton K MurraySummaryAffiliation: Walter Reed Army Medical Center Country: USA Publications
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Publications
Acinetobacter skin carriage among US army soldiers deployed in IraqMatthew E Griffith
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Infect Control Hosp Epidemiol 28:720-2. 2007..This observation refutes the hypothesis that preinjury skin carriage serves as the reservoir for the Acinetobacter infections seen in US military combat casualties...
Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patientsClinton K Murray
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Arch Surg 142:639-42. 2007..To investigate whether specific values of or changes in temperature, white blood cell count, or neutrophil percentage were predictive of bloodstream infection in burn patients...
Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureusJason W Bennett
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Diagn Microbiol Infect Dis 60:437-40. 2008..The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy...
Infections complicating the care of combat casualties during operations Iraqi Freedom and Enduring FreedomClinton K Murray
Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 71:S62-73. 2011..We examine the Joint Theater Trauma Registry (JTTR) for infections and potential risk factors, such as transfusions, among Iraq and Afghanistan trauma patients...
Oral antibiotics for infections due to multidrug-resistant Gram-negative organismsJessie S Glasser
Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, Texas 78234, USA
Scand J Infect Dis 43:649-51. 2011..E. coli and K. pneumoniae susceptibilities increased by combining amoxicillin-clavulanic acid and cefdinir...
Treatment of multidrug resistant AcinetobacterClinton K Murray
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Curr Opin Infect Dis 18:502-6. 2005..This review summarizes the most recent literature pertaining to the clinical management of infections with this bacteria emphasizing in-vitro antimicrobial resistance patterns and antimicrobial efficacy in animals and humans...
History of infections associated with combat-related injuriesClinton K Murray
San Antonio Military Medical Center, Fort Sam Houston, Texas, USA
J Trauma 64:S221-31. 2008..This article reviews the history of war wound infections, with an emphasis on wound microbiology and combat casualty management during US conflicts from World War I through the end of 20th century...
Epidemiology of infections associated with combat-related injuries in Iraq and AfghanistanClinton K Murray
Brooke Army Medical Center, Fort Sam Houston, Texas, USA
J Trauma 64:S232-8. 2008..In addition, the likely sources of combat-related injuries with multidrug resistant bacteria infections are explored...
Acinetobacter infection: what was the true impact during the Vietnam conflict?Clinton K Murray
Department of Medicine, Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Fort Sam Houston, TX 78234, USA
Clin Infect Dis 43:383-4. 2006
Twenty-five year epidemiology of invasive methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered at a burn centerClinton K Murray
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Burns 35:1112-7. 2009..Continued active surveillance and aggressive infection control strategies are recommended to prevent the spread of community-acquired MRSA to this burn unit...
Occupational exposure to blood and other bodily fluids at a military hospital in IraqClinton K Murray
Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 66:S62-8. 2009....
Infections in combat casualties during Operations Iraqi and Enduring FreedomClinton K Murray
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 66:S138-44. 2009..The Joint Theater Trauma Registry (JTTR) has been established to collect injury specific medical data from casualties in Iraq and Afghanistan...
The remote diagnosis of malaria using telemedicine or e-mailed imagesClinton K Murray
Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA
Mil Med 171:1167-71. 2006..Correct speciation ranged from 45% to 83% across various transmission methods and Bw. The use of telemedicine and e-mail technology shows promise for the remote diagnosis of malaria...
Incidence of systemic fungal infection and related mortality following severe burnsClinton K Murray
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Burns 34:1108-12. 2008....
Infectious disease complications of combat-related injuriesClinton K Murray
Brooke Army Medical Center, Fort Sam Houston, TX, USA
Crit Care Med 36:S358-64. 2008..These strategies allow patients to survive near-catastrophic injuries, placing a greater emphasis on the medical infrastructure to mitigate short- and long-term complications associated with these injuries...
Acinetobacter infection in the ICUClinton K Murray
Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Crit Care Clin 24:237-48, vii. 2008..Infection control and antibiotic control measures might have the greatest impact on these bacteria. Continued efforts are needed to develop new antimicrobial agents against this pathogen and assess the ideal currently available agents...
Prevention and management of infections associated with combat-related extremity injuriesClinton K Murray
Brooke Army Medical Center, Fort Sam Houston, Texas, USA
J Trauma 64:S239-51. 2008..Most of the recommendations are not supported by randomized controlled trials or adequate cohorts studies in a military population and further efforts are needed to answer best treatment strategies...
Medical problems of detainees after the conclusion of major ground combat during Operation Iraqi FreedomClinton K Murray
1st Brigade Combat Team, 1st Infantry Division, APO AE 09394
Mil Med 170:501-4. 2005..Medical problems not traditionally dealt with in a combat theater, including management of transplant recipients, patients with cardiac valve replacement, and cancer patient, were also seen...
An approach to prevention of infectious diseases during military deploymentsClinton K Murray
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Clin Infect Dis 44:424-30. 2007..Many of the components of military deployment medicine are applicable to civilian disaster relief and humanitarian missions...
Use of patient-specific Leptospira isolates in the diagnosis of leptospirosis employing microscopic agglutination testing (MAT)Clinton K Murray
San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Trans R Soc Trop Med Hyg 105:209-13. 2011..However, the serovar with the highest titers did not match the cultured serovar. Region-specific MATs did not appear to be reliable in detection of infection or in identifying the infecting serovar...
Rapid diagnostic testing for malariaClinton K Murray
Infectious Diseases Service, Brooke Army Medical Center, San Antonio, TX 78234 6200, USA
Trop Med Int Health 8:876-83. 2003....
Methicillin-resistant Staphylococcus aureus in wound cultures recovered from a combat support hospital in IraqClinton K Murray
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 69:S102-8. 2010..aureus (CA-MRSA) strains seem to produce severe disease but retain susceptibility to many oral antimicrobials. This study characterizes 84 MRSA isolates recovered from wound cultures at a combat support hospital in Iraq...
Update on rapid diagnostic testing for malariaClinton K Murray
Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Clin Microbiol Rev 21:97-110. 2008..This review highlights RDTs, including challenges in assessing their performance, internationally available RDTs, their effectiveness in various health care settings, and the selection of RDTs for different health care systems...
Short report: Treatment failure in Hansen's diseaseClinton K Murray
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234 6200, USA
Am J Trop Med Hyg 68:233-4. 2003..The accurate diagnosis of relapse of this disease is essential not only in the individual patient but also for prospective treatment trials to establish best practices...
Susceptibility of Leptospira serovars to antimalarial agentsClinton K Murray
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Am J Trop Med Hyg 71:685-6. 2004..The only agents identified with the potential to treat both infections other than doxycycline (MIC(90) = 1.56 microg/mL) were azithromycin (MIC(90) = 0.002 microg/mL) and clindamycin (MIC(90) = 0.2 microg/mL)...
Infections in burnsClinton K Murray
Brooke Army Medical Center, USA
J Trauma 62:S73. 2007
Bacteriology of war wounds at the time of injuryClinton K Murray
Department of Medicine, Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Mil Med 171:826-9. 2006..These data suggest that the use of broad-spectrum antibiotics with efficacy against more resistant, Gram-negative bacteria, such as Pseudomonas aeruginosa and Acinetobacter spp., is unnecessary in early wound management...
Bacteria recovered from patients admitted to a deployed U.S. military hospital in Baghdad, IraqHeather C Yun
Infectious Diseases Department, Wilford Hall US Air Force Medical Center, San Antonio, TX 78236, USA
Mil Med 171:821-5. 2006..These differences in prevalence were all statistically significant, when compared in chi2 analyses (p < 0.05). Antimicrobial susceptibility testing demonstrated broad resistance among the Gram-negative and Gram-positive bacteria...
Infectious complications of noncombat trauma patients provided care at a military trauma centerHeather C Yun
San Antonio Military Medical Center, Fort Sam Houston, TX, USA
Mil Med 175:317-23. 2010..In burned patients, infection was associated with total body surface area burned and preexisting conditions (p < 0.01). Enhanced infection control in targeted trauma populations may improve outcomes...
Changes in the incidences of multidrug-resistant and extensively drug-resistant organisms isolated in a military medical centerEdward F Keen
San Antonio Military Medical Center, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
Infect Control Hosp Epidemiol 31:728-32. 2010..Multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa have emerged as the causes of nosocomial infections in critically ill patients...
Antimicrobial susceptibilities of geographically diverse clinical human isolates of LeptospiraRoseanne A Ressner
Brooke Army Medical Center, Fort Sam Houston, Texas, USA
Antimicrob Agents Chemother 52:2750-4. 2008..There appears to be possible variability in susceptibility to some antimicrobial agents among strains, suggesting that more extensive testing to look for geographic variability should be pursued...
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster modelMatthew E Griffith
Infectious Disease Service, MCHE MDI, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 51:2615-7. 2007..Each agent produced a statistically significant survival advantage compared to no treatment and demonstrated survival similar to that seen with doxycycline therapy...
Contribution of bacterial and viral infections to attributable mortality in patients with severe burns: an autopsy seriesLaurie C D'Avignon
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Burns 36:773-9. 2010..aureus remain the most common cause of bacteria related mortality early in the hospital course. Viral infections are also associated with mortality and numbers have remained stable when compared to data from prior years...
Association of bacterial colonization at the time of presentation to a combat support hospital in a combat zone with subsequent 30-day colonization or infectionRobert L Kaspar
Department of Medicine, Darnall Army Medical Center, Fort Hood, TX, USA
Mil Med 174:899-903. 2009..Carefully obtained screening cultures immediately after injury combined with look-back monitoring supports the role of nosocomial transmission. Consistent infection control strategies are needed for the entire MHS...
In vitro and in vivo activity of first generation cephalosporins against leptospiraBrande M Harris
Department of Medicine, Wilford Hall Medical Center, Lackland Air Force Base, Texas Departments of Medicine and Clinical Investigation, Brooke Army Medical Center, Fort Sam Houston, Texas Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland Department of Medicine, Elgin Hospital, Elgin Air Force Base, Florida
Am J Trop Med Hyg 85:905-8. 2011..01), and none of the therapies, regardless of dose, was statistically significantly different than doxycycline. These results support a potential role for first generation cephalosporins as alternative therapies for leptospirosis...
Multidrug-resistant bacterial colonization of combat-injured personnel at admission to medical centers after evacuation from Afghanistan and IraqDuane R Hospenthal
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 71:S52-7. 2011..Admission screening for MDRO colonization has been established to monitor this problem and effectiveness of responses to it...
Outcomes of bacteremia in burn patients involved in combat operations overseasRoseanne A Ressner
Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
J Am Coll Surg 206:439-44. 2008..It is currently unclear if bacteremia with these multidrug-resistant organisms in OIF/OEF burn casualties is associated with increased mortality...
Efficacy of caspofungin and posaconazole in a murine model of disseminated Exophiala infectionRobert G Rivard
Department of Medicine, Brooke Army Medical Center Fort Sam Houston, Texas 78234, USA
Med Mycol 45:685-9. 2007..Amphotericin B and posaconazole reduced fungal burden. Posaconazole and caspofungin appear to have potential for use in treatment of this rare infection...
Aminoglycoside resistance and susceptibility testing errors in Acinetobacter baumannii-calcoaceticus complexKevin S Akers
Infectious Disease Service, San Antonio Military Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, Texas 78234 6200, USA
J Clin Microbiol 48:1132-8. 2010..Determination of the relative contribution of multiple concurrent resistance mechanisms may improve our understanding of aminoglycoside resistance in the Acinetobacter baumannii-calcoaceticus complex...
Guidelines for the prevention of infections associated with combat-related injuries: 2011 update: endorsed by the Infectious Diseases Society of America and the Surgical Infection SocietyDuane R Hospenthal
Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 71:S210-34. 2011....
Detection of simulated candidemia by the BACTEC 9240 system with plus aerobic/F and anaerobic/F blood culture bottlesLynn L Horvath
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Clin Microbiol 41:4714-7. 2003..glabrata is clinically significant. Given the high rate of false negatives, terminal subcultures may be helpful in certain situations...
Carbapenem susceptibility testing errors using three automated systems, disk diffusion, Etest, and broth microdilution and carbapenem resistance genes in isolates of Acinetobacter baumannii-calcoaceticus complexAna Elizabeth Markelz
LTC, MC, USA, Infectious Disease Service, Brooke Army Medical Center, 3551 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 55:4707-11. 2011..8 and 30.8%. International variability in carbapenem breakpoints and the absence of CLSI breakpoints for doripenem present a challenge in susceptibility testing...
Presumptive identification of Candida species other than C. albicans, C. krusei, and C. tropicalis with the chromogenic medium CHROMagar CandidaDuane R Hospenthal
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
Ann Clin Microbiol Antimicrob 5:1. 2006..CaC is a differential chromogenic medium designed to identify C. albicans, C. krusei, and C. tropicalis based on colony color and morphology. Some reports have proposed that CaC can also reliably identify C. dubliniensis and C. glabrata...
Recovery of multidrug-resistant bacteria from combat personnel evacuated from Iraq and Afghanistan at a single military treatment facilityClinton K Murray
San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 27834, USA
Mil Med 174:598-604. 2009..Novel techniques are needed to control the impact of MDR bacteria in medical facilities...
Prevention of infections associated with combat-related extremity injuriesClinton K Murray
Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 71:S235-57. 2011..This evidence-based medicine review was produced to support the Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update contained in this supplement of Journal of Trauma...
Clostridium difficile infections in patients with severe burnsScott J Crabtree
San Antonio Military Medical Center, Fort Sam Houston, TX, USA
Burns 37:42-8. 2011....
Prevalence of multidrug-resistant organisms recovered at a military burn centerEdward F Keen
San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Burns 36:819-25. 2010....
Tetracycline susceptibility testing and resistance genes in isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus complex from a U.S. military hospitalKevin S Akers
San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 53:2693-5. 2009..Susceptibilities varied significantly with the testing method. The acquired tetracycline resistance genes tetA, tetB, and tetA(39) were present in the isolates...
Guidelines for the prevention of infection after combat-related injuriesDuane R Hospenthal
Brooke Army Medical Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
J Trauma 64:S211-20. 2008....
Central nervous system infections in patients with severe burnsTatjana P Calvano
Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
Burns 36:688-91. 2010..4-2% of all patients hospitalized with head trauma. CNS infection incidence in burn patients is unknown and this study sets out to identify the incidence and risk factors associated with CNS infections...
Efficacy of macrolides and telithromycin against leptospirosis in a hamster modelJames E Moon
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
Antimicrob Agents Chemother 50:1989-92. 2006..We conclude that all agents tested have demonstrated in vivo efficacy in treating acute leptospirosis. These results provide support for further evaluation of macrolide and ketolide antimicrobial agents in human trials...
Description of Streptococcus pneumoniae infections in burn patientsJessie S Glasser
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Burns 36:528-32. 2010..Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections, the incidence and risk factors for pneumococcal infections in burn patients is unclear...
Causes of mortality by autopsy findings of combat casualties and civilian patients admitted to a burn unitRuben Gomez
Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
J Am Coll Surg 208:348-54. 2009..Approximately 5% of combat-related injuries include burns. Previous studies have shown similar mortality rates between military and civilian burn casualties; but causes of death were not detailed...
Effect of timing and duration of azithromycin therapy of leptospirosis in a hamster modelJames E Moon
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
J Antimicrob Chemother 59:148-51. 2007..In this study, the utility of short courses of azithromycin in treating or preventing leptospirosis was investigated in a lethal hamster model...
Activity of topical antimicrobial agents against multidrug-resistant bacteria recovered from burn patientsJessie S Glasser
San Antonio Military Medical Center, Fort Sam Houston, TX, USA
Burns 36:1172-84. 2010..We compared two methods of determining topical antimicrobial susceptibilities...
Prevention of infections associated with combat-related central nervous system injuriesMichael A Forgione
Infectious Disease Service, Keesler Medical Center, Keesler Air Force Base, Mississippi 39534, USA
J Trauma 71:S258-63. 2011..This evidence-based medicine review was produced to support the Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update contained in this supplement of Journal of Trauma...
Fungal wound infection (not colonization) is independently associated with mortality in burn patientsEdward E Horvath
U S Army Institute of Surgical Research, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Ann Surg 245:978-85. 2007..To analyze the occurrence of fungal wound infection (FWI) after thermal injury and its relationship to mortality...
Infection prevention and control in deployed military medical treatment facilitiesDuane R Hospenthal
Infectious Disease Service, San Antonio Military Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
J Trauma 71:S290-8. 2011..This review was produced to support the Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update contained in this supplement of Journal of Trauma...
Susceptibility of acinetobacter strains isolated from deployed U.S. military personnelJoshua S Hawley
Infectious Disease Service MCHE MDI 7E, Brooke Army Medical Center, 3851 Roger Brooke Dr, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 51:376-8. 2007..S. soldiers deployed overseas) to 13 antimicrobial agents were determined by broth microdilution. The most active antimicrobial agents (> or =95% of isolates susceptible) were colistin, polymyxin B, and minocycline...
Endocarditis in burn patients: clinical and diagnostic considerationsJason A Regules
Brooke Army Medical Center, Fort Sam Houston, TX, USA
Burns 34:610-6. 2008..Further analysis of the clinical presentation and diagnosis may aid in the earlier recognition and decreased mortality of endocarditis in burned patients...
Impact of Acinetobacter infection on the mortality of burn patientsMichael C Albrecht
US Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA
J Am Coll Surg 203:546-50. 2006..CONCLUSIONS: Multidrug-resistant Acb is a common cause of nosocomial infection in the burn patient population. Despite this, it does not independently affect mortality...
Incidence and bacteriology of burn infections at a military burn centerEdward F Keen
San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Burns 36:461-8. 2010....
Correlation of culture with histopathology in fungal burn wound colonization and infectionChristina M Schofield
Wilford Hall USAF Medical Center, Lackland AFB, TX, USA
Burns 33:341-6. 2007..Future burn wound management must seek to identify fungal pathogens to species...
Prevention and treatment of infected foot and ankle wounds sustained in the combat environmentBrendan D Masini
Brooke Army Medical Center BAMC, Fort Sam Houston, TX 78234, USA
Foot Ankle Clin 15:91-112. 2010....
Broth microdilution susceptibility testing for Leptospira sppClinton K Murray
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
Antimicrob Agents Chemother 48:1548-52. 2004..The macrodilution and microdilution techniques produced similar results, with microdilution allowing a faster, more streamlined method of producing MIC results...
Spectrum of care provided at an echelon II Medical Unit during Operation Iraqi FreedomClinton K Murray
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Mil Med 170:516-20. 2005..Determining the types of casualties seen at forward echelons of medical care during different phases of conflict can aid medical planning and help predict the type of medical resources required...
Once-daily amikacin dosing in burn patients treated with continuous venovenous hemofiltrationKevin S Akers
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 55:4639-42. 2011..The low pharmacodynamic target attainment appears to be primarily due to higher amikacin MICs rather than more rapid clearance of amikacin related to CVVH therapy...
Earlier debridement and antibiotic administration decrease infectionKate V Brown
US Army Institute of Surgical Research, 3400 Rawley E Chambers, Suite B, Fort Sam Houston, TX 78234, USA
J Surg Orthop Adv 19:18-22. 2010..It was concluded that early debridement in combination with local delivery of antibiotics of contaminated defects may reduce infections...
Executive summary: Guidelines for the prevention of infections associated with combat-related injuries: 2011 update: endorsed by the Infectious Diseases Society of America and the Surgical Infection SocietyDuane R Hospenthal
San Antonio Military Medical Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
J Trauma 71:S202-9. 2011....
Direct isolation of Candida spp. from blood cultures on the chromogenic medium CHROMagar CandidaLynn L Horvath
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Clin Microbiol 41:2629-32. 2003..Direct isolation could allow mycology laboratories to more rapidly identify Candida spp., enable clinicians to more quickly make antifungal agent selections, and potentially decrease patient morbidity and mortality...
Viability of Leptospira in BacT/ALERT MB mediaMatthew E Griffith
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Diagn Microbiol Infect Dis 54:263-6. 2006..Viable leptospires were detected in MB bottles up to day 14. FA and SN were performed in accordance with prior data. We conclude that MB and enriched MB bottles of the BacT/ALERT blood culture system can support viable leptospires...
In vitro susceptibilities of seven Leptospira species to traditional and newer antibioticsDuane R Hospenthal
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
Antimicrob Agents Chemother 47:2646-8. 2003..With the exception of chloramphenicol, all tested agents were at least as potent as penicillin and doxycycline, with the macrolide and ketolide drugs producing the lowest MICs (and minimal bactericidal concentrations)...
Central retinal vein occlusion in an Army Ranger with glucose-6-phosphate dehydrogenase deficiencyRuss S Kotwal
75th Ranger Regiment, Fort Benning, GA 31905, USA
J Spec Oper Med 9:59-63. 2009..This case underscores the continued need for routine G6PD screening and avoidance of known triggers in G6PD-deficient individuals...
Direct comparison of the BACTEC 9240 and BacT/ALERT 3D automated blood culture systems for candida growth detectionLynn L Horvath
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Clin Microbiol 42:115-8. 2004..However, when only standard aerobic and anaerobic media were used, the BacT performed better than the Bactec in overall growth detection, time to growth detection, and number of false-negatives...
Effect of various concentrations of antibiotics on osteogenic cell viability and activityChristopher R Rathbone
United States Army Institute of Surgical Research, 3400 Rawley E Chambers, Fort Sam Houston, Texas 78234, USA
J Orthop Res 29:1070-4. 2011..This comprehensive evaluation of numerous antibiotics' effects on osteoblast viability and activity will enable clinicians and researchers to choose the optimal antibiotic for treatment of infection and maintenance of healthy host bone...
Pneumonia in military trainees: a comparison study based on adenovirus serotype 14 infectionTodd J Vento
Infectious Diseases Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
J Infect Dis 203:1388-95. 2011..This study was conducted to determine whether Ad-14 is associated with clinical outcomes in otherwise healthy patients with pneumonia...
Preface: Guidelines for the prevention of infections associated with combat-related injuries: 2011 updateDuane R Hospenthal
Infectious Disease Service MCHE MDI, San Antonio Military Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
J Trauma 71:S197-201. 2011....
Antimicrobial resistance surveillance in the AFHSC-GEIS networkWilliam G Meyer
Armed Forces Health Surveillance Center, 11800 Tech Rd, Silver Spring, MD 20904, USA
BMC Public Health 11:S8. 2011..This section documents the accomplishments and activities of the network through AFHSC-GEIS partners in 2009...
The role of antifungal susceptibility testing in the therapy of candidiasisDuane R Hospenthal
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234 6200, USA
Diagn Microbiol Infect Dis 48:153-60. 2004....
Temporary external fixation is safe in a combat environmentDaniel R Possley
United States Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
J Trauma 69:S135-9. 2010..We hypothesize that external fixation is a safe and effective initial stabilization procedure for combat-related open fractures...
Response to infection control challenges in the deployed setting: Operations Iraqi and Enduring FreedomDuane R Hospenthal
Infectious Disease Service, San Antonio Military Medical Center, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 69:S94-101. 2010..In response, efforts to emphasize IC basics, improve expertise, and better track MDRO colonization were pursued...
Central nervous system toxicity associated with liposomal amphotericin B therapy for cutaneous leishmaniasisJessie S Glasser
US Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Am J Trop Med Hyg 84:566-8. 2011..This is a potential side effect of liposomal amphotericin B that can be observed in otherwise healthy patients...
Determination of susceptibilities of 26 Leptospira sp. serovars to 24 antimicrobial agents by a broth microdilution techniqueClinton K Murray
Infectious Disease (MCHE-MDI, Brooke Army Medical Center, 3851 Roger Brooke Dr, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 48:4002-5. 2004..01 microg/ml. The MIC(90)s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were >/=3.13 microg/ml. Many antimicrobials have excellent in vitro activity against Leptospira...
Hospital-acquired device-associated infections at a deployed military hospital in IraqErica N Johnson
Infectious Disease Service, Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, USA
J Trauma 66:S157-63. 2009..We describe the rates of utilization and device-associated infections at the Air Force Theater Hospital (AFTH) in Iraq...
Colistin heteroresistance in acinetobacter and its association with previous colistin therapyJoshua S Hawley
Department of Medicine, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
Antimicrob Agents Chemother 52:351-2. 2008..The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin...
Osteomyelitis in military personnel wounded in Iraq and AfghanistanHeather C Yun
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
J Trauma 64:S163-8; discussion S168. 2008..We describe demographics and microbiology of OIF/OEF casualties with primary and recurrent osteomyelitis...
Acinetobacter skin colonization of US Army SoldiersMatthew E Griffith
Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Infect Control Hosp Epidemiol 27:659-61. 2006..To evaluate whether skin colonization with Acinetobacter calcoaceticus-baumannii complex exists in a population of healthy, nondeployed US Army soldiers and, if present, how it might relate to the infections seen in current war casualties...
Fusarium proliferatum superficial suppurative thrombophlebitisClinton K Murray
Department of Medicine, Infectious Diseases Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234 6200, USA
Mil Med 168:426-7. 2003..We report a case of Fusarium proliferatum superficial suppurative thrombophlebitis in an immunocompetent patient with no evidence of systemic infection and who responded to venotomy alone...
Persistence of pigment production by yeast isolates grown on CHROMagar Candida mediumDuane R Hospenthal
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
J Clin Microbiol 40:4768-70. 2002..Candida tropicalis produced colonies similar to those of rare Cryptococcus and Trichosporon species, and mixed cultures were often difficult to identify as such...
Analysis of anaerobic blood cultures in burned patientsJason A Regules
Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Burns 33:561-4. 2007..However anaerobic blood cultures systems are also able to detect facultative and obligate aerobic bacteria; therefore, the deletion of the anaerobic culture medium may have deleterious clinical impact...
Devices for rapid diagnosis of Malaria: evaluation of prototype assays that detect Plasmodium falciparum histidine-rich protein 2 and a Plasmodium vivax-specific antigenJ Russ Forney
United States Military Academy, West Point, New York, USA
J Clin Microbiol 41:2358-66. 2003..vivax were 0.8907 and 0.8522, respectively. These findings indicate that assays for rapid diagnosis have the potential to enhance diagnostic capabilities in those instances in which skilled microscopy is not readily available...
Infection rates in U.S. military personnel using vacuum-assisted closureSteven J Lalliss
Plast Reconstr Surg 120:574-5; author reply 575-6. 2007
Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complexJoshua S Hawley
Antimicrob Agents Chemother 51:4529-30. 2007
Multidrug-resistant organisms in military wounds from Iraq and AfghanistanJason H Calhoun
Department of Orthopaedic Surgery, University of Missouri, MC213, DC053 00, One Hospital Drive, Columbia, MO 65212, USA
Clin Orthop Relat Res 466:1356-62. 2008..More research is required to give military physicians the tools they require to reduce the infection rate and defeat multidrug-resistant organisms...
Development of a deployment course for graduating military internal medicine residentsClinton K Murray
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Mil Med 171:933-6. 2006..Residents uniformly accepted the course with measurable increase in their fund of knowledge at the completion of the course...
Ventilator associated pneumonia in a military deployed setting: the impact of an aggressive infection control programMichael L Landrum
From the Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USA
J Trauma 64:S123-7; discussion S127-8. 2008..We describe the rates of ventilator-associated pneumonia (VAP) before and after the implementation of aggressive infection control measures at the Air Force Theater Hospital in Iraq...
Orthopaedic war injuries: from combat casualty care to definitive treatment: a current review of clinical advances, basic science, and research opportunitiesDana C Covey
Department of Orthopaedic Surgery, Naval Medical Center, San Diego, California, USA
Instr Course Lect 57:65-86. 2008..Research on the treatment of these often devastating wounds also will have broad applicability to trauma resulting from acts of terrorism or from natural disasters...
Causes of fever in adults on the Thai-Myanmar borderRuth D Ellis
Armed Forces Research Institute for Medical Sciences (AFRIMS, Bangkok, Thailand
Am J Trop Med Hyg 74:108-13. 2006..Apparent dual diagnoses were common, particularly for malaria and leptospirosis. Findings have been used to modify treatment of unspecified febrile illness in the area...
Bullis fever: a vanished infection of unknown etiologyClinton K Murray
Department of Medicine, Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, TX 78216, USA
Mil Med 169:863-5. 2004..However, given Camp Bullis' status as an active medical training site, awareness of and surveillance for the disease should continue...
Acinetobacter nares colonization of healthy US soldiersMatthew E Griffith
Infect Control Hosp Epidemiol 27:787-8. 2006
Frequency of vaccinia virus isolation on semipermeable versus nonocclusive dressings covering smallpox vaccination sites in hospital personnelMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, and US Army Medical Research Institute of Infectious Diseases, MCMR-UIM-O (Hepburn, 1425 Porter Street, Ft. Detrick, MD 21702-5011, USA
Am J Infect Control 32:126-30. 2004..Virus was present, but only rarely, on the dressing surface in the absence of purulent exudate under the semipermeable dressings...
