Stephanie E Wohlgemuth

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise
    Stephanie Eva Wohlgemuth
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610, USA
    Exp Gerontol 45:138-48. 2010
  2. ncbi Autophagy in the heart and liver during normal aging and calorie restriction
    Stephanie E Wohlgemuth
    Biochemistry of Aging Laboratory, Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32610 0107, USA
    Rejuvenation Res 10:281-92. 2007
  3. ncbi Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction
    Emanuele Marzetti
    Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610 0143, USA
    Mech Ageing Dev 130:272-80. 2009
  4. ncbi Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy
    Jinze Xu
    Department of Aging and Geriatric Research, Division of Biology of Aging, Genomics and Biomarkers Core of the Institute on Aging, University of Florida, Gainesville, Florida 32611, USA
    Exp Gerontol 47:100-8. 2012
  5. ncbi Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy
    Emanuele Marzetti
    Department of Aging and Geriatrics, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610 0143, USA
    Biochim Biophys Acta 1800:235-44. 2010
  6. ncbi Mitochondrial iron accumulation with age and functional consequences
    Arnold Y Seo
    Department of Aging and Geriatrics, Division of Biology of Aging, Genomics and Biomarkers Core of the Institute on Aging, University of Florida, Gainesville, FL 32611, USA
    Aging Cell 7:706-16. 2008
  7. ncbi Effects of short-term GH supplementation and treadmill exercise training on physical performance and skeletal muscle apoptosis in old rats
    Emanuele Marzetti
    Department of Aging and Geriatrics, Institute on Aging, Division of Biology of Aging, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
    Am J Physiol Regul Integr Comp Physiol 294:R558-67. 2008
  8. ncbi Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives
    Emanuele Marzetti
    Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610 0143, USA
    Clin Geriatr Med 25:715-32, ix. 2009
  9. ncbi Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy
    Thomas W Buford
    Institute on Aging, University of Florida, Gainesville, FL 32611, United States
    Ageing Res Rev 9:369-83. 2010
  10. ncbi An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women
    Stephanie E Wohlgemuth
    Department of Aging and Geriatrics, Institute on Aging, College of Medicine, University of Florida, Gainesville, FL 32611 0910, USA
    Rejuvenation Res 14:315-24. 2011

Detail Information

Publications15

  1. ncbi Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise
    Stephanie Eva Wohlgemuth
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610, USA
    Exp Gerontol 45:138-48. 2010
    ..We conclude that mild CR attenuates the age-related impairment of autophagy in rodent skeletal muscle, which might be one of the mechanisms by which CR attenuates age-related cellular damage and cell death in skeletal muscle in vivo...
  2. ncbi Autophagy in the heart and liver during normal aging and calorie restriction
    Stephanie E Wohlgemuth
    Biochemistry of Aging Laboratory, Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32610 0107, USA
    Rejuvenation Res 10:281-92. 2007
    ..Thus, calorie restriction may mediate some of its beneficial effects by stimulating autophagy in the heart, indicating the potential for cardioprotective therapies...
  3. ncbi Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction
    Emanuele Marzetti
    Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610 0143, USA
    Mech Ageing Dev 130:272-80. 2009
    ..Preservation of IL-15 signaling by CR may therefore represent a further mechanism contributing to the anti-aging effect of this dietary intervention in skeletal muscle...
  4. ncbi Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy
    Jinze Xu
    Department of Aging and Geriatric Research, Division of Biology of Aging, Genomics and Biomarkers Core of the Institute on Aging, University of Florida, Gainesville, Florida 32611, USA
    Exp Gerontol 47:100-8. 2012
    ..In conclusion, advanced age is associated with disruption of muscle iron metabolism which is further perturbed by disuse and persists over a longer time period...
  5. ncbi Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy
    Emanuele Marzetti
    Department of Aging and Geriatrics, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610 0143, USA
    Biochim Biophys Acta 1800:235-44. 2010
    ..Furthermore, a translational effort is required to determine the role played by apoptosis in the pathogenesis of sarcopenia and disuse-induced muscle loss in human subjects...
  6. ncbi Mitochondrial iron accumulation with age and functional consequences
    Arnold Y Seo
    Department of Aging and Geriatrics, Division of Biology of Aging, Genomics and Biomarkers Core of the Institute on Aging, University of Florida, Gainesville, FL 32611, USA
    Aging Cell 7:706-16. 2008
    ..Overall, our data suggest that age-dependent accumulation of mitochondrial iron may increase mitochondrial dysfunction and oxidative damage,thereby enhancing the susceptibility to apoptosis...
  7. ncbi Effects of short-term GH supplementation and treadmill exercise training on physical performance and skeletal muscle apoptosis in old rats
    Emanuele Marzetti
    Department of Aging and Geriatrics, Institute on Aging, Division of Biology of Aging, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
    Am J Physiol Regul Integr Comp Physiol 294:R558-67. 2008
    ..In contrast, short-term administration of GH late in life does not provide any protection against functional decline or muscle aging and may even accelerate apoptosis in slow-twitch muscles, such as the soleus...
  8. ncbi Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives
    Emanuele Marzetti
    Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610 0143, USA
    Clin Geriatr Med 25:715-32, ix. 2009
    ..Results from ongoing clinical trials will reveal whether the intriguing alternative of CR mimetics represents a safe and effective strategy to promote cardiovascular health and delay cardiac aging in humans...
  9. ncbi Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy
    Thomas W Buford
    Institute on Aging, University of Florida, Gainesville, FL 32611, United States
    Ageing Res Rev 9:369-83. 2010
    ..Elucidating biochemical pathways related to accelerated muscle atrophy may allow for improved discovery of therapeutic treatments related to sarcopenia...
  10. ncbi An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women
    Stephanie E Wohlgemuth
    Department of Aging and Geriatrics, Institute on Aging, College of Medicine, University of Florida, Gainesville, FL 32611 0910, USA
    Rejuvenation Res 14:315-24. 2011
    ..In conclusion, although exploratory in nature, this study is among the first to report the stimulation of cellular quality control mechanisms elicited by a weight loss and exercise program in older obese women...
  11. ncbi Age-related differences in lower extremity tissue compartments and associations with physical function in older adults
    Thomas W Buford
    Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32607, USA
    Exp Gerontol 47:38-44. 2012
    ..264, p=0.001) and 4-meter gait speed (r(2)=0.187, p=0.007). These data suggest that aging affects all lower extremity compartments, but femoral muscle mass is the major compartment associated with physical function in older adults...
  12. ncbi Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging
    Emanuele Marzetti
    Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, USA
    ScientificWorldJournal 10:340-9. 2010
    ....
  13. ncbi Oxygen consumption in weakly electric Neotropical fishes
    David Julian
    Department of Zoology, University of Florida, Gainesville, FL 32611 8525, USA
    Oecologia 137:502-11. 2003
    ..83+/-0.49-fold (mean+/-SD). This suggests that the increased metabolic cost of scan swimming could restrict gymnotiforms with wave-type EODs from hypoxic habitats...
  14. ncbi Enzymatic hydrogen sulfide production in marine invertebrate tissues
    David Julian
    Romberg Tiburon Center for Environmental Studies, San Francisco State University, San Francisco, CA, USA
    Comp Biochem Physiol A Mol Integr Physiol 133:105-15. 2002
    ..marina was doubled by the addition of a second thiol substrate (2.5 mmol l(-1) 2-mercaptoethanol), suggesting the presence of an 'activated serine sulfhydrase pathway', which had previously been demonstrated only in some microfauna...
  15. ncbi Mitochondrial depolarization following hydrogen sulfide exposure in erythrocytes from a sulfide-tolerant marine invertebrate
    David Julian
    Department of Zoology, University of Florida, Gainesville, FL 32611 8525, USA
    J Exp Biol 208:4109-22. 2005
    ....