Research Topics
Species | Pratik PandharipandeSummaryAffiliation: Vanderbilt University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Sedation in the intensive care unitS McGrane
Department of Anesthesiology and Critical Care, Vanderbilt University School of Medicine, Nashville, TN, USA
Minerva Anestesiol 78:369-80. 2012....- Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patientsStuart McGrane
Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, 526 MAB, 1211 21st Ave South, Nashville, TN 37212, USA
Crit Care 15:R78. 2011..This study sought to investigate the relationship between two inflammatory biomarkers, procalcitonin and C-reactive protein (CRP), and duration of acute brain dysfunction in ventilated patients... - Bench-to-bedside review: delirium in ICU patients - importance of sleep deprivationGerald L Weinhouse
Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Crit Care 13:234. 2009..Sleep deprivation may prove to be a modifiable risk factor for the development of delirium with important implications for the acute and long-term outcome of critically ill patients... - Liberation and animation for ventilated ICU patients: the ABCDE bundle for the back-end of critical carePratik Pandharipande
Anesthesiology Service, VA TN Valley Health Care System, 1310 24th Ave South, Nashville 37212, USA
Crit Care 14:157. 2010.... - Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trialPratik P Pandharipande
Anesthesiology Service, VA TN Valley Health Care System, Nashville, TN 37212 2637, USA
Crit Care 14:R38. 2010.... - Plasma tryptophan and tyrosine levels are independent risk factors for delirium in critically ill patientsP P Pandharipande
Division of Critical Care Medicine, Department of Anesthesiology, Vanderbilt Medical Center, 526 MAB, Nashville, TN, 37212, USA
Intensive Care Med 35:1886-92. 2009..This pilot study investigated whether alterations of tryptophan (Trp), phenylalanine (Phe), and tyrosine (Tyr) plasma levels were associated with a higher risk of transitioning to delirium in critically ill patients... - Narcotic-based sedation regimens for critically ill mechanically ventilated patientsPratik Pandharipande
Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Crit Care 9:247-8. 2005..Modifying sedation paradigms utilizing either narcotic-based regimens with remifentanil or fentanyl, or by using alpha2 agonists such as dexmedetomidine may help in improving these outcomes in critically ill patients... - Derivation and validation of Spo2/Fio2 ratio to impute for Pao2/Fio2 ratio in the respiratory component of the Sequential Organ Failure Assessment scorePratik P Pandharipande
Department of Anesthesiology, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA
Crit Care Med 37:1317-21. 2009.... - Sedative and analgesic medications: risk factors for delirium and sleep disturbances in the critically illPratik Pandharipande
Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, 324 MAB, 1313 21st Avenue South, Nashville, TN 37232, USA
Crit Care Clin 22:313-27, vii. 2006.... - Delirium: acute cognitive dysfunction in the critically illPratik Pandharipande
Department of Anesthesiology Division of Critical Care, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Curr Opin Crit Care 11:360-8. 2005..Hence, critical care physicians and nurses should routinely assess their patients for delirium and develop strategies for its prevention and treatment... - Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patientsPratik Pandharipande
Department of Anesthesia Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Anesthesiology 104:21-6. 2006..Sedative and analgesic medications relieve anxiety and pain but may contribute to patients' transitioning into delirium... - Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trialPratik P Pandharipande
Department of Anesthesiology Division of Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
JAMA 298:2644-53. 2007..Dexmedetomidine induces sedation via different central nervous system receptors than the benzodiazepine drugs and may lower the risk of acute brain dysfunction... - Alpha-2 agonists: can they modify the outcomes in the Postanesthesia Care Unit?P Pandharipande
Department of Anesthesiology, Division of Critical Care Medicine, Vanderbilt University School of Medicine, 324 MAB, 21st Ave South, Nashville, TN 37232, USA
Curr Drug Targets 6:749-54. 2005.... - Prevalence and risk factors for development of delirium in burn intensive care unit patientsVivek Agarwal
Vanderbilt School of Medicine, Nashville, Tennessee, USA
J Burn Care Res 31:706-15. 2010..Exposure to benzodiazepines was an independent risk factor for delirium, whereas opiates and methadone reduced the risk of developing delirium, possibly through reduction of pain in these patients... - Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patientsE Wesley Ely
Department of Medicine, Saint Thomas Hospital, and Vanderbilt University Medical Center, Nashville, TN 37232, USA
Crit Care Med 35:112-7. 2007..To test for an association between apolipoprotein E (APOE) genotypes and duration of intensive care unit delirium... - Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patientsPratik Pandharipande
Department of Anesthesia Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
J Trauma 65:34-41. 2008..The purpose of this study was to analyze the prevalence of and risk factors for delirium in surgical and trauma ICU patients... - Feasibility of implementing a reduced fasting protocol for critically ill trauma patients undergoing operative and nonoperative proceduresRobert M Pousman
Department of Anesthesiology, David Geffen School of Medicine at UCLA, West Los Angeles VA, Los Angeles, California, USA
JPEN J Parenter Enteral Nutr 33:176-80. 2009..This prospective, observational cohort study was designed to determine the feasibility of implementing a reduced enteral fasting protocol in mechanically ventilated trauma patients undergoing selected operative and nonoperative procedures... - The complex interplay between delirium, sedation, and early mobility during critical illness: applications in the trauma unitArna Banerjee
Department of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Curr Opin Anaesthesiol 24:195-201. 2011..This review will focus on the epidemiology of these two disease processes and discuss strategies aimed at reducing these devastating complications of critical illness... - Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionalsRina P Patel
School of Medicine RPP, Vanderbilt University School of Medicine, Nashville, TN, USA
Crit Care Med 37:825-32. 2009..Our objective was to assess beliefs and practices regarding ICU delirium and sedation management... - Acute dermal capillary rupture associated with noninvasive blood pressure monitoringMichael W Chester
Department of Anesthesiology, Vanderbilt Medical Center, Nashville, TN 37212 1204, USA
J Clin Anesth 19:473-5. 2007..Anesthesiologists need to be aware that acute dermal capillary rupture, although rare, can occur in patients with thrombocytopenia and/or long-standing diabetes... - Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care UnitHeidi A B Smith
Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA
Crit Care Med 39:150-7. 2011..To validate a diagnostic instrument for pediatric delirium in critically ill children, both ventilated and nonventilated, that uses standardized, developmentally appropriate measurements... - Delirium as a predictor of long-term cognitive impairment in survivors of critical illnessTimothy D Girard
Division of Allergy, Pulmonary, and Critical Care Medicine, Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, and Department of Medicine, Saint Thomas Hospital, Nashville, TN, USA
Crit Care Med 38:1513-20. 2010..To test the hypothesis that duration of delirium in the intensive care unit is an independent predictor of long-term cognitive impairment after critical illness requiring mechanical ventilation... - Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trialTimothy D Girard
Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Crit Care Med 38:428-37. 2010..To demonstrate the feasibility of a placebo-controlled trial of antipsychotics for delirium in the intensive care unit and to test the hypothesis that antipsychotics would improve days alive without delirium or coma... - Delirium: an emerging frontier in the management of critically ill childrenHeidi A B Smith
Pediatrics and Anesthesiology Division of Critical Care, Department of Pediatrics, 5121 Doctor s Office Tower, 2200 Children s Way, Nashville, TN 37232 9075, USA
Crit Care Clin 25:593-614, x. 2009.... - Presence of electroencephalogram burst suppression in sedated, critically ill patients is associated with increased mortalityPaula L Watson
Department of Medicine, Division of Allergy, Pulmonary, and Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
Crit Care Med 36:3171-7. 2008..Burst suppression has never been studied as a potential risk factor for death in patients without a known neurologic disorder or injury... - Delirium in the intensive care unitTimothy D Girard
Department of Medicine Division of Allergy, Pulmonary, and Critical Care Medicine Vanderbilt University School of Medicine 1161 21st Avenue South, Nashville, TN 37232 2650, USA
Crit Care 12:S3. 2008..Strategies for the prevention and treatment of ICU delirium are the subjects of multiple ongoing investigations... - A Bayesian hierarchical nonlinear mixture model in the presence of artifactual outliers in a population pharmacokinetic studyLeena Choi
Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, TN, USA
J Pharmacokinet Pharmacodyn 38:613-36. 2011..We also conducted simulation studies with a varying proportion of the outliers. These simulation results showed that the proposed model can accommodate the outliers well so that the estimated PK parameters are less biased... - Neuroimaging in delirious intensive care unit patients: a preliminary case series reportAlessandro Morandi
Center for Health Services Research Center, Vanderbilt Center for Quality of Aging, Nashville, Tennesee, USA
Psychiatry (Edgmont) 7:28-33. 2010..e. white matter hyperintensities) and short- and long-term neurological outcomes... - Intraoperative risk factors for acute respiratory distress syndrome in critically ill patientsChristopher G Hughes
Department of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, 526 MAB, 1211 21st Ave South, Nashville, TN 37212, USA
Anesth Analg 111:464-7. 2010..However, research examining intraoperative factors such as fluid resuscitation, mechanical ventilation strategies, and blood administration on the postoperative development of ARDS is lacking... - Dolasetron-induced torsades de pointesSarah Turner
Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN 37212, USA
J Clin Anesth 19:622-5. 2007..On transport to the neurological intensive care unit, the patient developed torsades de pointes, requiring cardiopulmonary resuscitation, before a return to normal sinus rhythm... - Implementation, reliability testing, and compliance monitoring of the Confusion Assessment Method for the Intensive Care Unit in trauma patientsStacie L Soja
Department of Pharmacy, Vanderbilt University Medical Center, Nashville, TN 37212, USA
Intensive Care Med 34:1263-8. 2008..To implement delirium monitoring, test reliability, and monitor compliance of performing the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) in trauma patients...