Research Topics
| R L WortmannSummaryAffiliation: University of Oklahoma Health Sciences Center Country: USA Publications
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Detail Information
Publications
Gout and hyperuricemiaRobert L Wortmann
Department of Internal Medicine, The University of Oklahoma College of Medicine, Tulsa 74135, USA
Curr Opin Rheumatol 14:281-6. 2002..Uricosuric agents are also effective urate-lowering agents and provide an alternative to allopurinol. Strategies to treat patients who are sensitive to allopurinol continue to evolve...
Myotoxicity associated with lipid-lowering drugsAlan N Baer
Division of Allergy, Immunology, and Rheumatology, Department of Medicine, University at Buffalo, SUNY, Erie County Medical Center, Buffalo, New York 14215, USA
Curr Opin Rheumatol 19:67-73. 2007..Progress in our understanding of this form of myotoxicity is reviewed...
The clinical laboratory evaluation of the patient with noninflammatory myopathyR L Wortmann
Department of Internal Medicine, The University of Oklahoma College of Medicine Tulsa, 4502 East 41st Street, Tulsa, OK, 74135, USA
Curr Rheumatol Rep 3:310-6. 2001..Reports published in the past year have improved and expanded our understanding of the numerous noninflammatory myopathies and how these tools can be used more effectively...
Lipid-lowering agents and myopathyRobert L Wortmann
Department of Internal Medicine, The University of Oklahoma College of Medicine, Tulsa, 74135 2512, USA
Curr Opin Rheumatol 14:643-7. 2002..Consequently, the total dosage of lipid-lowering drug consumed, the concomitant use of other medications that affect their blood levels, and the individual's specific drug-metabolizing enzyme profile may contribute to this toxicity...
Treatment of acute gouty arthritis: one physician's approach and where this management stands relative to developments in the fieldRobert L Wortmann
Department of Internal Medicine, The University of Oklahoma College of Medicine, 4502 East 41st Street, Tulsa, OK 74137, USA
Curr Rheumatol Rep 6:235-9. 2004..These observations allow a better understanding of the mechanisms of action of these agents and provide the rationale for using them in combination in severe or refractory cases...
Recent advances in the management of gout and hyperuricemiaRobert L Wortmann
Department of Internal Medicine, University of Oklahoma College of Medicine, Tulsa, Oklahoma 74135, USA
Curr Opin Rheumatol 17:319-24. 2005..To review the recent advances in the management of gout and hyperuricemia...
Advances in the management of gout and hyperuricaemiaT K Hoskison
Department of Internal Medicine, The University of Oklahoma College of Medicine-Tulsa, 4502 East 41st Street, Tulsa, OK 74135, USA
Scand J Rheumatol 35:251-60. 2006..While patient education remains a cornerstone to ensure compliance, other quality indicators for the management of this disease have been reported and should guide the clinician in the treatment of gout and result in improved care...
Management of gout in older adults: barriers to optimal controlKarl T Hoskison
Department of Internal Medicine, The University of Oklahoma College of Medicine, Tulsa, Oklahoma 74135, USA
Drugs Aging 24:21-36. 2007....
Differentiating idiopathic inflammatory myopathies from metabolic myopathiesRobert L Wortmann
Department of Internal Medicine, University of Oklahoma College of Medicine Tulsa, 4502 East 41st Street, Tulsa, OK 74137, USA
Rheum Dis Clin North Am 28:759-78. 2002..These are essential factors in improving genetic counseling and eventually the therapy of these serious, and currently incurable, disorders...
Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with goutMichael A Becker
Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
Arthritis Rheum 52:916-23. 2005..0 mg/dl)...
Febuxostat compared with allopurinol in patients with hyperuricemia and goutMichael A Becker
University of Chicago Pritzker School of Medicine, Chicago, USA
N Engl J Med 353:2450-61. 2005..Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase, is a potential alternative to allopurinol for patients with hyperuricemia and gout...
The management of gout: it should be crystal clearRobert L Wortmann
J Rheumatol 33:1921-2. 2006
Genetic risk factors associated with lipid-lowering drug-induced myopathiesGeorgirene D Vladutiu
Department of Pediatrics, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 936 Delaware Avenue, Buffalo, New York 14209, USA
Muscle Nerve 34:153-62. 2006..The effect of statins on energy metabolism combined with a genetic susceptibility to triggering of muscle symptoms may account for myopathic outcomes in certain high-risk groups...
Dose-related statin myopathy: is it an issue?Robert L Wortmann
Cleve Clin J Med 72:751-3, 756. 2005
