CAROL SHIVELY

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Depression and coronary artery atherosclerosis and reactivity in female cynomolgus monkeys
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1040, USA
    Psychosom Med 64:699-706. 2002
  2. ncbi The effects of moderate ethanol consumption on the liver of the monkey, Macaca fascicularis
    Priscilla Ivester
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1016, USA
    Alcohol Clin Exp Res 27:1831-7. 2003
  3. ncbi Social stress, visceral obesity, and coronary artery atherosclerosis: product of a primate adaptation
    Carol A Shively
    Wake Forest University Primate Center, Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina NC 27157 1040, USA
    Am J Primatol 71:742-51. 2009
  4. ncbi Social stress, visceral obesity, and coronary artery atherosclerosis in female primates
    Carol A Shively
    Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 17:1513-20. 2009
  5. ncbi Stress, depression, and coronary artery disease: modeling comorbidity in female primates
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Neurosci Biobehav Rev 33:133-44. 2009
  6. ncbi Depressive behavior and coronary artery atherogenesis in adult female cynomolgus monkeys
    Carol A Shively
    Department of Pathology Section on Comparative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1040, USA
    Psychosom Med 70:637-45. 2008
  7. ncbi Hormone therapy effects on social behavior and activity levels of surgically postmenopausal cynomolgus monkeys
    Carol A Shively
    Department of Pathology Section on Comparative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1040, USA
    Psychoneuroendocrinology 32:981-90. 2007
  8. ncbi Effects of chronic moderate alcohol consumption and novel environment on heart rate variability in primates (Macaca fascicularis)
    Carol A Shively
    Department of Pathology Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1040, USA
    Psychopharmacology (Berl) 192:183-91. 2007
  9. ncbi Behavioral depression and positron emission tomography-determined serotonin 1A receptor binding potential in cynomolgus monkeys
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Arch Gen Psychiatry 63:396-403. 2006
  10. ncbi Social stress-associated depression in adult female cynomolgus monkeys (Macaca fascicularis)
    Carol A Shively
    Department of Pathology Comparative Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1040, USA
    Biol Psychol 69:67-84. 2005

Research Grants

  1. Depression and Coronary Artery Atherosclerosis in Premenopausal Primates
    CAROL SHIVELY; Fiscal Year: 2007
  2. Depression and Coronary Artery Atherosclerosis in Premenopausal
    CAROL SHIVELY; Fiscal Year: 2009
  3. Depression and Coronary Artery Atherosclerosis in Premenopausal
    Carol A Shively; Fiscal Year: 2010

Detail Information

Publications17

  1. ncbi Depression and coronary artery atherosclerosis and reactivity in female cynomolgus monkeys
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1040, USA
    Psychosom Med 64:699-706. 2002
    ..Here we report the results of a comparison of physiological characteristics, coronary artery reactivity, and atherosclerosis in 16 depressed and 26 nondepressed female cynomolgus monkeys...
  2. ncbi The effects of moderate ethanol consumption on the liver of the monkey, Macaca fascicularis
    Priscilla Ivester
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1016, USA
    Alcohol Clin Exp Res 27:1831-7. 2003
    ..This is still a concern because some human studies suggest that levels of ethanol considered to be cardioprotective cause liver injury when consumed over a lifetime...
  3. ncbi Social stress, visceral obesity, and coronary artery atherosclerosis: product of a primate adaptation
    Carol A Shively
    Wake Forest University Primate Center, Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina NC 27157 1040, USA
    Am J Primatol 71:742-51. 2009
    ..Social stress may be engaging these same physiological systems, increasing the visceral deposition of fat and its sequelae, which increase CHD risk...
  4. ncbi Social stress, visceral obesity, and coronary artery atherosclerosis in female primates
    Carol A Shively
    Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 17:1513-20. 2009
    ..Further studies are needed to understand the complex and multifactorial temporal relationship among relative visceral obesity, physiological stress responses, and CAA...
  5. ncbi Stress, depression, and coronary artery disease: modeling comorbidity in female primates
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Neurosci Biobehav Rev 33:133-44. 2009
    ..More study is needed to discriminate between these two possibilities. The primate data paint a compelling picture of depression as a whole-body disease...
  6. ncbi Depressive behavior and coronary artery atherogenesis in adult female cynomolgus monkeys
    Carol A Shively
    Department of Pathology Section on Comparative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1040, USA
    Psychosom Med 70:637-45. 2008
    ..Thus, in prospective studies of depression and CHD, CAA was likely present at baseline in most subjects who experienced cardiac events. Little is known about the relationship between depression and CAA...
  7. ncbi Hormone therapy effects on social behavior and activity levels of surgically postmenopausal cynomolgus monkeys
    Carol A Shively
    Department of Pathology Section on Comparative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1040, USA
    Psychoneuroendocrinology 32:981-90. 2007
    ..Further research is needed to explore social context as an important feature of behavioral response to steroid hormone regimens and to verify and extend knowledge of systemic effects of vaginal ring-delivered progestogens...
  8. ncbi Effects of chronic moderate alcohol consumption and novel environment on heart rate variability in primates (Macaca fascicularis)
    Carol A Shively
    Department of Pathology Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1040, USA
    Psychopharmacology (Berl) 192:183-91. 2007
    ..Although alcohol consumption often increases at times of stress, the interactive effects of stress and chronic moderate alcohol consumption on cardiac regulation have not been studied...
  9. ncbi Behavioral depression and positron emission tomography-determined serotonin 1A receptor binding potential in cynomolgus monkeys
    Carol A Shively
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Arch Gen Psychiatry 63:396-403. 2006
    ..Current animal models of depression are inadequate to further our understanding of depression. New models that allow for analysis of cognitive function and sex differences are needed...
  10. ncbi Social stress-associated depression in adult female cynomolgus monkeys (Macaca fascicularis)
    Carol A Shively
    Department of Pathology Comparative Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1040, USA
    Biol Psychol 69:67-84. 2005
    ..These monkeys may be a useful model of reproductive system-associated mood disorders in females...
  11. ncbi Effects of social status and moderate alcohol consumption on mammary gland and endometrium of surgically postmenopausal monkeys
    Carol A Shively
    Comparative Medicine Section, Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1040, USA
    Menopause 11:389-99. 2004
    ..To evaluate the effects of social subordination stress and chronic moderate alcohol consumption on indices of breast and endometrial cancer risk...
  12. ncbi Triphasic oral contraceptive treatment alters the behavior and neurobiology of female cynomolgus monkeys
    J A Henderson
    Department of Pathology Comparative Medicine, Program in Neuroscience, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1010, USA
    Psychoneuroendocrinology 29:21-34. 2004
    ..These results suggest that this triphasic OC disrupts social behavior, hypothalamic-pituitary-adrenal axis regulation and the underlying central nervous system function...
  13. ncbi Soy and social stress affect serotonin neurotransmission in primates
    C A Shively
    Department of Pathology, Section of Comparative Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Pharmacogenomics J 3:114-21. 2003
    ..Thus, the hormone-induced increase in SERT was accompanied by increased 5-HT synthesis and neuronal firing, which appears biologically reasonable as 5-HT prevented SERT degradation in vitro...
  14. ncbi Effects of long-term moderate alcohol consumption on agonistic and affiliative behavior of socially housed female cynomolgus monkeys (Macaca fascicularis)
    Carol A Shively
    Department of Pathology, Comparative Medicine Section, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157 1040, USA
    Psychopharmacology (Berl) 165:1-8. 2002
    ..However, little is known about the chronic effects of moderate alcohol consumption. Alcohol, even in moderate doses, has immediate and robust effects on behavior...
  15. ncbi The unique value of primate models in translational research. Nonhuman primate models of women's health: introduction and overview
    Carol A Shively
    Wake Forest University Primate Center, Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1040, USA
    Am J Primatol 71:715-21. 2009
    ....
  16. ncbi Health issues in postmenopausal women who drink
    Thomas C Register
    Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
    Alcohol Res Health 26:299-307. 2002
    ..The effects of alcohol consumption on these three diseases in postmenopausal women are reviewed, along with limitations in interpreting results of studies of alcohol's effects on postmenopausal women's health...
  17. ncbi Cognition, mood disorders, and sex hormones
    Carol A Shively
    Department of Pathology (Comparative Medicine, Wake Forest University, School of Medicine, Winston-Salem, NC, USA
    ILAR J 45:189-99. 2004
    ..These studies are best carried out in primate models, which are more similar to humans in neural serotonergic function than other animal models...

Research Grants9

  1. Depression and Coronary Artery Atherosclerosis in Premenopausal Primates
    CAROL SHIVELY; Fiscal Year: 2007
    ....
  2. Depression and Coronary Artery Atherosclerosis in Premenopausal
    CAROL SHIVELY; Fiscal Year: 2009
    ....
  3. Depression and Coronary Artery Atherosclerosis in Premenopausal
    Carol A Shively; Fiscal Year: 2010
    ....