Research Topics
| Thomas L EllisSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Detail Information
Publications
A parametric study delineating irreversible electroporation from thermal damage based on a minimally invasive intracranial procedurePaulo A Garcia
Bioelectromechanical Systems Laboratory, School of Biomedical Engineering and Sciences, Virginia Tech Wake Forest University, Blacksburg, VA, USA
Biomed Eng Online 10:34. 2011....
Deep brain stimulation for medically refractory epilepsyThomas L Ellis
Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Neurosurg Focus 25:E11. 2008..More studies are necessary to determine if there is an appropriate population of seizure patients for DBS, the optimal target, and the most efficacious stimulation parameters...
OligodendrogliomaThomas L Ellis
Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC 27105, USA
Curr Treat Options Oncol 4:479-90. 2003..In addition, selected patients should receive chemotherapy. Clinical trials remain critical to advancing our understanding of these tumors and improving our ability to cure these patients...
Toxicity of gamma knife radiosurgery in the treatment of intracranial tumors in patients with collagen vascular diseases or multiple sclerosisDot Lowell
Department of Radiation Oncology, School of Medicine, Wake Forest University, Winston Salem, NC 27157, USA
Int J Radiat Oncol Biol Phys 81:e519-24. 2011..To assess toxicity in patients with either a collagen vascular disease (CVD) or multiple sclerosis (MS) treated with intracranial radiosurgery...
Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasisCourtney A Jensen
Department of Radiation Oncology, Wake Forest University, Winston Salem, North Carolina, USA
J Neurosurg 114:1585-91. 2011..As a strategy to delay or avoid whole-brain radiotherapy (WBRT) after resection of a brain metastasis, the authors used high-resolution MR imaging and cavity-directed radiosurgery for the detection and treatment of further metastases...
Repeat gamma knife radiosurgery for trigeminal neuralgiaAdam C Aubuchon
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Int J Radiat Oncol Biol Phys 81:1059-65. 2011..The present series summarized the results of a repeat treatment series at Wake Forest University Baptist Medical Center, including a multivariate analysis of the data to identify the prognostic factors for treatment success and toxicity...
Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobaltChristopher J Balamucki
Department of Neurosurgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1030, USA
J Neurosurg 105:730-5. 2006..CONCLUSIONS: Patients with facial pain appear to receive consistent treatment with GKS at any time during the first half-life of the Co sources...
Gamma Knife surgery targeting the resection cavity of brain metastasis that has progressed after whole-brain radiotherapyPaul K Kim
Department of Neurosurgery, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Neurosurg 105:75-8. 2006..The authors describe their experience in using Gamma Knife surgery (GKS) to target the resection cavity in patients whose tumors had progressed after WBRT...
Predictive variables for the successful treatment of trigeminal neuralgia with gamma knife radiosurgeryKopriva Marshall
Department of Radiation Oncology, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
Neurosurgery 70:566-72; discussion 572-3. 2012..Gamma Knife radiosurgery (GKRS) has been reported to be an effective modality to treat trigeminal neuralgia...
Staged gamma knife radiosurgery for large cerebral arteriovenous malformationsKwame Amponsah
Department of Neurosurgery, Wake Forest University Baptist Medical Center, Winston Salem, NC 27157, USA
Stereotact Funct Neurosurg 89:365-71. 2011..We present our experience over a 10-year period of staged radiosurgery for large arteriovenous malformations (AVMs) including patient outcomes and methods...
Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: a single-institution retrospective reviewPaul A Saconn
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Int J Radiat Oncol Biol Phys 78:1142-6. 2010..To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning...
Angiocentric glioma: a case report and review of the literatureRyan T Mott
Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Diagn Cytopathol 38:452-6. 2010..We also compare and contrast AG to other entities in the differential diagnosis and include a review of the literature...
Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumorsStacy Wentworth
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC, USA
Int J Radiat Oncol Biol Phys 73:208-13. 2009..Patients with neurofibromatosis (NF) develop tumors of the central nervous system (CNS). Radiation therapy (RT) is used to treat these lesions. To better define the efficacy of RT in these patients, we reviewed our 20-year experience...
The role of radiosurgery in the management of malignant brain tumorsVolker W Stieber
Department of Radiation Oncology, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
Curr Treat Options Oncol 6:501-8. 2005..In selected patients with brain metastases, it is also rational to withhold WBRT in favor of radiosurgery alone, with WBRT reserved for salvage without a decrease in median survival time...
A phase II trial of thalidomide and procarbazine in adult patients with recurrent or progressive malignant gliomasJimmy Ruiz
Section on Hematology and Oncology, Department of Internal Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Neurooncol 106:611-7. 2012..6 months (95% CI, 3.5-9.4). Grade 3/4 drug related toxicity was minimal. Quality of life diminished over time. The combination of thalidomide and procarbazine demonstrated no efficacy in this trial...
Rare intraparenchymal choroid plexus carcinoma resembling atypical teratoid/rhabdoid tumor diagnosed by immunostaining for INI1 proteinE Andrew Stevens
Department of Neurosurgery, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Neurosurg Pediatr 4:368-71. 2009..5 years after treatment, which supports the diagnosis of CPC over AT/RT. This case emphasizes the importance of immunostaining for INI1 protein for distinguishing CPC from AT/RT in cases with atypical or indeterminate features...
Reducing set-up uncertainty in the Elekta Stereotactic Body Frame using Stealthstation softwareWilliam H Hinson
Department of Radiation Oncology, Wake Forest University, School of Medicine, Winston Salem, North Carolina 27157, USA
Technol Cancer Res Treat 6:181-6. 2007..6 mm accuracy of phantom-to-SBF alignment was measured. The results on four actual patients showed setup errors of 1.5 mm or less. Using the Stealth Station process, rapid confirmation of alignment on the treatment table is possible...
Weight change following deep brain stimulation for movement disordersRoy E Strowd
Department of Neurology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Neurol 257:1293-7. 2010..Significant mean weight gain of 2.3 kg (p = 0.0124) or 4.2% was observed in our PD patients. Most patients with PD and ET gain weight following DBS, and this gain is not predicted by age, gender, diagnosis, or stimulation target...
Reduced ratio of afferent to total vascular density in mesial temporal sclerosisRyan T Mott
From the Department of Pathology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Neuropathol Exp Neurol 68:1147-54. 2009..e. remnants of regressing vasculature) were also observed in Ammon's horn, suggesting vascular degeneration in the MTS hippocampus. These findings may help further our understanding of the pathophysiology of MTS...
Glossopharyngeal neuralgia treated with gamma knife surgery: treatment outcome and failure analysis. Case reportVolker W Stieber
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1030, USA
J Neurosurg 102:155-7. 2005..The authors present the first report of GKS-treated GPN in a patient who presented with severe, poorly controlled GPN and who refused MVD...
Deep brain stimulation: treating neurological and psychiatric disorders by modulating brain activityMustafa Saad Siddiqui
Movement Disorders Section, Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC 27012, USA
NeuroRehabilitation 23:105-13. 2008
Current controversies in the radiotherapeutic management of adult low-grade gliomaEdward G Shaw
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Semin Oncol 31:653-8. 2004..Further prospective clinical trials are needed to define the optimal management strategy for adults with supratentorial LGG. The schemata from recently completed and ongoing LGG studies will be presented...
Nonthermal irreversible electroporation for intracranial surgical applications. Laboratory investigationThomas L Ellis
Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
J Neurosurg 114:681-8. 2011..This paper evaluates the safety of an NTIRE procedure to lesion normal canine brain tissue...
The role of surgery, radiosurgery and whole brain radiation therapy in the management of patients with metastatic brain tumorsThomas L Ellis
Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Int J Surg Oncol 2012:952345. 2012..Further prospective trials are necessary to continue to elucidate factors that will help triage patients to the proper brain-directed therapy for their cancer...
The use of a Leksell-BRW adapter for linac radiosurgery as an adjunct to Gamma Knife treatmentKenneth E Ekstrand
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
Phys Med Biol 48:4105-10. 2003..We have found that with this device objects within a head phantom can be targeted by the linear accelerator within an accuracy of approximately 1 mm...
Salvage retreatment after failure of radiosurgery in patients with arteriovenous malformationsKelly D Foote
Department of Neurological Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
J Neurosurg 98:337-41. 2003....
Results of a phase II trial of the GliaSite radiation therapy system for the treatment of newly diagnosed, resected single brain metastasesLisa R Rogers
Department of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan 48109 0316, USA
J Neurosurg 105:375-84. 2006..The primary end point of the study was local tumor control. The secondary end points included patient survival, distant brain recurrence, quality of life, and treatment toxicity...
