Research Topics
| W A RaySummaryAffiliation: Vanderbilt University Country: USA Publications
| Collaborators
|
Detail Information
Publications
COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart diseaseWayne A Ray
Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Lancet 360:1071-3. 2002..93 (1.09-3.42, p=0.024). By contrast, there was no evidence of raised risk of CHD among users of rofecoxib at doses of 25 mg or less or among users of other NSAIDs...- Lipid-lowering agents and the risk of hip fracture in a Medicaid populationW A Ray
Department of Preventive Medicine, Vanderbilt University School of Medicine and the Geriatric Research, Education and Clinical Center, Nashville VAMC, Nashville, Tennessee 37232, USA
Inj Prev 8:276-9. 2002..However, this comparison may be biased by unmeasured factors associated with treated hyperlipidemias... - Misclassification of current benzodiazepine exposure by use of a single baseline measurement and its effects upon studies of injuriesWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, Vanderbilt University School of Medicine, Geriatric Research, Education and Clinical Center, Nashville VAMC, Nashville, TN, USA
Pharmacoepidemiol Drug Saf 11:663-9. 2002..We used data from an historical cohort study to demonstrate the extent of misclassification potentially induced by this practice... - COX-2 selective non-steroidal anti-inflammatory drugs and cardiovascular diseaseWayne A Ray
Vanderbilt University School of Medicine, A-1124, MCN, Nashville, TN 37232, USA
Pharmacoepidemiol Drug Saf 12:67-70. 2003 - Evaluating medication effects outside of clinical trials: new-user designsWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Am J Epidemiol 158:915-20. 2003..This article thus argues that such designs should be used more frequently in pharmacoepidemiology... - Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort studyWayne A Ray
Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Lancet 359:118-23. 2002..We did an observational study to measure the effects of NANSAIDs, including naproxen, on risk of serious coronary heart disease... - Educational program for physicians to reduce use of non-steroidal anti-inflammatory drugs among community-dwelling elderly persons: a randomized controlled trialW A Ray
Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Med Care 39:425-35. 2001..Because NSAIDs frequently cause serious gastrointestinal (GI) and other complications among elderly patients, expert guidelines for osteoarthritis recommend acetaminophen-based regimens, which are safer and often as effective as NSAIDs... - Cyclic antidepressants and the risk of sudden cardiac deathWayne A Ray
Department of Preventive Medicine, Division of Pharmacoepidemiology, Vanderbilt University School of Medicine, A 1124 Medical Center North, Nashville, TN 37232, USA
Clin Pharmacol Ther 75:234-41. 2004..We thus sought to quantify the risk of sudden cardiac death among TCA users, according to dose, as well as among users of selective serotonin reuptake inhibitors (SSRIs)... - Antipsychotics and the risk of sudden cardiac deathW A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Arch Gen Psychiatry 58:1161-7. 2001..The study was conducted before the introduction of risperidone and, thus, did not include the newer atypical agents... - Educational program for nursing home physicians and staff to reduce use of non-steroidal anti-inflammatory drugs among nursing home residents: a randomized controlled trialC M Stein
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Med Care 39:436-45. 2001..5%) and intervention (35.4%) groups had worsening of their arthritis pain score (P = 0.81). CONCLUSIONS: An educational intervention effectively reduced NSAID use in nursing homes without worsening of arthritis pain... - Changes in continuity of enrollment among high-risk children following implementation of TennCareW O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tenn 37232 8555, USA
Arch Pediatr Adolesc Med 153:1145-9. 1999..TennCare, Tennessee's Medicaid managed care program, was introduced in 1994 with the goals of controlling spending and of improving access to health care... - Excess costs from gastrointestinal disease associated with nonsteroidal anti-inflammatory drugsW E Smalley
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, USA
J Gen Intern Med 11:461-9. 1996..01, linear trend). CONCLUSIONS: Nonsteroidal anti-inflammatory drug (NSAID) use in elderly patients was associated with substantial excess costs and utilization of medical care for gastrointestinal disorders... - Possible medication errors in home healthcare patientsS Meredith
Department of Preventive Medicine, Division of Pharmacoepidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
J Am Geriatr Soc 49:719-24. 2001..More-effective methods are needed to improve medication use in this vulnerable population... - Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: a population-based studyM D Holzman
Department of Surgery, Vanderbilt University and Nashville Veteran Affairs Medical Center, TN, USA
J Am Coll Surg 192:17-24. 2001.... - Comparison of perinatal outcomes among TennCare managed care organizationsW O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Pediatrics 104:525-9. 1999..To compare perinatal outcomes among the managed care organizations (MCOs) providing care to beneficiaries enrolled in TennCare, Tennessee's capitated Medicaid managed care program... - Sociodemographic factors identify US infants at high risk of injury mortalityS J Scholer
Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, USA
Pediatrics 103:1183-8. 1999..To identify sociodemographic predictors of infant injury mortality and to compare trends in injury mortality rates for high- and low-risk US infants from 1985 to 1991... - Reserpine reconsidered: no association with serious peptic ulcer diseaseR I Shorr
Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2637
J Gen Intern Med 8:510-2. 1993..5-1.3) among former users. The authors' data provide evidence that reserpine is not associated with ulcer disease in elderly persons and suggest that a history of ulcer disease need not be a contraindication to the use of this drug... - Health plan notification and feedback to providers is associated with increased filling of preventer medications for children with asthma enrolled in MedicaidWilliam O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232 2504, USA
J Pediatr 152:481-8. 2008..To test the hypothesis that children enrolled in Medicaid managed care health plans that provide asthma-specific communication to providers would be more likely to have adequate asthma medication filling... - Cardiovascular toxicity of valdecoxibWayne A Ray
N Engl J Med 351:2767. 2004 - Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control studyDavid J Graham
Office of Drug Safety, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD, USA
Lancet 365:475-81. 2005.... - Inhibition of angiotensin II signaling and recurrence of atrial fibrillation in AFFIRMKatherine T Murray
Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
Heart Rhythm 1:669-75. 2004..We investigated whether inhibition of endogenous angiotensin II signaling reduces the recurrence rate of atrial fibrillation (AF) in patients enrolled in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study... - Resident work hour limits and patient safetyBenjamin K Poulose
Section of Surgical Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Ann Surg 241:847-56; discussion 856-60. 2005..This study evaluates the effect of resident physician work hour limits on surgical patient safety... - Gaps in enrollment from a Medicaid managed care program: effects on emergency department visits and hospitalizations for children with asthmaWilliam O Cooper
Division of General Pediatrics, Vanderbilt Children s Hospital, Nashville, Tennessee 37232 8555, USA
Med Care 43:718-25. 2005..For high-risk children with asthma enrolled in Medicaid, loss of Medicaid coverage is a potential threat to access to quality asthma care... - National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugsNeena S Abraham
Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Texas 77030, USA
Gastroenterology 129:1171-8. 2005..Our objective was to assess adherence to evidence-based guidelines by providers of the Department of Veterans Affairs nationwide... - Prevention of fall-related injuries in long-term care: a randomized controlled trial of staff educationWayne A Ray
Division of Pharmacoepidemiology and Center for Education and Research on Therapeutics, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Arch Intern Med 165:2293-8. 2005..The aim of this study was to test whether a training program in safety practices for staff could reduce fall-related injuries in long-term care facilities... - Trends in prescribing of antipsychotic medications for US childrenWilliam O Cooper
Division of General Pediatrics Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA
Ambul Pediatr 6:79-83. 2006..To identify frequencies of prescribing for antipsychotics among all US children... - Major congenital malformations after first-trimester exposure to ACE inhibitorsWilliam O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
N Engl J Med 354:2443-51. 2006..We conducted a study to assess the association between exposure to ACE inhibitors during the first trimester of pregnancy only and the risk of congenital malformations... - Increasing use of antidepressants in pregnancyWilliam O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232 2504, USA
Am J Obstet Gynecol 196:544.e1-5. 2007..The purpose of this study was to quantify the rate of exposures to antidepressants during pregnancy in a large cohort of women... - Effect of regulatory warnings on antidepressant prescribing for children and adolescentsBenji T Kurian
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Arch Pediatr Adolesc Med 161:690-6. 2007.... - Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibsWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA
Gastroenterology 133:790-8. 2007..However, the relative clinical effectiveness of these therapeutic alternatives is understudied... - Racial differences in antidepressant treatment preceding suicide in a Medicaid populationWayne A Ray
Department of Preventive Medicine, Vanderbilt University, 2600 Village at Vanderbilt, 1500 21st Ave, Nashville, TN 37212, USA
Psychiatr Serv 58:1317-23. 2007..This study assessed whether this racial disparity is present among patients with a very high risk of severe mood disorders--that is, those with completed suicides... - Positive predictive value of computerized records for major congenital malformationsWilliam O Cooper
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 3723 2504, USA
Pharmacoepidemiol Drug Saf 17:455-60. 2008..To assess the positive predictive value of computerized records in a linked database of vital records and infant claims, with medical record confirmation to detect congenital malformations in a Medicaid population... - Adjustment for multiple cardiovascular risk factors using a summary risk scorePatrick G Arbogast
Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232 2158, USA
Epidemiology 19:30-7. 2008..Although this summary score has a number of advantages, there is concern that it may result in underestimation of the standard error of the exposure estimate and thus inflate the number of statistically significant results... - Increasing exposure to angiotensin-converting enzyme inhibitors in pregnancyMichael E Bowen
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
Am J Obstet Gynecol 198:291.e1-5. 2008..The objective of the study was to identify angiotensin-converting enzyme (ACE) inhibitor prescription-filling trends in pregnant women... - Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysisBruce M Psaty
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, USA
JAMA 292:2622-31. 2004..As a result, the challenge of early detection has largely shifted to the US postmarketing systems... - Oral erythromycin and the risk of sudden death from cardiac causesWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine Vanderbilt University School of Medicine, Nashville, USA
N Engl J Med 351:1089-96. 2004..We studied the association between the use of erythromycin and the risk of sudden death from cardiac causes and whether this risk was increased with the concurrent use of strong inhibitors of CYP3A... - Oral corticosteroid use among children in TennCareWilliam O Cooper
Division of General Pediatrics Department of Pediatrics, Vanderbilt University School of Medicine, Suite 5028 MCE, Nashville, TN 37232 8555, USA
Ambul Pediatr 2:375-81. 2002..Documenting patterns of use for medications with potential for suboptimal use and adverse effects, such as oral corticosteroids, would be useful... - Outpatient adherence to beta-blocker therapy after acute myocardial infarctionJaved Butler
Department of Medicine, Cardiology Division, 383 PRB, Vanderbilt University Medical Center, Nashville, TN 37232, USA
J Am Coll Cardiol 40:1589-95. 2002..This study was designed to determine adherence to outpatient beta-blocker therapy following acute myocardial infarction (AMI)... - Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugsWalter Smalley
Vanderbilt University, Nashville, Tennessee 37232, USA
Arthritis Rheum 46:2195-200. 2002..To determine the frequency of use of recommended gastroprotective strategies in a cohort of patients receiving recurrent treatment with nonsteroidal antiinflammatory drugs (NSAIDs)... - Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosisWilliam O Cooper
Division of General Pediatrics, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee 37232 8555, USA
Obstet Gynecol 100:101-6. 2002..To assess the association between prenatal antibiotics, including erythromycin, and infantile hypertrophic pyloric stenosis in a large cohort of infants... - Very early exposure to erythromycin and infantile hypertrophic pyloric stenosisWilliam O Cooper
Department of Pediatrics, Division of General Pediatrics, Vanderbilt University School of Medicine, Suite 5028 MCE, Nashville, TN 37232 8555, USA
Arch Pediatr Adolesc Med 156:647-50. 2002..To assess the link between very early erythromycin exposure and pyloric stenosis in young infants... - Effect of a mental health "carve-out" program on the continuity of antipsychotic therapyWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, Nashville Veterans Affairs Medical Center, Nashville, USA
N Engl J Med 348:1885-94. 2003..We studied the effect of this transition on the continuity of antipsychotic therapy among patients with severe mental illness who had previously adhered to treatment... - Population-based studies of adverse drug effectsWayne A Ray
Division of Pharmacoepidemiology, Department of Preventive Medicine, and the Geriatric Research, Education and Clinical Center, Nashville Veterans Affairs Medical Center, Nashville, USA
N Engl J Med 349:1592-4. 2003 - Health care utilization after medical and surgical therapy for gastroesophageal reflux disease: a population-based study, 1996 to 2000Leena Khaitan
Department of Surgery, Vanderbilt University School of Medicine, Vanderbilt University Center for Education and Research on Therapeutics, Nashville, TN 37232, USA
Arch Surg 138:1356-61. 2003..85 in year 3, and 0.74 vs 0.90 in year 4). CONCLUSION: The utilization of health care resources in patients treated surgically for GERD is associated with a modest decrease in the use of GERD-related medications and GERD-related visits... - High frequency of use of rofecoxib at greater than recommended doses: cause for concernMarie R Griffin
Department of Preventive Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Pharmacoepidemiol Drug Saf 13:339-43. 2004..Thus chronic use of high doses of rofecoxib has implications for patient safety... - New users of antipsychotic medications among children enrolled in TennCareWilliam O Cooper
Division of General Pediatrics, Department of Pediatrics, Vanderbilt University School of Medicine, Suite 5028 MCE, Nashville, TN 37232 8555, USA
Arch Pediatr Adolesc Med 158:753-9. 2004.... - Prescriptions for contraindicated category X drugs in pregnancy among women enrolled in TennCareWilliam O Cooper
Division of General Pediatrics Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8555, USA
Paediatr Perinat Epidemiol 18:106-11. 2004.... - Aspirin: redundant in users of nonaspirin, nonsteroidal antiinflammatory agents?Wayne A Ray
Am Heart J 143:381-2. 2002 - A population-based study of survival among elderly persons diagnosed with colorectal cancer: does race matter if all are insured? (United States)Selwyn O Rogers
Department of Surgery Meharry Medical College, Nashville, TN 37232, USA
Cancer Causes Control 15:193-9. 2004..We examined the effect of race on CRC outcomes in a population-based study of elderly Tennesseeans who had identical healthcare coverage - simultaneous enrollment in both Medicaid and Medicare... - Postmarketing surveillance for drug safety: surely we can do betterMarie R Griffin
Department of Preventive Medicine, Vanderbilt University Medical Center, and Geriatric Research and Education Clinical Center, Veterans Affairs Tennessee Valley Healthcare System, Nashville, 37232, USA
Clin Pharmacol Ther 75:491-4. 2004 - Outpatient utilization of angiotensin-converting enzyme inhibitors among heart failure patients after hospital dischargeJaved Butler
Department of Preventive Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
J Am Coll Cardiol 43:2036-43. 2004..This study was designed to assess outpatient angiotensin-converting enzyme inhibitor (ACEI) use after heart failure (HF) hospitalization... - Learning from aprotinin--mandatory trials of comparative efficacy and safety neededWayne A Ray
N Engl J Med 358:840-2. 2008 - Reform of drug regulation--beyond an independent drug-safety boardWayne A Ray
Center for Education and Research on Therapeutics, Vanderbilt University School of Medicine, Nashville, USA
N Engl J Med 354:194-201. 2006 - Antipsychotics and sudden death: is thioridazine the only bad actor?Wayne A Ray
Br J Psychiatry 180:483-4. 2002 - Observational studies of drugs and mortalityWayne A Ray
Center for Education and Research on Therapeutics, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, USA
N Engl J Med 353:2319-21. 2005 - Improving medication use in newly admitted home healthcare patients: a randomized controlled trialSarah Meredith
Department of Preventive Medicine, Division of Pharmacoepidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
J Am Geriatr Soc 50:1484-91. 2002..CONCLUSIONS: A program congruent with existing personnel and practices of home health agencies improved medication use in a vulnerable population and was particularly effective in reducing therapeutic duplication...