Ann M Richard

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. ncbi Distributed structure-searchable toxicity (DSSTox) public database network: a proposal
    Ann M Richard
    US Environmental Protection Agency, Mail Drop 68, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    Mutat Res 499:27-52. 2002
  2. ncbi AI and SAR approaches for predicting chemical carcinogenicity: survey and status report
    A M Richardt
    U S Environmental Protection Agency, Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    SAR QSAR Environ Res 13:1-19. 2002
  3. ncbi Chemical structure indexing of toxicity data on the internet: moving toward a flat world
    Ann M Richard
    National Center for Computational Toxicology, US Environmental Protection Agency, MD D343 03, Research Triangle Park, NC 27711, USA
    Curr Opin Drug Discov Devel 9:314-25. 2006
  4. ncbi In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project
    Richard S Judson
    National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 118:485-92. 2010
  5. ncbi Endocrine profiling and prioritization of environmental chemicals using ToxCast data
    David M Reif
    National Center for Computational Toxicology, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 118:1714-20. 2010
  6. ncbi Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
    Thomas B Knudsen
    National Center for Computational Toxicology B205 01, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicology 282:1-15. 2011
  7. ncbi DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages
    ClarLynda R Williams-Devane
    National Center for Computational Toxicology, Office of Research and Development, US EPA, Research Triangle Park, NC 27711, USA
    Bioinformatics 25:692-4. 2009
  8. ncbi Exposure science and the U.S. EPA National Center for Computational Toxicology
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 20:231-6. 2010
  9. ncbi Improving structure-linked access to publicly available chemical toxicity information
    Ann M Richard
    US Environmental Protection Agency, Mail Drop 68, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    Curr Opin Drug Discov Devel 5:136-43. 2002
  10. ncbi Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program
    Matthew T Martin
    National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Chem Res Toxicol 23:578-90. 2010

Collaborators

Detail Information

Publications16

  1. ncbi Distributed structure-searchable toxicity (DSSTox) public database network: a proposal
    Ann M Richard
    US Environmental Protection Agency, Mail Drop 68, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    Mutat Res 499:27-52. 2002
    ....
  2. ncbi AI and SAR approaches for predicting chemical carcinogenicity: survey and status report
    A M Richardt
    U S Environmental Protection Agency, Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    SAR QSAR Environ Res 13:1-19. 2002
    ....
  3. ncbi Chemical structure indexing of toxicity data on the internet: moving toward a flat world
    Ann M Richard
    National Center for Computational Toxicology, US Environmental Protection Agency, MD D343 03, Research Triangle Park, NC 27711, USA
    Curr Opin Drug Discov Devel 9:314-25. 2006
    ....
  4. ncbi In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project
    Richard S Judson
    National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 118:485-92. 2010
    ..The U.S. Environmental Protection Agency's ToxCast program aims to address these concerns by screening and prioritizing chemicals for potential human toxicity using in vitro assays and in silico approaches...
  5. ncbi Endocrine profiling and prioritization of environmental chemicals using ToxCast data
    David M Reif
    National Center for Computational Toxicology, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 118:1714-20. 2010
    ..S. EPA's Endocrine Disruptor Screening Program (EDSP) has been charged with screening pesticide chemicals and environmental contaminants for their potential to affect the endocrine systems of humans and wildlife...
  6. ncbi Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
    Thomas B Knudsen
    National Center for Computational Toxicology B205 01, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicology 282:1-15. 2011
    ..The primary dataset, summary data and details on quality control checks are available for download at http://www.epa.gov/ncct/toxcast/...
  7. ncbi DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages
    ClarLynda R Williams-Devane
    National Center for Computational Toxicology, Office of Research and Development, US EPA, Research Triangle Park, NC 27711, USA
    Bioinformatics 25:692-4. 2009
    ..ncbi.nlm.nih.gov). AVAILABILITY: Data files and documentation may be accessed online at http://epa.gov/ncct/dsstox/...
  8. ncbi Exposure science and the U.S. EPA National Center for Computational Toxicology
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 20:231-6. 2010
    ..In addition, common themes inherent throughout National Center for Computational Toxicology research activities are highlighted for emphasis as exposure science advances into the 21st century...
  9. ncbi Improving structure-linked access to publicly available chemical toxicity information
    Ann M Richard
    US Environmental Protection Agency, Mail Drop 68, National Health and Environmental Effects Research Laboratories, Research Triangle Park, NC 27711, USA
    Curr Opin Drug Discov Devel 5:136-43. 2002
    ....
  10. ncbi Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program
    Matthew T Martin
    National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Chem Res Toxicol 23:578-90. 2010
    ....
  11. ncbi Toward a public toxicogenomics capability for supporting predictive toxicology: survey of current resources and chemical indexing of experiments in GEO and ArrayExpress
    ClarLynda R Williams-Devane
    U S EPA Office of Research and Development National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27519, USA
    Toxicol Sci 109:358-71. 2009
    ..Chemical indexing of public genomics databases is a first important step toward integrating chemical, toxicological and genomics data into predictive toxicology...
  12. ncbi Future of toxicology--predictive toxicology: An expanded view of "chemical toxicity"
    Ann M Richard
    National Center for Computational Toxicology, Mail Drop D343-03, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. richard.ann @epa.gov
    Chem Res Toxicol 19:1257-62. 2006
    ....
  13. ncbi Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment
    Barbara A Wetmore
    The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 2137, USA
    Toxicol Sci 125:157-74. 2012
    ..The incorporation of dosimetry and exposure provide necessary context for interpretation of in vitro toxicity screening data and are important considerations in determining chemical testing priorities...
  14. ncbi Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System
    Richard S Judson
    U S EPA, National Center for Computational Toxicology, Research Triangle Park, NC 27709, USA E Mails M T M S G D M R P K D S J V A F S M E A C H A M R
    Int J Mol Sci 13:1805-31. 2012
    ..The entire system is built using open source tools and is freely available to download. This review describes the organization of the data repository and provides selected examples of use cases...
  15. ncbi Toxicity data informatics: supporting a new paradigm for toxicity prediction
    Ann M Richard
    National Center for Computational Toxicology, U S Environmental Protection Agency, Research Triangle Park, NC, 27711
    Toxicol Mech Methods 18:103-18. 2008
    ....
  16. ncbi The ToxCast program for prioritizing toxicity testing of environmental chemicals
    David J Dix
    National Center for Computational Toxicology D343 03, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Toxicol Sci 95:5-12. 2007
    ..The resulting multidimensional data set provides an informatics challenge requiring appropriate computational methods for integrating various chemical, biological, and toxicological data into profiles and models predicting toxicity...