Research Topics
| DAVID TABBSummaryAffiliation: Vanderbilt University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Differential localization and dynamics of class I myosins in the enterocyte microvillusAndrew E Benesh
Cell and Developmental Biology Department, Vanderbilt University School of Medicine, Nashville, TN 37205, USA
Mol Biol Cell 21:970-8. 2010....- MyriMatch: highly accurate tandem mass spectral peptide identification by multivariate hypergeometric analysisDavid L Tabb
Mass Spectrometry Research Center Departments of Biomedical Informatics and Biochemistry, Vanderbilt University Medical Center, Nashville, TN 37232 8575, USA
J Proteome Res 6:654-61. 2007..This software and source code is available under Mozilla Public License at this URL: http://www.mc.vanderbilt.edu/msrc/bioinformatics/... - Verification of automated peptide identifications from proteomic tandem mass spectraDavid L Tabb
Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8340, USA
Nat Protoc 1:2213-22. 2006..Examples of ion-trap and tandem time-of-flight (TOF/TOF) mass spectra illustrate these principles of fragmentation... - What's driving false discovery rates?David L Tabb
Department of Biomedical Informatics and Biochemistry, Vanderbilt University, Nashville, Tennessee 37232 8575, USA
J Proteome Res 7:45-6. 2008..Standardizing this assessment should be welcomed as a reflection of the growing impact of proteomic technologies... - DirecTag: accurate sequence tags from peptide MS/MS through statistical scoringDavid L Tabb
Mass Spectrometry Research Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8575, USA
J Proteome Res 7:3838-46. 2008..The source code and binaries for DirecTag are available from http://fenchurch.mc.vanderbilt.edu... - Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approachAnthony J Baucum
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232 0615, USA
Mol Cell Proteomics 9:1243-59. 2010.... - Proteomic analysis of the enterocyte brush borderRussell E McConnell
Dept of Cell and Developmental Biology, Vanderbilt Univ Medical Center, Nashville, TN 37232, USA
Am J Physiol Gastrointest Liver Physiol 300:G914-26. 2011..These results provide a foundation for future studies aimed at defining the molecular mechanisms underpinning brush border assembly and function... - Network-assisted protein identification and data interpretation in shotgun proteomicsJing Li
Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232 8340, USA
Mol Syst Biol 5:303. 2009..In addition, CEA generated a network view of the proteins and helped show the modular organization of proteins that may underpin the molecular mechanisms of the disease... - IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filteringZe Qiang Ma
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8340, USA
J Proteome Res 8:3872-81. 2009..The source code and binaries for the latest version of IDPicker are available from http://fenchurch.mc.vanderbilt.edu/ ... - Proteomic parsimony through bipartite graph analysis improves accuracy and transparencyBing Zhang
Department of Biomedical Informatics, Mass Spectrometry Research Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8575, USA
J Proteome Res 6:3549-57. 2007..We have implemented the tool in the IDPicker package. The source code and binaries for this protein assembly pipeline are available under Mozilla Public License at the following URL: http://www.mc.vanderbilt.edu/msrc/bioinformatics/... - TagRecon: high-throughput mutation identification through sequence taggingSurendra Dasari
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8340, USA
J Proteome Res 9:1716-26. 2010..These results demonstrate the value of using sequence tagging algorithms to fully interrogate clinical proteomic data sets... - Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysisZheng Cao
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
Mol Cell Proteomics 7:1651-67. 2008.... - A proteomics analysis of yeast Mot1p protein-protein associations: insights into mechanismDiana R Arnett
Department of Molecular Physiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
Mol Cell Proteomics 7:2090-106. 2008..We propose that interaction with such a wide range of proteins may be one mechanism through which Mot1p subserves its roles as a transcriptional activator and repressor... - Evaluation of strong cation exchange versus isoelectric focusing of peptides for multidimensional liquid chromatography-tandem mass spectrometryRobbert J C Slebos
Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt Ingram Cancer Center, Medical Research Building III, 465 21st Avenue South, Nashville, Tennessee 37232, USA
J Proteome Res 7:5286-94. 2008..High reproducibility and efficient resolution of IEF peptide separations make the IEF platform superior to the SCX platform for biomarker discovery via shotgun proteomic analyses of tissue specimens... - The enterocyte microvillus is a vesicle-generating organelleRussell E McConnell
Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
J Cell Biol 185:1285-98. 2009..In combination, these data show that microvilli function as vesicle-generating organelles, which enable enterocytes to deploy catalytic activities into the intestinal lumen... - The bis-electrophile diepoxybutane cross-links DNA to human histones but does not result in enhanced mutagenesis in recombinant systemsElisabeth M Loecken
Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
Chem Res Toxicol 22:1069-76. 2009..The extent of DNA cross-linking of isolated histone H2b was similar to that of AGT, suggesting that differences in postcross-linking events explain the difference in mutagenesis...
Research Grants
- New Proteomic Algorithms to Identify Mutant or Modified ProteinsDAVID TABB; Fiscal Year: 2007..We propose new systems for improving proteomics' application to clinical samples by improving identification of modified and mutant protein forms and managing sets of related proteins documentation to promote their widespread use. ..
- New Proteomic Algorithms to Identify Mutant or Modified ProteinsDAVID TABB; Fiscal Year: 2009....
- New Proteomic Algorithms to Identify Mutant or Modified ProteinsDAVID LEE TABB; Fiscal Year: 2010..We propose new systems for improving proteomics'application to clinical samples by improving identification of modified and mutant protein forms and managing sets of related proteins documentation to promote their widespread use. ..
- New Proteomic Algorithms to Identify Mutant or Modified ProteinsDAVID TABB; Fiscal Year: 2009..We propose new systems for improving proteomics' application to clinical samples by improving identification of modified and mutant protein forms and managing sets of related proteins documentation to promote their widespread use. ..