Research Topics
Genomes and GenesSpecies | Alicia Beeghly-FadielSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
MMP9 polymorphisms and breast cancer risk: a report from the Shanghai Breast Cancer Genetics StudyAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Breast Cancer Res Treat 126:507-13. 2011..2, 95% CI: 0.8-1.8). Common genetic variation in MMP9 was not found to be significantly associated with breast cancer susceptibility among participants of the Shanghai Breast Cancer Genetics Study...
E-cadherin polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer StudyAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Institute of Medicine and Public Health, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN 37203 1738, USA
Breast Cancer Res Treat 121:445-52. 2010....
Evaluation of functional genetic variants for breast cancer risk: results from the Shanghai breast cancer studyBen Zhang
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Am J Epidemiol 173:1159-70. 2011..This study also highlights the value of gene-environment interaction analyses in evaluating genetic factors for complex diseases...
Genetic polymorphisms in the MMP-7 gene and breast cancer survivalAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Cancer 124:208-14. 2009..9) and TT (OS HR: 0.3, 95% CI: 0.1-0.8) fared better than patients with AA (p-value for trend: 0.001). Thus, common MMP-7 genetic polymorphisms were found to be significant determinants of survival among Chinese women with breast cancer...
Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survivalNeeraja B Peterson
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Int J Cancer 125:844-50. 2009..Genetic variation in the TIMP-2 and TIMP-3 genes may contribute to individual differences in breast cancer susceptibility and survival...
Genetic variation in VEGF family genes and breast cancer risk: a report from the Shanghai Breast Cancer Genetics StudyAlicia Beeghly-Fadiel
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Cancer Epidemiol Biomarkers Prev 20:33-41. 2011..In addition to mediating aspects of physiologic and pathologic angiogenesis, the VEGF family also contributes to carcinogenesis...
Two-stage case-control study of DNMT-1 and DNMT-3B gene variants and breast cancer riskChuanzhong Ye
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, B 2104, Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2400, USA
Breast Cancer Res Treat 121:765-9. 2010..Our data suggest that there is no apparent association of common DNMT-1 and DNMT-3B polymorphisms with the risk of breast cancer among Chinese women...
Replication study for reported SNP associations with breast cancer survivalAlicia Beeghly-Fadiel
Division of Epidemiology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA
J Cancer Res Clin Oncol 138:1019-26. 2012....
Melatonin pathway genes and breast cancer risk among Chinese womenSandra L Deming
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Institute for Medicine and Public Health, Vanderbilt University School of Medicine, Eighth Floor, Suite 800 2525 West End Ave, Nashville, TN 3720 1738, USA
Breast Cancer Res Treat 132:693-9. 2012....
Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics StudyRyan J Delahanty
Vanderbilt Epidemiology Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
Am J Epidemiol 174:1115-26. 2011..The associations persisted after adjustment for BMI, suggesting that genetic markers of obesity provide value in addition to BMI in predicting endometrial cancer risk...
Her-2/neu amplification and breast cancer survival: results from the Shanghai breast cancer studyAlicia Beeghly-Fadiel
Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Oncol Rep 19:1347-54. 2008..This study supports a negative prognostic role for Her-2/neu in breast cancer survival among a Chinese population, irrespective of whether FISH or CISH is used to detect amplification of the Her-2/neu gene...
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibilityAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 18:1770-6. 2009..4; 95% CI, 0.9-2.4). Together, these findings support a role for MMP-2 genetic variation in breast cancer susceptibility...
Common MMP-7 polymorphisms and breast cancer susceptibility: a multistage study of association and functionalityAlicia Beeghly-Fadiel
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
Cancer Res 68:6453-9. 2008..Results from our study suggest that common MMP-7 genetic polymorphisms may contribute to breast cancer susceptibility...
Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidenceBen Zhang
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Lancet Oncol 12:477-88. 2011..Results have been generally inconsistent. We did a literature search and meta-analyses to provide a synopsis of the current understanding of the genetic architecture of breast-cancer risk...
