Leng Han

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi CpG island density and its correlations with genomic features in mammalian genomes
    Leng Han
    Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
    Genome Biol 9:R79. 2008
  2. ncbi CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?
    Leng Han
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    BMC Bioinformatics 10:65. 2009
  3. ncbi CpG islands: algorithms and applications in methylation studies
    Zhongming Zhao
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Biochem Biophys Res Commun 382:643-5. 2009
  4. ncbi Contrast features of CpG islands in the promoter and other regions in the dog genome
    Leng Han
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Genomics 94:117-24. 2009
  5. ncbi Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes
    Cizhong Jiang
    Department of Psychiatry and Center for the Study of Biological Complexity, Virginia Commonwealth, USA
    Mol Biol Evol 24:1991-2000. 2007

Detail Information

Publications5

  1. ncbi CpG island density and its correlations with genomic features in mammalian genomes
    Leng Han
    Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
    Genome Biol 9:R79. 2008
    ..To date, there seems to be no comparative analysis of CpG islands and their density at the DNA sequence level among mammalian genomes and of their correlations with other genome features...
  2. ncbi CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?
    Leng Han
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    BMC Bioinformatics 10:65. 2009
    ..Their evaluation suggests that CpGcluster provides a much more efficient approach to detecting functional clusters or islands of CpGs...
  3. ncbi CpG islands: algorithms and applications in methylation studies
    Zhongming Zhao
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Biochem Biophys Res Commun 382:643-5. 2009
    ..Moreover, identification of CGIs is an initial step in many recent studies for predicting methylation status as well as in the design of methylation detection platforms. We reviewed the benchmarks and features used in these studies...
  4. ncbi Contrast features of CpG islands in the promoter and other regions in the dog genome
    Leng Han
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Genomics 94:117-24. 2009
    ..Some genetic or genomic factors such as local recombination rate and karyotype may be related to the unique dog CGI features...
  5. ncbi Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes
    Cizhong Jiang
    Department of Psychiatry and Center for the Study of Biological Complexity, Virginia Commonwealth, USA
    Mol Biol Evol 24:1991-2000. 2007
    ..Our study provides a detailed view of the evolution of promoter-associated CGIs in the human and mouse genomes and our findings are helpful for understanding the evolution of mammalian genomes and the role of CGIs in gene function...