Research Topics
| Ann M PeifferSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Age-related multisensory enhancement in a simple audiovisual detection taskAnn M Peiffer
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Neuroreport 18:1077-81. 2007..Data support the conclusion that differences in multisensory processing for older adults cannot be explained solely by the effects of general cognitive slowing...
Differential effects of radiation and age on diffusion tensor imaging in ratsAnn M Peiffer
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Brain Res 1351:23-31. 2010..These findings suggest that targets of the fWBI-induced change in this model may be the less myelinated or unmyelinated axons, extracellular matrix, or synaptic fields rather than heavily myelinated tracts...
Ethics in 15 min per weekAnn M Peiffer
Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, PP1 7th Floor, Winston Salem, NC 27157, USA
Sci Eng Ethics 17:289-97. 2011..We still struggle with how to accurately assess this behavioral change; although, we present preliminary survey results on the evaluation and impact of this style of curriculum for ethics instruction in our laboratory...
Aging and the interaction of sensory cortical function and structureAnn M Peiffer
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Hum Brain Mapp 30:228-40. 2009..Thus, functional differences in cortical activity between older and younger adults cannot solely be accounted for by differences in gray matter volume...
Cross-modal deactivations during modality-specific selective attentionJennifer L Mozolic
Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
BMC Neurol 8:35. 2008..This study was designed to determine how focusing attention on the auditory or visual modality impacts neural activity in cortical regions responsible for processing stimuli in the unattended modality...
Preservation of crossmodal selective attention in healthy agingChristina E Hugenschmidt
Department of Radiology, ANSIR Laboratory, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Exp Brain Res 198:273-85. 2009..Thus, age-related increases in distractibility across sensory modalities are likely due to mechanisms other than deficits in attentional processing...
The effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate?Merideth A Addicott
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Hum Brain Mapp 30:3102-14. 2009..Our results suggest a limited ability of the cerebrovascular adenosine system to compensate for high amounts of daily caffeine use...
Modality-specific selective attention attenuates multisensory integrationJennifer L Mozolic
Graduate Program in Neuroscience, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Exp Brain Res 184:39-52. 2008....
Power and sample size calculation for neuroimaging studies by non-central random field theorySatoru Hayasaka
Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Neuroimage 37:721-30. 2007..From the simulations, we found that our method was able to estimate power quite accurately. In the fMRI data analysis, despite the small sample size, we were able to determine power and the number of subjects required to detect signals...
Relating imaging indices of white matter integrity and volume in healthy older adultsChristina E Hugenschmidt
Neuroscience Program, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Cereb Cortex 18:433-42. 2008..As such, the ability to detect early white matter alterations may facilitate development of targeted treatments that prevent or slow age-related white matter degradation and associated cognitive sequelae...
Imaging radiation-induced normal tissue injuryMike E Robbins
a Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina
Radiat Res 177:449-66. 2012....
Developing a problem-based learning (PBL) curriculum for professionalism and scientific integrity training for biomedical graduate studentsNancy L Jones
Division Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
J Med Ethics 36:614-9. 2010..Both faculty and students endorsed the active learning approach for these topics, in contrast to a compliance-based approach that emphasises learning rules and regulations...
Methodological considerations for the quantification of self-reported caffeine useMerideth A Addicott
Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Psychopharmacology (Berl) 203:571-8. 2009..However, various self-report measures have different methodologies, and the accuracy of these different methods has not been compared...
Rapid auditory processing and MGN morphology in microgyric rats reared in varied acoustic environmentsAnn M Peiffer
Department of Psychology, University of Connecticut, Unit 4154, 3107 Horse Barn Hill Rd, Storrs, CT 06269-4154, USA
Brain Res Dev Brain Res 138:187-93. 2002..These findings suggest that a more active form of acoustic stimulation (e.g., training) may be required to ameliorate the deleterious behavioral and anatomical consequences of focal microgyric lesions...
Age and experience-related improvements in gap detection in the ratJennifer T Friedman
Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue, Newark, NJ 07102, USA
Brain Res Dev Brain Res 152:83-91. 2004..The present findings also demonstrate maturational improvements in silent gap detection using a pre-pulse inhibition paradigm...
Sex differences in rapid auditory processing deficits in ectopic BXSB/MpJ miceAnn M Peiffer
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Neuroreport 13:2277-80. 2002....
Brain weight differences associated with induced focal microgyriaAnn M Peiffer
Department of Psychology Behavioral Neuroscience Division, University of Connecticut, USA
BMC Neurosci 4:12. 2003..In this experiment, we investigated changes in brain weight as an index of global disruption of neural systems caused by focal damage to the developing cortical plate...
Sex differences in rapid auditory processing deficits in microgyric ratsAnn M Peiffer
Behavioral Neuroscience Division, Department of Psychology, University of Connecticut Unit 4154, 3107 Horse Barn Hill Road, Storrs, CT 06269-4154, USA
Brain Res Dev Brain Res 148:53-7. 2004....
Severity of focal microgyria and associated rapid auditory processing deficitsAnn M Peiffer
Department of Psychology, Behavioral Neuroscience Division, University of Connecticut, 3107 Horse Barn Hill Rd. U-4154, Storrs, CT 06269-4154, USA
Neuroreport 15:1923-6. 2004..Greater disruptions are also seen in the MGN of double-pair compared to single-pair bilateral microgyric subjects...
Use of a modified prepulse inhibition paradigm to assess complex auditory discrimination in rodentsR Holly Fitch
Department of Psychology, Division of Behavioral Neuroscience, University of Connecticut, 406 Babbidge Rd, Box U 1020, Storrs, CT 06269, United States
Brain Res Bull 76:1-7. 2008..The purpose of the current review is to provide a background on the PPI paradigm, and to summarize what has been learned more recently using modified versions of PPI with rodent models...
Impaired gap detection in juvenile microgyric ratsAnn M Peiffer
Behavioral Neuroscience Division, Department of Psychology, University of Connecticut, 3107 Horse Barn Hill Road, Unit 4154, Storrs, CT 06269-4154, USA
Brain Res Dev Brain Res 152:93-8. 2004..g., simple gap detection), but may require "higher-order" auditory discrimination tasks (e.g., tone sequences, phonemic discriminations) to be elicited later in life...
Auditory processing deficits in rats with neonatal hypoxic-ischemic injuryMelissa M McClure
Department of Psychology, Behavioral Neuroscience Division, Unit 4154, 3107 Horse Barn Hill Rd, Storrs, CT 06269-4154, USA
Int J Dev Neurosci 23:351-62. 2005..As such, the current model may have critical implications for the study of neurophysiological underpinnings of cognitive deficits in premature/VLBW infants...
Research Grants
- Aging and Unisensory Influence of Multisensory ProcessingANN PEIFFER; Fiscal Year: 2007..Taking the information gained by this proposal, older adults can be given new techniques for maintaining their day to day activity level within the community by maximizing the benefits of this sensory cross-talk. ..
