Research Topics
| Ben L ZarzaurSummaryAffiliation: University of Tennessee Country: USA Publications
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Detail Information
Publications
Identifying life-threatening shock in the older injured patient: an analysis of the National Trauma Data BankBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 68:1134-8. 2010..We hypothesized that age x SI would be a better predictor of 48-hour mortality in old patients (age, >55 years) compared with TVS, whereas for young patients (age, <or=55 years), SI would be a better predictor than TVS...
Motor vehicle crashes obesity and seat belt use: a deadly combination?Ben L Zarzaur
Department of Surgery, The University of Tennessee Health Science Center, The University of North Carolina Chapel Hill, Memphis, Tennessee, USA
J Trauma 64:412-9; discussion 419. 2008..We hypothesized that adult nonobese-belted occupants involved in motor vehicle crashes (MVC) have lower mortality and lower frequency of abdominal injury than obese-belted and obese-nonbelted occupants...
Insurance type is a determinant of 2-year mortality after non-neurologic traumaBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Surg Res 160:196-201. 2010..Less is known about the influence of insurance type and long-term mortality following non-NEURO-TRA. We hypothesized that NO-INS would be associated with 2-y mortality after moderate to severe injury...
New vitals after injury: shock index for the young and age x shock index for the oldBen L Zarzaur
Department of Surgery at The University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Surg Res 147:229-36. 2008..Because age negatively impacts physiological reserve, we hypothesized that age multiplied by SI (Age x SI) would be a better predictor of 48 h mortality (48 MORT) compared to heart rate (HR), systolic blood pressure (SBP), or SI...
The real risk of splenectomy after discharge home following nonoperative management of blunt splenic injuryBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 66:1531-6; discussion 1536-8. 2009..The purpose of this study was to analyze, using population-based data, the 180-day risk of splenectomy in a clinically relevant sample...
Efficacy of monotherapy in the treatment of Pseudomonas ventilator-associated pneumonia in patients with traumaLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 66:1052-8; discussion 1058-9. 2009..The relevance of such "synergy" is commonly supposed but poorly supported. The purpose of this study was to evaluate the efficacy of monotherapy in the treatment of Pseudomonas VAP as measured by microbiological resolution...
Beta-adrenergic blockade and traumatic brain injury: protective?Thomas J Schroeppel
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 69:776-82. 2010..We hypothesize that suppression of the catecholamine surge in multiple-injured TBI patients with beta-adrenergic blockade decreases mortality...
Admission ionized calcium levels predict the need for multiple transfusions: a prospective study of 591 critically ill trauma patientsLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:391-5; discussion 395-7. 2011..We hypothesized that admission iCa levels could potentially predict the need for multiple transfusions in critically ill trauma patients...
Necessity of repeat head CT and ICU monitoring in patients with minimal brain injuryTiffany K Bee
Critical Care Trauma Division, Department of General Surgery, University of Tennessee, Memphis, Tennessee 38163, USA
J Trauma 66:1015-8. 2009..In an attempt to better allocate scarce resources, we hypothesized that not only was repeat head CT unnecessary but also routine intensive care unit (ICU) monitoring of these patients with MBI and stable examinations were unnecessary...
Reduction in inadequate empiric antibiotic therapy for ventilator-associated pneumonia: impact of a unit-specific treatment pathwayLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Am Surg 74:516-22; discussion 522-3. 2008..Adherence to a unit-specific pathway for the empiric management of VAP reduces multiple IEAT episodes. By limiting IEAT episodes, resource utilization and hospital mortality are significantly decreased...
Temporary abdominal closure techniques: a prospective randomized trial comparing polyglactin 910 mesh and vacuum-assisted closureTiffany K Bee
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 65:337-42; discussion 342-4. 2008..Some advocate polyglactin mesh (MESH), while others favor vacuum-assisted closure (VAC). We performed a single institution prospective randomized trial comparing morbidity and mortality differences between MESH and VAC...
Impact of airbags on a Level I trauma center: injury patterns, infectious morbidity, and hospital costsRegan F Williams
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 206:962-8; discussion 968-9. 2008..We hypothesized that airbag use would be related to decreased injury severity of motor vehicle collision survivors admitted to a Level I trauma center, leading to a decrease in infectious morbidity and hospital resource use...
Improved survival after hemostatic resuscitation: does the emperor have no clothes?Louis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:97-102. 2011..To help resolve this controversy, we evaluated the temporal relationship between blood product administration and mortality in civilian trauma patients receiving MT...
Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patientsLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 206:984-91; discussion 991-2. 2008..In an attempt to resolve this ongoing dispute, we evaluated the effect of gender on various outcomes in the largest single institutional series of trauma patients reported in the literature after blunt injury...
Long-term survival and return on investment after nonneurologic injury: implications for the elderly trauma patientBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 69:93-8. 2010..The purpose of this study was to evaluate the cost per 2-year survivor stratified by age after moderate- to severe-nonneurologic injury...
Causative pathogen dictates optimal duration of antimicrobial therapy for ventilator-associated pneumonia in trauma patientsLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 212:476-84; discussion 484-6. 2011..The purpose of this study was to determine the appropriate duration of antimicrobial therapy for VAP in trauma patients secondary to hospital-acquired pathogens...
Variation in the use of urgent splenectomy after blunt splenic injury in adultsBen L Zarzaur
From the Division of Trauma and Critical Care, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee
J Trauma 71:1333-9. 2011..The purpose of this study was to determine the role of urgent splenectomy (defined as splenectomy within 6 hours of admission) in the management of BSI as well as the relationship between urgent splenectomy and in-hospital mortality...
A population-based analysis of neighborhood socioeconomic status and injury admission rates and in-hospital mortalityBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 211:216-23. 2010..We hypothesized that injury-related hospitalization rates would vary by N-SES and that N-SES would be related to in-hospital mortality...
Quality of life after abdominal wall reconstruction following open abdomenBen L Zarzaur
Department of Surgery and School of Nursing, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:285-91. 2011..Results after DAWR demonstrate acceptable recurrence, morbidity, and mortality rates. However, little is known about quality of life (QOL) after DAWR. The purpose of this study was to analyze QOL after DAWR...
Impact of a defined management algorithm on outcome after traumatic pancreatic injuryJohn P Sharpe
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma Acute Care Surg 72:100-5. 2012..Consequently, a management algorithm (ALG) was developed and implemented. The purpose of this study was to evaluate the impact of this ALG on outcomes...
Injury location dictates utility of digital rectal examination and rigid sigmoidoscopy in the evaluation of penetrating rectal traumaM Brinson Hargraves
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Am Surg 75:1069-72. 2009..RS proved better than DRE for diagnosis. The greatest benefit was observed with EP injuries. The possibility of a missed IP injury associated with a negative screen should prompt exploration if clinical suspicion is high...
Minor trauma is an unrecognized contributor to poor fetal outcomes: a population-based study of 78,552 pregnanciesPeter E Fischer
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
J Trauma 71:90-3. 2011..The purpose of this study was to determine the association of both minor and severe injury on fetal demise and prematurity/low birth weight (LBW) in a large population-based study using robust state databases...
Initial chest CT obviates the need for repeat chest radiograph after penetrating thoracic traumaLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Am Surg 73:569-72; discussion 572-3. 2007....
Play or pay: a financial model for trauma care in a regional trauma systemBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma Acute Care Surg 72:78-83; discussion 83-5. 2012..5 million per year. Funds generated are distributed for uncompensated care to hospitals participating in the trauma system. The purpose of this study was to evaluate the effect of PoP on a bordering state's Level I trauma center...
Impact of decompressive craniectomy on functional outcome after severe traumatic brain injuryRegan F Williams
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 66:1570-4; discussion 1574-6. 2009..The purpose of this study was to evaluate the efficacy of DC on functional outcome after severe TBI in the largest single institutional series reported in the literature...
Improving the screening criteria for blunt cerebrovascular injury: the appropriate role for computed tomography angiographyKatrina P Emmett
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:1058-63; discussion 1063-5. 2011..We sought to refine screening criteria for BCVI to optimize patient care...
Superselective catheterization and embolization as first-line therapy for lower gastrointestinal bleedingHeather B Neuman
Department of Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7228, USA
Am Surg 71:539-44; discussion 544-5. 2005..There was no mortality in our series. In this series, SSCE was an effective first-line therapy for LGIB. Rebleeding and ischemia rates were low...
Optimal outcomes for patients with blunt cerebrovascular injury (BCVI): tailoring treatment to the lesionJennifer M DiCocco
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 212:549-57; discussion 557-9. 2011..Endovascular therapy in these lesions has increased without reports of outcomes. We sought to determine ischemic stroke and death rates after BCVI with and without endovascular treatment...
A survey of American Association for the Surgery of Trauma member practices in the management of blunt splenic injuryBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:1026-31. 2011....
Long-term follow-up of abdominal wall reconstruction after planned ventral hernia: a 15-year experienceJennifer M DiCocco
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38162, USA
J Am Coll Surg 210:686-95, 695-8. 2010....
Blood transfusion is an independent predictor of increased mortality in nonoperatively managed blunt hepatic and splenic injuriesWilliam P Robinson
Section of Trauma, Burns, and Critical Care, Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA
J Trauma 58:437-44; discussion 444-5. 2005..Transfusion-associated mortality risk was highest in the subset of patients managed nonoperatively. Prospective examination of transfusion practices in treatment algorithms of blunt hepatic and splenic injuries is warranted...
The microbiology of secondary and postoperative pancreatic infections: implications for antimicrobial managementStephen W Behrman
Department of Surgery, University of Tennessee Health Science Center, Memphis, 910 Madison Ave, Ste 208, Memphis, TN 38163, USA
Arch Surg 146:613-9. 2011..We hypothesized that our findings might alter the antimicrobial management of these patients...
Blunt cerebrovascular injury screening with 32-channel multidetector computed tomography: more slices still don't cut itJennifer M DiCocco
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
Ann Surg 253:444-50. 2011..We sought to determine the diagnostic accuracy of computed tomographic angiography (CTA) using 32-channel multidetector computed tomography for blunt cerebrovascular injuries (BCVIs)...
Routine follow-up imaging is unnecessary in the management of blunt hepatic injuryJordy C Cox
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 59:1175-8; discussion 1178-80. 2005..Follow-up scans are indicated for patients who develop signs or symptoms suggestive of hepatic abnormality...
Impact of motorcycle helmets and state laws on society's burden: a national studyMartin A Croce
Department of Surgery University of Tennessee Health Science Center Memphis, TN, USA
Ann Surg 250:390-4. 2009..To analyze a large national database, the National Trauma Data Bank, regarding the contribution of motorcycle helmet use to outcome and the efficacy of state helmet laws...
Intra-abdominal sepsis following pancreatic resection: incidence, risk factors, diagnosis, microbiology, management, and outcomeStephen W Behrman
Department of Surgery, University of Tennessee, Memphis, Tennessee 38163, USA
Am Surg 74:572-8; discussion 578-9. 2008....
Measurement of free and bound fractions of extracellular ATP in biological solutions using bioluminescenceChristelle D Douillet
Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7228, USA
Luminescence 20:435-41. 2005..Heating releases bound ATP, enabling accurate luminometric measurement of total extracellular ATP (free and bound) in biological samples...
Enteral feeding preserves mucosal immunity despite in vivo MAdCAM-1 blockade of lymphocyte homingShigeo Ikeda
Department of Surgery, The University of Wisconsin Madison, 600 Highland Avenue, Madison, WI 53792 7375, USA
Ann Surg 237:677-85; discussion 685. 2003....
Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organsChristelle D Douillet
Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7228, USA
Am J Respir Cell Mol Biol 32:52-8. 2005..MV alters the BAL adenyl-nucleotide profile and purinoceptor patterns in lung, liver, and kidney. PEEP normalizes the BAL nucleotide profile and receptor patterns in lung and extrapulmonary tissues...
Mucosal immunity preservation with bombesin or glutamine is not dependent on mucosal addressin cell adhesion molecule-1 expressionBen L Zarzaur
Department of Surgery, University of Wisconsin, Madison 53792-7375, USA
JPEN J Parenter Enteral Nutr 26:265-70; discussion 270. 2002..CONCLUSIONS: Although MAdCAM-1 is considered the gateway molecule for cell entry into mucosal immunity, this does not seem to be the mechanism for mucosal immunity preservation in nonenterally fed mice receiving bombesin or glutamine...
The evolution of blunt splenic injury: resolution and progressionStephanie A Savage
Department of General Surgery, Wilford Hall Medical Center, Lackland AFB, Texas, USA
J Trauma 64:1085-91; discussion 1091-2. 2008..Our hypothesis was that time to healing is related to severity of BSI...
