Research Topics
| Zuoshuang XiangSummaryAffiliation: University of Michigan Country: USA Publications
| Collaborators
|
Detail Information
Publications
BBP: Brucella genome annotation with literature mining and curationZuoshuang Xiang
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
BMC Bioinformatics 7:347. 2006..It is further hypothesized that literature-based Brucella gene annotation would increase understanding of complicated Brucella pathogenesis mechanisms...
Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association networkJunguk Hur
Bioinformatics Program, University of Michigan, Ann Arbor, MI 48109, USA
BMC Immunol 12:49. 2011..As a test case, we have examined vaccines for Brucella, the causative agent of brucellosis in humans and animals...
Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine developmentYongqun He
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Biomed Biotechnol 2010:297505. 2010..Our results indicate that Vaxign is an accurate and efficient vaccine design program...
VIOLIN: vaccine investigation and online information networkZuoshuang Xiang
Unit for Laboratory Animal Medicine, Department of Microbiology and Immunology, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA
Nucleic Acids Res 36:D923-8. 2008..VIOLIN is publicly available at http://www.violinet.org...
Proinflammatory caspase-2-mediated macrophage cell death induced by a rough attenuated Brucella suis strainFang Chen
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Infect Immun 79:2460-9. 2011..This unique cell death differs from apoptosis, which is not proinflammatory. It is also different from classical pyroptosis, which is caspase-1 mediated...
Protegen: a web-based protective antigen database and analysis systemBrian Yang
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
Nucleic Acids Res 39:D1073-8. 2011..Protegen is publically available at http://www.violinet.org/protegen...
Pathobiology and management of laboratory rodents administered CDC category A agentsYongqun He
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, USA
Comp Med 57:18-32. 2007....
PHIDIAS: a pathogen-host interaction data integration and analysis systemZuoshuang Xiang
Unit for Laboratory Animal Medicine, University of Michigan, 1150 W Medical Dr, Ann Arbor, MI 48109, USA
Genome Biol 8:R150. 2007..In addition, PHIDIAS allows submission, search and analysis of PHI genes and molecular networks curated from peer-reviewed literature. PHIDIAS is publicly available at http://www.phidias.us...
Mining of vaccine-associated IFN-? gene interaction networks using the Vaccine OntologyArzucan Ozgür
Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
J Biomed Semantics 2:S8. 2011..The Vaccine Ontology (VO) contains a hierarchy of vaccine names. It is hypothesized that the application of VO will enhance the prediction of IFN-? and vaccine-mediated gene interaction network...
miniTUBA: medical inference by network integration of temporal data using Bayesian analysisZuoshuang Xiang
Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, USA
Bioinformatics 23:2423-32. 2007..No software pipeline currently exists for interpretation and inference of dynamic Bayesian networks learned from biomedical and clinical data...
CRCView: a web server for analyzing and visualizing microarray gene expression data using model-based clusteringZuoshuang Xiang
Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, USA
Bioinformatics 23:1843-5. 2007..It allows flexible input data format, rich graphical illustration as well as integrated GO term based annotation/interpretation of clustering results. Availability: http://helab.bioinformatics.med.umich.edu/crcview/...
Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine developmentSamantha Sayers
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Biomed Biotechnol 2012:831486. 2012..To support data exchange, the information of vaccine adjuvants is stored in the Vaccine Ontology (VO) in the Web Ontology Language (OWL) format...
Literature-based discovery of IFN-gamma and vaccine-mediated gene interaction networksArzucan Ozgür
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA
J Biomed Biotechnol 2010:426479. 2010..Literature evidence was manually curated for the IFN-gamma relatedness of 56 genes and vaccine development relatedness for 52 genes. This study also generated many new hypotheses worth further experimental studies...
OntoFox: web-based support for ontology reuseZuoshuang Xiang
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
BMC Res Notes 3:175. 2010..abstract:..
Brucellosis Ontology (IDOBRU) as an extension of the Infectious Disease OntologyYu Lin
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Biomed Semantics 2:9. 2011..abstract:..
Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLINYongqun He
Unit for Laboratory Animal Medicine, Department of Microbiology and Immunology, and Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Immunome Res 6:S5. 2010..The use of VIOLIN provides a general approach that can be applied for analyses of vaccines against other pathogens and infection diseases...
