Robert F Diegelmann

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi Analysis of collagen synthesis
    Robert F Diegelmann
    Department of Biochemistry, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    Methods Mol Med 78:349-58. 2003
  2. ncbi Excessive neutrophils characterize chronic pressure ulcers
    Robert F Diegelmann
    Department of Biochemistry, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298 0614, USA
    Wound Repair Regen 11:490-5. 2003
  3. ncbi Wound healing: an overview of acute, fibrotic and delayed healing
    Robert F Diegelmann
    Department of Biochemistry, Anatomy, Emergency Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298 0614, USA
    Front Biosci 9:283-9. 2004
  4. ncbi Comparison of a new hemostatic agent to current combat hemostatic agents in a Swine model of lethal extremity arterial hemorrhage
    Kevin R Ward
    Department of Emergency Medicine, Virginia Commonwealth University, Virginia Commonwealth University Reanimation Engineering Shock Center, Richmond, Virginia 23298, USA
    J Trauma 63:276-83; discussion 283-4. 2007
  5. ncbi Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing
    Kenneth R Watterson
    Department of Biochemistry, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
    Wound Repair Regen 15:607-16. 2007
  6. ncbi An in silico approach to the analysis of acute wound healing
    Nathan B Menke
    Department of Emergency Medicine, Virginia Commonwealth University, Richmond, Virginia 23284 2014, USA
    Wound Repair Regen 18:105-13. 2010
  7. ncbi Androstenediol reverses steroid-inhibited wound healing
    V Ramana Feeser
    Department of Emergency Medicine, Reanimation, Engineering and Shock Center, VCU Medical Center, Virginia Commonwealth University, 1101 East Marshall Street, Richmond, VA 23298, USA
    Wound Repair Regen 17:758-61. 2009
  8. ncbi Biologic therapeutics and molecular profiling to optimize wound healing
    Marie N Menke
    Department of Obstetrics and Gynecology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA
    Gynecol Oncol 111:S87-91. 2008
  9. ncbi Androstenetriol immunomodulation improves survival in a severe trauma hemorrhage shock model
    Andreea C Marcu
    Virginia Commonwealth University Reanimation Engineering Shock Center VCURES, Virginia Commonwealth University, Richmond, Virginia, USA
    J Trauma 63:662-9. 2007
  10. ncbi How the Wound Healing Society began
    I Kelman Cohen
    Division of Plastic and Reconstructive Surgery, Richmond, Virginia 23298, USA
    Wound Repair Regen 10:195-7. 2002

Research Grants

  1. Signaling in Tissue Injury and Repair
    Robert Diegelmann; Fiscal Year: 2007

Collaborators

Detail Information

Publications16

  1. ncbi Analysis of collagen synthesis
    Robert F Diegelmann
    Department of Biochemistry, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    Methods Mol Med 78:349-58. 2003
  2. ncbi Excessive neutrophils characterize chronic pressure ulcers
    Robert F Diegelmann
    Department of Biochemistry, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298 0614, USA
    Wound Repair Regen 11:490-5. 2003
    ..Furthermore, the persistence of neutrophils and their destructive enzymes appears responsible for the extensive matrix dissociation and thus contributes to the chronicity of these ulcers...
  3. ncbi Wound healing: an overview of acute, fibrotic and delayed healing
    Robert F Diegelmann
    Department of Biochemistry, Anatomy, Emergency Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298 0614, USA
    Front Biosci 9:283-9. 2004
    ..By understanding the functional relationships of these biological processes of normal compared to abnormal wound healing, hopefully new strategies can be designed to treat the pathological conditions...
  4. ncbi Comparison of a new hemostatic agent to current combat hemostatic agents in a Swine model of lethal extremity arterial hemorrhage
    Kevin R Ward
    Department of Emergency Medicine, Virginia Commonwealth University, Virginia Commonwealth University Reanimation Engineering Shock Center, Richmond, Virginia 23298, USA
    J Trauma 63:276-83; discussion 283-4. 2007
    ..We compared the performance of WoundStat (WS) to QCG, HC, AFB, and the new QuikClot zeolite Advance Clotting Sponge (ACS) in a lethal vascular injury model...
  5. ncbi Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing
    Kenneth R Watterson
    Department of Biochemistry, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
    Wound Repair Regen 15:607-16. 2007
    ..Moreover, specific agonists and antagonists of the lysophospholipid receptors may be useful for the treatment of wounds and abnormal wound healing...
  6. ncbi An in silico approach to the analysis of acute wound healing
    Nathan B Menke
    Department of Emergency Medicine, Virginia Commonwealth University, Richmond, Virginia 23284 2014, USA
    Wound Repair Regen 18:105-13. 2010
    ..This model is a step toward constructing an integrative systems biology model of human wound healing...
  7. ncbi Androstenediol reverses steroid-inhibited wound healing
    V Ramana Feeser
    Department of Emergency Medicine, Reanimation, Engineering and Shock Center, VCU Medical Center, Virginia Commonwealth University, 1101 East Marshall Street, Richmond, VA 23298, USA
    Wound Repair Regen 17:758-61. 2009
    ..These findings suggest that restoration of immune regulation by androstenediol can reverse the delayed open wound contraction secondary to steroid stress...
  8. ncbi Biologic therapeutics and molecular profiling to optimize wound healing
    Marie N Menke
    Department of Obstetrics and Gynecology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA
    Gynecol Oncol 111:S87-91. 2008
    ..Non-healing wounds. Emerg Med Rep 2007; 28(4).,Menke NB, Ward KR, Witten TM, Bonchev DG, Diegelmann RF. Impaired wound healing. Clin Dermatol 2007;25:19-25]...
  9. ncbi Androstenetriol immunomodulation improves survival in a severe trauma hemorrhage shock model
    Andreea C Marcu
    Virginia Commonwealth University Reanimation Engineering Shock Center VCURES, Virginia Commonwealth University, Richmond, Virginia, USA
    J Trauma 63:662-9. 2007
    ....
  10. ncbi How the Wound Healing Society began
    I Kelman Cohen
    Division of Plastic and Reconstructive Surgery, Richmond, Virginia 23298, USA
    Wound Repair Regen 10:195-7. 2002
  11. ncbi Protein synthesis inhibition as a potential strategy for metabolic down-regulation
    Melissa C Evans
    Department of Pediatrics, Division of Pediatric Critical Care, VCUHS, P O Box 980530, Richmond, VA 23298 0530, USA
    Resuscitation 73:296-303. 2007
    ..This pilot study tested the potential of puromycin (PUR) to inhibit protein synthesis and reduce oxygen utilization in a non-hibernating, whole animal preparation...
  12. ncbi Wound healing primer
    Stephanie R Goldberg
    Department of Surgery, Virginia Commonwealth University Medical Center, West Hospital, 16th Floor, West Wing, 1200 East Broad Street, Richmond, VA 23298 0645, USA
    Surg Clin North Am 90:1133-46. 2010
    ..To understand how conditions of abnormal wound healing can be corrected, it is important to first understand the basic principles of wound healing...
  13. ncbi Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model
    Nathan J White
    Reanimation Engineering Science Center, Virginia Commonwealth University, Richmond, 23298, USA
    Scand J Trauma Resusc Emerg Med 18:64. 2010
    ..We hypothesize that oxygen transport measurements will be associated with clot strength during traumatic shock, and test this hypothesis using a swine model of controlled traumatic shock...
  14. ncbi Impaired wound healing
    Nathan B Menke
    Department of Emergency Medicine, VCU Reanimation, Engineering and Shock Center, Virginia Commonwealth University Medical Center, Richmond, VA 23298 0614, USA
    Clin Dermatol 25:19-25. 2007
    ..In addition, some initial complexity theoretical models are proposed to define and explain the underlying pathophysiology...
  15. ncbi Androstenetriol improves survival in a rodent model of traumatic shock
    Andreea C Marcu
    Virginia Commonwealth University Reanimation Engineering Shock Center (VCURES, Richmond, VA 23298, USA
    Resuscitation 71:379-86. 2006
    ..05). CONCLUSION: AET significantly improved survival when administered subcutaneously in a single dose in this rodent model of traumatic shock. Further survival and mechanism studies are warranted...
  16. ncbi Molecular markers in patients with chronic wounds to guide surgical debridement
    Harold Brem
    Columbia University College of Physicians and Surgeons, Department of Surgery, Wound Healing and Vascular Biology Laboratory, New York, NY, USA
    Mol Med 13:30-9. 2007
    ..In the future, molecular markers will be developed to identify the nonimpaired tissue, thereby making surgical debridement more accurate and more efficacious...

Research Grants2

  1. Signaling in Tissue Injury and Repair
    Robert Diegelmann; Fiscal Year: 2007
    ..The Program Director has made concerted efforts and will continue to strive to attract underrepresented minorities to apply to this unique training program. ..