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Species | Timothy J WadeSummaryAffiliation: U.S. Environmental Protection Agency Country: USA Publications
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Publications
High sensitivity of children to swimming-associated gastrointestinal illness: results using a rapid assay of recreational water qualityTimothy J Wade
US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC 27711, USA
Epidemiology 19:375-83. 2008..We evaluated the quantitative polymerase chain reaction (QPCR) as a faster method to assess recreational water quality and predict swimming-associated illnesses...- Comment on "Derivation of numerical values for the World Health Organization guidelines for recreational waters"Larry J Wymer
U S Environmental Protection Agency, National Exposure Research Laboratory, 26 West M L King Drive, Cincinnati, OH 45268, USA
Water Res 39:2774-7. 2005.... - Rapidly measured indicators of recreational water quality are predictive of swimming-associated gastrointestinal illnessTimothy J Wade
National Health and Environmental Effects Research Laboratory, Human Studies Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
Environ Health Perspect 114:24-8. 2006..The association between Enterococcus and illness strengthened as time spent swimming in the water increased. This is the first study to show that water quality measured by rapid methods can predict swimming-associated health effects... - Assessing waterborne risks: an introductionGunther F Craun
Gunther F Craun and Associates, 101 West Frederick Street, Suite 207, Staunton, VA 24401, USA
J Water Health 4:3-18. 2006..For example, one author's definition of attributable risk may be quite different from another author's in terms of the population to which the risk may apply and how it should be interpreted... - Do U.S. Environmental Protection Agency water quality guidelines for recreational waters prevent gastrointestinal illness? A systematic review and meta-analysisTimothy J Wade
Epidemiology and Biomarkers Branch, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA
Environ Health Perspect 111:1102-9. 2003..Future studies should focus on the ability of new, more rapid and specific microbial methods to predict health effects, and estimating the risks of recreational water exposure among susceptible persons... - Increased mortality associated with well-water arsenic exposure in Inner Mongolia, ChinaTimothy J Wade
US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, North Carolina, USA
Int J Environ Res Public Health 6:1107-23. 2009..This is the first study to document increased arsenic-associated mortality in the Bayingnormen region of Inner Mongolia... - Rapidly measured indicators of recreational water quality and swimming-associated illness at marine beaches: a prospective cohort studyTimothy J Wade
United States Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, USA
Environ Health 9:66. 2010..In this paper, we report on results from three marine beach sites... - Elevated human telomerase reverse transcriptase gene expression in blood cells associated with chronic arsenic exposure in Inner Mongolia, ChinaJinyao Mo
Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
Environ Health Perspect 117:354-60. 2009..Arsenic exposure is associated with human cancer. Telomerase-containing human telomerase reverse transcriptase (hTERT) can extend telomeres of chromosomes, delay senescence, and promote cell proliferation leading to tumorigenesis... - Modeling Enterococcus densities measured by quantitative polymerase chain reaction and membrane filtration using environmental conditions at four Great Lakes beachesJustin W Telech
National Health and Environmental Effects Research Laboratory, Human Studies Division, US Environmental Protection Agency, MD 58C, Research Triangle Park, NC 27711, USA
Water Res 43:4947-55. 2009..Results also show that models for both methods did not perform well at predicting occurrences in which water quality levels exceeded a threshold... - Elevated ERCC1 gene expression in blood cells associated with exposure to arsenic from drinking water in Inner MongoliaJinyao Mo
Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, North Carolina, USA
Anticancer Res 29:3253-9. 2009..Chronic arsenic exposure has been associated with human cancer. The objective of this study was to investigate the effects of arsenic exposure on a DNA nucleotide excision repair gene, ERCC1, expression in human blood cells... - Did a severe flood in the Midwest cause an increase in the incidence of gastrointestinal symptoms?Timothy J Wade
Human Studies Division, National Health and Environmental Effects Research Laboratory, Epidemiology and Biomarkers Branch, Environmental Protection Agency, Chapel Hill, NC, USA
Am J Epidemiol 159:398-405. 2004..These findings suggest that severe climatic events can result in an increase in the endemic incidence of gastrointestinal symptoms in the United States... - Contact with beach sand among beachgoers and risk of illnessChristopher D Heaney
Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Am J Epidemiol 170:164-72. 2009..Sand contact activities were associated with enteric illness at beach sites. Variation in beach-specific results suggests that site-specific factors may be important in the risk of illness following sand exposure... - Altered gene expression by low-dose arsenic exposure in humans and cultured cardiomyocytes: assessment by real-time PCR arraysJinyao Mo
Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, NC 27599, USA
Int J Environ Res Public Health 8:2090-108. 2011.... - Water quality indicators and the risk of illness at beaches with nonpoint sources of fecal contaminationJohn M Colford
University of California Berkeley, School of Public Health, Division of Epidemiology, Berkeley, CA 94720 7360, USA
Epidemiology 18:27-35. 2007..Few studies have addressed the utility of indicator bacteria where nonpoint sources are the dominant fecal input. Extrapolating current water-quality thresholds to such locations is uncertain... - Inferences drawn from a risk assessment compared directly with a randomized trial of a home drinking water interventionJoseph N S Eisenberg
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48104, USA
Environ Health Perspect 114:1199-204. 2006..Key words: drinking water, gastrointestinal, intervention trial, microbial risk assessment, waterborne pathogens... - A randomized, controlled trial of in-home drinking water intervention to reduce gastrointestinal illnessJohn M Colford
Centers for Occupational and Environmental Health and Family and Community Health, University of California, Berkeley, School of Public Health, Berkeley, CA, USA
Am J Epidemiol 161:472-82. 2005..active) for the entire trial was 0.98 (95% confidence interval: 0.86, 1.10). No reduction in gastrointestinal illness was detected after in-home use of a device designed to be highly effective in removing microorganisms from water... - Arsenic speciation analysis in human salivaChungang Yuan
Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
Clin Chem 54:163-71. 2008..Determination of arsenic species in saliva is potentially useful for biomonitoring of human exposure and studying arsenic metabolism. Arsenic speciation in saliva has not been reported previously... - A review of household drinking water intervention trials and an approach to the estimation of endemic waterborne gastroenteritis in the United StatesJohn M Colford
Division of Epidemiology, School of Public Health, University of California, Berkeley, 140 Warren Hall, MC 7360, Berkeley, CA 94720, USA
J Water Health 4:71-88. 2006..Using this approach we estimate there to be 4.26-11.69 million cases of AGI annually attributable to public drinking water systems in the United States. We believe this preliminary estimate should be updated as new data become available... - A pilot randomized, controlled trial of an in-home drinking water intervention among HIV + personsJohn M Colford
University of California, Berkeley, School of Public Health, Divisions of Epidemiology and Environmental Health Sciences, 140 Warren Hall 7360, Berkeley, CA 94720, USA
J Water Health 3:173-84. 2005..The magnitude of the point estimate of the risk, its consistency with recently published observational data, and its relevance for drinking water choices by immunocompromised individuals support the need for larger trials... - Participant blinding and gastrointestinal illness in a randomized, controlled trial of an in-home drinking water interventionJohn M Colford
School of Public Health, University of California Berkeley, 140 Warren Hall 7360, Berkeley, CA 94720, USA
Emerg Infect Dis 8:29-36. 2002..75, 2.33) and the attributable risk was 0.24 (95% CI -0.33, 0.57). These data confirm that participants can be successfully blinded to treatment group assignment during a randomized trial of an in-home drinking water intervention...