Research Topics
| A L ThrockmortonSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
| Collaborators
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Detail Information
Publications
Numerical and experimental analysis of an axial flow left ventricular assist device: the influence of the diffuser on overall pump performanceAlexandrina Untaroiu
Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22904 4746, USA
Artif Organs 29:581-91. 2005..The acceptable results of the computational simulations and experimental testing encourage final prototype manufacturing for acute and chronic animal studies...- The status of failure and reliability testing of artificial blood pumpsSonna M Patel
Department of Biomedical Engineering University of Virginia, Charlottesville, VA, USA
ASAIO J 51:440-51. 2005..This detailed literature review has not been published before and provides a thorough documentation of available data and testing procedures regarding failure and reliability of these various pumps... - Filament support spindle for an intravascular cavopulmonary assist deviceAmy L Throckmorton
BioCirc Research Laboratory, Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
Artif Organs 34:1039-44. 2010..5s. These results are acceptable and support the continued development of this cavopulmonary assist device with an outlet spindle to reinforce the protective cage filament design... - Mechanical cavopulmonary assistance of a patient-specific Fontan physiology: numerical simulations, lumped parameter modeling, and suction experimentsAmy L Throckmorton
Department of Mechanical Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA, USA
Artif Organs 35:1036-47. 2011..The suction experiments revealed minimal deformation (<3%) at 9000 rpm. The findings of this study support the continued design and development of this blood pump... - CFD analysis of a Mag-Lev ventricular assist device for infants and children: fourth generation designAmy L Throckmorton
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, Virginia 23284 3015, USA
ASAIO J 54:423-31. 2008..All of these numerical findings are encouraging and demonstrate progress toward achieving a superior pump design... - Pediatric circulatory support: current strategies and future directions. Biventricular and univentricular mechanical assistanceAmy L Throckmorton
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, USA
ASAIO J 54:491-7. 2008..These devices have the potential to generate a paradigm shift in the treatment of the pediatric patients with heart failure--a shift is likely already be underway... - Mechanical axial flow blood pump to support cavopulmonary circulationA L Throckmorton
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, Virginia 23284 USA
Int J Artif Organs 31:970-82. 2008..This blood pump will improve the clinical treatment of patients with failing Fontan physiology and provide a unique catheter-based therapeutic approach as a bridge to recovery or transplantation... - Design of a protective cage for an intravascular axial flow blood pump to mechanically assist the failing FontanAmy L Throckmorton
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA, USA
Artif Organs 33:611-21. 2009..Validation of these flow and performance predictions will be completed in the next round of experimental testing with blood bag evaluation... - Numerical, hydraulic, and hemolytic evaluation of an intravascular axial flow blood pump to mechanically support Fontan patientsAmy L Throckmorton
Department of Mechanical Engineering, School of Engineering, Virginia Commonwealth University, 401 West Main Street, Rm E3221, P O Box 843015, Richmond, VA 23284, USA
Ann Biomed Eng 39:324-36. 2011..These results support the continued development of this intravascular pump as a bridge-to-transplant, bridge-to-recovery, bridge-to-hemodynamic stability, or bridge-to-surgical reconstruction for Fontan patients... - Computational design and experimental performance testing of an axial-flow pediatric ventricular assist deviceAmy L Throckmorton
Department of Biomedical Engineering, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA, USA
ASAIO J 51:629-35. 2005.... - Hydraulic testing of intravascular axial flow blood pump designs with a protective cage of filaments for mechanical cavopulmonary assistJugal Y Kapadia
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, Virginia, USA
ASAIO J 56:17-23. 2010..5-10 L/min at rotational speeds of 4,000-7,000 RPM. Successful development of this blood pump will provide clinicians with a feasible therapeutic option for mechanically supporting the failing Fontan... - Axial flow blood pumpsXinwei Song
Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute University of Virginia, Charlottesville, VA, USA
ASAIO J 49:355-64. 2003..All of these devices demonstrate promise in providing bridge-to-transplant and ultimately destination therapy for adult cardiac failure patients... - Intravascular mechanical cavopulmonary assistance for patients with failing Fontan physiologySonya S Bhavsar
Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
Artif Organs 33:977-87. 2009..25 s. The maximum blood damage index was calculated to be 0.068%. These results support the continued design and development of this cavopulmonary assist device, building upon previous numerical work and experimental prototype testing... - Numerical design and experimental hydraulic testing of an axial flow ventricular assist device for infants and childrenAmy L Throckmorton
Mechanical Engineering Department, School of Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, USA
ASAIO J 53:754-61. 2007..5% with a maximum deviation of 12% at higher flow rates. These hydraulic results demonstrate the excellent performance of the PVAD3 and illustrate the achievement of the design objectives... - Mechanical cavopulmonary assist for the univentricular Fontan circulation using a novel folding propeller blood pumpAmy L Throckmorton
Department of Surgery, Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana corrected USA
ASAIO J 53:734-41. 2007.... - Design and transient computational fluid dynamics study of a continuous axial flow ventricular assist deviceXinwei Song
Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22903, USA
ASAIO J 50:215-24. 2004.... - Computational design and experimental testing of a novel axial flow LVADAlexandrina Untaroiu
Departments of Mechanical and Aerospace Engineering, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22904, USA
ASAIO J 51:702-10. 2005..These acceptable performance results for LEV-VAD design support proceeding with manufacturing of a prototype for extensive mock loop and initial acute animal testing... - Transient and quasi-steady computational fluid dynamics study of a left ventricular assist deviceXinwei Song
Department of Mechanical and Aerospace Engineering, University of Virginia, Charlottesville, Virginia 22904, USA
ASAIO J 50:410-7. 2004..This transient flow analysis can be applied generally in the design process of LVADs; it provides more reliable fluid forces and moments on the impeller for successful design of the magnetic suspension system and motor... - Computational fluid dynamics prediction of blood damage in a centrifugal pumpXinwei Song
Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22903, USA
Artif Organs 27:938-41. 2003..This work ultimately demonstrates that CFD is a convenient and effective approach to analyze the Lagranian behavior of blood in a heart assist device... - Computational analysis of an axial flow pediatric ventricular assist deviceAmy L Throckmorton
Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virgina, Charlottesville, VA 22908, USA
Artif Organs 28:881-91. 2004..08 milliseconds in the pump. This initial design demonstrated acceptable performance, thereby encouraging prototype manufacturing for experimental validation... - Methods of failure and reliability assessment for mechanical heart pumpsSonna M Patel
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22904, USA
Artif Organs 29:15-25. 2005..A descriptive summary of mechanical and human error studies and methods of artificial blood pumps is detailed... - Performance of a 3-bladed propeller pump to provide cavopulmonary assist in the failing Fontan circulationAmy L Throckmorton
Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Ann Thorac Surg 86:1343-7. 2008..We hypothesized that a propeller pump design would function optimally to provide cavopulmonary assist in a univentricular Fontan circulation... - Fluid force predictions and experimental measurements for a magnetically levitated pediatric ventricular assist deviceAmy L Throckmorton
Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22908, USA
Artif Organs 31:359-68. 2007..Following a final design evaluation, a magnetically suspended pediatric VAD will be constructed for extensive hydraulic and animal testing as well as additional validation of this design methodology... - Pediatric circulatory support systemsAmy L Throckmorton
Biomedical Engineering Department, Virginia Artificial Heart Center, University of Virginia, Charlottesville 22903-2442, USA
ASAIO J 48:216-21. 2002..The clinical and experimental success of these support systems provide encouragement to believe that long-term support is possible...