Research Topics
Genomes and Genes | Jill A OharSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Publications
Do symptoms predict COPD in smokers?Jill A Ohar
Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Chest 137:1345-53. 2010..The US Preventive Services Task Force recommends against spirometry in the absence of symptoms. However, as much as 50% of COPD cases in the United States remain undiagnosed...- Changing patterns in asbestos-induced lung diseaseJill Ohar
Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1054, USA
Chest 125:744-53. 2004..To determine patterns in asbestos-induced lung diseases found in older, less exposed workers... - COPD is associated with a macrophage scavenger receptor-1 gene sequence variationJill A Ohar
Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Chest 137:1098-107. 2010.... - Identification of a mesothelioma phenotypeJill A Ohar
Wake Forest University School of Medicine, Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Winston Salem, NC 27157 1054, USA
Respir Med 101:503-9. 2007..We propose that this phenotype be applied to candidate gene analysis... - Reconsidering sex-based stereotypes of COPDJill Ohar
Section on Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Prim Care Respir J 20:370-8. 2011.... - Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokersAlireza Sadeghnejad
Center for Human Genomics and Department of Medicine and Pediatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Respir Res 10:21. 2009..We evaluated the association between polymorphisms in ADAM33 gene with COPD and lung function in long term tobacco smokers... - IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung functionAlireza Sadeghnejad
Center for Human Genomics and Department of Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Am J Respir Crit Care Med 176:748-52. 2007..IL-13 is involved in pulmonary inflammation, remodeling, and susceptibility to chronic obstructive pulmonary disease (COPD)... - Association studies of serum prostate-specific antigen levels and the genetic polymorphisms at the androgen receptor and prostate-specific antigen genesJianfeng Xu
Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Cancer Epidemiol Biomarkers Prev 11:664-9. 2002..A systematic approach is required to identify sequence variants in these genes and other related genes, and to test for an association between these variants and PSA levels in large samples... - Optimum bronchodilator combinations in chronic obstructive pulmonary disease: what is the current evidence?Matthew C Miles
Division of Pulmonary, Critical Care, Allergy, and Immunologic Disease, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
Drugs 72:301-8. 2012.... - Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levelsScott D Cramer
Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Natl Cancer Inst 95:1044-53. 2003..However, polymorphisms associated with variations in PSA levels have not been identified... - Mono- and combination therapy of long-acting bronchodilators and inhaled corticosteroids in advanced COPDJill A Ohar
Section of Pulmonary, Critical Care, Allergy, and Immunologic Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Semin Respir Crit Care Med 31:321-33. 2010..Bronchodilators and their combination with ICS are central to the management of COPD. The choice of agents is based primarily on disease stage, individual response, cost, side effect profile, and availability... - Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer riskJianfeng Xu
Center for Human Genomics and the Department of Public Health, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Nat Genet 32:321-5. 2002..009). Among African American men, these values were 12.5% and 1.8%, respectively (P = 0.01). These results show that MSR1 may be important in susceptibility to prostate cancer in men of both African American and European descent... - Mesothelioma: you do not have to work for itElizabeth J Ampleford
Center for Human Genomics, Wake Forest University, School of Medicine, Winston Salem, North Carolina, USA
Diagn Cytopathol 35:774-7. 2007..Bystander exposures may result in earlier age of disease onset and more aggressive disease progression as described in the following 3 case reports... - Effects of corticosteroids on lung function in asthma and chronic obstructive pulmonary diseaseJames F Donohue
Department of Pulmonary and Critical Care Medicine, University of North Carolina at Chapel Hill, 4125 Bioinformatics Bldg, CB 7020, Chapel Hill, NC 27599 7020, USA
Proc Am Thorac Soc 1:152-60. 2004..Some evidence suggests that patients with COPD who respond to corticosteroids have eosinophilic inflammation and other attributes of an asthma phenotype...