Research Topics
Genomes and Genes
| Chun LiSummaryAffiliation: Vanderbilt University Country: USA Publications
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Detail Information
Publications
GWAsimulator: a rapid whole-genome simulation programChun Li
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Bioinformatics 24:140-2. 2008..AVAILABILITY: The C++ source code, executables for Linux, Windows and MacOS, manual, example data sets and analysis program are available at http://biostat.mc.vanderbilt.edu/GWAsimulator..- Link-based quantitative methods to identify differentially coexpressed genes and gene pairsHui Yu
Bioinformatics Center, Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, P R China
BMC Bioinformatics 12:315. 2011..Especially, the correlation-reversal is easily missed although it probably indicates remarkable biological significance... - Evaluating cost efficiency of SNP chips in genome-wide association studiesChun Li
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Genet Epidemiol 32:387-95. 2008..We illustrate these approaches using five currently available whole genome SNP chips... - Prioritized subset analysis: improving power in genome-wide association studiesChun Li
Department of Biostatistics, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Hum Hered 65:129-41. 2008..Traditional approaches for assessing the overall statistical significance of GWAS results ignore such information by inherently treating all markers equally... - Assessing whether an allele can account in part for a linkage signal: the Genotype-IBD Sharing Test (GIST)Chun Li
Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232 0700, USA
Am J Hum Genet 74:418-31. 2004..This makes our method a new tool for detecting linkage as well as association, especially in regions harboring a candidate gene. We have implemented these methods in the software package GIST (Genotype-IBD Sharing Test)... - Haplotype association analysis for late onset diseases using nuclear family dataChun Li
Department of Biostatistics, Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee 37232 0700, USA
Genet Epidemiol 30:220-30. 2006..We describe likelihood ratio and permutation tests to test for disease-haplotype association, and describe three test statistics that are potentially useful for detecting such an association... - Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese womenWei Zheng
Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
J Natl Cancer Inst 102:972-81. 2010..No risk assessment model that incorporates both genetic and clinical predictors is currently available to predict breast cancer risk in this population... - GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humansDaniel Kurnik
Vanderbilt University, Nashville, TN, USA
Pharmacogenomics 10:1581-7. 2009..We hypothesized that the GRK5 Gln41Leu variant contributes to interindividual variability in response to beta-blockade and to the ethnic difference in sensitivity between black and Caucasian individuals... - Genetic polymorphisms in the MMP-7 gene and breast cancer survivalAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Cancer 124:208-14. 2009..9) and TT (OS HR: 0.3, 95% CI: 0.1-0.8) fared better than patients with AA (p-value for trend: 0.001). Thus, common MMP-7 genetic polymorphisms were found to be significant determinants of survival among Chinese women with breast cancer... - Genetic variations in the ?(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidineDaniel Kurnik
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Circ Cardiovasc Genet 4:179-87. 2011..We examined whether ADRA2A variants are also associated with cardiovascular responses to the selective ?(2)-AR-agonist dexmedetomidine... - A prevalence-based association test for case-control studiesKelli K Ryckman
Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee 37232, USA
Genet Epidemiol 32:600-5. 2008..Therefore, we propose PRAT as a powerful alternative method of testing for association... - Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapyChun Li
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA
Blood 113:3925-30. 2009..08) and VKORC1 (P = .30) were not associated with stable warfarin dose. Thus, much of the information provided by CYP2C9 and VKORC1 genotypes during warfarin initiation is captured by the early INR response... - Common MMP-7 polymorphisms and breast cancer susceptibility: a multistage study of association and functionalityAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
Cancer Res 68:6453-9. 2008..Results from our study suggest that common MMP-7 genetic polymorphisms may contribute to breast cancer susceptibility... - Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviorsJames S Sutcliffe
Center for Molecular Neuroscience, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232 0615, USA
Am J Hum Genet 77:265-79. 2005..In the aggregate, these variants show significant linkage to and association with autism. Our data provide strong support for a collection of multiple, often rare, alleles at SLC6A4 as imposing risk of autism... - Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockadeDaniel Kurnik
Department of Medicine and Pharmacology, Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6602, USA
Pharmacogenet Genomics 18:895-902. 2008..The purpose of this study was to determine whether ethnic differences in response to beta-blockade can be explained by differing distributions of functional genetic variants in the beta1-AR... - Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer ConsortiumQiuyin Cai
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Hum Mol Genet 20:4991-9. 2011..In vitro electrophoretic mobility shift assays demonstrated the potential functional significance of rs10822013. Our results strongly implicate rs10822013 at 10q21.2 as a genetic risk variant for breast cancer among East-Asian women... - Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humansUtkarsh Kohli
Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
Pharmacogenet Genomics 21:171-8. 2011..NET-deficient transgenic mice have elevated blood pressure (BP), heart rate, and catecholamine concentrations. However, the in-vivo effects of common NET variants on cardiovascular regulation at rest and during exercise are unknown... - Evaluation of breast cancer susceptibility loci in Chinese womenJirong Long
Division of Epidemiology, Department ofMedicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 19:2357-65. 2010..Recent genome-wide association studies (GWAS), mostly conducted among women of European ancestry, have identified 16 single-nucleotide polymorphisms (SNP) associated with breast cancer... - Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer StudyQiuyin Cai
Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, B 2104 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2400, USA
Cancer Epidemiol Biomarkers Prev 17:27-32. 2008..Further studies are needed to explore CYP19A1 gene-environment interactions in relation to breast cancer risk... - Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer ConsortiumJirong Long
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
PLoS Genet 6:e1001002. 2010..1 and demonstrate the utility of conducting genetic association studies in populations with different genetic architectures... - Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestryQiuyin Cai
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Cancer Res 71:1344-55. 2011..This association may be explained in part by a putatively functional variant (rs6913578) identified in the region... - Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1Wei Zheng
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
Nat Genet 41:324-8. 2009..01). These results strongly implicate 6q25.1 as a susceptibility locus for breast cancer... - Evaluation of 11 breast cancer susceptibility loci in African-American womenWei Zheng
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 18:2761-4. 2009..The results from this study extend some of the recent GWAS findings to African-Americans and may guide future efforts to identify the causal variants for breast cancer... - Enriching targeted sequencing experiments for rare disease allelesTodd L Edwards
Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, TN 37203, USA
Bioinformatics 27:2112-8. 2011..SampleSeq also can be used to calculate the sample size needed for the resequencing to increase the chance of successful capture of rare alleles of desired frequencies. SOFTWARE: http://biostat.mc.vanderbilt.edu/SampleSeq.. - Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exerciseLaxmi V Ghimire
Department of Medicine, Division of Clinical, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Pharmacogenet Genomics 22:254-60. 2012.... - Novel genetic markers of breast cancer survival identified by a genome-wide association studyXiao Ou Shu
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
Cancer Res 72:1182-9. 2012..39 × 10(-7)). Similar associations were observed for these two SNPs with breast cancer-specific mortality. This study provides strong evidence suggesting that the RAD51L1 gene and a chromosome 16 locus influence breast cancer prognosis... - Longitudinal follow-up of hypermetropic children identified during preschool vision screeningJeffrey D Colburn
Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
J AAPOS 14:211-5. 2010..Early childhood hypermetropia is an important risk factor for the development of amblyopia and esotropia. Understanding the natural history of these complications aids in management decisions... - Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorderDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, USA
Autism Res 1:159-68. 2008..These data further support our hypothesis that genetic susceptibility impacting multiple components of the MET signaling pathway contributes to ASD risk... - Joint modeling of linkage and association: identifying SNPs responsible for a linkage signalMingyao Li
Department of Biostatistics, School of Public Health, and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109 2029, USA
Am J Hum Genet 76:934-49. 2005..Our method provides a new tool for detecting linkage and association and can be extended to study designs that include unaffected family members... - Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancerJirong Long
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
PLoS Genet 8:e1002532. 2012..This study provides strong evidence for a novel breast cancer susceptibility locus represented by rs9485372, near the TAB2 gene (6q25.1), and identifies two possible susceptibility loci located in the ESR1 gene and 11q24.3, respectively... - Variations in the alpha2A-adrenergic receptor gene and their functional effectsDaniel Kurnik
Department of Medicine, Division of Clinical Pharmacology, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, TN 37232 6606, USA
Clin Pharmacol Ther 79:173-85. 2006..The objectives of this study were to systematically search for variants in the ADRA2A gene, to define the gene's haplotype structure, and to examine potential functional effects of these variants... - Effects of environment, genetics and data analysis pitfalls in an esophageal cancer genome-wide association studyAlexander Statnikov
Discovery Systems Laboratory, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA
PLoS ONE 2:e958. 2007..Several recent genome-wide association studies employing these technologies suggest that panels of SNPs can be a useful tool for predicting cancer susceptibility and discovery of potentially important new disease loci... - Genetic determinants of response to warfarin during initial anticoagulationUte I Schwarz
Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA
N Engl J Med 358:999-1008. 2008.... - Morphometric changes in the rat optic nerve following short-term intermittent elevations in intraocular pressureKaren M Joos
Vanderbilt Eye Institute, Vanderbilt University, Nashville, TN 37232, USA
Invest Ophthalmol Vis Sci 51:6431-40. 2010..This study developed a rat model to evaluate the effect of intermittent controlled elevations in IOP on the morphology of the rat optic nerve... - First-time failure rates of candidates for board certification: an educational outcome measureDenis M O'Day
Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Arch Ophthalmol 126:548-53. 2008.... - The failure rate of candidates for board certification: an educational outcome measureChun Li
Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Trans Am Ophthalmol Soc 104:129-42. 2006..Although the eventual certification rate was high, graduates from a substantial minority of programs appeared inadequately prepared to sit the Board's examinations... - The age-dependent effect of anisometropia magnitude on anisometropic amblyopia severityAlejandro Leon
Department of Ophthalmology and Visual Sciences, Nashville, Tennessee 37232 8808, USA
J AAPOS 12:150-6. 2008..We analyzed results from anisometropic patients identified with photoscreening to eliminate this selection bias... - Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese womenZefang Ren
Department of Medicine, Vanderbilt University, Nashville, TN, USA
Cancer Epidemiol Biomarkers Prev 13:1290-5. 2004..05). These results indicated that IGFBP3 polymorphisms may be associated with the level of blood IGFBP-3 protein and an increased risk of breast cancer... - Meta-analysis identifies common variants associated with body mass index in east AsiansWanqing Wen
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Nat Genet 44:307-11. 2012..0 × 10(-7). Findings from this study may shed light on new pathways involved in obesity and demonstrate the value of conducting genetic studies in non-European populations... - Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlatesJacob L McCauley
Center for Human Genetics Research, Department of Molecular Physiology, Vanderbilt University, Nashville, TN, USA
BMC Med Genet 6:1. 2005..Twin and family studies point to a significant genetic etiology, and several groups have performed genomic linkage screens to identify susceptibility loci... - Racial disparity in amniotic fluid concentrations of tumor necrosis factor (TNF)-alpha and soluble TNF receptors in spontaneous preterm birthRamkumar Menon
Perinatal Research Center, Nashville, TN 37203, USA
Am J Obstet Gynecol 198:533.e1-10. 2008..The objective of this study is to examine the inflammatory cytokine, tumor necrosis factor (TNF)-alpha and soluble TNF receptor concentrations (sTNFR1 and sTNFR2) in the amniotic fluid of black and white women at delivery... - Plasma biomarkers of oxidative stress and genetic variants in age-related macular degenerationMilam A Brantley
Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8808, USA
Am J Ophthalmol 153:460-467.e1. 2012.... - Strategy for encoding and comparison of gene expression signaturesYajun Yi
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232 0275, USA
Genome Biol 8:R133. 2007..This novel approach to performing global comparisons of shared microarray data may have enormous value when coupled directly with a shared data repository... - Detecting gene-gene interaction in linkage analysisChun Li
Vanderbilt University Medical Center, Nashville, Tennessee, USA
Curr Protoc Hum Genet . 2005..Three methods of interaction analysis are also reviewed: conditional linkage analysis, ordered subset analysis, and generalized estimating equations... - Use of cox-2 inhibitors in patients with retinal venous occlusive diseaseFranco M Recchia
Departments of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Retina 28:134-7. 2008..To determine the prevalence of prior or current usage of COX-2 inhibitors among patients with retinal venous occlusion (RVO)... - CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degenerationMingyao Li
Department of Biostatistics, 1420 Washington Heights, University of Michigan, Ann Arbor, Michigan 48109, USA
Nat Genet 38:1049-54. 2006..Our results suggest that there are multiple disease susceptibility alleles in the region and that noncoding CFH variants play a role in disease susceptibility... - Biological, clinical and population relevance of 95 loci for blood lipidsTanya M Teslovich
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA
Nature 466:707-13. 2010..Taken together, our findings provide the foundation to develop a broader biological understanding of lipoprotein metabolism and to identify new therapeutic opportunities for the prevention of CAD... - Evaluation of coverage variation of SNP chips for genome-wide association studiesMingyao Li
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Eur J Hum Genet 16:635-43. 2008..These evaluations can reveal the degree of variation of each SNP chip in covering the genome and can facilitate SNP chip comparisons at a finer scale... - Genetic association analysis using data from triads and unrelated subjectsMichael P Epstein
Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA
Am J Hum Genet 76:592-608. 2005..Our approach also allows for flexible modeling and estimation of allele effects, as well as for missing parental data. We illustrate the usefulness of our approach using SNP data from a candidate-gene study of psoriasis... - Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetesKaisa Silander
Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA
Diabetes 53:1141-9. 2004.... - Generation of two distinct functional isoforms of dosage-sensitive sex reversal-adrenal hypoplasia congenita-critical region on the X chromosome gene 1 (DAX-1) by alternative splicingAnwar Hossain
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Mol Endocrinol 18:1428-37. 2004.... - A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14Kaisa Silander
Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA
Diabetes 53:821-9. 2004.... - A statistical reappraisal of the findings of an esophageal cancer genome-wide association studyAlexander Statnikov
Cancer Res 68:3074-5; author reply 3075. 2008 - TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese populationChun Li
Department of Internal Medicine, Wuhan University Zhongnan Hospital, Donghu Road 169, Wuhan 430 071, People s Republic of China
Am J Gastroenterol 100:290-4. 2005..pylori-induced gastric inflammation. The present study aimed to determine the di-allelic polymorphisms of TNF gene and their association with H. pylori infection and gastroduodenal diseases in Chinese population of Han nationality... - Near-infrared fluorescence optical imaging and tomographyMichael Gurfinkel
Department of Chemical Engineering, Texas A and M University, College Station, TX 77843-3122, USA
Dis Markers 19:107-21. 2003..Finally, a critical evaluation of the limitations and the opportunities for future translation of fluorescence-enhanced optical imaging of deep tissues is presented... - A Triassic aquatic protorosaur with an extremely long neckChun Li
Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing 100044, China
Science 305:1931. 2004..This taxon represents unambiguous evidence for a fully aquatic protorosaur. Its extremely elongated neck is explained as an adaptation for aquatic life, perhaps for an increase in feeding efficiency... - Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin VShi Ke
Division of Diagnostic Imaging, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
J Nucl Med 45:108-15. 2004..111)In-Labeled, PEGylated annexin V may be used to assess tumor response to chemotherapy... - New invariant of DNA sequencesChun Li
Department of Mathematics, Bohai University, Jinzhou 121000, PR China
J Chem Inf Model 45:115-20. 2005..The utility of the new parameter is illustrated on the DNA sequences of five species: human, chimpanzee, mouse, rat, and gallus... - A structured kinetic model for suspension cultures of Taxus chinensis var. mairei induced by an oligosaccharide from Fusarium oxysporumChun Li
Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, P.R. China
Biotechnol Lett 25:1335-43. 2003.... - Recognition of protein coding genes in the yeast genome based on the relative-entropy of DNAChun Li
Department of Mathematics, Bohai University, Jinzhou 121000, P R China
Comb Chem High Throughput Screen 9:49-54. 2006..It is found that the number of protein coding genes in the 16 yeast chromosomes is less than or equal to 5,873, significantly coincident with the widely accepted range 5,800-6,000... - An unusual archosaurian from the marine Triassic of ChinaChun Li
Institute of Vertebrate Paleontology and Paleoanthropology, Academia Sinica, P.O. Box 643, Beijing 100044, People's Republic of China
Naturwissenschaften 93:200-6. 2006..Its mosaic anatomy represents a previously unknown ecomorph within primitive archosaurians... - Comparison between two classes of selective EP(3) antagonists and their biological activitiesMichel Belley
Merck Frosst Centre for Therapeutic Research, PO Box 1005, Pointe Claire Dorval, Que, Canada H9R 4P8
Bioorg Med Chem Lett 16:5639-42. 2006..Some of those compounds, including hybrids containing the best structural features of both series, possess K(i) as low as 0.6 nM on the EP(3) receptor... - Similarity of RNA secondary structuresChun Li
Department of Mathematics, Bohai University, Jinzhou 121000, People s Republic of China
J Comput Chem 28:508-12. 2007..The examination of similarities/dissimilarities of a set of RNA secondary structures at the 3'-terminus of different viruses illustrates the utility of the approach... - Association between interleukin-1 gene polymorphisms and Helicobacter pylori infection in gastric carcinogenesis in a Chinese populationChun Li
Department of Internal Medicine and Geriatrics, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan, China
J Gastroenterol Hepatol 22:234-9. 2007..pylori-induced gastric inflammation. The present study aimed to determine polymorphisms of IL-1B and IL-1 receptor antagonist (IL-1RN) genes and their association with H. pylori infection and gastroduodenal diseases in Chinese patients... - A naturally logical representation for DNA primary sequencesChun Li
Department of Mathematics, Bohai University, Jinzhou, PR China
Comb Chem High Throughput Screen 10:277-81. 2007.... - Targeting phosphatidylserine on apoptotic cells with phages and peptides selected from a bacteriophage display libraryRuping Shao
Department of Experimental Diagnostic Imageing, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Mol Imaging 6:417-26. 2007.... - 2-D graphical representation of protein sequences and its application to coronavirus phylogenyChun Li
Department of Mathematics, Bohai University, Jinzhou, PR China
BMB Rep 41:217-22. 2008..As an application, we construct the phylogenetic tree of 56 coronavirus spike proteins. The resulting tree agrees well with the established taxonomic groups... - Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenograftsShi Ke
Division of Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Cancer Res 63:7870-5. 2003..In MDA-MB-468 tumors, our data suggest that EGF-Cy5.5 may be used as a specific NIR contrast agent for noninvasive imaging of EGFr expression and monitoring of responses to molecularly targeted therapy...
Research Grants
- Developing Statistical Methods for Disease Gene DiscoveryMingyao Li; Fiscal Year: 2010..This application proposes developing new statistical methodologies that address a set of unresolved issues. ..