Research Topics
Species | Marianne BarrierSummaryAffiliation: U.S. Environmental Protection Agency Country: USA Publications
| Collaborators
|
Detail Information
Publications
Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout miceMarianne Barrier
Birth Defects Research Laboratory, Division of Genetics and Development, Department of Pediatrics, University of Washington, Seattle, Washington, USA
Birth Defects Res A Clin Mol Teratol 85:732-40. 2009..Previously, our laboratory has shown that embryos overexpressing the 70-Da heat shock proteins (HSPs) Hspa1a and Hspa1b were partially protected from the deleterious effects of exposure to hyperthermia in vitro...
Mouse embryonic stem cell adherent cell differentiation and cytotoxicity (ACDC) assayMarianne Barrier
US EPA, ORD, NHEERL, ISTD, SBB, MD 72, Research Triangle Park, NC 27711, USA
Reprod Toxicol 31:383-91. 2011..The ACDC assay is a technique that can be used to evaluate the effects of xenobiotics on mESC differentiation and cell number using a single assay...
Alterations in gene expression induced in day-9 mouse embryos exposed to hyperthermia (HS) or 4-hydroperoxycyclophosphamide (4CP): analysis using cDNA microarraysSvetlana Mikheeva
Birth Defects Research Laboratory, Division of Genetics and Developmental Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
Toxicol Sci 79:345-59. 2004....
Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assayKelly J Chandler
National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America
PLoS ONE 6:e18540. 2011..Taken together, these results provide an initial characterization of metabolic and regulatory pathways by which some environmental chemicals may act to disrupt ES cell growth and differentiation...
Proteomics in developmental toxicologyMarianne Barrier
Birth Defects Research Laboratory, Division of Genetics and Developmental Medicine, Department of Pediatrics, University of Washington, Box 356320, 1959 NE Pacific Street, Seattle, WA 98195, USA
Reprod Toxicol 19:291-304. 2005..The field of proteomics is expanding rapidly to provide greater volume and quality of protein information to help understand the multifaceted nature of biological systems...
