Research Topics
| Matthew J HepburnSummaryAffiliation: Walter Reed Army Medical Center Country: USA Publications
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Detail Information
Publications
Comparison of short-course (5 days) and standard (10 days) treatment for uncomplicated cellulitisMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Tex, USA
Arch Intern Med 164:1669-74. 2004..Cellulitis is a condition routinely encountered in the primary care setting. No previous study has compared a short (5 days) vs standard (10 days) course of therapy of the same antibiotic in patients with uncomplicated cellulitis...
Tularemia: current diagnosis and treatment optionsMatthew J Hepburn
United States Army, Defence Science and Technology Laboratory, Porton Down, UK
Expert Rev Anti Infect Ther 6:231-40. 2008..We conclude the article with suggestions regarding potential areas for future research...
Pathogenesis and sepsis caused by organisms potentially utilized as biologic weapons: opportunities for targeted interventionMatthew J Hepburn
Defence Science and Technology Laboratories, Porton Down, Wiltshire, UK
Curr Drug Targets 8:519-32. 2007..For other organisms, further elucidation of the mechanisms of pathogenesis and septic shock is needed to direct therapeutic exploration...
Live vaccine strain Francisella tularensis is detectable at the inoculation site but not in blood after vaccination against tularemiaMatthew J Hepburn
Division of Medicine, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
Clin Infect Dis 43:711-6. 2006..LVS vaccination of laboratory workers provided the opportunity to compare culture with polymerase chain reaction (PCR) for the detection of F. tularensis in human clinical samples...
The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with hepatitis C in a clinical setting: a retrospective observational studyMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, Fort Sam, Houston, Texas, USA
BMC Gastroenterol 5:14. 2005..Our hypothesis was ultrasonography would perform poorly for the detection of steatosis outside of the context of a controlled study, primarily due to false-positive results caused by hepatic fibrosis and inflammation...
Seroprevalence of hepatitis C and associated risk factors among an urban population in HaitiMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, San Antonio, Texas, USA
BMC Gastroenterol 4:31. 2004..The purpose of this investigation was to determine the seroprevalence of hepatitis C and associated risk factors in an urban population in Haiti...
Differences in treatment outcome for hepatitis C among ethnic groupsMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, Fort Sam, Houston, Texas, USA
Am J Med 117:163-8. 2004..Studies of interferon-based therapies for hepatitis C virus (HCV)-infected patients have documented variable response rates according to ethnicity. However, these studies enrolled low numbers of ethnic minorities...
Low serum vitamin B12 levels in an outpatient HIV-infected populationMatthew J Hepburn
Brooke Army Medical Center, MCHE MDI 4W, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234 6200, USA
Int J STD AIDS 15:127-33. 2004..04). In conclusion, low serum B12 levels occur commonly among HIV-infected patients, even at early stages without overt symptoms of B12 deficiency. Antiretroviral therapy may increase serum B12 levels...
Septic arthritis caused by Granulicatella adiacens: diagnosis by inoculation of synovial fluid into blood culture bottlesMatthew J Hepburn
Brooke Army Medical Center, MCHE MDI 4 W, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234 6200, USA
Rheumatol Int 23:255-7. 2003..Granulicatella should be considered in cases of septic arthritis with initially negative synovial fluid cultures. Inoculation of blood cultures bottles with synovial fluid may increase the diagnostic yield for these species...
A pilot study of interleukin-11 in subjects with chronic hepatitis C and advanced liver disease nonresponsive to antiviral therapyEric J Lawitz
Gastroenterology Service, Brooke Army Medical Center, San Antonio, Texas, USA
Am J Gastroenterol 99:2359-64. 2004..Larger clinical trials are warranted to further evaluate the long-term antiinflammatory and antifibrotic effects of rhIL-11...
Frequency of vaccinia virus isolation on semipermeable versus nonocclusive dressings covering smallpox vaccination sites in hospital personnelMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, and US Army Medical Research Institute of Infectious Diseases, MCMR-UIM-O (Hepburn, 1425 Porter Street, Ft. Detrick, MD 21702-5011, USA
Am J Infect Control 32:126-30. 2004..Virus was present, but only rarely, on the dressing surface in the absence of purulent exudate under the semipermeable dressings...
Outcomes of community-acquired, methicillin-resistant Staphylococcus aureus, soft tissue infections treated with antibiotics other than vancomycinEdward V Barnes
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA
Mil Med 171:504-7. 2006..cMRSA skin and soft tissue infections can be successfully treated with orally administered antibiotics to which the organism has demonstrable in vitro susceptibility...
Pertussis in a military and military beneficiary population: case series and review of the literatureFrank L Christopher
Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam, Houston, TX 78234, USA
Mil Med 167:215-8. 2002..The medical management of active duty soldiers and their dependents (both pediatric and adult) with this largely underappreciated infection and their close contacts is presented...
Minocycline-induced black bone diseaseMatthew J Hepburn
Department of Medicine, Brooke Army Medical Center, Ft Sam Houston, TX, USA
Orthopedics 28:501-2. 2005
Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccinationClaudette L Fuller
United States Army Medical Research Institute of Infectious Diseases, Bacteriology Division, 1425 Porter Street, Frederick, MD 21702 5011, USA
Mol Immunol 44:3173-84. 2007..tularensis. Additionally, we obtained valuable information that should prove useful in evaluation of vaccine lots as well as efficacy testing of new anti-F. tularensis vaccines...
Dominance of human innate immune responses in primary Francisella tularensis live vaccine strain vaccinationClaudette L Fuller
J Allergy Clin Immunol 117:1186-8. 2006
Alternative diagnoses that often mimic cellulitisMatthew J Hepburn
Am Fam Physician 67:2471. 2003
