Research Topics
| Emmanuel E ZervosSummaryAffiliation: University of South Florida Country: USA Publications
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Detail Information
Publications
Differential gene expression in patients genetically predisposed to pancreatic cancerEmmanuel E Zervos
Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA
J Surg Res 135:317-22. 2006..The purpose of this study was to identify novel genes expressed in patients with a presumed genetic predisposition or "familial" PCA...
Lymphatic mapping in solid neoplasms: state of the artEmmanuel E Zervos
Department of Clinical Investigations, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
Cancer Control 9:189-202. 2002..The success of lymphatic mapping in this realm has broadened its application to other solid neoplasms. This update reviews the status of sentinel lymph node biopsy in its most widely cited applications...
EGF receptor antagonism improves survival in a murine model of pancreatic adenocarcinomaAlan J Durkin
University of South Florida College of Medicine, Department of Surgery, Tampa General Hospital, Digestive Disorders Center, Tampa, Florida 33612, USA
J Surg Res 135:195-201. 2006..05, Fisher's exact test). CONCLUSION: EGF receptor antagonism is not only a plausible therapy for treatment of ductal adenocarcinoma of the pancreas, but is also superior to matrix metalloproteinase inhibition alone or in combination...
Differential expression of the Tie-2 receptor and its ligands in human pancreatic tumorsAlan J Durkin
Department of Surgery, University of South Florida College of Medicine and Tampa General Hospital, Digestive Disorders Center, Tampa, FL, USA
J Am Coll Surg 199:724-31. 2004..Differential expression of Ang-2 in human tumors may be useful as a diagnostic and therapeutic target...
TIPS in Florida: is its application a result of evidence-based medicine?Alexander S Rosemurgy
Department of Surgery, University of South Florida College of Medicine, Tampa General Hospital, Tampa, FL 33601, USA
J Am Coll Surg 204:794-801; discussion 801-2. 2007....
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesisMark Bloomston
Department of Surgery, University of South Florida, Tampa, Florida 33601, USA
J Surg Res 102:39-44. 2002..This study demonstrates the potential role of TIMP-1 as a target in gene therapy for pancreatic cancer...
Stage does not predict survival after resection of hilar cholangiocarcinomas promoting an aggressive operative approachEmmanuel E Zervos
Department of Surgery, University of South Florida, Tampa, FL, USA
Am J Surg 190:810-5. 2005..Staging systems should not impact the decision to operate or postoperative management, as all tumors should be aggressively resected and all patients should receive adjuvant treatment...
Improved outcome with cytoreduction versus embolization for symptomatic hepatic metastases of carcinoid and neuroendocrine tumorsDana A Osborne
Digestive Disorders Center, Tampa General Hospital, 1 Davis Island, Tampa, Florida 33601, USA
Ann Surg Oncol 13:572-81. 2006..Cytoreduction should be pursued whenever possible even if complete resection may not be achievable...
Identification of molecular markers specific for pancreatic neuroendocrine tumors by genetic profiling of core biopsiesMark Bloomston
Surgery, Moffitt Cancer Center, Tampa, Florida 33612, USA
Ann Surg Oncol 11:413-9. 2004..These novel markers may prove useful as molecular markers or therapeutic targets unique to pancreatic neuroendocrine tumors...
Portal hypertension: the role of shunting proceduresAlexander S Rosemurgy
Digestive Disorders Center, University of South Florida, Tampa, Florida, USA
Adv Surg 39:315-29. 2005
Assessment of pancreatic neoplasms: review of biopsy techniquesSteven B Goldin
Department of Surgery, Tampa General Hospital, University of South Florida, Davis Island, Tampa, FL 33601, USA
J Gastrointest Surg 11:783-90. 2007..A treatment algorithm for pancreatic neoplasms is then presented...
In-continuity hepatic resection for advanced hilar cholangiocarcinomaEmmanuel E Zervos
Department of Surgery, University of South Florida College of Medicine, Tampa General Hospital, PO Box 1289, Rm F145, Tampa, FL 33601, USA
Am J Surg 188:584-8. 2004..The purpose of this study was to examine outcomes of patients undergoing concomitant hepatectomy and bile duct excision for advanced Klatskin tumors...
Does Barrett's esophagus impact outcome after laparoscopic Nissen fundoplication?Sarah M Cowgill
Digestive Disorders Center, Tampa General Hospital and the Department of Surgery, University of South Florida College of Medicine, PO Box 1289, Room F145, Tampa, FL 33601, USA
Am J Surg 192:622-6. 2006..Regardless of presence of Barrett's, all improve dramatically with laparoscopic Nissen fundoplication. Barrett's esophagus does not impact presentation before or outcome after laparoscopic Nissen fundoplication...
TIPS versus peritoneovenous shunt in the treatment of medically intractable ascites: a prospective randomized trialAlexander S Rosemurgy
Department of Surgery, University of South Florida, Tampa, Florida, USA
Ann Surg 239:883-9; discussion 889-91. 2004....
Patterns of recurrence after sentinel lymph node biopsy for breast cancerBrian D Badgwell
Division of Surgical Oncology, Department of Surgery, Arthur G. James Cancer Hospital, and Richard J. Solove Research Institute, The Ohio State University, Columbus, Ohio 43210, USA
Ann Surg Oncol 10:376-80. 2003..This supports the use of SLNB as the sole axillary staging procedure in SLN-negative patients...
Post-shunt resource consumption favors small-diameter prosthetic H-graft portacaval shunt over TIPS for patients with poor hepatic reserveAlexander S Rosemurgy
Department of Surgery, University of South Florida, Tampa General Hospital, 1 Davis Boulevard, Box 1289, Room F 145, Tampa, FL 33601, USA
Ann Surg 237:820-5; discussion 825-7. 2003..To define the role of surgical shunting for patients with poor hepatic reserve (Child's class C) in the era of TIPS...
Defining the role of the epidermal growth factor receptor in pancreatic cancer grown in vitroAlan J Durkin
Department of Surgery, GI Tumor Program, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, P.O. Box 1289, Room F-145, Tampa, FL 33601, USA
Am J Surg 186:431-6. 2003..05). The EGF augmentation increased proliferation of each cell line but this increase was only significant in AsPc-1. CONCLUSIONS: Inhibition of EGF receptor is a valid therapeutic strategy in pancreatic cancer...
Surgical management of early-stage pancreatic cancerEmmanuel E Zervos
Department of Surgery, University of South Florida, FL, USA
Cancer Control 11:23-31. 2004....
Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trialsMark Bloomston
Department of Surgery, University of South Florida, Tampa, FL 33601, USA
Ann Surg Oncol 9:668-74. 2002..These findings have led to several clinical trials using the MMP inhibitors Marimastat and BAY12-9566. Herein, we discuss the roles of MMPs and their inhibition in pancreatic cancer...
Laparoscopic cholecystectomy: past, present, and futureDana A Osborne
Department of Surgery, College of Medicine, University of South Florida, Tampa, FL, USA
Surg Technol Int 15:81-5. 2006..The authors reviewed evolution of these techniques that included a synopsis of our experience with the three-port cholecystectomy, as well as the future direction of laparoscopic surgery...
Preshunt liver function remains the prominent determinant of survival after portasystemic shuntingSarah M Cowgill
Digestive Disorders Center, Tampa General Hospital and the Department of Surgery, University of South Florida College of Medicine, PO Box 1289, Room F145, Tampa, FL 33601, USA
Am J Surg 192:617-21. 2006..Hepatic dysfunction, as denoted by Child class and MELD, still remains a primary determinant of survival after portasystemic shunting...
H-graft portacaval shunts versus TIPS: ten-year follow-up of a randomized trial with comparison to predicted survivalsAlexander S Rosemurgy
Department of Surgery, University of South Florida College of Medicine Tampa, FL 33601, USA
Ann Surg 241:238-46. 2005..To report long-term outcome of patients undergoing prosthetic 8-mm H-graft portacaval shunts (HGPCS) or TIPS and to compare actual with predicted survival data...
Esophagography predicts favorable outcomes after laparoscopic Nissen fundoplication for patients with esophageal dysmotilitySteven Rakita
Department of Surgery, University of South Florida College of Medicine, Tampa, FL, USA
J Am Coll Surg 201:335-42. 2005..Preoperative esophagography predicts successful outcomes after laparoscopic Nissen fundoplication for patients with manometric esophageal dysmotility...
Sentinel lymph node biopsy results in less postoperative morbidity compared with axillary lymph node dissection for breast cancerWilliam E Burak
Division of Surgical Oncology, Department of Surgery, Ohio State University, N914 Doan Hall, 410 W 10th Ave, Columbus, OH 43210, USA
Am J Surg 183:23-7. 2002..This study was designed to compare the postoperative morbidity and socioeconomic impact of sentinel lymph node biopsy (SLNB) with axillary lymph node dissection (ALND) in patients with early stage breast cancer...
Twenty-millimeter laparoscopic cholecystectomy: fewer ports results in less pain, shorter hospitalization, and faster recoveryDana Osborne
Department of Surgery, Division of Digestive Diseases and Science, University of South Florida, Tampa, Florida 33601, USA
Am Surg 71:298-302. 2005..A modified technique for laparoscopic cholecystectomy poses no increased risk to patients but offers potential for shorter surgery and hospital stays, less need for narcotic analgesia, and faster recovery...
Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancyAlan J Durkin
Department of Surgery, University of South Florida College of Medicine, Tampa General Hospital, Digestive Disorders Center, Tampa, Florida 33601, USA
J Surg Oncol 89:86-90. 2005....
MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancerMark Bloomston
Department of Surgery, University of South Florida, Tampa, Florida 33601, USA
J Surg Res 102:35-8. 2002..e., human). Pharmacologic and gene therapy aimed at disturbing the MMP/TIMP balance in pancreatic cancer should be targeted toward tumor-specific mechanisms and warrants continued investigation...
Management of variceal hemorrhageAlexander S Rosemurgy
University of South Florida, Tampa, USA
Curr Probl Surg 40:263-343. 2003
Laparoscopic resection of extraadrenal pheochromocytomaEmmanuel E Zervos
East Carolina University, Greenville, NC, USA
Ann Surg Oncol 15:499. 2008
