Research Topics
Species | John R StehleSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Detail Information
Publications
Novel innate cancer killing activity in humansMichael J Blanks
Molecular Genetics and Genomics Program, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina, 27157, USA
Cancer Cell Int 11:26. 2011..abstract:..
Impact of sex, MHC, and age of recipients on the therapeutic effect of transferred leukocytes from cancer-resistant SR/CR miceJohn R Stehle
Department of Pathology, Wake Forest University School of Medicine Winston Salem, North Carolina 27157, USA
BMC Cancer 9:328. 2009..In the current studies, we investigated factors that may impact the efficacy and functionality of SR/CR donor leukocytes in recipients...
Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirementsAnne M Sanders
Department of Pathology, Wake Forest University School of Medicine Winston Salem, North Carolina, USA
BMC Cancer 10:121. 2010..This was tested by cross breeding SR/CR mice into the individual genetic knockout backgrounds of perforin (Prf-/-), superoxide (Cybb-/), or inducible nitric oxide (Nos2-/)...
The spectrum of resistance in SR/CR mice: the critical role of chemoattraction in the cancer/leukocyte interactionGregory Riedlinger
Department of Pathology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina, 27157, USA
BMC Cancer 10:179. 2010..This resistance is effective against sarcoma 180 (S180) at exceptionally high doses and these mice remain healthy...
Mass spectrometry identification of circulating alpha-1-B glycoprotein, increased in aged female C57BL/6 miceJohn R Stehle
Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Biochim Biophys Acta 1770:79-86. 2007..These results suggest that alpha(1)B-glycoprotein changes in mice in a sex and age dependent manner...
Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killingTimothy E Kute
Department of Pathology, Wake Forest University, Winston Salem, NC, USA
Cancer Immunol Immunother 58:1887-96. 2009....
