N B Hampson

..Reasons for failure to use CO alarms related largely to lack of knowledge about the devices and motivation...

..This study sought to determine whether prospectively collected symptoms correlate with specific COHB level ranges in a large population of CO-poisoned patients...

..Extensive epidemiologic information about CO poisoning in the United States has been collected, and the utility of partnering with a medical specialty society for disease-specific surveillance demonstrated...

..However, the evidence supporting this concept is scanty. The present study was performed to analyze COHb measurements in a large population of patients with CO poisoning to determine whether clinically significant correlates exist...

..Though smokers are known to have elevated blood carboxyhemoglobin (COHb), due to inhalation of carbon monoxide (CO) in cigarette smoke, limited data exist regarding COHb levels in nonsmokers exposed to secondhand smoke...

..This study was conducted to 1) determine the short-term mortality risk for patients treated with hyperbaric oxygen for CO poisoning, and 2) determine whether any factors related to the poisoning episode are predictive of mortality...

..The objective of this study was to analyze long-term mortality of a large population of CO-poisoned patients treated at one medical center over three decades...

..Although morbidity and mortality from accidental carbon monoxide (CO) poisoning are high in the United States, identification of common but poorly recognized sources should help prevention efforts...

..This study sought to examine trends in other potential indicators of the incidence of carbon monoxide poisoning in the United States...

..Opinions of hyperbaric medicine physicians regarding the treatment of such patients were also sought...

..This study was conducted to assess the stability of COHb in stored and mailed blood samples anticoagulated with heparin...

..Such a trial should attempt to determine the optimal number of HBO2 treatments and the maximum treatment delay from CO poisoning for HBO2 to provide efficacy in patients with specific risk factors for a poor outcome...

..To evaluate the accuracy and quantitate the error of pulse oximetry measurements of arterial oxygenation in patients with severe carbon monoxide (CO) poisoning...

..We sought to assess the utility of routine carboxyhemoglobin measurement and subsequent D(LCO) correction in patients referred for PFT...

..This study sought to describe the population poisoned from CO produced by portable electric generators, and to determine the reasons that generators are operated in a hazardous fashion...

..This study investigated whether pressure changes common to scuba diving and to hyperbaric oxygen therapy would not cause crush damage or leakage from critical seals in commercially available cochlear implants...

..Fewer than one-half of acute care hospitals in a four-state region have the capability to measure COHb levels. This has the potential to significantly impact diagnosis or treatment of patients with acute CO poisoning...

..For various reasons, different hyperbaric facilities offer these treatments once or twice daily and from 5-7 days weekly. It is not known whether the clinical response differs as a result of the rate of administration of HBO2 treatments...

..This study was performed to estimate the number of emergency department (ED) visits annually in the USA for carbon monoxide poisoning...

..Determination of differences in efficacy between treatment protocols will require a large multicenter trial with the use of detailed neurocognitive testing...

..These experiments demonstrate preferential distribution of oxygen to brain during hypercapnia and the ability of NIR spectroscopy to assess regional oxygenation in multiple tissues non-invasively...

..Although it is typically believed that generators were used to power air conditioning and refrigeration, this report demonstrates an unsuspected reason for their use...

..Chronic radiation enteritis develops in 5-20% of patients following abdominal and pelvic radiation. Current treatments are largely ineffective...

..The majority of facilities does not routinely give more than one hyperbaric treatment, but will give repetitive treatment in certain situations...

..It is hoped that each of these lessons are used to develop public programs designed to prevent storm-associated CO poisoning in the future...

..We investigated an outbreak of carbon monoxide (CO) poisoning after a power outage to determine its extent, identify risk factors, and develop prevention measures...

..There are no clinical data to support that any one treatment protocol is superior in out come to any other...

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..CONCLUSIONS: Hyperbaric oxygen therapy for radiation induced hemorrhagic cystitis is an efficacious treatment modality for patients in whom other forms of management have failed...

..Similarly, no trait was identified which might allow elimination of carbon monoxide poisoning from the differential diagnosis of headache...

..Hyperbaric oxygen is generally well tolerated and it remains an important treatment option for managing this common and difficult disease...

..Treatment efficacy was independent of prior intravesical therapy and the timing of radiotherapy...

..Mechanisms and implications are discussed...

..With the availability of new non-invasive measurement technology to detect COHb elevations, emergency clinicians are likely to see COHb elevation as a manifestation of hemolytic anemia...